|
1
|
Scully RE: Ovarian tumors. A review. Am J
Pathol. 87:686–720. 1977.PubMed/NCBI
|
|
2
|
Sakr S, Abdulfatah E, Thomas S, Al-Wahab
Z, Beydoun R, Morris R, Ali-Fehmi R and Bandyopadhyay S: Granulosa
cell tumors: Novel predictors of recurrence in early-stage
patients. Int J Gynecol Pathol. 36:240–252. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Colombo N, Parma G, Zanagnolo V and
Insinga A: Management of ovarian stromal cell tumors. J Clin Oncol.
25:2944–2951. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Jamieson S and Fuller PJ: Molecular
pathogenesis of granulosa cell tumors of the ovary. Endocr Rev.
33:109–144. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Vassal G, Flamant F, Caillaud JM, Demeocq
F, Nihoul-Fekete C and Lemerle J: Juvenile granulosa cell tumor of
the ovary in children: A clinical study of 15 cases. J Clin Oncol.
6:990–995. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Nasu K, Fukuda J, Yoshimatsu J, Takai N,
Kashima K and Narahara H: Granulosa cell tumor associated with
secondary amenorrhea and serum luteinizing hormone elevation. Int J
Clin Oncol. 12:228–230. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Szewczuk W, Szewczuk O, Czajkowski K,
Grala B and Semczuk A: Ovarian adult-type granulosa cell tumor
concomitant with simple endometrial hyperplasia: A case study with
selected immunohistochemistry. J Int Med Res 300060519886984.
2019.(Epub ahead of print). View Article : Google Scholar
|
|
8
|
Levin G, Zigron R, Haj-Yahya R, Matan LS
and Rottenstreich A: Granulosa cell tumor of ovary: A systematic
review of recent evidence. Eur J Obstet Gynecol Reprod Biol.
225:57–61. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Schumer ST and Cannistra SA: Granulosa
cell tumor of the ovary. J Clin Oncol. 21:1180–1189. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Roth LM, Lyu B and Cheng L: Perspectives
on testicular sex cord-stromal tumors and those composed of both
germ cells and sex cord-stromal derivatives with a comparison to
corresponding ovarian neoplasms. Hum Pathol. 65:1–14. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Young RH: Sex cord-stromal tumors of the
ovary and testis: Their similarities and differences with
consideration of selected problems. Mod Pathol. 18 (Suppl
2):S81–S98. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Fang X, Ni N, Gao Y, Vincent DF, Bartholin
L and Li Q: A novel mouse model of testicular granulosa cell
tumors. Mol Hum Reprod. 24:343–356. 2018.PubMed/NCBI
|
|
13
|
Cheng L, Albers P, Berney DM, Feldman DR,
Daugaard G, Gilligan T and Looijenga LHJ: Testicular cancer. Nat
Rev Dis Primers. 4:292018. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Moch H, Cubilla AL, Humphrey PA, Reuter VE
and Ulbright TM: The 2016 WHO classification of tumours of the
urinary system and male genital organs-Part A: Renal, penile, and
testicular tumours. Eur Urol. 70:93–105. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Idrees MT, Ulbright TM, Oliva E, Young RH,
Montironi R, Egevad L, Berney D, Srigley JR, Epstein JI and Tickoo
SK; Members of the International Society of Urological Pathology
Testicular Tumour Panel, : The World Health Organization 2016
classification of testicular non-germ cell tumours: A review and
update from the International Society of Urological Pathology
Testis Consultation Panel. Histopathology. 70:513–521. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Al-Agha OM and Axiotis CA: An in-depth
look at Leydig cell tumor of the testis. Arch Pathol Lab Med.
131:311–317. 2007.PubMed/NCBI
|
|
17
|
Kim I, Young RH and Scully RE: Leydig cell
tumors of the testis. A clinicopathological analysis of 40 cases
and review of the literature. Am J Surg Pathol. 9:177–192. 1985.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Boyer A, Paquet M, Lague MN, Hermo L and
Boerboom D: Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in
testicular stromal cells causes granulosa cell tumor of the testis.
Carcinogenesis. 30:869–878. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Richards JS, Fan HY, Liu Z, Tsoi M, Lague
MN, Boyer A and Boerboom D: Either Kras activation or Pten loss
similarly enhance the dominant-stable CTNNB1-induced genetic
program to promote granulosa cell tumor development in the ovary
and testis. Oncogene. 31:1504–1520. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zugor V, Labanaris AP, Witt J, Seidler A,
Weingartner K and Schott GE: Congenital juvenile granulosa cell
tumor of the testis in newborns. Anticancer Res. 30:1731–1734.
2010.PubMed/NCBI
|
|
21
|
Kao CS, Cornejo KM, Ulbright TM and Young
RH: Juvenile granulosa cell tumors of the testis: A
clinicopathologic study of 70 cases with emphasis on its wide
morphologic spectrum. Am J Surg Pathol. 39:1159–1169. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Raju U, Fine G, Warrier R, Kini R and
Weiss L: Congenital testicular juvenile granulosa cell tumor in a
neonate with X/XY mosaicism. Am J Surg Pathol. 10:577–583. 1986.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Young RH, Lawrence WD and Scully RE:
Juvenile granulosa cell tumor-another neoplasm associated with
abnormal chromosomes and ambiguous genitalia. A report of three
cases. Am J Surg Pathol. 9:737–743. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wu JT, Book L and Sudar K: Serum alpha
fetoprotein (AFP) levels in normal infants. Pediatr Res. 15:50–52.
1981. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Dieckmann KP, Bertolini J and Wulfing C:
Adult granulosa cell tumor of the testis: A case report with a
review of the literature. Case Rep Urol.
2019:71561542019.PubMed/NCBI
|
|
26
|
Cornejo KM and Young RH: Adult granulosa
cell tumors of the testis: A report of 32 cases. Am J Surg Pathol.
38:1242–1250. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Jimenez-Quintero LP, Ro JY, Zavala-Pompa
A, Amin MB, Tetu B, Ordonez NG and Ayala AG: Granulosa cell tumor
of the adult testis: A clinicopathologic study of seven cases and a
review of the literature. Hum Pathol. 24:1120–1125. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Suppiah A, Musa MM, Morgan DR and North
AD: Adult granulosa cell tumour of the testis and bony metastasis.
A report of the first case of granulosa cell tumour of the testicle
metastasising to bone. Urol Int. 75:91–93. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Hanson JA and Ambaye AB: Adult testicular
granulosa cell tumor: A review of the literature for
clinicopathologic predictors of malignancy. Arch Pathol Lab Med.
135:143–146. 2011.PubMed/NCBI
|
|
30
|
Pisarska MD, Barlow G and Kuo FT:
Minireview: Roles of the forkhead transcription factor FOXL2 in
granulosa cell biology and pathology. Endocrinology. 152:1199–1208.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Uhlenhaut NH, Jakob S, Anlag K,
Eisenberger T, Sekido R, Kress J, Treier AC, Klugmann C, Klasen C,
Holter NI, et al: Somatic sex reprogramming of adult ovaries to
testes by FOXL2 ablation. Cell. 139:1130–1142. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kalfa N, Fellous M, Boizet-Bonhoure B,
Patte C, Duvillard P, Pienkowski C, Jaubert F, Ecochard A and
Sultan C: Aberrant expression of ovary determining gene FOXL2 in
the testis and juvenile granulosa cell tumor in children. J Urol.
180 (Suppl 4):S1810–S1813. 2008. View Article : Google Scholar
|
|
33
|
Shah SP, Kobel M, Senz J, Morin RD, Clarke
BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, et al:
Mutation of FOXL2 in granulosa-cell tumors of the ovary. N Engl J
Med. 360:2719–2729. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Nonis D, McTavish KJ and Shimasaki S:
Essential but differential role of FOXL2wt and FOXL2C134W in GDF-9
stimulation of follistatin transcription in co-operation with Smad3
in the human granulosa cell line COV434. Mol Cell Endocrinol.
372:42–48. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Cheng JC, Chang HM, Qiu X, Fang L and
Leung PC: FOXL2-induced follistatin attenuates activin A-stimulated
cell proliferation in human granulosa cell tumors. Biochem Biophys
Res Commun. 443:537–542. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Leung DTH, Fuller PJ and Chu S: Impact of
FOXL2 mutations on signaling in ovarian granulosa cell tumors. Int
J Biochem Cell Biol. 72:51–54. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kim JH, Yoon S, Park M, Park HO, Ko JJ,
Lee K and Bae J: Differential apoptotic activities of wild-type
FOXL2 and the adult-type granulosa cell tumor-associated mutant
FOXL2 (C134W). Oncogene. 30:1653–1663. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Fleming NI, Knower KC, Lazarus KA, Fuller
PJ, Simpson ER and Clyne CD: Aromatase is a direct target of FOXL2:
C134W in granulosa cell tumors via a single highly conserved
binding site in the ovarian specific promoter. PLoS One.
5:e143892010. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Lima JF, Jin L, de Araujo AR,
Erikson-Johnson MR, Oliveira AM, Sebo TJ, Keeney GL and Medeiros F:
FOXL2 mutations in granulosa cell tumors occurring in males. Arch
Pathol Lab Med. 136:825–828. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Fuller PJ, Chu S, Fikret S and Burger HG:
Molecular pathogenesis of granulosa cell tumours. Mol Cell
Endocrinol. 191:89–96. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Kim SY: Insights into granulosa cell
tumors using spontaneous or genetically engineered mouse models.
Clin Exp Reprod Med. 43:1–8. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Matzuk MM, Finegold MJ, Su JG, Hsueh AJ
and Bradley A: Alpha-inhibin is a tumour-suppressor gene with
gonadal specificity in mice. Nature. 360:313–319. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y,
Chen M, Cui X, Duo S, Tang F and Gao F: β-Catenin directs the
transformation of testis Sertoli cells to ovarian granulosa-like
cells by inducing Foxl2 expression. J Biol Chem. 292:17577–17586.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Pangas SA, Li X, Umans L, Zwijsen A,
Huylebroeck D, Gutierrez C, Wang D, Martin JF, Jamin SP, Behringer
RR, et al: Conditional deletion of Smad1 and Smad5 in somatic cells
of male and female gonads leads to metastatic tumor development in
mice. Mol Cell Biol. 28:248–257. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ying SY: Inhibins, activins, and
follistatins: Gonadal proteins modulating the secretion of
follicle-stimulating hormone. Endocr Rev. 9:267–293. 1988.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
O'Connor AE and De Kretser DM: Inhibins in
normal male physiology. Semin Reprod Med. 22:177–185. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Kumar TR, Wang Y and Matzuk MM:
Gonadotropins are essential modifier factors for gonadal tumor
development in inhibin-deficient mice. Endocrinology.
137:4210–4216. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Cipriano SC, Chen L, Burns KH, Koff A and
Matzuk MM: Inhibin and p27 interact to regulate gonadal
tumorigenesis. Mol Endocrinol. 15:985–996. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Burns KH, Agno JE, Sicinski P and Matzuk
MM: Cyclin D2 and p27 are tissue-specific regulators of
tumorigenesis in inhibin alpha knockout mice. Mol Endocrinol.
17:2053–2069. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Li Q, Graff JM, O'Connor AE, Loveland KL
and Matzuk MM: SMAD3 regulates gonadal tumorigenesis. Mol
Endocrinol. 21:2472–2486. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Klaus A and Birchmeier W: Wnt signalling
and its impact on development and cancer. Nat Rev Cancer.
8:387–398. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Boerboom D, Paquet M, Hsieh M, Liu J,
Jamin SP, Behringer RR, Sirois J, Taketo MM and Richards JS:
Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa
cell tumor development. Cancer Res. 65:9206–9215. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Mitsiades CS, Mitsiades N and Koutsilieris
M: The Akt pathway: Molecular targets for anti-cancer drug
development. Curr Cancer Drug Targets. 4:235–256. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Hay N: The Akt-mTOR tango and its
relevance to cancer. Cancer Cell. 8:179–183. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Haigis KM: KRAS alleles: The devil is in
the detail. Trends Cancer. 3:686–697. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Fan HY, Shimada M, Liu Z, Cahill N, Noma
N, Wu Y, Gossen J and Richards JS: Selective expression of KrasG12D
in granulosa cells of the mouse ovary causes defects in follicle
development and ovulation. Development. 135:2127–2137. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Hannenhalli S and Kaestner KH: The
evolution of Fox genes and their role in development and disease.
Nat Rev Genet. 10:233–240. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Uhlenhaut NH and Treier M: Forkhead
transcription factors in ovarian function. Reproduction.
142:489–495. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Belli M, Secchi C, Stupack D and Shimasaki
S: FOXO1 negates the cooperative action of FOXL2C134W
and SMAD3 in CYP19 expression in HGrC1 cells by sequestering SMAD3.
J Endocr Soc. 3:2064–2081. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Liu Z, Ren YA, Pangas SA, Adams J, Zhou W,
Castrillon DH, Wilhelm D and Richards JS: FOXO1/3 and PTEN
depletion in granulosa cells promotes ovarian granulosa cell tumor
development. Mol Endocrinol. 29:1006–1024. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Massague J: TGF-beta signal transduction.
Annu Rev Biochem. 67:753–791. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Fang X, Gao Y and Li Q: SMAD3 activation:
A converging point of dysregulated TGF-Beta superfamily signaling
and genetic aberrations in granulosa cell tumor development? Biol
Reprod. 95:1052016. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Massague J: TGFbeta in cancer. Cell.
134:215–230. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Gao Y, Vincent DF, Davis AJ, Sansom OJ,
Bartholin L and Li Q: Constitutively active transforming growth
factor β receptor 1 in the mouse ovary promotes tumorigenesis.
Oncotarget. 7:40904–40918. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Boyer A, Hermo L, Paquet M, Robaire B and
Boerboom D: Seminiferous tubule degeneration and infertility in
mice with sustained activation of WNT/CTNNB1 signaling in sertoli
cells. Biol Reprod. 79:475–485. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Jamin SP, Arango NA, Mishina Y, Hanks MC
and Behringer RR: Requirement of Bmpr1a for Mullerian duct
regression during male sexual development. Nat Genet. 32:408–410.
2002. View
Article : Google Scholar : PubMed/NCBI
|
|
67
|
Tanwar PS, Kaneko-Tarui T, Zhang L, Rani
P, Taketo MM and Teixeira J: Constitutive WNT/beta-catenin
signaling in murine Sertoli cells disrupts their differentiation
and ability to support spermatogenesis. Biol Reprod. 82:422–432.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Albrecht KH and Eicher EM: Evidence that
Sry is expressed in pre-Sertoli cells and Sertoli and granulosa
cells have a common precursor. Dev Biol. 240:92–107. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Muzumdar MD, Tasic B, Miyamichi K, Li L
and Luo L: A global double-fluorescent Cre reporter mouse. Genesis.
45:593–605. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Snyder CS, Harrington AR, Kaushal S, Mose
E, Lowy AM, Hoffman RM and Bouvet M: A dual-color genetically
engineered mouse model for multispectral imaging of the pancreatic
microenvironment. Pancreas. 42:952–958. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Gammon K: Mathematical modelling:
Forecasting cancer. Nature. 491:S66–S67. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Beerenwinkel N, Schwarz RF, Gerstung M and
Markowetz F: Cancer evolution: Mathematical models and
computational inference. Syst Biol. 64:e1–e25. 2015. View Article : Google Scholar : PubMed/NCBI
|
