Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
February-2021 Volume 21 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2021 Volume 21 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Article Open Access

Predictive value of baseline 18F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy

  • Authors:
    • Lili Zhu
    • Yankai Meng
    • Lili Guo
    • Hanqing Zhao
    • Yue Shi
    • Shaodong Li
    • Anming Wang
    • Xiaojun Zhang
    • Jing Shi
    • Jie Zhu
    • Kai Xu
  • View Affiliations / Copyright

    Affiliations: The First School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China, Department of Radiology, Huaihai Hospital Affiliated with Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China
    Copyright: © Zhu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 132
    |
    Published online on: December 18, 2020
       https://doi.org/10.3892/ol.2020.12393
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study aimed to investigate the prognostic value of baseline 18F‑FDG PET/CT quantitative parameters and interim treatment response, and to assess whether the combination of these could improve the predictive efficacy in patients with diffuse large B‑cell lymphoma (DLBCL) receiving R‑CHOP chemotherapy. PET/CT images and clinical data of 64 patients with DLBCL who had undergone 18F‑FDG PET/CT scan before and after 3 or 4 cycles of R‑CHOP chemotherapy were retrospectively reviewed. The quantitative parameters including standardized uptake value (SUV), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and maximum diameter of the maximum lesion (Dmax) were measured on baseline PET/CT images. Cox proportional hazards model was used to evaluate the influence of baseline PET/CT parameters, clinical indicators and interim treatment response on prognosis. Survival analysis was performed using Kaplan‑Meier method. Receiver operating characteristic (ROC) curve analysis was performed to estimate the predictive efficacy of the combination of baseline PET/CT parameters and interim treatment response. Ann Arbor stage, International Prognostic Index (IPI), lactate dehydrogenase (LDH), necrosis, MTVmax, TLGmax, Dmax and interim treatment response showed association with 2‑year progression‑free survival (PFS, P<0.05). LDH, necrosis, MTVmax, MTVsum, TLGmax, TLGsum, Dmax and interim treatment response showed association with 2‑year overall survival (OS, P<0.05). Ann Arbor stage, Dmax and interim treatment response were found to be independent predictors of 2‑year PFS (P<0.05), while Dmax and interim treatment response were found to be independent predictors of 2‑year OS (P<0.05). The PFS and OS curves of Dmax <5.7 cm group and Dmax ≥5.7 cm group, complete response (CR) group and non‑CR group were significantly different, respectively (P<0.05). The baseline 18F‑FDG PET/CT parameters and interim treatment response have important prognostic values in DLBCL patients who received R‑CHOP chemotherapy. Combined application of Dmax and interim treatment response improved the predictive efficacy of 2‑year PFS. It may be helpful to identify patients who are at high‑risk of relapse and to guide early clinical intervention of these patients.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Crombie JL and Armand P: Diffuse large B-cell lymphoma and high-grade B-cell lymphoma: Genetic classification and its implications for prognosis and treatment. Hematol Oncol Clin North Am. 33:575–585. 2019. View Article : Google Scholar

2 

International Non-Hodgkins Lymphoma Prognostic Factors Project: A predictive model for aggressive non-Hodgkins lymphoma. N Engl J Med. 329:987–994. 1993. View Article : Google Scholar

3 

Vaidya R and Witzig TE: Prognostic factors for diffuse large B-cell lymphoma in the R(X)CHOP era. Ann Oncol. 25:2124–2133. 2014. View Article : Google Scholar

4 

Sampedro F, Domenech A and Escalera S: Obtaining quantitative global tumoral state indicators based on whole-body PET/CT scans: A breast cancer case study. Nucl Med Commun. 35:362–371. 2014. View Article : Google Scholar

5 

Park S, Moon SH, Park LC, Hwang DW, Ji JH, Maeng CH, Cho SH, Ahn HK, Lee JY, Kim SJ, et al: The impact of baseline and interim PET/CT parameters on clinical outcome in patients with diffuse large B cell lymphoma. Am J Hematol. 87:937–940. 2012. View Article : Google Scholar

6 

Koff JL and Flowers CR: Prognostic modeling in diffuse large B-cell lymphoma in the era of immunochemotherapy: Where do we go from here? Cancer. 123:3222–3225. 2017. View Article : Google Scholar

7 

Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, et al: Genetic and functional drivers of diffuse large B cell lymphoma. Cell. 171:481–494.e15. 2017. View Article : Google Scholar

8 

Islam P, Goldstein J and Flowers CR: PET-derived tumor metrics predict DLBCL response and progression-free survival. Leuk Lymphoma. 60:1965–1971. 2019. View Article : Google Scholar

9 

Cottereau AS, Lanic H, Mareschal S, Meignan M, Vera P, Tilly H, Jardin F and Becker S: Molecular profile and FDG-PET/CT total metabolic tumor volume improve risk classification at diagnosis for patients with diffuse large B-cell lymphoma. Clin Cancer Res. 22:3801–3809. 2016. View Article : Google Scholar

10 

Barrington SF, Mikhaeel NG, Kostakoglu L, Meignan M, Hutchings M, Müeller SP, Schwartz LH, Zucca E, Fisher RI, Trotman J, et al: Role of imaging in the staging and response assessment of lymphoma: Consensus of the international conference on malignant lymphomas imaging working group. J Clin Oncol. 32:3048–3058. 2014. View Article : Google Scholar

11 

Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, Lister TA; Alliance, Australasian Leukaemia and Lymphoma Group and Eastern Cooperative Oncology Group; European Mantle Cell Lymphoma Consortium, ; et al: Recommendations for initial evaluation, staging, and response assessment Hodgkin and non-Hodgkin lymphoma: The Lugano classification. J Clin Oncol. 32:3059–3068. 2014. View Article : Google Scholar

12 

Mikhaeel NG, Smith D, Dunn JT, Phillips M, Møller H, Fields PA, Wrench D and Barrington SF: Combination of baseline metabolic tumour volume and early response on PET/CT improves progression-free survival prediction in DLBCL. Eur J Nucl Med Mol Imaging. 43:1209–1219. 2016. View Article : Google Scholar

13 

Zhang YY, Song L, Zhao MX and Hu K: A better prediction of progression-free survival in diffuse large B-cell lymphoma by a prognostic model consisting of baseline TLG and %ΔSUVmax. Cancer Med. 5:5137–5147. 2019. View Article : Google Scholar

14 

Sehn LH, Berry B, Chhanabhai M, Fitzgerald C, Gill K, Hoskins P, Klasa R, Savage KJ, Shenkier T, Sutherland J, et al: The revised international prognostic index (R-IPI) is a better predictor of outcome than the standard IPI for patients with diffuse large B-cell lymphoma treated with R-CHOP. Blood. 109:1857–1861. 2007. View Article : Google Scholar

15 

Zhou Z, Sehn LH, Rademaker AW, Gordon LI, Lacasce AS, Crosby-Thompson A, Vanderplas A, Zelenetz AD, Abel GA, Rodriguez MA, et al: An enhanced international prognostic index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era. Blood. 123:837–842. 2014. View Article : Google Scholar

16 

Kwon SH, Kang DR, Kim J, Yoon JK, Lee SJ, Jeong SH, Lee HW and An YS: Prognostic value of negative interim 2-[18F]-fluoro-2-deoxy-d-glucose PET/CT in diffuse large B-cell lymphoma. Clin Radiol. 71:280–286. 2016. View Article : Google Scholar

17 

Parvez A, Tau N, Hussey D, Maganti M and Metser U: 18F-FDG PET/CT metabolic tumor parameters and radiomics features in aggressive non-Hodgkins lymphoma as predictors of treatment outcome and survival. Ann Nucl Med. 32:410–416. 2018. View Article : Google Scholar

18 

Kim TM, Paeng JC, Chun IK, Keam B, Jeon YK, Lee SH, Kim DW, Lee DS, Kim CW, Chung JK, et al: Total lesion glycolysis in positron emission tomography is a better predictor of outcome than the international prognostic index for patients with diffuse large B cell lymphoma. Cancer. 119:1195–1202. 2013. View Article : Google Scholar

19 

Esfahani SA, Heidari P, Halpern EF, Hochberg EP, Palmer EL and Mahmood U: Baseline total lesion glycolysis measured with 18F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: A pilot study. Am J Nucl Med Mol Imaging. 3:272–281. 2013.

20 

Song MK, Chung JS, Shin HJ, Lee SM, Lee SE, Lee HS, Lee GW, Kim SJ, Lee SM and Chung DS: Clinical significance of metabolic tumor volume by PET/CT in stages II and III of diffuse large B cell lymphoma without extranodal site involvement. Ann Hematol. 91:697–703. 2012. View Article : Google Scholar

21 

Tatsumi M, Isohashi K, Matsunaga K, Watabe T, Kato H, Kanakura Y and Hatazawa J: Volumetric and texture analysis on FDG PET in evaluating and predicting treatment response and recurrence after chemotherapy in follicular lymphoma. Int J Clin Oncol. 24:1292–1300. 2019. View Article : Google Scholar

22 

Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P and Storto G: F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma. Eur J Haematol. 92:382–389. 2014. View Article : Google Scholar

23 

Adams HJ, de Klerk JM, Fijnheer R, Heggelman BG, Dubois SV, Nievelstein RA and Kwee TC: Prognostic superiority of the national comprehensive cancer network international prognostic index over pretreatment whole-body volumetric-metabolic FDG PET/CT metrics in diffuse large B-cell lymphoma. Eur J Haematol. 94:532–539. 2015. View Article : Google Scholar

24 

Xie M, Zhai W, Cheng S, Zhang H, Xie Y and He W: Predictive value of F-18 FDG PET/CT quantization parameters for progression-free survival in patients with diffuse large B-cell lymphoma. Hematology. 21:99–105. 2016. View Article : Google Scholar

25 

Manohar K, Mittal BR, Bhattacharya A, Malhotra P and Varma S: Prognostic value of quantitative parameters derived on initial staging 18F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with high-grade non-Hodgkins lymphoma. Nucl Med Commun. 33:974–981. 2012. View Article : Google Scholar

26 

Fuertes S, Setoain X, Lopez-Guillermo A, Carrasco JL, Rodríguez S, Rovira J and Pons F: Interim FDG PET/CT as a prognostic factor in diffuse large B-cell lymphoma. Eur J Nucl Med Mol Imaging. 40:496–504. 2013. View Article : Google Scholar

27 

Wu X, Pertovaara H, Korkola P, Vornanen M, Järvenpää R, Dastidar P, Eskola H and Kellokumpu-Lehtinen PL: Early interim PET/CT predicts post-treatment response in diffuse large B-cell lymphoma. Acta Oncol. 53:1093–1099. 2014. View Article : Google Scholar

28 

Oñate-Ocaña LF, Cortés V, Castillo-Llanos R, Terrazas A, Garcia-Perez O, Pitalúa-Cortes Q, Ponce M, Dueñas-Gonzalez A and Candelaria M: Metabolic tumor volume changes assessed by interval 18fluorodeoxyglucose positron emission tomography-computed tomography for the prediction of complete response and survival in patients with diffuse large B-cell lymphoma. Oncol Lett. 16:1411–1418. 2018.

29 

Tateishi U, Tatsumi M, Terauchi T, Ando K, Niitsu N, Kim WS, Suh C, Ogura M and Tobinai K: Prognostic significance of metabolic tumor burden by positron emission tomography/computed tomography in patients with relapsed/refractory diffuse large B-cell lymphoma. Cancer Sci. 106:186–193. 2015. View Article : Google Scholar

30 

Petrich AM, Gandhi M, Jovanovic B, Castillo JJ, Rajguru S, Yang DT, Shah KA, Whyman JD, Lansigan F, Hernandez-Ilizaliturri FJ, et al: Impact of induction regimen and stem cell transplantation on outcomes in double-hit lymphoma: A multicenter retrospective analysis. Blood. 124:2354–2361. 2014. View Article : Google Scholar

31 

Huntington SF, Nasta SD, Schuster SJ, Doshi JA and Svoboda J: Utility of interim and end-of-treatment [18F]-fluorodeoxyglucose positron emission tomography-computed tomography in front line therapy of patients with diffuse large B-cell lymphoma. Leuk Lymphoma. 56:2579–2584. 2015. View Article : Google Scholar

32 

Pregno P, Chiappela A, Bellò M, Botto B, Ferrero S, Franceschetti S, Giunta F, Ladetto M, Limerutti G, Menga M, et al: Interim 18-FDG-PET/CT failed to predict the outcome in diffuse large B-cell lymphoma patients treated at the diagnosis with rituximab-CHOP. Blood. 119:2066–2073. 2012. View Article : Google Scholar

33 

Adams HJ and Kwee TC: Prognostic value of interim FDG-PET in R-CHOP-treated diffuse large B-cell lymphoma: Systematic review and meta-analysis. Crit Rev Oncol Hematol. 106:55–63. 2016. View Article : Google Scholar

34 

Jiang SY, Qin Y, Liu P, Yang J, Yang S, He X, Zhou S, Gui L, Zhang C, Zhou L, et al: A prognostic nomogram constructed for relapsed or refractory diffuse large B-cell lymphoma patients. Asia Pac J Clin Oncol. July 1–2019.(Online ahead of print). simplehttps://doi.org/10.1111/ajco.13222 View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhu L, Meng Y, Guo L, Zhao H, Shi Y, Li S, Wang A, Zhang X, Shi J, Zhu J, Zhu J, et al: Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy. Oncol Lett 21: 132, 2021.
APA
Zhu, L., Meng, Y., Guo, L., Zhao, H., Shi, Y., Li, S. ... Xu, K. (2021). Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy. Oncology Letters, 21, 132. https://doi.org/10.3892/ol.2020.12393
MLA
Zhu, L., Meng, Y., Guo, L., Zhao, H., Shi, Y., Li, S., Wang, A., Zhang, X., Shi, J., Zhu, J., Xu, K."Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy". Oncology Letters 21.2 (2021): 132.
Chicago
Zhu, L., Meng, Y., Guo, L., Zhao, H., Shi, Y., Li, S., Wang, A., Zhang, X., Shi, J., Zhu, J., Xu, K."Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy". Oncology Letters 21, no. 2 (2021): 132. https://doi.org/10.3892/ol.2020.12393
Copy and paste a formatted citation
x
Spandidos Publications style
Zhu L, Meng Y, Guo L, Zhao H, Shi Y, Li S, Wang A, Zhang X, Shi J, Zhu J, Zhu J, et al: Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy. Oncol Lett 21: 132, 2021.
APA
Zhu, L., Meng, Y., Guo, L., Zhao, H., Shi, Y., Li, S. ... Xu, K. (2021). Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy. Oncology Letters, 21, 132. https://doi.org/10.3892/ol.2020.12393
MLA
Zhu, L., Meng, Y., Guo, L., Zhao, H., Shi, Y., Li, S., Wang, A., Zhang, X., Shi, J., Zhu, J., Xu, K."Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy". Oncology Letters 21.2 (2021): 132.
Chicago
Zhu, L., Meng, Y., Guo, L., Zhao, H., Shi, Y., Li, S., Wang, A., Zhang, X., Shi, J., Zhu, J., Xu, K."Predictive value of baseline <sup>18</sup>F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy". Oncology Letters 21, no. 2 (2021): 132. https://doi.org/10.3892/ol.2020.12393
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team