|
1
|
Dekker E, Tanis PJ, Vleugels JLA, Kasi PM
and Wallace MB: Colorectal cancer. Lancet. 394:1467–1480. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
World Health Organization (WHO), . Cancer
fact sheets. WHO; Geneva: 2021, https://gco.iarc.fr/today/fact-sheets-cancersApril
12–2021
|
|
3
|
National Cancer Institute (NCI), . Cancer
Stat Facts: Colorectal Cancer. NCI; Bethesda, MD: 2021, https://seer.cancer.gov/statfacts/html/colorect.htmlOctober
10–2020
|
|
4
|
Rahib L, Smith BD, Aizenberg R, Rosenzweig
AB, Fleshman JM and Matrisian LM: Projecting cancer incidence and
deaths to 2030: The unexpected burden of thyroid, liver, and
pancreas cancers in the United States. Cancer Res. 74:2913–2921.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Conroy T, Hammel P, Hebbar M, Ben
Abdelghani M, Wei AC, Raoul JL, Choné L, Francois E, Artru P, Biagi
JJ, et al: FOLFIRINOX or gemcitabine as adjuvant therapy for
pancreatic cancer. N Engl J Med. 379:2395–2406. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
De Dosso S, Siebenhüner AR, Winder T,
Meisel A, Fritsch R, Astaras C, Szturz P and Borner M: Treatment
landscape of metastatic pancreatic cancer. Cancer Treat Rev.
96:1021802021. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Fededa JP and Gerlich DW: Molecular
control of animal cell cytokinesis. Nat Cell Biol. 14:440–447.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Gruneberg U, Neef R, Li X, Chan EH,
Chalamalasetty RB, Nigg EA and Barr FA: KIF14 and citron kinase act
together to promote efficient cytokinesis. J Cell Biol.
172:363–372. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lens SMA and Medema RH: Cytokinesis
defects and cancer. Nat Rev Cancer. 19:32–45. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Jiang W, Jimenez G, Wells NJ, Hope TJ,
Wahl GM, Hunter T and Fukunaga R: PRC1: A human mitotic
spindle-associated CDK substrate protein required for cytokinesis.
Mol Cell. 2:877–885. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Mollinari C, Kleman JP, Jiang W, Schoehn
G, Hunter T and Margolis RL: PRC1 is a microtubule binding and
bundling protein essential to maintain the mitotic spindle midzone.
J Cell Biol. 1570:1175–1186. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Miki H, Okada Y and Hirokawa N: Analysis
of the kinesin superfamily: Insights into structure and function.
Trends Cell Biol. 15:467–476. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kurasawa Y, Earnshaw WC, Mochizuki Y,
Dohmae N and Todokoro K: Essential roles of KIF4 and its binding
partner PRC1 in organized central spindle midzone formation. EMBO
J. 23:3237–3248. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wordeman L: How kinesin motor proteins
drive mitotic spindle function: Lessons from molecular assays.
Semin Cell Dev Biol. 21:260–268. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hammond JW, Cai D, Blasius TL, Li Z, Jiang
Y, Jih GT, Meyhofer E and Verhey KJ: Mammalian Kinesin-3 motors are
dimeric in vivo and move by processive motility upon release of
autoinhibition. PLoS Biol. 7:e722009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Singel SM, Cornelius C, Zaganjor E, Batten
K, Sarode VR, Buckley DL, Peng Y, John GB, Li HC, Sadeghi N, et al:
KIF14 promotes AKT phosphorylation and contributes to
chemoresistance in triple-negative breast cancer. Neoplasia.
16:247–256. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Carleton M, Mao M, Biery M, Warrener P,
Kim S, Buser C, Marshall CG, Fernandes C, Annis J and Linsley PS:
RNA interference-mediated silencing of mitotic kinesin KIF14
disrupts cell cycle progression and induces cytokinesis failure.
Mol Cell Biol. 26:3853–3863. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Gai M, Camera P, Dema A, Bianchi F, Berto
G, Scarpa E, Germena G and Di Cunto F: Citron kinase controls
abscission through RhoA and anillin. Mol Biol Cell. 22:3768–3778.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Bassi ZI, Audusseau M, Riparbelli MG,
Callaini G and D'Avino PP: Citron kinase controls a molecular
network required for midbody formation in cytokinesis. Proc Natl
Acad Sci USA. 110:9782–9787. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Gai M, Bianchi FT, Vagnoni C, Vernì F,
Bonaccorsi S, Pasquero S, Berto GE, Sgrò F, Chiotto AA, Annaratone
L, et al: ASPM and CITK regulate spindle orientation by affecting
the dynamics of astral microtubules. EMBO Rep. 18:18702017.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Brynychova V, Ehrlichova M, Hlavac V,
Nemcova-Furstova V, Pecha V, Leva J, Trnkova M, Mrhalova M, Kodet
R, Vrana D, et al: Genetic and functional analyses do not explain
the association of high PRC1 expression with poor survival of
breast carcinoma patients. Biomed Pharmacother. 83:857–864. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Ehrlichova M, Mohelnikova-Duchonova B,
Hrdy J, Brynychova V, Mrhalova M, Kodet R, Rob L, Pluta M, Gut I,
Soucek P and Vaclavikova R: The association of taxane resistance
genes with the clinical course of ovarian carcinoma. Genomics.
102:96–101. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Li X, Huang W, Huang W, Wei T, Zhu W, Chen
G and Zhang J: Kinesin family members KIF2C/4A/10/11/14/18B/20A/23
predict poor prognosis and promote cell proliferation in
hepatocellular carcinoma. Am J Transl Res. 12:1614–1639.
2020.PubMed/NCBI
|
|
24
|
Shou J, Yu C, Zhang D and Zhang Q:
Overexpression of citron rho-interacting serine/threonine kinase
associated with poor outcome in bladder cancer. J Cancer.
11:4173–4180. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Liu J, Dou J, Wang W, Liu H, Qin Y, Yang
Q, Jiang W, Liang Y, Liu Y, He J, et al: High expression of citron
kinase predicts poor prognosis of prostate cancer. Oncol Lett.
19:1815–1823. 2020.PubMed/NCBI
|
|
26
|
Hlavata I, Mohelnikova-Duchonova B,
Vaclavikova R, Liska V, Pitule P, Novak P, Bruha J, Vycital O,
Holubec L, Treska V, et al: The role of ABC transporters in
progression and clinical outcome of colorectal cancer. Mutagenesis.
27:187–196. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Sobin LH and Wittekind C: TNM
Classification of Malignant Tumors. 6th edition. Wiley-Liss; New
York, NY: 2002
|
|
28
|
Therasse P, Eisenhauer EA and Verweij J:
RECIST revisited: A review of validation studies on tumour
assessment. Eur J Cancer. 42:1031–1039. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mohelnikova-Duchonova B, Kocik M,
Duchonova B, Brynychova V, Oliverius M, Hlavsa J, Honsova E,
Mazanec J, Kala Z, Ojima I, et al: Hedgehog pathway overexpression
in pancreatic cancer is abrogated by new-generation taxoid
SB-T-1216. Pharmacogenomics J. 17:452–460. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mohelnikova-Duchonova B, Oliverius M,
Honsova E and Soucek P: Evaluation of reference genes and
normalization strategy for quantitative real-time PCR in human
pancreatic carcinoma. Dis Markers. 32:203–210. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Soucek P, Anzenbacher P, Skoumalová I and
Dvorák M: Expression of cytochrome P450 genes in CD34+
hematopoietic stem and progenitor cells. Stem Cells. 23:1417–1422.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Bustin SA, Benes V, Garson JA, Hellemans
J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL,
et al: The MIQE guidelines: minimum information for publication of
quantitative real-time PCR experiments. Clin Chem. 55:611–622.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Fekete J and Gyorffy B: ROCplot.org:
Validating predictive biomarkers of chemotherapy/hormonal
therapy/anti-HER2 therapy using transcriptomic data of 3,104 breast
cancer patients. Int J Cancer. 145:3140–3151. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Benjamini Y and Hochberg Y: Controlling
the false discovery rate: A practical and powerful approach to
multiple testing. J R Stat Soc Series B Stat Methodol. 57:289–300.
1995.
|
|
36
|
Li J, Dallmayer M, Kirchner T, Musa J and
Grünewald TGP: PRC1: Linking cytokinesis, chromosomal instability,
and cancer evolution. Trends Cancer. 2018:59–73. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
D'Avino PP: Citron kinase-renaissance of a
neglected mitotic kinase. J Cell Sci. 130:1701–1708. 2017.
|
|
38
|
Bianchi FT, Tocco C, Pallavicini G, Liu Y,
Vernì F, Merigliano C, Bonaccorsi S, El-Assawy N, Priano L, Gai M,
et al: Citron kinase deficiency leads to chromosomal instability
and TP53-sensitive microcephaly. Cell Rep. 18:1674–1686. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Corson TW, Zhu CQ, Lau SK, Shepherd FA,
Tsao MS and Gallie BL: KIF14 messenger RNA expression is
independently prognostic for outcome in lung cancer. Clin Cancer
Res. 13:3229–3234. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Thériault BL, Pajovic S, Bernardini MQ,
Shaw PA and Gallie BL: Kinesin family member 14: An independent
prognostic marker and potential therapeutic target for ovarian
cancer. Int J Cancer. 130:1844–1854. 2012. View Article : Google Scholar
|
|
41
|
Wang W, Shi Y, Li J, Cui W and Yang B:
Up-regulation of KIF14 is a predictor of poor survival and a novel
prognostic biomarker of chemoresistance to paclitaxel treatment in
cervical cancer. Biosci Rep. 36:e003152016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Yang Z, Li C, Yan C, Li J, Yan M, Liu B,
Zhu Z, Wu Y and Gu Q: KIF14 promotes tumor progression and
metastasis and is an independent predictor of poor prognosis in
human gastric cancer. Biochim Biophys Acta Mol Basis Dis.
1865:181–192. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chen J, Rajasekaran M, Xia H, Zhang X,
Kong SN, Sekar K, Seshachalam VP, Deivasigamani A, Goh BK, Ooi LL,
et al: The microtubule-associated protein PRC1 promotes early
recurrence of hepatocellular carcinoma in association with the
Wnt/β-catenin signalling pathway. Gut. 65:1522–1534. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Wang Y, Shi F, Xing GH, Xie P, Zhao N, Yin
YF, Sun SY, He J, Wang Y and Xuan SY: Protein regulator of
cytokinesis PRC1 confers chemoresistance and predicts an
unfavorable postoperative survival of hepatocellular carcinoma
patients. J Cancer. 8:801–808. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Bu H, Li Y, Jin C, Yu H, Wang X, Chen J,
Wang Y, Ma Y, Zhang Y and Kong B: Overexpression of PRC1 indicates
a poor prognosis in ovarian cancer. Int J Oncol. 56:685–696.
2020.PubMed/NCBI
|
|
46
|
Wang ZZ, Yang J, Jiang BH, Di JB, Gao P,
Peng L and Su XQ: KIF14 promotes cell proliferation via activation
of Akt and is directly targeted by miR-200c in colorectal cancer.
Int J Oncol. 53:1939–1952. 2018.PubMed/NCBI
|
|
47
|
Wu Z, Zhu X, Xu W, Zhang Y, Chen L, Qiu F,
Zhang B, Wu L, Peng Z and Tang H: Up-regulation of CIT promotes the
growth of colon cancer cells. Oncotarget. 8:71954–71964. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Birkbak NJ, Eklund AC, Li Q, McClelland
SE, Endesfelder D, Tan P, Tan IB, Richardson AL, Szallasi Z and
Swanton C: Paradoxical relationship between chromosomal instability
and survival outcome in cancer. Cancer Res. 71:3447–3452. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Bakhoum SF and Cantley LC: The
multifaceted role of chromosomal instability in cancer and its
microenvironment. Cell. 174:1347–1360. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Zhou Z, Cheng Y, Jiang Y, Liu S, Zhang M,
Liu J and Zhao Q: Ten hub genes associated with progression and
prognosis of pancreatic carcinoma identified by co-expression
analysis. Int J Biol Sci. 14:124–136. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Wu M, Li X, Liu R, Yuan H, Liu W and Liu
Z: Development and validation of a metastasis-related gene
signature for predicting the overall survival in patients with
pancreatic ductal adenocarcinoma. J Cancer. 11:6299–6318. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Jin D, Jiao Y, Ji J, Jiang W, Ni W, Wu Y,
Ni R, Lu C, Qu L, Ni H, et al: Identification of prognostic risk
factors for pancreatic cancer using bioinformatics analysis. PeerJ.
8:e93012020. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Cong L, Bai Z, Du Y and Cheng Y: Citron
rho-interacting serine/threonine kinase promotes HIF1a-CypA
signaling and growth of human pancreatic adenocarcinoma. Biomed Res
Int. 2020:92108912020. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Nicolle R, Raffenne J, Paradis V,
Couvelard A, de Reynies A, Blum Y and Cros J: Prognostic biomarkers
in pancreatic cancer: Avoiding errata when using the TCGA dataset.
Cancers (Basel). 11:1262019. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Wittel UA, Lubgan D, Ghadimi M, Belyaev O,
Uhl W, Bechstein WO, Grützmann R, Hohenberger WM, Schmid A,
Jacobasch L, et al: Consensus in determining the resectability of
locally progressed pancreatic ductal adenocarcinoma-results of the
Conko-007 multicenter trial. BMC Cancer. 19:9792019. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Rush A, Spring K and Byrne JA: A critical
analysis of cancer biobank practices in relation to biospecimen
quality. Biophys Rev. 7:369–378. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Wittel UA, Lubgan D, Ghadimi M, Belyaev O,
Uhl W, Bechstein WO, Grützmann R, Hohenberger WM, Schmid A,
Jacobasch L, et al: Consensus in determining the resectability of
locally progressed pancreatic ductal adenocarcinoma-results of the
Conko-007 multicenter trial. BMC Cancer. 19:9792019. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
O'Hurley G, Sjöstedt E, Rahman A, Li B,
Kampf C, Pontén F, Gallagher WM and Lindskog C: Garbage in, garbage
out: A critical evaluation of strategies used for validation of
immunohistochemical biomarkers. Mol Oncol. 8:783–798. 2014.
View Article : Google Scholar
|
|
59
|
Maier T, Guell M and Serrano L:
Correlation of mRNA and protein in complex biological samples. FEBS
Lett. 583:3966–3973. 2009. View Article : Google Scholar : PubMed/NCBI
|
