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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2020 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

7‑dehydrocholesterol suppresses melanoma cell proliferation and invasion via Akt1/NF‑κB signaling

Jia Liu, Feiliang Zhong, Lei Cao, Ruiying Zhu, Junze Qu, Lin Yang, Tingting Chen, Yunlong Hu, Ying Wang, Mingdong Yao, Wenhai Xiao, Chun Li, Bo Li, Yingjin Yuan
Article Number: 398
Published online on: 29 October 2020

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Article Open Access

Immune cell infiltration and cytokine secretion analysis reveal a non-inflammatory microenvironment of medulloblastoma

Shuo Diao, Chunyu Gu, Hongwei Zhang, Chunjiang Yu
Article Number: 397
Published online on: 29 October 2020

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Review Open Access

Early palliative care of non‑small cell lung cancer in the context of immunotherapy (Review)

Małgorzata Pieniążek, Piotr Pawlak, Barbara Radecka
Article Number: 396
Published online on: 29 October 2020

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Article Open Access

Immunohistochemical expression of insulin‑like growth factor‑1Ec in primary endometrial carcinoma: Association with PTEN, p53 and survivin expression

Aggelis Stavropoulos, Michail Varras, Anastassios Philippou, Thivi Vasilakaki, Viktoria-Konstantina Varra, Fani-Niki Varra, Aikaterini Tsavari, Andreas C. Lazaris, Michael Koutsilieris
Article Number: 395
Published online on: 29 October 2020

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Article Open Access

Involvement of the Wnt/β‑Catenin signaling pathway in the heterogenous nuclear ribonucleoprotein K‑driven inhibition of proliferation and migration in head and neck squamous cell carcinoma

Hongfei Liu, Xiaohong Chen, Xingjiu Yang, Mengyuan Li, Wenlong Zhang, Guoxin Zhang, Xiangwen Zhan, Lin Cao, Weisha Li, Zhigang Huang, Ran Gao
Article Number: 394
Published online on: 29 October 2020

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Article

Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction

Kazuya Nishii, Kadoaki Ohashi, Tomoki Tamura, Kiichiro Ninomiya, Takehiro  Matsubara, Satoru Senoo, Hirohisa Kano, Hiromi Watanabe, Naohiro  Oda, Go Makimoto, Hisao Higo, Yuka Kato, Takashi Ninomiya, Toshio  Kubo, Hiromasa Yamamoto, Shuta Tomida, Katsuyuki Hotta, Masahiro  Tabata, Shinichi Toyooka, Yoshinobu Maeda, Katsuyuki Kiura
Article Number: 393
Published online on: 29 October 2020

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Article

Expression of TRPC1 and SBEM protein in breast cancer tissue and its relationship with clinicopathological features and prognosis of patients

Yongqing Zhang, Xiaoqin Lun, Weiling Guo
Article Number: 392
Published online on: 29 October 2020

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Article Open Access

Thiostrepton and miR‑216b synergistically promote osteosarcoma cell cytotoxicity and apoptosis by targeting FoxM1

Xiaobing Cai, Wenyu Xiao, Juexin Shen, Hui Lian, Yi Lu, Xianmiao Liu, Jisheng Gu
Article Number: 391
Published online on: 29 October 2020

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Article Open Access

Downregulated microRNA‑140‑5p expression regulates apoptosis, migration and invasion of lung cancer cells by targeting zinc finger protein 800 Retraction in /10.3892/ol.2024.14727

Enqing Zhuo, Changqing Cai, Wenzhe Liu, Kunsong Li, Wenzhen Zhao
Article Number: 390
Published online on: 29 October 2020

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Article Open Access

Neurensin‑2 promotes proliferation, invasion and migration of colorectal cancer cells via interaction with SOX12

Gang Wang, Kai Yang
Article Number: 389
Published online on: 29 October 2020

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Article Open Access

Hypoxia-induced circular RNA hsa_circ_0008450 accelerates hepatocellular cancer progression via the miR-431/AKAP1 axis

Qiajun Du, Jie Han, Shan Gao, Shangdi Zhang, Yunyan Pan
Article Number: 388
Published online on: 29 October 2020

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Article Open Access

A model for predicting prognosis in patients with esophageal squamous cell carcinoma based on joint representation learning

Jun Yu, Xiaoliu Wu, Min Lv, Yuanying Zhang, Xiaomei Zhang, Jintian Li, Ming Zhu, Jianfeng Huang, Qin Zhang
Article Number: 387
Published online on: 29 October 2020

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Article Open Access

MicroRNA‑623 inhibits tumor progression and is a predictor of poor prognosis of breast cancer

Chunfeng Wang, Juan Wang, Jing Zhang, Yongxiang Li, Qinghui Sun, Feng Guo, Xiupeng An
Article Number: 386
Published online on: 29 October 2020

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Article Open Access

Halofuginone inhibits tumorigenic progression of 5‑FU‑resistant human colorectal cancer HCT‑15/FU cells by targeting miR‑132‑3p in vitro

Chen Wang, Jian-Bin Zhu, Yan-Yan Yan, Wei Zhang, Xiao-Jie Gong, Xia Wang, Xiao-Liang Wang
Article Number: 385
Published online on: 23 October 2020

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Article Open Access

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

Mohiuddin M. Taher, Ghida Dairi, Ejaz Muhammad Butt, Khalid Al‑Quthami, Hisham Al‑Khalidi, Raid A. Jastania, Tahani H. Nageeti, Neda M. Bogari, Mohammad Athar, Faisal A. Al‑Allaf, Kristoffer Valerie
Article Number: 384
Published online on: 23 October 2020

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Article Open Access

The anti‑epithelial cell adhesion molecule (EpCAM) monoclonal antibody EpMab‑16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma

Hideki Hosono, Tomokazu Ohishi, Junko Takei, Teizo Asano, Yusuke Sayama, Manabu Kawada, Mika K. Kaneko, Yukinari Kato
Article Number: 383
Published online on: 23 October 2020

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Article Open Access

Overexpression of Rhophilin Rho GTPase‑binding protein 2 promotes hepatocellular carcinoma

Bo Yuan, Wentao Bo, Xielin Feng, Yong Hu, Jiawei Zeng
Article Number: 382
Published online on: 23 October 2020

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Review Open Access

Latest evidence on immunotherapy for cholangiocarcinoma (Review)

Xurui Guo, Weizhang Shen
Article Number: 381
Published online on: 23 October 2020

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Article

Immune prognostic risk score model in acute myeloid leukemia with normal karyotype

Xiaomin Dong, Danyang Zhang, Juan Zhang, Xiaolei Chen, Yue Zhang, Yong Zhang, Xiaohuan Zhou, Tingting Chen, Hebing Zhou
Article Number: 380
Published online on: 23 October 2020

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Article

Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF‑2α

Qipeng Han, Fangzhu Han, Yisheng Fan, Bowen Lian, Jinyang Xiao, Wei Sun, Dongbing Han, Hongbo Kou, Chunyan Li, Bin Wu
Article Number: 379
Published online on: 22 October 2020

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Article Open Access

Efficacy of lapatinib combined with capecitabine in patients with HER2‑positive metastatic breast cancer in a real‑world study

Xinyu Gui, Huiping Li, Ying Yan, Ruyan Zhang
Article Number: 378
Published online on: 22 October 2020

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Article Open Access

The clinical significance of apolipoprotein L1 in head and neck squamous cell carcinoma

Feng Zhong, Hui-Ping Lu, Gang Chen, Yi-Wu Dang, Xiao-Guohui Zhang, Yao Liang, Ming-Xuan Li, Guo-Sheng Li, Xiao-Yi Chen, Yu-Xuan Yao, Yong-Ying Qin, Miao Mo, Kai-Lang Zhang, Hua Ding, Zhi-Guang Huang, Zhu-Xin Wei
Article Number: 377
Published online on: 22 October 2020

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Article Open Access

Mass spectrum analysis of membrane proteins reveals that CASK, CD36 and EPB42 are differentially expressed in pancreatic adenocarcinoma

Mingming Meng, Sanhong Liu, Chen Wang, Xinjin Gu, Enqiang Linghu, Xinying Xue
Article Number: 376
Published online on: 21 October 2020

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Article Open Access

Preoperative plus postoperative neutrophil‑lymphocyte ratio for predicting overall survival following partial hepatectomy for hepatocellular carcinoma

Meilong Wu, Shizhong Yang, Xiaobin Feng, Fei  Yu, Xiangchen Liu, Jiahong Dong
Article Number: 375
Published online on: 21 October 2020

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Article Open Access

Genipin enhances the antitumor effect of elesclomol in A549 lung cancer cells by blocking uncoupling protein‑2 and stimulating reactive oxygen species production

Jin Hee Lee, Young Seok Cho, Kyung-Ho Jung, Jin Won Park, Kyung-Han Lee
Article Number: 374
Published online on: 21 October 2020

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Article Open Access

Identification and preservation of stained non‑sentinel lymph nodes in breast cancer

Xiaoyan Li, Sisi Chen, Yi Duan, Hanyin Guo, Liyu Jiang, Xiaoli Kong, Tingting Ma, Qifeng Yang
Article Number: 373
Published online on: 21 October 2020

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Article Open Access

CLC-3 and SOX2 regulate the cell cycle in DU145 cells

Jiahong Chen, Fang Wang, Yuli Lu, Shangqi Yang, Xueqin Chen, Youwei Huang, Xi Lin
Article Number: 372
Published online on: 21 October 2020

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Article Open Access

Microarray analysis of aberrant microRNA expression patterns in spinal cord gliomas of different grades

Tian An, Xin-Qing Zhang, Yu-Fei Liu, Juan Lian, Yan-Xiang Wu, Bo-Han Lv, Cong Liang, Chun-You Chen, Qi-Shuai Yu, Meng-Hua Ma, Yin-Qian Wang, Guang-Jian Jiang, Tao Fan
Article Number: 371
Published online on: 21 October 2020

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Article Open Access

Downregulation of microRNA‑605 indicates poor prognosis and promotes the progression of osteosarcoma

Xiuling Yi, Chunlei Liu
Article Number: 370
Published online on: 19 October 2020

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Article

Suppression of MKL1 promotes adipocytic differentiation and reduces the proliferation of myxoid liposarcoma cells

Yohei Kamikawa, Kento Yokota, Kosuke Oikawa, Fuyuki Sato, Yasuteru Muragaki
Article Number: 369
Published online on: 19 October 2020

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Article

Aberrantly upregulated FAM83H‑AS1 facilitates malignant progression of esophageal squamous cell carcinoma

Lijia Bu, Rong Wang, Pingping Liu, Jie Da
Article Number: 368
Published online on: 19 October 2020

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Article Open Access

MicroRNA‑1236‑3p inhibits human osteosarcoma growth

Jiarui Li, Junxin Chen, Zhijun Hu, Wenbin Xu
Article Number: 367
Published online on: 15 October 2020

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Article Open Access

Comprehensive analysis of prognostic immune‑related genes associated with the tumor microenvironment of pancreatic ductal adenocarcinoma

Shibai Yan, Juntao Fang, Yuanqiang Zhu, Yong Xie, Feng Fang
Article Number: 366
Published online on: 15 October 2020

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Article Open Access

TIPE1 impairs ovarian tumor growth by promoting caspase-dependent apoptosis

Tingting Li, Lei Jia, Yu Deng, Bo Wang, Song Quan
Article Number: 365
Published online on: 15 October 2020

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Correction Open Access

[Erratum] Identification of UBE2T as an independent prognostic biomarker for gallbladder cancer

Xuan Zhu, Tao Li, Xing Niu, Lijie Chen, Chunlin Ge
Article Number: 364
Published online on: 15 October 2020

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Article Open Access

Mechanism of intrinsic resistance of lung squamous cell carcinoma to epithelial growth factor receptor‑tyrosine kinase inhibitors revealed by high‑throughput RNA interference screening

Lixia Ju, Zhiyi Dong, Juan Yang, Minghua Li
Article Number: 363
Published online on: 15 October 2020

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Article Open Access

Bex1 significantly contributes to the proliferation and invasiveness of malignant tumor cells

Takefumi Doi, Hiroyuki Ogawa, Yugo Tanaka, Yoshitake Hayashi, Yoshimasa Maniwa
Article Number: 362
Published online on: 14 October 2020

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Article Open Access

RNA interference‑mediated downregulation of phospholipid scramblase 1 expression in primary liver cancer in vitro

Liang Gui, Ying-Wei Zhu, Qiang Xu, Ju-Ju Huang, Ping Hua, Gao-Jue Wu, Jian Lu, Jing-Bin Ni, Hong Tang, Li-Li Zhang
Article Number: 361
Published online on: 14 October 2020

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Article Open Access

Interaction between regulatory T cells and mast cells via IL‑9 and TGF‑β production

Yi-Bin Zhao, Shao-Hui Yang, Jie Shen, Ke Deng, Qi Li, Yu Wang, Wei Cui, Hua Ye
Article Number: 360
Published online on: 14 October 2020

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Article Open Access

MicroRNA‑454‑3p inhibits cell proliferation and invasion in esophageal cancer by targeting insulin‑like growth factor 2 mRNA‑binding protein 1

Aiting Yan, Cuizhu Wang, Liangfeng Zheng, Jiebo Zhou, Yan Zhang
Article Number: 359
Published online on: 14 October 2020

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Article Open Access

Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells

Chunyu Liu, Fei Wang, Bin Wang, Ting Wu, Yue Wang, Wenbo Huo, Shuxia Zhang, Ying Su, Jinming Liu, Yumeng Liu, Jinghua Yu
Article Number: 358
Published online on: 14 October 2020

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Article Open Access

Genome‑wide methylation profiles in monozygotic twins with discordance for ovarian carcinoma

Ozge Sukruoglu Erdogan, Seref Bugra Tuncer, Seda Kilic, Demet Akdeniz Odemis, Gozde Kuru Turkcan, Betul Celik, Mukaddes Avsar, Hulya Yazici
Article Number: 357
Published online on: 14 October 2020

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Article Open Access

Coiled‑coil domain‑containing 68 promotes non‑small cell lung cancer cell proliferation in vitro

Tao Hua, Jie Ding, Jialing Xu, Yu Fan, Zejie Liu, Juanwen Lian
Article Number: 356
Published online on: 14 October 2020

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Article Open Access

Long non‑coding RNA MIAT promotes gastric cancer proliferation and metastasis via modulating the miR‑331‑3p/RAB5B pathway

Xiao-Mei Li, Yan-Yan Jiao, Bao-Hong Luan, Hong-Xia Wu, Rong-Rong Wang, Jie Zhong
Article Number: 355
Published online on: 13 October 2020

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Article Open Access

Establishment of a type II insulin‑like growth factor receptor gene site‑integrated SKBR3 cell line using CRISPR/Cas9

Xinyu Ma, Ru Cao, Haiyan Xiao, Zhongwei Cao
Article Number: 354
Published online on: 11 October 2020

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Article Open Access

MicroRNA‑155‑5p inhibits the invasion and migration of prostate cancer cells by targeting SPOCK1

Lin-Ya Yao, Jun Ma, Xue-Ming Zeng, Jun Ou‑yang
Article Number: 353
Published online on: 11 October 2020

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Article Open Access

Macrophages in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis

Sayaka Kobayashi, Masanao Saio, Misa Fujimori, Junko Hirato, Tetsunari Oyama, Toshio Fukuda
Article Number: 352
Published online on: 11 October 2020

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Article Open Access

Novel canine isocitrate dehydrogenase 1 mutation Y208C attenuates dimerization ability

Shota Kawakami, Masaki Michishita, Motoharu Sakaue, Masami Morimatsu, Mitsuki Uemura, Nobuaki Kashiwagi, Marika Maeda, Yukino Machida, Daigo Azakami, Ai S. Egusa, Eri Onozawa, Katsumi Ishioka, Masami Watanabe, Yoshikazu Tanaka, Toshinori Omi, Kazuhiko Ochiai
Article Number: 351
Published online on: 11 October 2020

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Article Open Access

Usefulness of serum miR‑1246/miR‑106b ratio in patients with esophageal squamous cell carcinoma

Isamu Hoshino, Fumitaka Ishige, Yosuke Iwatate, Hisashi Gunji, Fumiaki Shiratori, Naoki Kuwayama, Yoshihiro Nabeya, Nobuyoshi Takeshita, Hisahiro Matsubara
Article Number: 350
Published online on: 10 October 2020

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Article

Expression of the epigenetic H3K27me3 modifier genes KDM6A and EZH2 in patients with upper tract urothelial carcinoma

Yue Wang, Jin-Xia Zhang, Shu-Fang Wang, Yu Zhang, Hui-Ying He
Article Number: 349
Published online on: 10 October 2020

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Article Open Access

Kinesin family member 3A inhibits the carcinogenesis of non‑small cell lung cancer and prolongs survival

Yie Yang, Xiao Liu, Rui Li, Mengyu Zhang, Hong Wang, Yiqing Qu
Article Number: 348
Published online on: 10 October 2020

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Article Open Access

Low PTEN expression and overexpression of phosphorylated AktSer473 and AktThr308 are associated with poor overall survival in upper tract urothelial carcinoma

Wen-Hui Weng, Kai-Jie Yu, Liang-Chen Li, Yeu-Jye Pang, Ying-Tzu Chen, See-Tong Pang, Cheng-Keng Chuang
Article Number: 347
Published online on: 09 October 2020

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Article Open Access

Identification of AK4 as a novel therapeutic target for serous ovarian cancer

Minmin Huang, Xinlei Qin, Yuwei Wang, Furong Mao
Article Number: 346
Published online on: 08 October 2020

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Case Report Open Access

Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report

Xing Yu, Yong Wang, Qiuping Xie, Haichao Yan, Qunzi Zhao, Cheng Xiang, Maolin Zhang, Jin-Fan Li, Ping Wang
Article Number: 345
Published online on: 08 October 2020

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Article Open Access

Efficacy and safety of nanosomal docetaxel lipid suspension‑based chemotherapy in squamous cell carcinoma of the head and neck: A multicenter retrospective study

Saroj Kumar Das Majumdar, Sundaram Subramanian, Ghanashyam Biswas, Nisarg Joshi, Mujtaba A. Khan, Imran Ahmad
Article Number: 344
Published online on: 08 October 2020

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Case Report

Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review

Moonsik Kim, Jiyeon An, Sun Och Yoon, Seung Hyun Yong, Jin  Seok Kim, Woo Ick Yang, Ah Young Leem
Article Number: 343
Published online on: 08 October 2020

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Review Open Access

Association between the gut microbiota and patient responses to cancer immune checkpoint inhibitors (Review)

Jian Wang, Hong-Ru Yang, Dai-Jie Wang, Xing-Xia Wang
Article Number: 342
Published online on: 08 October 2020

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Article Open Access

Tumour stem cell markers CD133 and CD44 are useful prognostic factors after surgical resection of pancreatic neuroendocrine tumours

Zhonghai Sun, Dezhi Li, Hongmei Wu, Baohua Hou
Article Number: 341
Published online on: 08 October 2020

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Article Open Access

Effect of TTLL12 on tubulin tyrosine nitration as a novel target for screening anticancer drugs in vitro

Lingli Xue, Yan Zeng, Chuan Fang, Wei Cheng, Yadong Li
Article Number: 340
Published online on: 08 October 2020

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Article Open Access

miR‑451a suppression of IL‑6R can inhibit proliferation and increase apoptosis through the JAK2/STAT3 pathway in multiple myeloma

Ling Zhong, Zhuyu Xu, Xin Jin, Yuan He, Jianbo Zhang, Tao Jiang, Jiao Chen
Article Number: 339
Published online on: 08 October 2020

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Article Open Access

Genome‑wide analysis of microRNA to evaluate prognostic markers in isolated cancer glands and surrounding stroma in high‑grade serous ovarian carcinoma

Chie Sato, Mitsumasa Osakabe, Takayuki Nagasawa, Hiromu  Suzuki, Hiroaki Itamochi, Tsukasa Baba, Tamotsu Sugai
Article Number: 338
Published online on: 08 October 2020

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Case Report Open Access

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Trefoil factor 1 and gastrokine 2 inhibit Helicobacter pylori‑induced proliferation and inflammation in gastric cardia and distal carcinogenesis

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Endothelial transdifferentiation of human HGC‑27 gastric cancer cells in vitro

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Long non‑coding RNA expression profiles and related regulatory networks in areca nut chewing‑induced tongue squamous cell carcinoma

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Decline in serum progastrin‑releasing peptide predicts the response of patients with small cell lung cancer to chemotherapy

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Anti‑CD206 antibody‑conjugated Fe3O4‑based PLGA nanoparticles selectively promote tumor‑associated macrophages to polarize to the pro‑inflammatory subtype

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Expression and clinical correlation of Survivin and PTEN in gastric cancer patients

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Clinical effect and safety evaluation of hydromorphone combined with sufentanil in patient‑controlled intravenous analgesia for patients with hepatocellular cancer and its effect on serum immune factors

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Small molecule 2,3‑DCPE induces S phase arrest by activating the ATM/ATR‑Chk1‑Cdc25A signaling pathway in DLD‑1 colon cancer cells

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Forkhead box P3 promotes breast cancer cell apoptosis by regulating programmed cell death 4 expression

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Identification of biomarkers predicting the chemotherapeutic outcomes of capecitabine and oxaliplatin in patients with gastric cancer

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Linalool inhibits 22Rv1 prostate cancer cell proliferation and induces apoptosis

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mRNA expression and DNA methylation analysis of the inhibitory mechanism of H2O2 on the proliferation of A549 cells

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Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection Retraction in /10.3892/ol.2025.15362

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miR‑1301‑3p promotes the proliferation and migration of lung cancer cells via direct repression of polymerase I and transcript release factor

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Long non‑coding RNA B4GALT1‑Antisense RNA 1/microRNA‑30e/SRY‑box transcription factor 9 signaling axis contributes to non‑small cell lung cancer cell growth

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Chronic exposure to the gibberellin derivative GA‑13315 sensitizes breast cancer MCF‑7 cells but not colon cancer HCT116 cells to irinotecan

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Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells

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Celecoxib upregulates ULBP‑1 expression in lung cancer cells via the JNK/PI3K signaling pathway and increases susceptibility to natural killer cell cytotoxicity

Jayoung Kim, Min Hye Noh, Dae Young Hur, Bomi Kim, Yeong Seok Kim, Hyun-Kyung Lee
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Serpin peptidase inhibitor clade A member 1‑overexpression in gastric cancer promotes tumor progression in vitro and is associated with poor prognosis

Longchang Jiang, Liangbiao George Hu
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MicroRNA‑1297 downregulation inhibits breast cancer cell epithelial‑mesenchymal transition and proliferation in a FA2H‑dependent manner

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Autophagy promotes malignant migration and invasion via miR‑224‑5p/BCL2 in pancreatic mucinous cystadenocarcinoma MCC1 cells

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CiteScore Rank: Q3: #233/428 Oncology

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[Corrigendum] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

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Bingchen Li, Xinchen Tian, Qing-Qing Yu, Hongxia Cui
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Keratin gene expression signature predicts prognosis and immunotherapy efficacy in lung adenocarcinoma

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Prognostic value of nutritional and inflammatory biomarkers in patients with non‑small cell lung cancer and bone metastasis: A retrospective study

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[Retracted] Effects of FHIT gene on proliferation and apoptosis of osteosarcoma cells

Zhengfeng Xu, Jiajun Wu, Pan Cai, Xiaoxiao Zhou, Cunguo Yi, Bin Wang
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Ferroptosis regulatory networks as therapeutic sensitizers in combination therapy for hepatocellular carcinoma (Review)

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 Establishment of extrahepatic bile duct cancer organoids using suspension culture and their application in clinical drug screening

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Systems biology of Wnt signaling in glioma chemotherapy resistance: Integrating multi‑omics mechanisms and emerging therapeutic vulnerabilities (Review)

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A three‑gene signature correlated with MAPK/ERK activation characterizes acquired resistance to EGFR‑tyrosine kinase inhibitors in non‑small cell lung cancer

Changtai Qin, Wei Zhang, Dongfang Tang, Yuxi Yang, Binghui Liang, Zhiming Hu, Yuxiao Zhang, Tingjie Ye, Wei Xu
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Role of PCSK9 in hallmarks of cancer: From mechanisms to interventions (Review)

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PRR11 expression in early ER+/HER2‑low breast cancer: Association with estrogen receptor positivity and exploratory analysis of prognostic significance

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[Expression of Concern] Elevated microRNA‑125b levels predict a worse prognosis in HER2‑positive breast cancer patients  

Yanwei Luo, Xinye Wang, Weihong Niu, Heran Wang, Qiuyuan Wen, Songqing Fan, Ran Zhao, Zheng Li, Wei Xiong, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Guiyuan Li, Ming Tan, Ming Zhou
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Association between the presence of EGFR or ALK mutations and the location of primary non‑small cell lung cancer, as well as metabolic activity observed on 18F‑FDG PET/CT scans

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Advances in Helicobacter pylori-mediated oncogenic signaling pathways in gastric cancer: From pathological evolution to clinical application prospects (Review)

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Clinical and biological significance of TROY (TNFRSF19) splice variants in colorectal cancer

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[Retracted] Sirtuin 7 promotes glioma proliferation and invasion through activation of the ERK/STAT3 signaling pathway

Pengfei Mu, Kun Liu, Qingyuan Lin, Wensheng Yang, Dan Liu, Zhen Lin, Wei Shao, Tianhai Ji
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Molecular signatures of triple‑negative breast cancer cells acquiring palbociclib resistance via continuous exposure

Daichi Enomoto, Yumika Iwasa, Natsuho Irie, Haruki Ohata, Yuki Uemichi, Miyuki Mabuchi, Tadashi Shimizu, Kohji Takara
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Cell‑cycle reactivation and hepatocyte identity loss in hepatocellular carcinoma: Transcriptomic hallmarks and validation strategies (Review)

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[Expression of Concern] Fatty acids inhibit anticancer effects of 5‑fluorouracil in mouse cancer cell lines

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A nomogram prediction model for brain metastases in patients with lung adenocarcinoma 

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Survival benefits of non‑surgical triple therapy in hepatocellular carcinoma with inferior vena cava/right atrial tumor thrombus: A retrospective analysis from a multidisciplinary team

Peng Tang, Jin Li, Jiayu Duan, Xin Wang, Jin Zhou, Yu Yang, Yong Zeng
Article Number: 399
Published online on: 08 July 2026

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Article Open Access

A bioinformatics analysis of KIF transcriptomic subtyping reveals prognostic heterogeneity and differential therapeutic responses in cervical cancer

Xinyi Zhao, Jie Wu, Lan Li, Haohan Zhang, Jing Li, Hao Zhong, Yuchao Dan, Qibin Song, Hongbin Chen, Bin Xu
Article Number: 398
Published online on: 08 July 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA OIP5‑AS1 promotes the progression of esophageal cancer by regulating miR‑30a/VOPP1 expression

Jiajun Xu, Zhixi Chen, Zheng Fang, Shixiong Chen, Ying Guo, Xianfeng Liu, Kai Chen, Shengjia Chen
Article Number: 397
Published online on: 08 July 2026

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Article Open Access

FUBP3 regulates expression and alternative splicing of genes associated with cell proliferation and apoptosis in cancer cells

Lingyu Kong, Chaoxu Fu, Xuesong Li, Mingxin Chen, Xinqi Liu, Min Zhou, Tongshu Wang, Hongxin Piao
Article Number: 396
Published online on: 07 July 2026

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Article

Pan‑immune‑inflammation value as a prognostic and predictive biomarker in metastatic non‑small cell lung cancer treated with nivolumab: A real‑world study

Nedim Turan, Hacer Sahika Yildiz, Sedat Yildirim, Ezgi Turkoglu, Ugur Ozkerim, Sila Oksuz, Neslihan Buyukmurat, Hamit Bal, Heves Surmeli, Hatice Odabas
Article Number: 395
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] miR‑5590‑3p inhibits the proliferation and metastasis of renal cancer cells by targeting ROCK2 to inhibit proliferation, migration and invasion

Queling Liu, Anyi Zhu, Weiyin Gao, Fu Gui, Yan Zou, Xiaocheng Zhou, Zhengdong Hong
Article Number: 394
Published online on: 06 July 2026

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Article

Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer

Jinfen Yao, Jie Chen
Article Number: 393
Published online on: 03 July 2026

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Review Open Access

Regulatory roles of N6‑methyladenosine methylation factors in melanoma invasion and metastasis (Review)

Zhijie Xu, Wanqun Yu, Jie Liu, Xiyue Chang, Shiraz Manji Laeeqa, Zerong Xu, Qi Yang, Wanan Xiao
Article Number: 392
Published online on: 03 July 2026

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Review

Microbiota in pancreatic cancer: Roles in tumor initiation and progression (Review)

Yanjun Lou, Yiqun Fan
Article Number: 391
Published online on: 03 July 2026

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Review Open Access

Role of long non‑coding RNA HCG11 in human cancers: From molecular mechanisms to clinical applications (Review)

Qiong-Feng Tan, Bo Chen, Hai-Feng Hu, Huang Liu, Wen Huang, Wei Mu
Article Number: 390
Published online on: 03 July 2026

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Expression of Concern Open Access

[Expression of Concern] Endosialin/CD248 may be a potential therapeutic target to prevent the invasion and metastasis in osteosarcoma

Yumiko Kondo, Kanya Honoki, Shingo Kishi, Shiori Mori, Rina Fujiwara‑Tani, Shinji Tsukamoto, Hiromasa Fujii, Hiroki Kuniyasu, Yasuhito Tanaka
Article Number: 389
Published online on: 03 July 2026

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Review Open Access

Emerging roles of O‑GlcNAcylation in tumorigenesis, immunosuppression and drug resistance (Review)

Yuntong Liu, Yumo Han, Shumei Ding, Han Deng, Shiyue Li, Yingyu Zhang, Haimeng Yin, Bo You
Article Number: 388
Published online on: 02 July 2026

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Article Open Access

Efficacy and safety of immune checkpoint inhibitors combined with anti‑angiogenic agents for advanced cervical cancer: A systematic review and meta‑analysis

Hengchang Chen, Xue Yang, Yulu Qin, Wentong Xu, Mingzhu Jiao, Xinyu Lu, Yaxu Su, Fengjuan Zhou, Yong Xin
Article Number: 387
Published online on: 02 July 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin

Dong Wang, Xiaohou Wu
Article Number: 386
Published online on: 02 July 2026

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Article Open Access

Lymphocyte‑to‑C‑reactive protein ratio as a clinically feasible nutrition‑inflammation marker for predicting outcomes in patients with gastric cancer

Kai Liu, Lai Chang
Article Number: 385
Published online on: 02 July 2026

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Article Open Access

Identification and validation of aging‑related genes in patients with multiple myeloma

Huajing Liu, Senhua Song, Yingtao Wu, Yu Wang, Yueping Liu, Ying Liu
Article Number: 384
Published online on: 02 July 2026

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Retraction Open Access

[Retracted] miR‑331‑3p suppresses cell invasion and migration in colorectal carcinoma by directly targeting NRP2

Hongye Zhang, Ruiyu Wang, Mingxia Wang
Article Number: 383
Published online on: 01 July 2026

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Article Open Access

Air pollution and hepatocellular carcinoma: Integrated network toxicology, machine learning, molecular docking and multiomics analysis

Xiaorong Wang, Huihao Qin, Jing Jing, Yun Liu, Lei Guo, Hongquan Liu, Wei Zhang
Article Number: 382
Published online on: 30 June 2026

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Case Report Open Access

Cervical metastasis in breast cancer: A case report

Xinru Liu, Ke Sun, Hongming Zhu, Tonghua Du, Liyang Sheng, Bin Liu
Article Number: 381
Published online on: 30 June 2026

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Review Open Access

New and emerging strategies for targeting cancers: Challenges and opportunities (Review)

Sreenivasa R. Chinni, Arun K. Rishi, Kaladhar B. Reddy
Article Number: 380
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Article Number: 379
Published online on: 29 June 2026

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October-2026 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Article Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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