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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2021 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Targeting FHL2‑E‑cadherin axis by miR‑340‑5p attenuates colon cancer cell migration and invasion

Anwar Algaber, Raed Madhi, Avin Hawez, Carl-Fredrik Rönnow, Milladur Rahman
Article Number: 637
Published online on: 03 July 2021

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Review Open Access

Management of patients with chronic lymphocytic leukemia during the SARS‑CoV‑2 pandemic (Review)

Romeo Gabriel Mihaila
Article Number: 636
Published online on: 03 July 2021

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Article Open Access

Dose distribution effects of spot‑scanning proton beam therapy equipped with a multi‑leaf collimator for pediatric brain tumors

Nobuyoshi Fukumitsu, Tomohiro Yamashita, Masayuki Mima, Yusuke Demizu, Takeshi Suzuki, Toshinori Soejima
Article Number: 635
Published online on: 01 July 2021

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Article Open Access

Calponin 3 suppresses proliferation, migration and invasion of non‑small cell lung cancer cells

Chenglin Yang, Shiping Zhu, Weifeng Feng, Xuexin Chen
Article Number: 634
Published online on: 01 July 2021

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Article Open Access

Efficient pre‑treatment for pancreatic cancer using chloroquine‑loaded nanoparticles targeting pancreatic stellate cells

Sokichi Matsumoto, Kohei Nakata, Akiko Sagara, Weiyu Guan, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 633
Published online on: 01 July 2021

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Review

Advances in the role of autophagy in the development of retinoblastoma (Review)

Teng Wan, Mingyuan Fu, Zhuan Wu, Xue Gao, Shouhong Zhou
Article Number: 632
Published online on: 01 July 2021

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Article Open Access

Rosmanol induces breast cancer cells apoptosis by regulating PI3K/AKT and STAT3/JAK2 signaling pathways

Dongjun Jiang, Jiaqi Xu, Sitong Liu, Moussa Ide Nasser, Wei Wei, Tianjiao Mao, Xintong Liu, Xiaopan Zou, Jiang Li, Xiaomeng Li
Article Number: 631
Published online on: 01 July 2021

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Article Open Access

HSP60‑knockdown suppresses proliferation in colorectal cancer cells via activating the adenine/AMPK/mTOR signaling pathway

Jianying Guo, Songbiao Zhu, Haiteng Deng, Renhua Xu
Article Number: 630
Published online on: 01 July 2021

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Article

Pigment epithelium‑derived factor inhibits advanced glycation end product‑induced proliferation, VEGF and MMP‑9 expression in breast cancer cells via interaction with laminin receptor

Shiori Tsuruhisa, Takanori Matsui, Yoshinori Koga, Ami Sotokawauchi, Minoru Yagi, Sho-Ichi Yamagishi
Article Number: 629
Published online on: 30 June 2021

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Article Open Access

Aqueous extracts of Sanghuangporus vaninii induce S‑phase arrest and apoptosis in human melanoma A375 cells

Taihen Yu, Shi Zhong, Yuqing Sun, Haiyan Sun, Weiguo Chen, Yougui Li, Jianxun Zhu, Longxi Lu, Jinxi Huo
Article Number: 628
Published online on: 30 June 2021

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Article Open Access

Suppression of miR‑106a‑5p expression inhibits tumorigenesis via increasing CELF‑2 expression in spinal cord glioma

Hao Xu, Fei Wang, Lin Wang
Article Number: 627
Published online on: 30 June 2021

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Article Open Access

MicroRNA‑203‑3p inhibits the proliferation, invasion and migration of pancreatic cancer cells by downregulating fibroblast growth factor 2

Xi-Feng Fu, Hai-Chao Zhao, Chuan-Li Yang, Chang-Zhou Chen, Kang Wang, Fei Gao, Yang-Zhang Tian, Hao-Liang Zhao
Article Number: 626
Published online on: 30 June 2021

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Article Open Access

Association between cellular immune response and spleen weight in mice with hepatocellular carcinoma

Wei Jiang, Yu Li, Shuqun Zhang, Guangyao Kong, Zongfang Li
Article Number: 625
Published online on: 30 June 2021

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Article Open Access

lncRNA LOXL1‑AS1 promotes liver cancer cell proliferation and migration by regulating the miR‑377‑3p/NFIB axis

Wei Yu, Yong Dai
Article Number: 624
Published online on: 29 June 2021

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Article Open Access

Comprehensive serum and tissue microRNA profiling in dedifferentiated liposarcoma

Isaku Kohama, Naofumi Asano, Juntaro Matsuzaki, Yusuke Yamamoto, Tomofumi Yamamoto, Ryou-U Takahashi, Eisuke Kobayashi, Satoko Takizawa, Hiromi Sakamoto, Ken Kato, Hiroyuki Fujimoto, Hirotaka Chikuda, Akira Kawai, Takahiro Ochiya
Article Number: 623
Published online on: 29 June 2021

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Article Open Access

In vitro assessment of the efficiency of the PIM‑1 kinase pharmacological inhibitor as a potential treatment for Burkitt's lymphoma

Mona Alsubaie, Sabine Matou‑Nasri, Abdullah Aljedai, Ahmed  Alaskar, Hamad Al‑Eidi, Sarah A. Albabtain, Khawlah E. Aldilaijan, Manal Alsayegh, Ibrahim B. Alabdulkareem
Article Number: 622
Published online on: 29 June 2021

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Article Open Access

Effects of lncRNA ANRIL‑knockdown on the proliferation, apoptosis and cell cycle of gastric cancer cells

Xueqian Hu, Ting Lou, Chunying Yuan, Yongsheng Wang, Xiaolong Tu, Yi Wang, Tingsu Zhang
Article Number: 621
Published online on: 28 June 2021

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Article

Mammospheres of letrozole-resistant breast cancer cells enhance breast cancer aggressiveness

Jankiben R. Patel, Karen M. Gallegos, Rashidra R. Walker, A. Michael Davidson, Ian Davenport, Syreeta L. Tilghman
Article Number: 620
Published online on: 28 June 2021

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Article Open Access

hsa_circ_0060975 is highly expressed and predicts a poor prognosis in gastric cancer

Peng Xu, Xiaolan Xu, Lixiang Zhang, Zhengnan Li, Jianjun Qiang, Jie Yao, Aman Xu
Article Number: 619
Published online on: 24 June 2021

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Article Open Access

Diversity and shared T‑cell receptor repertoire analysis in esophageal squamous cell carcinoma

Tomoya Sudo, Akihiko Kawahara, Kazuo Ishi, Atsushi Mizoguchi, Sachiko Nagasu, Masashi Nakagawa, Masahiro Fujisaki, Haruhiro Hino, Kouhei Saisho, Hideaki Kaku, Satoru Matono, Naoki Mori, Jun Akiba, Akira Yamada, Yoshito Akagi
Article Number: 618
Published online on: 24 June 2021

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Article

MicroRNA‑148a‑3p inhibits the proliferation of cervical cancer cells by regulating the expression levels of DNMT1 and UTF1

Qing Chen, Yidong Wang, Huimin Dang, Xiaoling Wu
Article Number: 617
Published online on: 24 June 2021

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Article Open Access

Pseudogene legumain promotes thyroid carcinoma progression via the microRNA‑495/autophagy pathway

Jie Sun, Yicheng Peng, Jianxia Liu, Hao Zhou, Liang Sun, Qin He, Enqiao Yu
Article Number: 616
Published online on: 24 June 2021

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Article Open Access

Metformin suppresses breast cancer growth via inhibition of cyclooxygenase‑2

Bin Shi, Xinyu Hu, Huimin He, Wenzheng Fang
Article Number: 615
Published online on: 23 June 2021

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Article Open Access

Diagnostic potential of extracellular vesicle‑associated microRNA‑10b and tumor markers for lung adenocarcinoma

Guangda Yuan, Hongya Xie, Tengteng Wei, Donglin Zhu, Chuanyu Zhang, Yong Yang
Article Number: 614
Published online on: 23 June 2021

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Article Open Access

PD‑1 blockade enhances cytokine‑induced killer cell‑mediated cytotoxicity in B‑cell non‑Hodgkin lymphoma cell lines

Yutao Li, Amit Sharma, Maurits W.J.R. Bloemendal, Roland Schmidt‑Wolf, Miroslaw Kornek, Ingo G.H. Schmidt‑Wolf
Article Number: 613
Published online on: 23 June 2021

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Retraction Open Access

[Retracted] miR‑154 inhibits migration and invasion of human non‑small cell lung cancer by targeting ZEB2

Xingyu Lin, Zhiguang Yang, Peng Zhang, Yunpeng Liu, Guoguang Shao
Article Number: 612
Published online on: 18 June 2021

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Correction Open Access

[Corrigendum] Circulating extracellular vesicle‑encapsulated microRNA as screening biomarkers for intraductal papillary mucinous neoplasm

Yuki Sato, Rei Suzuki, Tadayuki Takagi, Mitsuru Sugimoto, Hiromasa Ohira
Article Number: 611
Published online on: 17 June 2021

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Article Open Access

Targeting glioma cells by antineoplastic activity of reversine

Camila Hirakata, Keli Lima, Bruna Oliveira De Almeida, Lívia Bassani Lins De Miranda, Katharine Gurgel Dias Florêncio, Luciana Costa Furtado, Leticia Veras Costa-Lotufo, João Agostinho Machado-Neto
Article Number: 610
Published online on: 15 June 2021

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Article Open Access

Melatonin inhibits gallbladder cancer cell migration and invasion via ERK‑mediated induction of epithelial‑to‑mesenchymal transition

Hongwei Tang, Xiaoyi Shi, Pengfei Zhu, Wenzhi Guo, Jie Li, Bing Yan, Shuijun Zhang
Article Number: 609
Published online on: 15 June 2021

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Article Open Access

MicroRNA‑744‑5p inhibits glioblastoma malignancy by suppressing replication factor C subunit 2

Fei Fan, Dongxiao Yao, Pengfei Yan, Xiaobing Jiang, Jie Hu
Article Number: 608
Published online on: 15 June 2021

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Article Open Access

Exosome‑derived microRNA‑433 inhibits tumorigenesis through incremental infiltration of CD4 and CD8 cells in non‑small cell lung cancer

Boyang Liu, Ruiping Zhang, Yungang Zhu, Ruisheng Hao
Article Number: 607
Published online on: 15 June 2021

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Article Open Access

Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression

Lei Yu, Jie Liu, Tang-De Zhang, Xiu-Fen Zheng, Dong-Lan Luo, Wei-Liang Zhu, Xian-Wen Qiu, Lin-Lang Guo
Article Number: 606
Published online on: 15 June 2021

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Article Open Access

Role of betulinic acid derivative SH‑479 in triple negative breast cancer and bone microenvironment

Liang Tang, Shu Jun Lv, Zhipeng Wu, Ming Qian, Yuduo Xu, Xin Gao, Tao Wang, Wen Guo, Tianhui Hou, Xiu Li, Zhenxi Li, Jian Zhao, Jianru Xiao, Haifeng Wei
Article Number: 605
Published online on: 15 June 2021

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Article Open Access

lncRNA MT1JP‑overexpression abolishes the silencing of PTEN by miR‑32 in hepatocellular carcinoma

Shuhua Zhang, Jianqun Xu, Qing Chen, Fan Zhang, Hongjuan Wang, Hongrong Guo
Article Number: 604
Published online on: 15 June 2021

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Article Open Access

Palbociclib induces cell senescence and apoptosis of gastric cancer cells by inhibiting the Notch pathway

Hengtai Bi, Juan Shang, Xiao Zou, Jing Xu, Yumei Han
Article Number: 603
Published online on: 10 June 2021

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Review Open Access

Roles of circular RNAs in colorectal cancer (Review)

Mingying Zhang, Shubin Wang
Article Number: 602
Published online on: 10 June 2021

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Article Open Access

P4HA2 promotes cell proliferation and migration in glioblastoma

Yuying Wu, Xunrui Zhang, Jue Wang, Ruijie Ji, Lei Zhang, Jianbing Qin, Meiling Tian, Guohua Jin, Xinhua Zhang
Article Number: 601
Published online on: 10 June 2021

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Retraction Open Access

[Retracted] miR‑215 functions as a tumor suppressor and directly targets ZEB2 in human non‑small cell lung cancer

Yan Hou, Junwen Zhen, Xiaodong Xu, Kun Zhen, Bin Zhu, Rui Pan, Chidong Zhao
Article Number: 600
Published online on: 10 June 2021

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Correction Open Access

[Corrigendum] HIF‑1α promotes ZEB1 expression and EMT in a human bladder cancer lung metastasis animal model

Jianning Zhu, Zhixin Huang, Mengzhao Zhang, Weiyi Wang, Hua Liang, Jin Zeng, Kaijie Wu, Xinyang Wang, Jer-Tsong Hsieh, Peng Guo, Jinhai Fan
Article Number: 599
Published online on: 10 June 2021

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Article Open Access

Gene expression of cytokinesis regulators PRC1, KIF14 and CIT has no prognostic role in colorectal and pancreatic cancer

Vojtech Hanicinec, Veronika Brynychova, Jachym Rosendorf, Richard Palek, Vaclav Liska, Martin Oliverius, Zdenek Kala, Beatrice Mohelnikova‑Duchonova, Ivona Krus, Pavel Soucek
Article Number: 598
Published online on: 09 June 2021

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Article Open Access

Artesunate combined with verteporfin inhibits uveal melanoma by regulation of the MALAT1/yes‑associated protein signaling pathway

Xudong Jiu, Yang Liu, Jin Wen
Article Number: 597
Published online on: 09 June 2021

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Review Open Access

Management of myxoid liposarcoma of the extremity (Review)

Yehia Tfayli, Ahmad Baydoun, Ahmad Salaheddine Naja, Said Saghieh
Article Number: 596
Published online on: 09 June 2021

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Article Open Access

MicroRNA profiles in five pairs of early gastric cancer tissues and adjacent non‑cancerous tissues

Yuan Liang, Yongxun Zhao, Longquan Li, Hui Wei, Taobi Huang, Huiyun Zhang, Xia Chen, Heng Yun, Weiming Sun, Yuping Wang
Article Number: 595
Published online on: 07 June 2021

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Article Open Access

Next‑generation sequencing‑based identification of EGFR and NOTCH2 complementary mutations in non‑small cell lung cancer

Lin Niu, Chunyan Dang, Lin Li, Na Guo, Ying Xu, Xiangling  Li, Qian Xu, Luyang Cheng, Li Zhang, Lei Liu
Article Number: 594
Published online on: 07 June 2021

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Article

Long non‑coding RNAs XIST and MALAT1 hijack the PD‑L1 regulatory signaling pathway in breast cancer subtypes

Amany Samir, Reda Abdel Tawab, Hend M. El Tayebi
Article Number: 593
Published online on: 07 June 2021

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Correction Open Access

[Corrigendum] Pediatric haematopoiesis and related malignancies (Review)

Mingwei Jin, Shumei Xu, Qi An
Article Number: 592
Published online on: 07 June 2021

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Article Open Access

MicroRNA‑4491 enhances cell proliferation and inhibits cell apoptosis in non‑small cell lung cancer via targeting TRIM7

Fei Han, Gang Chen, Yi Guo, Bo Li, Yanlong Sun, Xiangqian Qi, Hanji Tian, Xinfei Zhao, Hongguang Zhang
Article Number: 591
Published online on: 07 June 2021

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Article Open Access

IGF2 is a potential factor in RAI‑refractory differentiated thyroid cancer

Thomas Crezee, Marika H. Tesselaar, Martin Jaeger, Katrin Rabold, Willem E. Corver, Hans Morreau, Adriana C.H. Van Engen‑Van Grunsven, Jan W.A. Smit, Romana T. Netea‑Maier, Theo S. Plantinga
Article Number: 590
Published online on: 06 June 2021

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Review Open Access

C1GALT1 in health and disease (Review)

Xiaojie Sun, Mengru Zhan, Xun Sun, Wanqi Liu, Xiangwei Meng
Article Number: 589
Published online on: 06 June 2021

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Article Open Access

Combined effects of low‑dose gambogic acid and NaI131 in drug‑resistant non‑small cell lung cancer cells

Jing Huang, Xiao-Li Zhu, Ying Wu, Shu-Hua Han, Yan Xie, Su-Fang Yang, Ming Ding, Ping-Sheng Chen
Article Number: 588
Published online on: 04 June 2021

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Article Open Access

CXCR4 is a prognostic marker that inhibits the invasion and migration of gastric cancer by regulating VEGF expression

Gaoyang Chen, Zhen Zhou, Jun Jin, Yan Zhou, Yanqing Liu, Weimin Wang
Article Number: 587
Published online on: 04 June 2021

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Article Open Access

Small interfering‑high mobility group A2 attenuates epithelial‑mesenchymal transition in thymic cancer cells via the Wnt/β‑catenin pathway Expression of Concern in /10.3892/ol.2025.15222

Sheng Tan, Jili Chen
Article Number: 586
Published online on: 03 June 2021

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Article Open Access

si‑MALAT1 attenuates thymic cancer cell proliferation and promotes apoptosis via the miR‑145‑5p/HMGA2 pathway

Sheng Tan, Jili Chen
Article Number: 585
Published online on: 03 June 2021

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Article Open Access

Effect of BRAF‑mediated PI3K/Akt/mTOR pathway on biological characteristics and chemosensitivity of NSCLC A549/DDP cells

Bingnan Ren, Hongtao Liu, Yupeng Yang, Yufei Lian
Article Number: 584
Published online on: 03 June 2021

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Article Open Access

Clinical value of microRNA‑135a and MMP‑13 in colon cancer

Xinjun Zhou, Dong Yang, Xiping Ding, Peisheng Xu
Article Number: 583
Published online on: 03 June 2021

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Article Open Access

Treatment with lentiviral vectors encoding shRNA against interleukin 10 modulates the immunosuppressive activity of murine colon carcinoma‑associated myeloid‑derived suppressor cells

Natalia Anger‑Góra, Katarzyna Węgierek‑Ciura, Agnieszka Szczygieł, Jagoda Mierzejewska, Elżbieta Pajtasz‑Piasecka, Joanna Rossowska
Article Number: 582
Published online on: 02 June 2021

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Article

Sphingosine kinases are involved in the regulation of all‑trans retinoic acid sensitivity of K562 chronic myeloid leukemia cells

Defu Sun, Siping Wang
Article Number: 581
Published online on: 02 June 2021

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Article Open Access

miR‑497 inhibits proliferation and invasion in triple‑negative breast cancer cells via YAP1

Yuan Li, Kaiyao Hua, Jiali Jin, Lin Fang
Article Number: 580
Published online on: 02 June 2021

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Article Open Access

Decreased microRNA‑768‑3p expression indicates a poor prognosis in patients with breast cancer and promotes breast cancer cell viability, migration and invasion

Yanhua Zhou, Ying Wang, Lili Wang, Jing Zhang, Xin Liu
Article Number: 579
Published online on: 02 June 2021

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Article Open Access

LINC00857 promotes cell proliferation and migration in colorectal cancer by interacting with YTHDC1 and stabilizing SLC7A5

Shu Tang, Qi Liu, Ming Xu
Article Number: 578
Published online on: 02 June 2021

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Article

Long non‑coding RNA SNHG8 promotes autophagy as a ceRNA to upregulate ATG7 by sponging microRNA‑588 in colorectal cancer

Chi He, Yi Fu, Yan Chen, Xiquan Li
Article Number: 577
Published online on: 02 June 2021

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Article Open Access

OLA1 is a potential prognostic molecular biomarker for endometrial cancer and promotes tumor progression

Yanqi Dong, Aiqi Yin, Caiqu Xu, Huiping Jiang, Qinghai Wang, Wenjuan Wu, Suiqun Guo
Article Number: 576
Published online on: 02 June 2021

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Correction Open Access

[Corrigendum] GATA3 is downregulated in HCC and accelerates HCC aggressiveness by transcriptionally inhibiting slug expression

Zhuoliang Zhang, Xingliang Fang, Guilin Xie, Jinlong Zhu
Article Number: 575
Published online on: 02 June 2021

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Retraction Open Access

[Retracted] MicroRNA‑30a‑5p suppresses proliferation, invasion and tumor growth of hepatocellular cancer cells via targeting FOXA1

Shuliang Zhang, Qin Liu, Qi Zhang, Ling Liu
Article Number: 574
Published online on: 02 June 2021

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Correction Open Access

[Corrigendum] Novel technical modifications of hand‑assisted laparoscopic dissection of a large obturator mass: A case report and literature review

Jun Zhang, Peng Zhong, Haipeng Tong, Jun Jiang, Dali Tong
Article Number: 573
Published online on: 02 June 2021

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Retraction Open Access

[Retracted] MicroRNA‑423‑3p promotes glioma growth by targeting PANX2

Jing Xu, Jian He, He Huang, Renjun Peng, Jian Xi
Article Number: 572
Published online on: 02 June 2021

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Retraction Open Access

[Retracted] EZH2 inhibition promotes methyl jasmonate‑induced apoptosis of human colorectal cancer through the Wnt/β‑catenin pathway

Yao Wang, Li Fan, Chunguo Cui, Yongkun Wang, Tingting Liang
Article Number: 571
Published online on: 02 June 2021

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Article Open Access

Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Article Open Access

Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Article Open Access

Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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Article Open Access

TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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Review Open Access

From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Review Open Access

Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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