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Case Report

Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review

  • Authors:
    • Moonsik Kim
    • Jiyeon An
    • Sun Och Yoon
    • Seung Hyun Yong
    • Jin  Seok Kim
    • Woo Ick Yang
    • Ah Young Leem
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea, Division of Pulmonology, Department of Internal Medicine, Institute of Chest Diseases, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea, Division of Hematology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
  • Article Number: 343
    |
    Published online on: October 8, 2020
       https://doi.org/10.3892/ol.2020.12206
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Abstract

Primary effusion lymphoma (PEL) is a B‑cell non‑Hodgkin's lymphoma that is usually characterized by lymphomatous effusions in the body cavity without any detectable tumor masses. According to the World Health Organization (WHO) schema for tumor classification, PEL is defined by the presence of human herpesvirus 8 (HHV8) in malignant lymphoid cells. However, a subset of effusion‑based B‑cell lymphoma is not HHV8‑positive and exhibits different clinicopathological characteristics. The 2017 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues does not list HHV8‑negative effusion‑based lymphoma, which remains an underappreciated B‑cell lymphoma, as an individual entity. The present study reports a case of this rare type of lymphoma with indolent clinical behavior in a 75‑year‑old male patient receiving only symptomatic treatment. Additionally, a review of similar cases reported in the English literature is presented.
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Copy and paste a formatted citation
Spandidos Publications style
Kim M, An J, Yoon SO, Yong SH, Kim JS, Yang WI and Leem AY: Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review. Oncol Lett 20: 343, 2020.
APA
Kim, M., An, J., Yoon, S.O., Yong, S.H., Kim, J.S., Yang, W.I., & Leem, A.Y. (2020). Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review. Oncology Letters, 20, 343. https://doi.org/10.3892/ol.2020.12206
MLA
Kim, M., An, J., Yoon, S. O., Yong, S. H., Kim, J. S., Yang, W. I., Leem, A. Y."Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review". Oncology Letters 20.6 (2020): 343.
Chicago
Kim, M., An, J., Yoon, S. O., Yong, S. H., Kim, J. S., Yang, W. I., Leem, A. Y."Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review". Oncology Letters 20, no. 6 (2020): 343. https://doi.org/10.3892/ol.2020.12206
Copy and paste a formatted citation
x
Spandidos Publications style
Kim M, An J, Yoon SO, Yong SH, Kim JS, Yang WI and Leem AY: Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review. Oncol Lett 20: 343, 2020.
APA
Kim, M., An, J., Yoon, S.O., Yong, S.H., Kim, J.S., Yang, W.I., & Leem, A.Y. (2020). Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review. Oncology Letters, 20, 343. https://doi.org/10.3892/ol.2020.12206
MLA
Kim, M., An, J., Yoon, S. O., Yong, S. H., Kim, J. S., Yang, W. I., Leem, A. Y."Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review". Oncology Letters 20.6 (2020): 343.
Chicago
Kim, M., An, J., Yoon, S. O., Yong, S. H., Kim, J. S., Yang, W. I., Leem, A. Y."Human herpesvirus 8‑negative effusion‑based lymphoma with indolent clinical behavior in an elderly patient: A case report and literature review". Oncology Letters 20, no. 6 (2020): 343. https://doi.org/10.3892/ol.2020.12206
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