|
1
|
Kanthan R, Senger JL, Ahmed S and Kanthan
SC: Gallbladder cancer in the 21st century. J Oncol.
2015:9674722015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Are C, Ahmad H, Ravipati A, Croo D, Clarey
D, Smith L, Price RR, Butte JM, Gupta S, Chaturvedi A and Chowdhury
S: Global epidemiological trends and variations in the burden of
gallbladder cancer. J Surg Oncol. 115:580–590. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ma MZ, Li CX, Zhang Y, Weng MZ, Zhang MD,
Qin YY, Gong W and Quan ZW: Long non-coding RNA HOTAIR, a c-myc
activated driver of malignancy, negatively regulates miRNA-130a in
gallbladder cancer. Mol Cancer. 13:1562014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Weng M, Gong W, Ma M, Chu B, Qin Y, Zhang
M, Lun X, McFadden G, Forsyth P, Yang Y and Quan Z: Targeting
gallbladder cancer: Oncolytic virotherapy with myxoma virus is
enhanced by rapamycin in vitro and further improved by hyaluronan
in vivo. Mol Cancer. 13:822014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Millimouno FM, Dong J, Yang L, Li J and Li
X: Targeting apoptosis pathways in cancer and perspectives with
natural compounds from mother nature. Cancer Prev Res (Phila).
7:1081–1107. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Cragg GM and Newman DJ: Plants as a source
of anti-cancer agents. J Ethnopharmacol. 100:72–79. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Balunas MJ and Kinghorn AD: Drug discovery
from medicinal plants. Life Sci. 78:431–441. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Chin YW, Balunas MJ, Chai HB and Kinghorn
AD: Drug discovery from natural sources. AAPS J. 8:E239–E253. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Tada A, Kaneiwa Y, Shoji J and Shibata S:
Studies on the saponins of the root of platycodon grandiflorum A.
De candolle. I. Isolation and the structure of platycodin-D. Chem
Pharm Bulletin (Tokyo). 23:2965–2972. 1975. View Article : Google Scholar
|
|
10
|
Zhou R, Lu Z, Liu K, Guo J, Liu J, Zhou Y,
Yang J, Mi M and Xu H: Platycodin D induces tumor growth arrest by
activating FOXO3a expression in prostate cancer in vitro and in
vivo. Curr Cancer Drug Targets. 14:860–871. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Xu C, Sun G, Yuan G, Wang R and Sun X:
Effects of platycodin D on proliferation, apoptosis and PI3K/akt
signal pathway of human glioma U251 cells. Molecules.
19:21411–21423. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kim MO, Moon DO, Choi YH, Lee JD, Kim ND
and Kim GY: Platycodin D induces mitotic arrest in vitro, leading
to endoreduplication, inhibition of proliferation and apoptosis in
leukemia cells. Int J Cancer. 122:2674–2681. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Li T, Xu WS, Wu GS, Chen XP, Wang YT and
Lu JJ: Platycodin D induces apoptosis, and inhibits adhesion,
migration and invasion in hepG2 hepatocellular carcinoma cells.
Asian Pac J Cancer Prev. 15:1745–1749. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Yu JS and Kim AK: Platycodin D induces
apoptosis in MCF-7 human breast cancer cells. J Med Food.
13:298–305. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chun J, Joo EJ, Kang M and Kim YS:
Platycodin D induces anoikis and caspase-mediated apoptosis via p38
MAPK in AGS human gastric cancer cells. J Cell Biochem.
114:456–470. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Ahn KS, Noh EJ, Zhao HL, Jung SH, Kang SS
and Kim YS: Inhibition of inducible nitric oxide synthase and
cyclooxygenase II by platycodon grandiflorum saponins via
suppression of nuclear factor-kappaB activation in RAW 264.7 cells.
Life Sci. 76:2315–2328. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Chun J and Kim YS: Platycodin D inhibits
migration, invasion, and growth of MDA-MB-231 human breast cancer
cells via suppression of EGFR-mediated akt and MAPK pathways. Chem
Biol Interact. 205:212–221. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Li T, Tang ZH, Xu WS, Wu GS, Wang YF,
Chang LL, Zhu H, Chen XP, Wang YT, Chen Y and Lu JJ: Platycodin D
triggers autophagy through activation of extracellular
signal-regulated kinase in hepatocellular carcinoma HepG2 cells.
Eur J Pharmacol. 749:81–88. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Cosulich SC, Savory PJ and Clarke PR:
Bcl-2 regulates amplification of caspase activation by cytochrome
c. Curr Biol. 9:147–150. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Nuñez G and Clarke MF: The Bcl-2 family of
proteins: Regulators of cell death and survival. Trends Cell Biol.
4:399–403. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Li T, Chen X, Chen X, Ma DL, Leung CH and
Lu JJ: Platycodin D potentiates proliferation inhibition and
apoptosis induction upon AKT inhibition via feedback blockade in
non-small cell lung cancer cells. Sci Rep. 6:379972016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Li T, Xu XH, Tang ZH, Wang YF, Leung CH,
Ma DL, Chen XP, Wang YT, Chen Y and Lu JJ: Platycodin D induces
apoptosis and triggers ERK- and JNK-mediated autophagy in human
hepatocellular carcinoma BEL-7402 cells. Acta Pharmacol Sin.
36:1503–1513. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Bauvois B: New facets of matrix
metalloproteinases MMP-2 and MMP-9 as cell surface transducers:
Outside-in signaling and relationship to tumor progression. Biochim
Biophys Acta. 1825:29–36. 2012.PubMed/NCBI
|
|
24
|
Cory S and Adams JM: The Bcl2 family:
Regulators of the cellular life-or-death switch. Nat Rev Cancer.
2:647–656. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
25
|
Thornberry NA and Lazebnik Y: Caspases:
Enemies within. Science. 281:1312–1316. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Campbell KJ and Tait SW: Targeting BCL-2
regulated apoptosis in cancer. Open Biol. 8:1800022018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Wang W, Guo Q, You Q, Zhang K, Yang Y, Yu
J, Liu W, Zhao L, Gu H, Hu Y, et al: Involvement of bax/bcl-2 in
wogonin-induced apoptosis of human hepatoma cell line SMMC-7721.
Anticancer Drugs. 17:797–805. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Jin CY, Moon DO, Choi YH, Lee JD and Kim
GY: Bcl-2 and caspase-3 are major regulators in agaricus
blazei-induced human leukemic U937 cell apoptosis through
dephoshorylation of akt. Biol Pharm Bull. 30:1432–1437. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Vaux DL, Cory S and Adams JM: Bcl-2 gene
promotes haemopoietic cell survival and cooperates with c-myc to
immortalize pre-B cells. Nature. 335:440–442. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Cheng N, Janumyan YM, Didion L, Van
Hofwegen C, Yang E and Knudson CM: Bcl-2 inhibition of T-cell
proliferation is related to prolonged T-cell survival. Oncogene.
23:3770–3780. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Pistritto G, Trisciuoglio D, Ceci C,
Garufi A and D'Orazi G: Apoptosis as anticancer mechanism: Function
and dysfunction of its modulators and targeted therapeutic
strategies. Aging (Albany NY). 8:603–619. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Elmore S: Apoptosis: A review of
programmed cell death. Toxicol Pathol. 35:495–516. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zaman S, Wang R and Gandhi V: Targeting
the apoptosis pathway in hematologic malignancies. Leuk Lymphoma.
55:1980–1992. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Xia Z, Dickens M, Raingeaud J, Davis RJ
and Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases
on apoptosis. Science. 270:1326–1331. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Stark GR and Taylor WR: Control of the
G2/M transition. Mol Biotechnol. 32:227–248. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Malumbres M: Cyclin-dependent kinases.
Genome Biol. 15:1222014. View
Article : Google Scholar : PubMed/NCBI
|