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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2020 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

7‑dehydrocholesterol suppresses melanoma cell proliferation and invasion via Akt1/NF‑κB signaling

Jia Liu, Feiliang Zhong, Lei Cao, Ruiying Zhu, Junze Qu, Lin Yang, Tingting Chen, Yunlong Hu, Ying Wang, Mingdong Yao, Wenhai Xiao, Chun Li, Bo Li, Yingjin Yuan
Article Number: 398
Published online on: 29 October 2020

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Article Open Access

Immune cell infiltration and cytokine secretion analysis reveal a non-inflammatory microenvironment of medulloblastoma

Shuo Diao, Chunyu Gu, Hongwei Zhang, Chunjiang Yu
Article Number: 397
Published online on: 29 October 2020

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Review Open Access

Early palliative care of non‑small cell lung cancer in the context of immunotherapy (Review)

Małgorzata Pieniążek, Piotr Pawlak, Barbara Radecka
Article Number: 396
Published online on: 29 October 2020

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Article Open Access

Immunohistochemical expression of insulin‑like growth factor‑1Ec in primary endometrial carcinoma: Association with PTEN, p53 and survivin expression

Aggelis Stavropoulos, Michail Varras, Anastassios Philippou, Thivi Vasilakaki, Viktoria-Konstantina Varra, Fani-Niki Varra, Aikaterini Tsavari, Andreas C. Lazaris, Michael Koutsilieris
Article Number: 395
Published online on: 29 October 2020

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Article Open Access

Involvement of the Wnt/β‑Catenin signaling pathway in the heterogenous nuclear ribonucleoprotein K‑driven inhibition of proliferation and migration in head and neck squamous cell carcinoma

Hongfei Liu, Xiaohong Chen, Xingjiu Yang, Mengyuan Li, Wenlong Zhang, Guoxin Zhang, Xiangwen Zhan, Lin Cao, Weisha Li, Zhigang Huang, Ran Gao
Article Number: 394
Published online on: 29 October 2020

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Article

Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction

Kazuya Nishii, Kadoaki Ohashi, Tomoki Tamura, Kiichiro Ninomiya, Takehiro  Matsubara, Satoru Senoo, Hirohisa Kano, Hiromi Watanabe, Naohiro  Oda, Go Makimoto, Hisao Higo, Yuka Kato, Takashi Ninomiya, Toshio  Kubo, Hiromasa Yamamoto, Shuta Tomida, Katsuyuki Hotta, Masahiro  Tabata, Shinichi Toyooka, Yoshinobu Maeda, Katsuyuki Kiura
Article Number: 393
Published online on: 29 October 2020

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Article

Expression of TRPC1 and SBEM protein in breast cancer tissue and its relationship with clinicopathological features and prognosis of patients

Yongqing Zhang, Xiaoqin Lun, Weiling Guo
Article Number: 392
Published online on: 29 October 2020

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Article Open Access

Thiostrepton and miR‑216b synergistically promote osteosarcoma cell cytotoxicity and apoptosis by targeting FoxM1

Xiaobing Cai, Wenyu Xiao, Juexin Shen, Hui Lian, Yi Lu, Xianmiao Liu, Jisheng Gu
Article Number: 391
Published online on: 29 October 2020

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Article Open Access

Downregulated microRNA‑140‑5p expression regulates apoptosis, migration and invasion of lung cancer cells by targeting zinc finger protein 800 Retraction in /10.3892/ol.2024.14727

Enqing Zhuo, Changqing Cai, Wenzhe Liu, Kunsong Li, Wenzhen Zhao
Article Number: 390
Published online on: 29 October 2020

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Article Open Access

Neurensin‑2 promotes proliferation, invasion and migration of colorectal cancer cells via interaction with SOX12

Gang Wang, Kai Yang
Article Number: 389
Published online on: 29 October 2020

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Article Open Access

Hypoxia-induced circular RNA hsa_circ_0008450 accelerates hepatocellular cancer progression via the miR-431/AKAP1 axis

Qiajun Du, Jie Han, Shan Gao, Shangdi Zhang, Yunyan Pan
Article Number: 388
Published online on: 29 October 2020

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Article Open Access

A model for predicting prognosis in patients with esophageal squamous cell carcinoma based on joint representation learning

Jun Yu, Xiaoliu Wu, Min Lv, Yuanying Zhang, Xiaomei Zhang, Jintian Li, Ming Zhu, Jianfeng Huang, Qin Zhang
Article Number: 387
Published online on: 29 October 2020

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Article Open Access

MicroRNA‑623 inhibits tumor progression and is a predictor of poor prognosis of breast cancer

Chunfeng Wang, Juan Wang, Jing Zhang, Yongxiang Li, Qinghui Sun, Feng Guo, Xiupeng An
Article Number: 386
Published online on: 29 October 2020

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Article Open Access

Halofuginone inhibits tumorigenic progression of 5‑FU‑resistant human colorectal cancer HCT‑15/FU cells by targeting miR‑132‑3p in vitro

Chen Wang, Jian-Bin Zhu, Yan-Yan Yan, Wei Zhang, Xiao-Jie Gong, Xia Wang, Xiao-Liang Wang
Article Number: 385
Published online on: 23 October 2020

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Article Open Access

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

Mohiuddin M. Taher, Ghida Dairi, Ejaz Muhammad Butt, Khalid Al‑Quthami, Hisham Al‑Khalidi, Raid A. Jastania, Tahani H. Nageeti, Neda M. Bogari, Mohammad Athar, Faisal A. Al‑Allaf, Kristoffer Valerie
Article Number: 384
Published online on: 23 October 2020

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Article Open Access

The anti‑epithelial cell adhesion molecule (EpCAM) monoclonal antibody EpMab‑16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma

Hideki Hosono, Tomokazu Ohishi, Junko Takei, Teizo Asano, Yusuke Sayama, Manabu Kawada, Mika K. Kaneko, Yukinari Kato
Article Number: 383
Published online on: 23 October 2020

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Article Open Access

Overexpression of Rhophilin Rho GTPase‑binding protein 2 promotes hepatocellular carcinoma

Bo Yuan, Wentao Bo, Xielin Feng, Yong Hu, Jiawei Zeng
Article Number: 382
Published online on: 23 October 2020

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Review Open Access

Latest evidence on immunotherapy for cholangiocarcinoma (Review)

Xurui Guo, Weizhang Shen
Article Number: 381
Published online on: 23 October 2020

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Article

Immune prognostic risk score model in acute myeloid leukemia with normal karyotype

Xiaomin Dong, Danyang Zhang, Juan Zhang, Xiaolei Chen, Yue Zhang, Yong Zhang, Xiaohuan Zhou, Tingting Chen, Hebing Zhou
Article Number: 380
Published online on: 23 October 2020

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Article

Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF‑2α

Qipeng Han, Fangzhu Han, Yisheng Fan, Bowen Lian, Jinyang Xiao, Wei Sun, Dongbing Han, Hongbo Kou, Chunyan Li, Bin Wu
Article Number: 379
Published online on: 22 October 2020

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Article Open Access

Efficacy of lapatinib combined with capecitabine in patients with HER2‑positive metastatic breast cancer in a real‑world study

Xinyu Gui, Huiping Li, Ying Yan, Ruyan Zhang
Article Number: 378
Published online on: 22 October 2020

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Article Open Access

The clinical significance of apolipoprotein L1 in head and neck squamous cell carcinoma

Feng Zhong, Hui-Ping Lu, Gang Chen, Yi-Wu Dang, Xiao-Guohui Zhang, Yao Liang, Ming-Xuan Li, Guo-Sheng Li, Xiao-Yi Chen, Yu-Xuan Yao, Yong-Ying Qin, Miao Mo, Kai-Lang Zhang, Hua Ding, Zhi-Guang Huang, Zhu-Xin Wei
Article Number: 377
Published online on: 22 October 2020

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Article Open Access

Mass spectrum analysis of membrane proteins reveals that CASK, CD36 and EPB42 are differentially expressed in pancreatic adenocarcinoma

Mingming Meng, Sanhong Liu, Chen Wang, Xinjin Gu, Enqiang Linghu, Xinying Xue
Article Number: 376
Published online on: 21 October 2020

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Article Open Access

Preoperative plus postoperative neutrophil‑lymphocyte ratio for predicting overall survival following partial hepatectomy for hepatocellular carcinoma

Meilong Wu, Shizhong Yang, Xiaobin Feng, Fei  Yu, Xiangchen Liu, Jiahong Dong
Article Number: 375
Published online on: 21 October 2020

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Article Open Access

Genipin enhances the antitumor effect of elesclomol in A549 lung cancer cells by blocking uncoupling protein‑2 and stimulating reactive oxygen species production

Jin Hee Lee, Young Seok Cho, Kyung-Ho Jung, Jin Won Park, Kyung-Han Lee
Article Number: 374
Published online on: 21 October 2020

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Article Open Access

Identification and preservation of stained non‑sentinel lymph nodes in breast cancer

Xiaoyan Li, Sisi Chen, Yi Duan, Hanyin Guo, Liyu Jiang, Xiaoli Kong, Tingting Ma, Qifeng Yang
Article Number: 373
Published online on: 21 October 2020

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Article Open Access

CLC-3 and SOX2 regulate the cell cycle in DU145 cells

Jiahong Chen, Fang Wang, Yuli Lu, Shangqi Yang, Xueqin Chen, Youwei Huang, Xi Lin
Article Number: 372
Published online on: 21 October 2020

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Article Open Access

Microarray analysis of aberrant microRNA expression patterns in spinal cord gliomas of different grades

Tian An, Xin-Qing Zhang, Yu-Fei Liu, Juan Lian, Yan-Xiang Wu, Bo-Han Lv, Cong Liang, Chun-You Chen, Qi-Shuai Yu, Meng-Hua Ma, Yin-Qian Wang, Guang-Jian Jiang, Tao Fan
Article Number: 371
Published online on: 21 October 2020

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Article Open Access

Downregulation of microRNA‑605 indicates poor prognosis and promotes the progression of osteosarcoma

Xiuling Yi, Chunlei Liu
Article Number: 370
Published online on: 19 October 2020

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Article

Suppression of MKL1 promotes adipocytic differentiation and reduces the proliferation of myxoid liposarcoma cells

Yohei Kamikawa, Kento Yokota, Kosuke Oikawa, Fuyuki Sato, Yasuteru Muragaki
Article Number: 369
Published online on: 19 October 2020

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Article

Aberrantly upregulated FAM83H‑AS1 facilitates malignant progression of esophageal squamous cell carcinoma

Lijia Bu, Rong Wang, Pingping Liu, Jie Da
Article Number: 368
Published online on: 19 October 2020

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Article Open Access

MicroRNA‑1236‑3p inhibits human osteosarcoma growth

Jiarui Li, Junxin Chen, Zhijun Hu, Wenbin Xu
Article Number: 367
Published online on: 15 October 2020

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Article Open Access

Comprehensive analysis of prognostic immune‑related genes associated with the tumor microenvironment of pancreatic ductal adenocarcinoma

Shibai Yan, Juntao Fang, Yuanqiang Zhu, Yong Xie, Feng Fang
Article Number: 366
Published online on: 15 October 2020

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Article Open Access

TIPE1 impairs ovarian tumor growth by promoting caspase-dependent apoptosis

Tingting Li, Lei Jia, Yu Deng, Song Quan, Bo Wang
Article Number: 365
Published online on: 15 October 2020

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Correction Open Access

[Erratum] Identification of UBE2T as an independent prognostic biomarker for gallbladder cancer

Xuan Zhu, Tao Li, Xing Niu, Lijie Chen, Chunlin Ge
Article Number: 364
Published online on: 15 October 2020

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Article Open Access

Mechanism of intrinsic resistance of lung squamous cell carcinoma to epithelial growth factor receptor‑tyrosine kinase inhibitors revealed by high‑throughput RNA interference screening

Lixia Ju, Zhiyi Dong, Juan Yang, Minghua Li
Article Number: 363
Published online on: 15 October 2020

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Article Open Access

Bex1 significantly contributes to the proliferation and invasiveness of malignant tumor cells

Takefumi Doi, Hiroyuki Ogawa, Yugo Tanaka, Yoshitake Hayashi, Yoshimasa Maniwa
Article Number: 362
Published online on: 14 October 2020

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Article Open Access

RNA interference‑mediated downregulation of phospholipid scramblase 1 expression in primary liver cancer in vitro

Liang Gui, Ying-Wei Zhu, Qiang Xu, Ju-Ju Huang, Ping Hua, Gao-Jue Wu, Jian Lu, Jing-Bin Ni, Hong Tang, Li-Li Zhang
Article Number: 361
Published online on: 14 October 2020

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Article Open Access

Interaction between regulatory T cells and mast cells via IL‑9 and TGF‑β production

Yi-Bin Zhao, Shao-Hui Yang, Jie Shen, Ke Deng, Qi Li, Yu Wang, Wei Cui, Hua Ye
Article Number: 360
Published online on: 14 October 2020

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Article Open Access

MicroRNA‑454‑3p inhibits cell proliferation and invasion in esophageal cancer by targeting insulin‑like growth factor 2 mRNA‑binding protein 1

Aiting Yan, Cuizhu Wang, Liangfeng Zheng, Jiebo Zhou, Yan Zhang
Article Number: 359
Published online on: 14 October 2020

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Article Open Access

Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells

Chunyu Liu, Fei Wang, Bin Wang, Ting Wu, Yue Wang, Wenbo Huo, Shuxia Zhang, Ying Su, Jinming Liu, Yumeng Liu, Jinghua Yu
Article Number: 358
Published online on: 14 October 2020

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Article Open Access

Genome‑wide methylation profiles in monozygotic twins with discordance for ovarian carcinoma

Ozge Sukruoglu Erdogan, Seref Bugra Tuncer, Seda Kilic, Demet Akdeniz Odemis, Gozde Kuru Turkcan, Betul Celik, Mukaddes Avsar, Hulya Yazici
Article Number: 357
Published online on: 14 October 2020

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Article Open Access

Coiled‑coil domain‑containing 68 promotes non‑small cell lung cancer cell proliferation in vitro

Tao Hua, Jie Ding, Jialing Xu, Yu Fan, Zejie Liu, Juanwen Lian
Article Number: 356
Published online on: 14 October 2020

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Article Open Access

Long non‑coding RNA MIAT promotes gastric cancer proliferation and metastasis via modulating the miR‑331‑3p/RAB5B pathway

Xiao-Mei Li, Yan-Yan Jiao, Bao-Hong Luan, Hong-Xia Wu, Rong-Rong Wang, Jie Zhong
Article Number: 355
Published online on: 13 October 2020

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Article Open Access

Establishment of a type II insulin‑like growth factor receptor gene site‑integrated SKBR3 cell line using CRISPR/Cas9

Xinyu Ma, Ru Cao, Haiyan Xiao, Zhongwei Cao
Article Number: 354
Published online on: 11 October 2020

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Article Open Access

MicroRNA‑155‑5p inhibits the invasion and migration of prostate cancer cells by targeting SPOCK1

Lin-Ya Yao, Jun Ma, Xue-Ming Zeng, Jun Ou‑yang
Article Number: 353
Published online on: 11 October 2020

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Article Open Access

Macrophages in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis

Sayaka Kobayashi, Masanao Saio, Misa Fujimori, Junko Hirato, Tetsunari Oyama, Toshio Fukuda
Article Number: 352
Published online on: 11 October 2020

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Article Open Access

Novel canine isocitrate dehydrogenase 1 mutation Y208C attenuates dimerization ability

Shota Kawakami, Masaki Michishita, Motoharu Sakaue, Masami Morimatsu, Mitsuki Uemura, Nobuaki Kashiwagi, Marika Maeda, Yukino Machida, Daigo Azakami, Ai S. Egusa, Eri Onozawa, Katsumi Ishioka, Masami Watanabe, Yoshikazu Tanaka, Toshinori Omi, Kazuhiko Ochiai
Article Number: 351
Published online on: 11 October 2020

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Article Open Access

Usefulness of serum miR‑1246/miR‑106b ratio in patients with esophageal squamous cell carcinoma

Isamu Hoshino, Fumitaka Ishige, Yosuke Iwatate, Hisashi Gunji, Fumiaki Shiratori, Naoki Kuwayama, Yoshihiro Nabeya, Nobuyoshi Takeshita, Hisahiro Matsubara
Article Number: 350
Published online on: 10 October 2020

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Article

Expression of the epigenetic H3K27me3 modifier genes KDM6A and EZH2 in patients with upper tract urothelial carcinoma

Yue Wang, Jin-Xia Zhang, Shu-Fang Wang, Yu Zhang, Hui-Ying He
Article Number: 349
Published online on: 10 October 2020

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Article Open Access

Kinesin family member 3A inhibits the carcinogenesis of non‑small cell lung cancer and prolongs survival

Yie Yang, Xiao Liu, Rui Li, Mengyu Zhang, Hong Wang, Yiqing Qu
Article Number: 348
Published online on: 10 October 2020

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Article Open Access

Low PTEN expression and overexpression of phosphorylated AktSer473 and AktThr308 are associated with poor overall survival in upper tract urothelial carcinoma

Wen-Hui Weng, Kai-Jie Yu, Liang-Chen Li, Yeu-Jye Pang, Ying-Tzu Chen, See-Tong Pang, Cheng-Keng Chuang
Article Number: 347
Published online on: 09 October 2020

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Article Open Access

Identification of AK4 as a novel therapeutic target for serous ovarian cancer

Minmin Huang, Xinlei Qin, Yuwei Wang, Furong Mao
Article Number: 346
Published online on: 08 October 2020

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Case Report Open Access

Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report

Xing Yu, Yong Wang, Qiuping Xie, Haichao Yan, Qunzi Zhao, Cheng Xiang, Maolin Zhang, Jin-Fan Li, Ping Wang
Article Number: 345
Published online on: 08 October 2020

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Article Open Access

Efficacy and safety of nanosomal docetaxel lipid suspension‑based chemotherapy in squamous cell carcinoma of the head and neck: A multicenter retrospective study

Saroj Kumar Das Majumdar, Sundaram Subramanian, Ghanashyam Biswas, Nisarg Joshi, Mujtaba A. Khan, Imran Ahmad
Article Number: 344
Published online on: 08 October 2020

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Case Report

Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review

Moonsik Kim, Jiyeon An, Sun Och Yoon, Seung Hyun Yong, Jin  Seok Kim, Woo Ick Yang, Ah Young Leem
Article Number: 343
Published online on: 08 October 2020

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Review Open Access

Association between the gut microbiota and patient responses to cancer immune checkpoint inhibitors (Review)

Jian Wang, Hong-Ru Yang, Dai-Jie Wang, Xing-Xia Wang
Article Number: 342
Published online on: 08 October 2020

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Article Open Access

Tumour stem cell markers CD133 and CD44 are useful prognostic factors after surgical resection of pancreatic neuroendocrine tumours

Zhonghai Sun, Dezhi Li, Hongmei Wu, Baohua Hou
Article Number: 341
Published online on: 08 October 2020

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Article Open Access

Effect of TTLL12 on tubulin tyrosine nitration as a novel target for screening anticancer drugs in vitro

Lingli Xue, Yan Zeng, Chuan Fang, Wei Cheng, Yadong Li
Article Number: 340
Published online on: 08 October 2020

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Article Open Access

miR‑451a suppression of IL‑6R can inhibit proliferation and increase apoptosis through the JAK2/STAT3 pathway in multiple myeloma

Ling Zhong, Zhuyu Xu, Xin Jin, Yuan He, Jianbo Zhang, Tao Jiang, Jiao Chen
Article Number: 339
Published online on: 08 October 2020

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Article Open Access

Genome‑wide analysis of microRNA to evaluate prognostic markers in isolated cancer glands and surrounding stroma in high‑grade serous ovarian carcinoma

Chie Sato, Mitsumasa Osakabe, Takayuki Nagasawa, Hiromu  Suzuki, Hiroaki Itamochi, Tsukasa Baba, Tamotsu Sugai
Article Number: 338
Published online on: 08 October 2020

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Case Report Open Access

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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