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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2020 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

7‑dehydrocholesterol suppresses melanoma cell proliferation and invasion via Akt1/NF‑κB signaling

Jia Liu, Feiliang Zhong, Lei Cao, Ruiying Zhu, Junze Qu, Lin Yang, Tingting Chen, Yunlong Hu, Ying Wang, Mingdong Yao, Wenhai Xiao, Chun Li, Bo Li, Yingjin Yuan
Article Number: 398
Published online on: 29 October 2020

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Article Open Access

Immune cell infiltration and cytokine secretion analysis reveal a non-inflammatory microenvironment of medulloblastoma

Shuo Diao, Chunyu Gu, Hongwei Zhang, Chunjiang Yu
Article Number: 397
Published online on: 29 October 2020

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Review Open Access

Early palliative care of non‑small cell lung cancer in the context of immunotherapy (Review)

Małgorzata Pieniążek, Piotr Pawlak, Barbara Radecka
Article Number: 396
Published online on: 29 October 2020

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Article Open Access

Immunohistochemical expression of insulin‑like growth factor‑1Ec in primary endometrial carcinoma: Association with PTEN, p53 and survivin expression

Aggelis Stavropoulos, Michail Varras, Anastassios Philippou, Thivi Vasilakaki, Viktoria-Konstantina Varra, Fani-Niki Varra, Aikaterini Tsavari, Andreas C. Lazaris, Michael Koutsilieris
Article Number: 395
Published online on: 29 October 2020

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Article Open Access

Involvement of the Wnt/β‑Catenin signaling pathway in the heterogenous nuclear ribonucleoprotein K‑driven inhibition of proliferation and migration in head and neck squamous cell carcinoma

Hongfei Liu, Xiaohong Chen, Xingjiu Yang, Mengyuan Li, Wenlong Zhang, Guoxin Zhang, Xiangwen Zhan, Lin Cao, Weisha Li, Zhigang Huang, Ran Gao
Article Number: 394
Published online on: 29 October 2020

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Article

Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction

Kazuya Nishii, Kadoaki Ohashi, Tomoki Tamura, Kiichiro Ninomiya, Takehiro  Matsubara, Satoru Senoo, Hirohisa Kano, Hiromi Watanabe, Naohiro  Oda, Go Makimoto, Hisao Higo, Yuka Kato, Takashi Ninomiya, Toshio  Kubo, Hiromasa Yamamoto, Shuta Tomida, Katsuyuki Hotta, Masahiro  Tabata, Shinichi Toyooka, Yoshinobu Maeda, Katsuyuki Kiura
Article Number: 393
Published online on: 29 October 2020

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Article

Expression of TRPC1 and SBEM protein in breast cancer tissue and its relationship with clinicopathological features and prognosis of patients

Yongqing Zhang, Xiaoqin Lun, Weiling Guo
Article Number: 392
Published online on: 29 October 2020

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Article Open Access

Thiostrepton and miR‑216b synergistically promote osteosarcoma cell cytotoxicity and apoptosis by targeting FoxM1

Xiaobing Cai, Wenyu Xiao, Juexin Shen, Hui Lian, Yi Lu, Xianmiao Liu, Jisheng Gu
Article Number: 391
Published online on: 29 October 2020

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Article Open Access

Downregulated microRNA‑140‑5p expression regulates apoptosis, migration and invasion of lung cancer cells by targeting zinc finger protein 800 Retraction in /10.3892/ol.2024.14727

Enqing Zhuo, Changqing Cai, Wenzhe Liu, Kunsong Li, Wenzhen Zhao
Article Number: 390
Published online on: 29 October 2020

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Article Open Access

Neurensin‑2 promotes proliferation, invasion and migration of colorectal cancer cells via interaction with SOX12

Gang Wang, Kai Yang
Article Number: 389
Published online on: 29 October 2020

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Article Open Access

Hypoxia-induced circular RNA hsa_circ_0008450 accelerates hepatocellular cancer progression via the miR-431/AKAP1 axis

Qiajun Du, Jie Han, Shan Gao, Shangdi Zhang, Yunyan Pan
Article Number: 388
Published online on: 29 October 2020

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Article Open Access

A model for predicting prognosis in patients with esophageal squamous cell carcinoma based on joint representation learning

Jun Yu, Xiaoliu Wu, Min Lv, Yuanying Zhang, Xiaomei Zhang, Jintian Li, Ming Zhu, Jianfeng Huang, Qin Zhang
Article Number: 387
Published online on: 29 October 2020

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Article Open Access

MicroRNA‑623 inhibits tumor progression and is a predictor of poor prognosis of breast cancer

Chunfeng Wang, Juan Wang, Jing Zhang, Yongxiang Li, Qinghui Sun, Feng Guo, Xiupeng An
Article Number: 386
Published online on: 29 October 2020

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Article Open Access

Halofuginone inhibits tumorigenic progression of 5‑FU‑resistant human colorectal cancer HCT‑15/FU cells by targeting miR‑132‑3p in vitro

Chen Wang, Jian-Bin Zhu, Yan-Yan Yan, Wei Zhang, Xiao-Jie Gong, Xia Wang, Xiao-Liang Wang
Article Number: 385
Published online on: 23 October 2020

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Article Open Access

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

Mohiuddin M. Taher, Ghida Dairi, Ejaz Muhammad Butt, Khalid Al‑Quthami, Hisham Al‑Khalidi, Raid A. Jastania, Tahani H. Nageeti, Neda M. Bogari, Mohammad Athar, Faisal A. Al‑Allaf, Kristoffer Valerie
Article Number: 384
Published online on: 23 October 2020

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Article Open Access

The anti‑epithelial cell adhesion molecule (EpCAM) monoclonal antibody EpMab‑16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma

Hideki Hosono, Tomokazu Ohishi, Junko Takei, Teizo Asano, Yusuke Sayama, Manabu Kawada, Mika K. Kaneko, Yukinari Kato
Article Number: 383
Published online on: 23 October 2020

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Article Open Access

Overexpression of Rhophilin Rho GTPase‑binding protein 2 promotes hepatocellular carcinoma

Bo Yuan, Wentao Bo, Xielin Feng, Yong Hu, Jiawei Zeng
Article Number: 382
Published online on: 23 October 2020

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Review Open Access

Latest evidence on immunotherapy for cholangiocarcinoma (Review)

Xurui Guo, Weizhang Shen
Article Number: 381
Published online on: 23 October 2020

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Article

Immune prognostic risk score model in acute myeloid leukemia with normal karyotype

Xiaomin Dong, Danyang Zhang, Juan Zhang, Xiaolei Chen, Yue Zhang, Yong Zhang, Xiaohuan Zhou, Tingting Chen, Hebing Zhou
Article Number: 380
Published online on: 23 October 2020

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Article

Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF‑2α

Qipeng Han, Fangzhu Han, Yisheng Fan, Bowen Lian, Jinyang Xiao, Wei Sun, Dongbing Han, Hongbo Kou, Chunyan Li, Bin Wu
Article Number: 379
Published online on: 22 October 2020

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Article Open Access

Efficacy of lapatinib combined with capecitabine in patients with HER2‑positive metastatic breast cancer in a real‑world study

Xinyu Gui, Huiping Li, Ying Yan, Ruyan Zhang
Article Number: 378
Published online on: 22 October 2020

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Article Open Access

The clinical significance of apolipoprotein L1 in head and neck squamous cell carcinoma

Feng Zhong, Hui-Ping Lu, Gang Chen, Yi-Wu Dang, Xiao-Guohui Zhang, Yao Liang, Ming-Xuan Li, Guo-Sheng Li, Xiao-Yi Chen, Yu-Xuan Yao, Yong-Ying Qin, Miao Mo, Kai-Lang Zhang, Hua Ding, Zhi-Guang Huang, Zhu-Xin Wei
Article Number: 377
Published online on: 22 October 2020

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Article Open Access

Mass spectrum analysis of membrane proteins reveals that CASK, CD36 and EPB42 are differentially expressed in pancreatic adenocarcinoma

Mingming Meng, Sanhong Liu, Chen Wang, Xinjin Gu, Enqiang Linghu, Xinying Xue
Article Number: 376
Published online on: 21 October 2020

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Article Open Access

Preoperative plus postoperative neutrophil‑lymphocyte ratio for predicting overall survival following partial hepatectomy for hepatocellular carcinoma

Meilong Wu, Shizhong Yang, Xiaobin Feng, Fei  Yu, Xiangchen Liu, Jiahong Dong
Article Number: 375
Published online on: 21 October 2020

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Article Open Access

Genipin enhances the antitumor effect of elesclomol in A549 lung cancer cells by blocking uncoupling protein‑2 and stimulating reactive oxygen species production

Jin Hee Lee, Young Seok Cho, Kyung-Ho Jung, Jin Won Park, Kyung-Han Lee
Article Number: 374
Published online on: 21 October 2020

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Article Open Access

Identification and preservation of stained non‑sentinel lymph nodes in breast cancer

Xiaoyan Li, Sisi Chen, Yi Duan, Hanyin Guo, Liyu Jiang, Xiaoli Kong, Tingting Ma, Qifeng Yang
Article Number: 373
Published online on: 21 October 2020

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Article Open Access

CLC-3 and SOX2 regulate the cell cycle in DU145 cells

Jiahong Chen, Fang Wang, Yuli Lu, Shangqi Yang, Xueqin Chen, Youwei Huang, Xi Lin
Article Number: 372
Published online on: 21 October 2020

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Article Open Access

Microarray analysis of aberrant microRNA expression patterns in spinal cord gliomas of different grades

Tian An, Xin-Qing Zhang, Yu-Fei Liu, Juan Lian, Yan-Xiang Wu, Bo-Han Lv, Cong Liang, Chun-You Chen, Qi-Shuai Yu, Meng-Hua Ma, Yin-Qian Wang, Guang-Jian Jiang, Tao Fan
Article Number: 371
Published online on: 21 October 2020

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Article Open Access

Downregulation of microRNA‑605 indicates poor prognosis and promotes the progression of osteosarcoma

Xiuling Yi, Chunlei Liu
Article Number: 370
Published online on: 19 October 2020

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Article

Suppression of MKL1 promotes adipocytic differentiation and reduces the proliferation of myxoid liposarcoma cells

Yohei Kamikawa, Kento Yokota, Kosuke Oikawa, Fuyuki Sato, Yasuteru Muragaki
Article Number: 369
Published online on: 19 October 2020

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Article

Aberrantly upregulated FAM83H‑AS1 facilitates malignant progression of esophageal squamous cell carcinoma

Lijia Bu, Rong Wang, Pingping Liu, Jie Da
Article Number: 368
Published online on: 19 October 2020

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Article Open Access

MicroRNA‑1236‑3p inhibits human osteosarcoma growth

Jiarui Li, Junxin Chen, Zhijun Hu, Wenbin Xu
Article Number: 367
Published online on: 15 October 2020

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Article Open Access

Comprehensive analysis of prognostic immune‑related genes associated with the tumor microenvironment of pancreatic ductal adenocarcinoma

Shibai Yan, Juntao Fang, Yuanqiang Zhu, Yong Xie, Feng Fang
Article Number: 366
Published online on: 15 October 2020

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Article Open Access

TIPE1 impairs ovarian tumor growth by promoting caspase-dependent apoptosis

Tingting Li, Lei Jia, Yu Deng, Bo Wang, Song Quan
Article Number: 365
Published online on: 15 October 2020

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Correction Open Access

[Erratum] Identification of UBE2T as an independent prognostic biomarker for gallbladder cancer

Xuan Zhu, Tao Li, Xing Niu, Lijie Chen, Chunlin Ge
Article Number: 364
Published online on: 15 October 2020

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Article Open Access

Mechanism of intrinsic resistance of lung squamous cell carcinoma to epithelial growth factor receptor‑tyrosine kinase inhibitors revealed by high‑throughput RNA interference screening

Lixia Ju, Zhiyi Dong, Juan Yang, Minghua Li
Article Number: 363
Published online on: 15 October 2020

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Article Open Access

Bex1 significantly contributes to the proliferation and invasiveness of malignant tumor cells

Takefumi Doi, Hiroyuki Ogawa, Yugo Tanaka, Yoshitake Hayashi, Yoshimasa Maniwa
Article Number: 362
Published online on: 14 October 2020

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Article Open Access

RNA interference‑mediated downregulation of phospholipid scramblase 1 expression in primary liver cancer in vitro

Liang Gui, Ying-Wei Zhu, Qiang Xu, Ju-Ju Huang, Ping Hua, Gao-Jue Wu, Jian Lu, Jing-Bin Ni, Hong Tang, Li-Li Zhang
Article Number: 361
Published online on: 14 October 2020

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Article Open Access

Interaction between regulatory T cells and mast cells via IL‑9 and TGF‑β production

Yi-Bin Zhao, Shao-Hui Yang, Jie Shen, Ke Deng, Qi Li, Yu Wang, Wei Cui, Hua Ye
Article Number: 360
Published online on: 14 October 2020

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Article Open Access

MicroRNA‑454‑3p inhibits cell proliferation and invasion in esophageal cancer by targeting insulin‑like growth factor 2 mRNA‑binding protein 1

Aiting Yan, Cuizhu Wang, Liangfeng Zheng, Jiebo Zhou, Yan Zhang
Article Number: 359
Published online on: 14 October 2020

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Article Open Access

Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells

Chunyu Liu, Fei Wang, Bin Wang, Ting Wu, Yue Wang, Wenbo Huo, Shuxia Zhang, Ying Su, Jinming Liu, Yumeng Liu, Jinghua Yu
Article Number: 358
Published online on: 14 October 2020

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Article Open Access

Genome‑wide methylation profiles in monozygotic twins with discordance for ovarian carcinoma

Ozge Sukruoglu Erdogan, Seref Bugra Tuncer, Seda Kilic, Demet Akdeniz Odemis, Gozde Kuru Turkcan, Betul Celik, Mukaddes Avsar, Hulya Yazici
Article Number: 357
Published online on: 14 October 2020

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Article Open Access

Coiled‑coil domain‑containing 68 promotes non‑small cell lung cancer cell proliferation in vitro

Tao Hua, Jie Ding, Jialing Xu, Yu Fan, Zejie Liu, Juanwen Lian
Article Number: 356
Published online on: 14 October 2020

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Article Open Access

Long non‑coding RNA MIAT promotes gastric cancer proliferation and metastasis via modulating the miR‑331‑3p/RAB5B pathway

Xiao-Mei Li, Yan-Yan Jiao, Bao-Hong Luan, Hong-Xia Wu, Rong-Rong Wang, Jie Zhong
Article Number: 355
Published online on: 13 October 2020

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Article Open Access

Establishment of a type II insulin‑like growth factor receptor gene site‑integrated SKBR3 cell line using CRISPR/Cas9

Xinyu Ma, Ru Cao, Haiyan Xiao, Zhongwei Cao
Article Number: 354
Published online on: 11 October 2020

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Article Open Access

MicroRNA‑155‑5p inhibits the invasion and migration of prostate cancer cells by targeting SPOCK1

Lin-Ya Yao, Jun Ma, Xue-Ming Zeng, Jun Ou‑yang
Article Number: 353
Published online on: 11 October 2020

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Article Open Access

Macrophages in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis

Sayaka Kobayashi, Masanao Saio, Misa Fujimori, Junko Hirato, Tetsunari Oyama, Toshio Fukuda
Article Number: 352
Published online on: 11 October 2020

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Article Open Access

Novel canine isocitrate dehydrogenase 1 mutation Y208C attenuates dimerization ability

Shota Kawakami, Masaki Michishita, Motoharu Sakaue, Masami Morimatsu, Mitsuki Uemura, Nobuaki Kashiwagi, Marika Maeda, Yukino Machida, Daigo Azakami, Ai S. Egusa, Eri Onozawa, Katsumi Ishioka, Masami Watanabe, Yoshikazu Tanaka, Toshinori Omi, Kazuhiko Ochiai
Article Number: 351
Published online on: 11 October 2020

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Article Open Access

Usefulness of serum miR‑1246/miR‑106b ratio in patients with esophageal squamous cell carcinoma

Isamu Hoshino, Fumitaka Ishige, Yosuke Iwatate, Hisashi Gunji, Fumiaki Shiratori, Naoki Kuwayama, Yoshihiro Nabeya, Nobuyoshi Takeshita, Hisahiro Matsubara
Article Number: 350
Published online on: 10 October 2020

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Article

Expression of the epigenetic H3K27me3 modifier genes KDM6A and EZH2 in patients with upper tract urothelial carcinoma

Yue Wang, Jin-Xia Zhang, Shu-Fang Wang, Yu Zhang, Hui-Ying He
Article Number: 349
Published online on: 10 October 2020

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Article Open Access

Kinesin family member 3A inhibits the carcinogenesis of non‑small cell lung cancer and prolongs survival

Yie Yang, Xiao Liu, Rui Li, Mengyu Zhang, Hong Wang, Yiqing Qu
Article Number: 348
Published online on: 10 October 2020

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Article Open Access

Low PTEN expression and overexpression of phosphorylated AktSer473 and AktThr308 are associated with poor overall survival in upper tract urothelial carcinoma

Wen-Hui Weng, Kai-Jie Yu, Liang-Chen Li, Yeu-Jye Pang, Ying-Tzu Chen, See-Tong Pang, Cheng-Keng Chuang
Article Number: 347
Published online on: 09 October 2020

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Article Open Access

Identification of AK4 as a novel therapeutic target for serous ovarian cancer

Minmin Huang, Xinlei Qin, Yuwei Wang, Furong Mao
Article Number: 346
Published online on: 08 October 2020

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Case Report Open Access

Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report

Xing Yu, Yong Wang, Qiuping Xie, Haichao Yan, Qunzi Zhao, Cheng Xiang, Maolin Zhang, Jin-Fan Li, Ping Wang
Article Number: 345
Published online on: 08 October 2020

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Article Open Access

Efficacy and safety of nanosomal docetaxel lipid suspension‑based chemotherapy in squamous cell carcinoma of the head and neck: A multicenter retrospective study

Saroj Kumar Das Majumdar, Sundaram Subramanian, Ghanashyam Biswas, Nisarg Joshi, Mujtaba A. Khan, Imran Ahmad
Article Number: 344
Published online on: 08 October 2020

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Case Report

Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review

Moonsik Kim, Jiyeon An, Sun Och Yoon, Seung Hyun Yong, Jin  Seok Kim, Woo Ick Yang, Ah Young Leem
Article Number: 343
Published online on: 08 October 2020

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Review Open Access

Association between the gut microbiota and patient responses to cancer immune checkpoint inhibitors (Review)

Jian Wang, Hong-Ru Yang, Dai-Jie Wang, Xing-Xia Wang
Article Number: 342
Published online on: 08 October 2020

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Article Open Access

Tumour stem cell markers CD133 and CD44 are useful prognostic factors after surgical resection of pancreatic neuroendocrine tumours

Zhonghai Sun, Dezhi Li, Hongmei Wu, Baohua Hou
Article Number: 341
Published online on: 08 October 2020

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Article Open Access

Effect of TTLL12 on tubulin tyrosine nitration as a novel target for screening anticancer drugs in vitro

Lingli Xue, Yan Zeng, Chuan Fang, Wei Cheng, Yadong Li
Article Number: 340
Published online on: 08 October 2020

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Article Open Access

miR‑451a suppression of IL‑6R can inhibit proliferation and increase apoptosis through the JAK2/STAT3 pathway in multiple myeloma

Ling Zhong, Zhuyu Xu, Xin Jin, Yuan He, Jianbo Zhang, Tao Jiang, Jiao Chen
Article Number: 339
Published online on: 08 October 2020

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Article Open Access

Genome‑wide analysis of microRNA to evaluate prognostic markers in isolated cancer glands and surrounding stroma in high‑grade serous ovarian carcinoma

Chie Sato, Mitsumasa Osakabe, Takayuki Nagasawa, Hiromu  Suzuki, Hiroaki Itamochi, Tsukasa Baba, Tamotsu Sugai
Article Number: 338
Published online on: 08 October 2020

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Case Report Open Access

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Identification of biomarkers predicting the chemotherapeutic outcomes of capecitabine and oxaliplatin in patients with gastric cancer

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Linalool inhibits 22Rv1 prostate cancer cell proliferation and induces apoptosis

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mRNA expression and DNA methylation analysis of the inhibitory mechanism of H2O2 on the proliferation of A549 cells

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miR‑1301‑3p promotes the proliferation and migration of lung cancer cells via direct repression of polymerase I and transcript release factor

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Long non‑coding RNA B4GALT1‑Antisense RNA 1/microRNA‑30e/SRY‑box transcription factor 9 signaling axis contributes to non‑small cell lung cancer cell growth

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Chronic exposure to the gibberellin derivative GA‑13315 sensitizes breast cancer MCF‑7 cells but not colon cancer HCT116 cells to irinotecan

Xianliang Cheng, Guohui Wang, Yuan Liao, Jiao Mo, Chen Qing
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Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells

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Celecoxib upregulates ULBP‑1 expression in lung cancer cells via the JNK/PI3K signaling pathway and increases susceptibility to natural killer cell cytotoxicity

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Serpin peptidase inhibitor clade A member 1‑overexpression in gastric cancer promotes tumor progression in vitro and is associated with poor prognosis

Longchang Jiang, Liangbiao George Hu
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MicroRNA‑1297 downregulation inhibits breast cancer cell epithelial‑mesenchymal transition and proliferation in a FA2H‑dependent manner

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CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

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[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

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LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

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[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

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Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

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Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
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[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report

Initial chemotherapy decreases transfusion dependence and enables definitive therapy in metastatic thymoma complicated by pure red cell aplasia: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Shinichi Ochi, Ryo Miyata, Masatsugu Hamaji, Sayaka Ando, Maiko Takeda, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 354
Published online on: 16 June 2026

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Article Open Access

Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie
Article Number: 353
Published online on: 16 June 2026

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Article

Circulating miRNA‑30a is associated with favorable therapeutic outcome in patients with gastric cancer treated with neoadjuvant chemotherapy

Vasileia Kokala‑dimitropoulou, Alexandros Mitrousias, Athanasios Tsiatouras, Aigli Vakrakou, Pantelis T. Antonakis, Manousos M. Konstantoulakis
Article Number: 352
Published online on: 16 June 2026

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Case Report Open Access

Salvage robotic‑assisted subtotal esophagectomy after chemoradiotherapy for unresectable locally advanced esophageal sarcoma: A case report

Masaaki Yamamoto, Atsushi Takeno, Kiyoshi Mori, Yumiko Hirose, Shinji Tokuyama, Yuki Matsui, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Takeshi Kato, Koji Takami, Motohiro Hirao
Article Number: 351
Published online on: 16 June 2026

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Article Open Access

A prognostic senescence‑related long non‑coding RNA signature identifies cold and hot tumors of stomach adenocarcinoma

Chenxi He, Fanting Kong, Baojuan Han, Litao Lv, Xiaoling Wang, Xiangguang Kong, Qingjiao Zeng, Peipei Zhou
Article Number: 350
Published online on: 16 June 2026

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Article Open Access

Double vs. single autologous stem cell transplantation in patients with multiple myeloma and high‑risk factors: A systematic review and meta‑analysis

Sibei Qin, Yusi Liu, Peng Zhang, Qionglin Zhou, Xiayan Xu, Danbo Liu, Fang Du, Jiao Chen, Lingyun Zhou, Weiling Cao, Haifei Chen
Article Number: 349
Published online on: 16 June 2026

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Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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