Open Access

Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report

  • Authors:
    • Xing Yu
    • Yong Wang
    • Qiuping Xie
    • Haichao Yan
    • Qunzi Zhao
    • Cheng Xiang
    • Maolin Zhang
    • Jin-Fan Li
    • Ping Wang
  • View Affiliations

  • Published online on: October 8, 2020     https://doi.org/10.3892/ol.2020.12208
  • Article Number: 345
  • Copyright: © Yu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Thyroid paraganglioma (TP) is an uncommon neuroendocrine tumor with potential for misdiagnosis. Case 1 (male; 44 years old) presented with hoarseness for 3 months. A 2.5‑cm gray nodule in the left thyroid was diagnosed as TP by immunohistochemistry. Lymph node metastasis was confirmed by H&E staining and immunohistochemistry. The patient was followed‑up for 3 years without any signs of recurrence or metastasis. Case 2 (female; 39 years old) presented with an asymptomatic but rapidly growing thyroid nodule. The patient underwent thyroidectomy 8 years ago (2008) and was diagnosed with TP postoperatively. The patient was diagnosed with recurrence and exhibited trachea invasion. Thyroidectomy and partial trachea resection were performed. A literature review revealed that 62 other cases of TP have been reported, and most of them exhibited low malignant potential. However, the two cases presented in the current case report exhibited a high malignant potential, accompanied by lymph node metastasis or trachea invasion, and these features imply that the choice of treatment for patients should be based on their different degrees of malignancy.
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December-2020
Volume 20 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Yu X, Wang Y, Xie Q, Yan H, Zhao Q, Xiang C, Zhang M, Li J and Wang P: Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report. Oncol Lett 20: 345, 2020
APA
Yu, X., Wang, Y., Xie, Q., Yan, H., Zhao, Q., Xiang, C. ... Wang, P. (2020). Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report. Oncology Letters, 20, 345. https://doi.org/10.3892/ol.2020.12208
MLA
Yu, X., Wang, Y., Xie, Q., Yan, H., Zhao, Q., Xiang, C., Zhang, M., Li, J., Wang, P."Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report". Oncology Letters 20.6 (2020): 345.
Chicago
Yu, X., Wang, Y., Xie, Q., Yan, H., Zhao, Q., Xiang, C., Zhang, M., Li, J., Wang, P."Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: A case report". Oncology Letters 20, no. 6 (2020): 345. https://doi.org/10.3892/ol.2020.12208