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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2021 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Targeting FHL2‑E‑cadherin axis by miR‑340‑5p attenuates colon cancer cell migration and invasion

Anwar Algaber, Raed Madhi, Avin Hawez, Carl-Fredrik Rönnow, Milladur Rahman
Article Number: 637
Published online on: 03 July 2021

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Review Open Access

Management of patients with chronic lymphocytic leukemia during the SARS‑CoV‑2 pandemic (Review)

Romeo Gabriel Mihaila
Article Number: 636
Published online on: 03 July 2021

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Article Open Access

Dose distribution effects of spot‑scanning proton beam therapy equipped with a multi‑leaf collimator for pediatric brain tumors

Nobuyoshi Fukumitsu, Tomohiro Yamashita, Masayuki Mima, Yusuke Demizu, Takeshi Suzuki, Toshinori Soejima
Article Number: 635
Published online on: 01 July 2021

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Article Open Access

Calponin 3 suppresses proliferation, migration and invasion of non‑small cell lung cancer cells

Chenglin Yang, Shiping Zhu, Weifeng Feng, Xuexin Chen
Article Number: 634
Published online on: 01 July 2021

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Article Open Access

Efficient pre‑treatment for pancreatic cancer using chloroquine‑loaded nanoparticles targeting pancreatic stellate cells

Sokichi Matsumoto, Kohei Nakata, Akiko Sagara, Weiyu Guan, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 633
Published online on: 01 July 2021

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Review

Advances in the role of autophagy in the development of retinoblastoma (Review)

Teng Wan, Mingyuan Fu, Zhuan Wu, Xue Gao, Shouhong Zhou
Article Number: 632
Published online on: 01 July 2021

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Article Open Access

Rosmanol induces breast cancer cells apoptosis by regulating PI3K/AKT and STAT3/JAK2 signaling pathways

Dongjun Jiang, Jiaqi Xu, Sitong Liu, Moussa Ide Nasser, Wei Wei, Tianjiao Mao, Xintong Liu, Xiaopan Zou, Jiang Li, Xiaomeng Li
Article Number: 631
Published online on: 01 July 2021

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Article Open Access

HSP60‑knockdown suppresses proliferation in colorectal cancer cells via activating the adenine/AMPK/mTOR signaling pathway

Jianying Guo, Songbiao Zhu, Haiteng Deng, Renhua Xu
Article Number: 630
Published online on: 01 July 2021

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Article

Pigment epithelium‑derived factor inhibits advanced glycation end product‑induced proliferation, VEGF and MMP‑9 expression in breast cancer cells via interaction with laminin receptor

Shiori Tsuruhisa, Takanori Matsui, Yoshinori Koga, Ami Sotokawauchi, Minoru Yagi, Sho-Ichi Yamagishi
Article Number: 629
Published online on: 30 June 2021

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Article Open Access

Aqueous extracts of Sanghuangporus vaninii induce S‑phase arrest and apoptosis in human melanoma A375 cells

Taihen Yu, Shi Zhong, Yuqing Sun, Haiyan Sun, Weiguo Chen, Yougui Li, Jianxun Zhu, Longxi Lu, Jinxi Huo
Article Number: 628
Published online on: 30 June 2021

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Article Open Access

Suppression of miR‑106a‑5p expression inhibits tumorigenesis via increasing CELF‑2 expression in spinal cord glioma

Hao Xu, Fei Wang, Lin Wang
Article Number: 627
Published online on: 30 June 2021

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Article Open Access

MicroRNA‑203‑3p inhibits the proliferation, invasion and migration of pancreatic cancer cells by downregulating fibroblast growth factor 2

Xi-Feng Fu, Hai-Chao Zhao, Chuan-Li Yang, Chang-Zhou Chen, Kang Wang, Fei Gao, Yang-Zhang Tian, Hao-Liang Zhao
Article Number: 626
Published online on: 30 June 2021

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Article Open Access

Association between cellular immune response and spleen weight in mice with hepatocellular carcinoma

Wei Jiang, Yu Li, Shuqun Zhang, Guangyao Kong, Zongfang Li
Article Number: 625
Published online on: 30 June 2021

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Article Open Access

lncRNA LOXL1‑AS1 promotes liver cancer cell proliferation and migration by regulating the miR‑377‑3p/NFIB axis

Wei Yu, Yong Dai
Article Number: 624
Published online on: 29 June 2021

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Article Open Access

Comprehensive serum and tissue microRNA profiling in dedifferentiated liposarcoma

Isaku Kohama, Naofumi Asano, Juntaro Matsuzaki, Yusuke Yamamoto, Tomofumi Yamamoto, Ryou-U Takahashi, Eisuke Kobayashi, Satoko Takizawa, Hiromi Sakamoto, Ken Kato, Hiroyuki Fujimoto, Hirotaka Chikuda, Akira Kawai, Takahiro Ochiya
Article Number: 623
Published online on: 29 June 2021

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Article Open Access

In vitro assessment of the efficiency of the PIM‑1 kinase pharmacological inhibitor as a potential treatment for Burkitt's lymphoma

Mona Alsubaie, Sabine Matou‑Nasri, Abdullah Aljedai, Ahmed  Alaskar, Hamad Al‑Eidi, Sarah A. Albabtain, Khawlah E. Aldilaijan, Manal Alsayegh, Ibrahim B. Alabdulkareem
Article Number: 622
Published online on: 29 June 2021

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Article Open Access

Effects of lncRNA ANRIL‑knockdown on the proliferation, apoptosis and cell cycle of gastric cancer cells

Xueqian Hu, Ting Lou, Chunying Yuan, Yongsheng Wang, Xiaolong Tu, Yi Wang, Tingsu Zhang
Article Number: 621
Published online on: 28 June 2021

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Article

Mammospheres of letrozole-resistant breast cancer cells enhance breast cancer aggressiveness

Jankiben R. Patel, Karen M. Gallegos, Rashidra R. Walker, A. Michael Davidson, Ian Davenport, Syreeta L. Tilghman
Article Number: 620
Published online on: 28 June 2021

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Article Open Access

hsa_circ_0060975 is highly expressed and predicts a poor prognosis in gastric cancer

Peng Xu, Xiaolan Xu, Lixiang Zhang, Zhengnan Li, Jianjun Qiang, Jie Yao, Aman Xu
Article Number: 619
Published online on: 24 June 2021

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Article Open Access

Diversity and shared T‑cell receptor repertoire analysis in esophageal squamous cell carcinoma

Tomoya Sudo, Akihiko Kawahara, Kazuo Ishi, Atsushi Mizoguchi, Sachiko Nagasu, Masashi Nakagawa, Masahiro Fujisaki, Haruhiro Hino, Kouhei Saisho, Hideaki Kaku, Satoru Matono, Naoki Mori, Jun Akiba, Akira Yamada, Yoshito Akagi
Article Number: 618
Published online on: 24 June 2021

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Article

MicroRNA‑148a‑3p inhibits the proliferation of cervical cancer cells by regulating the expression levels of DNMT1 and UTF1

Qing Chen, Yidong Wang, Huimin Dang, Xiaoling Wu
Article Number: 617
Published online on: 24 June 2021

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Article Open Access

Pseudogene legumain promotes thyroid carcinoma progression via the microRNA‑495/autophagy pathway

Jie Sun, Yicheng Peng, Jianxia Liu, Hao Zhou, Liang Sun, Qin He, Enqiao Yu
Article Number: 616
Published online on: 24 June 2021

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Article Open Access

Metformin suppresses breast cancer growth via inhibition of cyclooxygenase‑2

Bin Shi, Xinyu Hu, Huimin He, Wenzheng Fang
Article Number: 615
Published online on: 23 June 2021

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Article Open Access

Diagnostic potential of extracellular vesicle‑associated microRNA‑10b and tumor markers for lung adenocarcinoma

Guangda Yuan, Hongya Xie, Tengteng Wei, Donglin Zhu, Chuanyu Zhang, Yong Yang
Article Number: 614
Published online on: 23 June 2021

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Article Open Access

PD‑1 blockade enhances cytokine‑induced killer cell‑mediated cytotoxicity in B‑cell non‑Hodgkin lymphoma cell lines

Yutao Li, Amit Sharma, Maurits W.J.R. Bloemendal, Roland Schmidt‑Wolf, Miroslaw Kornek, Ingo G.H. Schmidt‑Wolf
Article Number: 613
Published online on: 23 June 2021

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Retraction Open Access

[Retracted] miR‑154 inhibits migration and invasion of human non‑small cell lung cancer by targeting ZEB2

Xingyu Lin, Zhiguang Yang, Peng Zhang, Yunpeng Liu, Guoguang Shao
Article Number: 612
Published online on: 18 June 2021

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Correction Open Access

[Corrigendum] Circulating extracellular vesicle‑encapsulated microRNA as screening biomarkers for intraductal papillary mucinous neoplasm

Yuki Sato, Rei Suzuki, Tadayuki Takagi, Mitsuru Sugimoto, Hiromasa Ohira
Article Number: 611
Published online on: 17 June 2021

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Article Open Access

Targeting glioma cells by antineoplastic activity of reversine

Camila Hirakata, Keli Lima, Bruna Oliveira De Almeida, Lívia Bassani Lins De Miranda, Katharine Gurgel Dias Florêncio, Luciana Costa Furtado, Leticia Veras Costa-Lotufo, João Agostinho Machado-Neto
Article Number: 610
Published online on: 15 June 2021

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Article Open Access

Melatonin inhibits gallbladder cancer cell migration and invasion via ERK‑mediated induction of epithelial‑to‑mesenchymal transition

Hongwei Tang, Xiaoyi Shi, Pengfei Zhu, Wenzhi Guo, Jie Li, Bing Yan, Shuijun Zhang
Article Number: 609
Published online on: 15 June 2021

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Article Open Access

MicroRNA‑744‑5p inhibits glioblastoma malignancy by suppressing replication factor C subunit 2

Fei Fan, Dongxiao Yao, Pengfei Yan, Xiaobing Jiang, Jie Hu
Article Number: 608
Published online on: 15 June 2021

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Article Open Access

Exosome‑derived microRNA‑433 inhibits tumorigenesis through incremental infiltration of CD4 and CD8 cells in non‑small cell lung cancer

Boyang Liu, Ruiping Zhang, Yungang Zhu, Ruisheng Hao
Article Number: 607
Published online on: 15 June 2021

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Article Open Access

Decreased TMEM40 expression is associated with malignant behavior of cutaneous squamous cell carcinoma and inhibits tumor progression

Lei Yu, Jie Liu, Tang-De Zhang, Xiu-Fen Zheng, Dong-Lan Luo, Wei-Liang Zhu, Xian-Wen Qiu, Lin-Lang Guo
Article Number: 606
Published online on: 15 June 2021

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Article Open Access

Role of betulinic acid derivative SH‑479 in triple negative breast cancer and bone microenvironment

Liang Tang, Shu Jun Lv, Zhipeng Wu, Ming Qian, Yuduo Xu, Xin Gao, Tao Wang, Wen Guo, Tianhui Hou, Xiu Li, Zhenxi Li, Jian Zhao, Jianru Xiao, Haifeng Wei
Article Number: 605
Published online on: 15 June 2021

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Article Open Access

lncRNA MT1JP‑overexpression abolishes the silencing of PTEN by miR‑32 in hepatocellular carcinoma

Shuhua Zhang, Jianqun Xu, Qing Chen, Fan Zhang, Hongjuan Wang, Hongrong Guo
Article Number: 604
Published online on: 15 June 2021

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Article Open Access

Palbociclib induces cell senescence and apoptosis of gastric cancer cells by inhibiting the Notch pathway

Hengtai Bi, Juan Shang, Xiao Zou, Jing Xu, Yumei Han
Article Number: 603
Published online on: 10 June 2021

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Review Open Access

Roles of circular RNAs in colorectal cancer (Review)

Mingying Zhang, Shubin Wang
Article Number: 602
Published online on: 10 June 2021

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Article Open Access

P4HA2 promotes cell proliferation and migration in glioblastoma

Yuying Wu, Xunrui Zhang, Jue Wang, Ruijie Ji, Lei Zhang, Jianbing Qin, Meiling Tian, Guohua Jin, Xinhua Zhang
Article Number: 601
Published online on: 10 June 2021

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Retraction Open Access

[Retracted] miR‑215 functions as a tumor suppressor and directly targets ZEB2 in human non‑small cell lung cancer

Yan Hou, Junwen Zhen, Xiaodong Xu, Kun Zhen, Bin Zhu, Rui Pan, Chidong Zhao
Article Number: 600
Published online on: 10 June 2021

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Correction Open Access

[Corrigendum] HIF‑1α promotes ZEB1 expression and EMT in a human bladder cancer lung metastasis animal model

Jianning Zhu, Zhixin Huang, Mengzhao Zhang, Weiyi Wang, Hua Liang, Jin Zeng, Kaijie Wu, Xinyang Wang, Jer-Tsong Hsieh, Peng Guo, Jinhai Fan
Article Number: 599
Published online on: 10 June 2021

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Article Open Access

Gene expression of cytokinesis regulators PRC1, KIF14 and CIT has no prognostic role in colorectal and pancreatic cancer

Vojtech Hanicinec, Veronika Brynychova, Jachym Rosendorf, Richard Palek, Vaclav Liska, Martin Oliverius, Zdenek Kala, Beatrice Mohelnikova‑Duchonova, Ivona Krus, Pavel Soucek
Article Number: 598
Published online on: 09 June 2021

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Article Open Access

Artesunate combined with verteporfin inhibits uveal melanoma by regulation of the MALAT1/yes‑associated protein signaling pathway

Xudong Jiu, Yang Liu, Jin Wen
Article Number: 597
Published online on: 09 June 2021

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Review Open Access

Management of myxoid liposarcoma of the extremity (Review)

Yehia Tfayli, Ahmad Baydoun, Ahmad Salaheddine Naja, Said Saghieh
Article Number: 596
Published online on: 09 June 2021

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Article Open Access

MicroRNA profiles in five pairs of early gastric cancer tissues and adjacent non‑cancerous tissues

Yuan Liang, Yongxun Zhao, Longquan Li, Hui Wei, Taobi Huang, Huiyun Zhang, Xia Chen, Heng Yun, Weiming Sun, Yuping Wang
Article Number: 595
Published online on: 07 June 2021

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Article Open Access

Next‑generation sequencing‑based identification of EGFR and NOTCH2 complementary mutations in non‑small cell lung cancer

Lin Niu, Chunyan Dang, Lin Li, Na Guo, Ying Xu, Xiangling  Li, Qian Xu, Luyang Cheng, Li Zhang, Lei Liu
Article Number: 594
Published online on: 07 June 2021

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Article

Long non‑coding RNAs XIST and MALAT1 hijack the PD‑L1 regulatory signaling pathway in breast cancer subtypes

Amany Samir, Reda Abdel Tawab, Hend M. El Tayebi
Article Number: 593
Published online on: 07 June 2021

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Correction Open Access

[Corrigendum] Pediatric haematopoiesis and related malignancies (Review)

Mingwei Jin, Shumei Xu, Qi An
Article Number: 592
Published online on: 07 June 2021

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Article Open Access

MicroRNA‑4491 enhances cell proliferation and inhibits cell apoptosis in non‑small cell lung cancer via targeting TRIM7

Fei Han, Gang Chen, Yi Guo, Bo Li, Yanlong Sun, Xiangqian Qi, Hanji Tian, Xinfei Zhao, Hongguang Zhang
Article Number: 591
Published online on: 07 June 2021

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Article Open Access

IGF2 is a potential factor in RAI‑refractory differentiated thyroid cancer

Thomas Crezee, Marika H. Tesselaar, Martin Jaeger, Katrin Rabold, Willem E. Corver, Hans Morreau, Adriana C.H. Van Engen‑Van Grunsven, Jan W.A. Smit, Romana T. Netea‑Maier, Theo S. Plantinga
Article Number: 590
Published online on: 06 June 2021

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Review Open Access

C1GALT1 in health and disease (Review)

Xiaojie Sun, Mengru Zhan, Xun Sun, Wanqi Liu, Xiangwei Meng
Article Number: 589
Published online on: 06 June 2021

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Article Open Access

Combined effects of low‑dose gambogic acid and NaI131 in drug‑resistant non‑small cell lung cancer cells

Jing Huang, Xiao-Li Zhu, Ying Wu, Shu-Hua Han, Yan Xie, Su-Fang Yang, Ming Ding, Ping-Sheng Chen
Article Number: 588
Published online on: 04 June 2021

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Article Open Access

CXCR4 is a prognostic marker that inhibits the invasion and migration of gastric cancer by regulating VEGF expression

Gaoyang Chen, Zhen Zhou, Jun Jin, Yan Zhou, Yanqing Liu, Weimin Wang
Article Number: 587
Published online on: 04 June 2021

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Article Open Access

Small interfering‑high mobility group A2 attenuates epithelial‑mesenchymal transition in thymic cancer cells via the Wnt/β‑catenin pathway Expression of Concern in /10.3892/ol.2025.15222

Sheng Tan, Jili Chen
Article Number: 586
Published online on: 03 June 2021

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Article Open Access

si‑MALAT1 attenuates thymic cancer cell proliferation and promotes apoptosis via the miR‑145‑5p/HMGA2 pathway

Sheng Tan, Jili Chen
Article Number: 585
Published online on: 03 June 2021

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Article Open Access

Effect of BRAF‑mediated PI3K/Akt/mTOR pathway on biological characteristics and chemosensitivity of NSCLC A549/DDP cells

Bingnan Ren, Hongtao Liu, Yupeng Yang, Yufei Lian
Article Number: 584
Published online on: 03 June 2021

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Article Open Access

Clinical value of microRNA‑135a and MMP‑13 in colon cancer

Xinjun Zhou, Dong Yang, Xiping Ding, Peisheng Xu
Article Number: 583
Published online on: 03 June 2021

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Article Open Access

Treatment with lentiviral vectors encoding shRNA against interleukin 10 modulates the immunosuppressive activity of murine colon carcinoma‑associated myeloid‑derived suppressor cells

Natalia Anger‑Góra, Katarzyna Węgierek‑Ciura, Agnieszka Szczygieł, Jagoda Mierzejewska, Elżbieta Pajtasz‑Piasecka, Joanna Rossowska
Article Number: 582
Published online on: 02 June 2021

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Article

Sphingosine kinases are involved in the regulation of all‑trans retinoic acid sensitivity of K562 chronic myeloid leukemia cells

Defu Sun, Siping Wang
Article Number: 581
Published online on: 02 June 2021

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Article Open Access

miR‑497 inhibits proliferation and invasion in triple‑negative breast cancer cells via YAP1

Yuan Li, Kaiyao Hua, Jiali Jin, Lin Fang
Article Number: 580
Published online on: 02 June 2021

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Article Open Access

Decreased microRNA‑768‑3p expression indicates a poor prognosis in patients with breast cancer and promotes breast cancer cell viability, migration and invasion

Yanhua Zhou, Ying Wang, Lili Wang, Jing Zhang, Xin Liu
Article Number: 579
Published online on: 02 June 2021

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Article Open Access

LINC00857 promotes cell proliferation and migration in colorectal cancer by interacting with YTHDC1 and stabilizing SLC7A5

Shu Tang, Qi Liu, Ming Xu
Article Number: 578
Published online on: 02 June 2021

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Article

Long non‑coding RNA SNHG8 promotes autophagy as a ceRNA to upregulate ATG7 by sponging microRNA‑588 in colorectal cancer

Chi He, Yi Fu, Yan Chen, Xiquan Li
Article Number: 577
Published online on: 02 June 2021

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Article Open Access

OLA1 is a potential prognostic molecular biomarker for endometrial cancer and promotes tumor progression

Yanqi Dong, Aiqi Yin, Caiqu Xu, Huiping Jiang, Qinghai Wang, Wenjuan Wu, Suiqun Guo
Article Number: 576
Published online on: 02 June 2021

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Correction Open Access

[Corrigendum] GATA3 is downregulated in HCC and accelerates HCC aggressiveness by transcriptionally inhibiting slug expression

Zhuoliang Zhang, Xingliang Fang, Guilin Xie, Jinlong Zhu
Article Number: 575
Published online on: 02 June 2021

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Retraction Open Access

[Retracted] MicroRNA‑30a‑5p suppresses proliferation, invasion and tumor growth of hepatocellular cancer cells via targeting FOXA1

Shuliang Zhang, Qin Liu, Qi Zhang, Ling Liu
Article Number: 574
Published online on: 02 June 2021

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Correction Open Access

[Corrigendum] Novel technical modifications of hand‑assisted laparoscopic dissection of a large obturator mass: A case report and literature review

Jun Zhang, Peng Zhong, Haipeng Tong, Jun Jiang, Dali Tong
Article Number: 573
Published online on: 02 June 2021

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Retraction Open Access

[Retracted] MicroRNA‑423‑3p promotes glioma growth by targeting PANX2

Jing Xu, Jian He, He Huang, Renjun Peng, Jian Xi
Article Number: 572
Published online on: 02 June 2021

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Retraction Open Access

[Retracted] EZH2 inhibition promotes methyl jasmonate‑induced apoptosis of human colorectal cancer through the Wnt/β‑catenin pathway

Yao Wang, Li Fan, Chunguo Cui, Yongkun Wang, Tingting Liang
Article Number: 571
Published online on: 02 June 2021

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Journal Cover
November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Ivonescimab combined with radiotherapy in the treatment of advanced lung adenocarcinoma with high expression of PD‑L1: A case report

Qi Zhou, Bo Yang, Hongyi Cai, Jun Jiang, Rong Chen
Article Number: 538
Published online on: 02 October 2026

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Article Open Access

Association between antidepressant exposure and prognosis in breast cancer: A systematic review and meta‑analysis

Qisong Chen, Yihan Shen, Xiaoming Zhang, Ting Jiang, Shiyan Zhang, Xinyan Yu, Feng Hong
Article Number: 537
Published online on: 02 October 2026

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Review Open Access

Brain‑derived neurotrophic factor in solid tumor angiogenesis and neurovascular‑immune interactions (Review)

Guoqing Zhu, Dianliang Zhang, Hao Wang, Sen Yan, Mingchao Ni, Shangkun Ning, Chong Wang, Mei Liu, Jibing Liu
Article Number: 536
Published online on: 01 October 2026

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Article Open Access

hnRNPC promotes oral squamous cell carcinoma progression via N6‑methyladenosine‑dependent stabilization of BCAT1 to enhance branched‑chain amino acid metabolism

Zhixin Zhang, Xin Gao, Ting Han, Fei Chai, Menghui Gao, Yulin An
Article Number: 535
Published online on: 01 October 2026

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Expression of Concern Open Access

[Expression of Concern] Reduced migration of Ishikawa cells associated with downregulation of aquaporin‑5

Xiu Xiu Jiang, Kai Hong Xu, Jun Yan Ma, Yong Hong Tian, Xiao Yan Guo, Jun Lin, Rui Jin Wu
Article Number: 534
Published online on: 30 September 2026

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Case Report Open Access

A thoracic SMARCA4‑deficient undifferentiated tumor: A case report

Xiaocheng Wang, Miao Chen, Mingzhe Wang, Chengjun Ban, Lishan Zhang, Heng Zou, Hongwu Wang, Bing Yang
Article Number: 533
Published online on: 29 September 2026

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Case Report Open Access

Stage IIIB pulmonary sarcomatoid carcinoma treated with spatially fractionated radiotherapy combined with antiangiogenic therapy and sequential chemo‑immunotherapy: A case report

Zijian Qiu, Feng Xuan, Xi Mao, Peipei Yang, Xiaoping Zhu
Article Number: 532
Published online on: 29 September 2026

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Article Open Access

Single‑cell transcriptomics identifies PRDX1 and GPX4 as potential ferroptosis regulators and tumor microenvironment‑­related molecules in hepatocellular carcinoma

Zhou Zhang, Hui Chen, Chen Qian, Ningning Yang, Zijing Liu, Ruirui Yang
Article Number: 531
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Interferon‑α suppresses invasion and enhances cisplatin‑mediated apoptosis and autophagy in human osteosarcoma cells

Jun Zhao, Mingli Wang, Zeng Li, Jingxian Chen, Zongshen Yin, Jun Chang, Dongmei Gao, Shiping Wang
Article Number: 530
Published online on: 28 September 2026

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Article Open Access

KRT14 activated by transcription factor E2F1 promotes bladder cancer progression

Xingheng Chen, Sinan Liu, Xiaosong Zhang, Xiang Chen, Chenlu Wang
Article Number: 529
Published online on: 24 September 2026

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Review Open Access

Research progress of pancreatic cancer based on ferroptosis‑cuproptosis interaction (Review)

Wenqing Liu, Minglu Ding, Ruijiao Ji, Zhenmin Qiao, Ran Liu, Peijian Chen, Lantao Liu
Article Number: 528
Published online on: 24 September 2026

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Correction Open Access

[Corrigendum] Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

Xiaojing Lai, Qing Gu, Xia Zhou, Wei Feng, Xiao Lin, Yan He, Jinming Cao, Pengfei Liu, Huojun Zhang, Xiao Zheng
Article Number: 527
Published online on: 24 September 2026

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Case Report Open Access

Therapy‑related acute myeloid leukemia with a rare complex karyotype following first‑line therapy for small cell lung cancer: A case report

Lin Luo, Sha Yu
Article Number: 526
Published online on: 23 September 2026

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Article Open Access

Netupitant‑palonosetron combined with dexamethasone for preventing chemotherapy‑induced nausea and vomiting in high‑risk patients with colorectal cancer receiving moderately emetogenic chemotherapy: A retrospective study

Jiwen Fan, Wenjuan Lai, Boran Cheng, Meijing Chen, Jing Gao, Shubin Wang, Gangling Tong
Article Number: 525
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] Upregulation of H19 promotes invasion and induces epithelial‑to‑mesenchymal transition in esophageal cancer

Cheng Huang, Lihua Cao, Limin Qiu, Xiaoli Dai, Linwei Ma, Yingting Zhou, Huifen Li, Min Gao, Weiyong Li, Qing Zhang, Koulan Han, Hongzhen Lv
Article Number: 524
Published online on: 23 September 2026

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Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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Article Open Access

MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Article Open Access

Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Article Open Access

Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec-Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Article Open Access

Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Article Open Access

Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara-Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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Journal Cover
December-2026 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

Five‑fraction stereotactic body radiotherapy for prostate cancer in octogenarians and nonagenarians: A single‑institution retrospective cohort study

Atsuto Katano, Hideomi Yamashita
Article Number: 562
Published online on: 22 October 2026

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Article Open Access

Identification of SLC7A5 and transferrin as key ferroptosis modulators in triple‑negative breast cancer

Ruidi Liu, Xiao Cui, Bingyu Guo, Yiting Liu, Feng Lin, Zhiqiang Fu, Bing Xie
Article Number: 561
Published online on: 22 October 2026

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Article Open Access

PEG10/TRIB3 axis is associated with malignant behavior and Notch‑related signaling in oral squamous cell carcinoma cells

Jing Zhang, Ying Liu
Article Number: 560
Published online on: 22 October 2026

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Article Open Access

Diagnostic performance of a combined TAP, TAM, CA125 and CA153 panel for stage I breast cancer in patients with unilateral nipple discharge

Yingli Men, Ruiting Feng, Beibei Ye, Yahui Hu, Ping Wang, Jizhi Zhao, Yang Zheng, Hui Wang, Yinsen Song, Cong Ding
Article Number: 559
Published online on: 22 October 2026

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Correction Open Access

[Corrigendum] Individualized therapy based on the combination of mini‑PDX and NGS for a patient with metastatic AFP‑producing and HER‑2 amplified gastric cancer

Xiaodan Zhu, Xiaoqing Xu, Baonan Zhang, Yun Dong, Shixia Gong, Tingjie Gong, Feifei Zhang, Chunhui Jin
Article Number: 558
Published online on: 21 October 2026

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Article Open Access

Calycosin synergistically promotes ferroptosis in cervical cancer cells by inducing epithelial‑mesenchymal transition

Lei Zhang, Qiuyi Shen, Jingyi Zhu, Ping Wang, Wanhong Wei, Jie Zhou
Article Number: 557
Published online on: 19 October 2026

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Correction Open Access

[Corrigendum] Androgen deprivation therapy has no effect on Pim‑1 expression in a mouse model of prostate cancer

Jiang Wang, Gang Li, Bo Li, Hualin Song, Zhiqun Shang, Ning Jiang, Yuanjie Niu
Article Number: 556
Published online on: 19 October 2026

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Article Open Access

An interpretable machine‑learning model to predict moderate‑to‑severe acute radiation esophagitis following regional nodal irradiation for breast cancer

Bin He, Zhongchun Qi, Hengdi Zhang, Linling Li, Hua Li, Xinyun Zou, Yu Tan, Ling Zhang, Fangyuan Kong
Article Number: 555
Published online on: 16 October 2026

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Article Open Access

Anti‑neoplastic effects of Chrysanthemum indicum extract on a human hypopharyngeal squamous cell carcinoma cell line 

Ching-Wen Liu, Li-Ching Chang, Ting-Ting Lai, Hsiao-Chi Lai
Article Number: 554
Published online on: 16 October 2026

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Article Open Access

KAZALD1 upregulation predicts poor prognosis in epithelial ovarian cancer: Clinical validation and immune correlates

Ruru Zhao, Ye Hu, Jia Wang, Jingjing Lu, Guiqiang Du
Article Number: 553
Published online on: 15 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic effect of jolkinolide B and the mechanism of activity in breast cancer MDA‑MB‑231 cells

Chao Sun, Hongxia Cui, Hongyan Yang, Xiaohui Du, Liling Yue, Jicheng Liu, Yu Lin
Article Number: 552
Published online on: 14 October 2026

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Article Open Access

Optimal timing of thoracic radiotherapy with osimertinib in unresectable EGFR‑mutant non‑small cell lung cancer

Mengting Lai, Yanhua Zhou, Weili Yi, Jian Huang, Zhili Chen, Xin Yin, Li Qin, Dongning Huang
Article Number: 551
Published online on: 13 October 2026

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Article Open Access

Unveiling a dual‑pathway prognostic model: Integrating T cell‑related and ubiquitination‑related genes in lung adenocarcinoma

Shuang Zeng, Huidi Gao, Hongying Liang, Degang Zhang
Article Number: 550
Published online on: 13 October 2026

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Article Open Access

Supplementary value of primary tumor volume for prognostic stratification in patients with T3‑4 nasopharyngeal carcinoma: A retrospective cohort study

Hui Huang, Yusong Lu, Yingjie Ouyang, Min Pan, Xinyu Tang, Hongrui He, Tingfeng Zhang, Qi Gong, Chunqiao Chen, Qiuqiu Chen
Article Number: 549
Published online on: 13 October 2026

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Article

Safety of concurrent immune checkpoint inhibitor therapy during postoperative radiotherapy for triple‑negative breast cancer: A preliminary retrospective analysis

Gai Liang, Qu Zhang, Mengting Yuan, Guojun Yao, Feng Yuan
Article Number: 548
Published online on: 13 October 2026

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Expression of Concern Open Access

[Expression of Concern] Expression of L1 protein correlates with cluster of differentiation 24 and integrin β1 expression in gastrointestinal stromal tumors

Yue Du, Aihong Zhang, Zhongmin Jiang, Guowei Huang, Wenli Lu, Hesheng Wang
Article Number: 547
Published online on: 12 October 2026

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Article Open Access

Bulk and single‑cell analysis of FAM72D reveals its prognostic and functional relevance in hepatocellular carcinoma

Cuihao Zhao, Quliyang Yin, Jianfeng Yu, Weiqi Duan, Yufeng Li, Qian Jian
Article Number: 546
Published online on: 12 October 2026

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Article Open Access

Serum metabolomic signatures associated with gastric signet‑ring cell carcinoma: A dual‑platform mass spectrometry study

Huiling Cao, Shuwei Guo, Jinchang Li, Yuying Bian, Jianjiang Shen, Jia Wang, Fei Meng, Wenlu Sun, Qingmin Sun, Wanjian Gu
Article Number: 545
Published online on: 09 October 2026

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Case Report Open Access

Drug‑eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report

Yin Gao, Qiang Xu, Dongxu Kang, Longzhen Piao
Article Number: 544
Published online on: 08 October 2026

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Case Report Open Access

Unexpected favorable response of stage IV gastric adenocarcinoma to sintilimab combined with chemotherapy: A case report

Jian Han, Zhe Zhu, Liang Huang, Liang Zhuang, Lihong Zhang, Yixin Tong, Chao Zhang, Hanlin Mu, Huaping Xie
Article Number: 543
Published online on: 08 October 2026

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Correction Open Access

[Corrigendum] Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells

Yawei Shi, Yang Zhao, Nan Shao, Runyi Ye, Yin Lin, Ning Zhang, Wen Li, Yunjian Zhang, Shenming Wang
Article Number: 542
Published online on: 08 October 2026

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Article Open Access

Potential of clinical staging for long‑term prognosis prediction in pathological stage III gastric cancer

Naosuke Nakamichi, Hiroyuki Inoue, Takeshi Kubota, Toshiyuki Kosuga, Keiji Nishibeppu, Kazuya Takabatake, Shutaro Sumiyoshi, Junichi Hamada, Kento Kurashima, Hidemasa Kubo, Jun Kiuchi, Taisuke Imamura, Kenji Nanishi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Hitoshi Fujiwara, Toshiya Ochiai, Atsushi Shiozaki
Article Number: 541
Published online on: 07 October 2026

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Article Open Access

NOL11 is a novel prognostic biomarker associated with immune infiltration and tumor progression in hepatocellular carcinoma

Hong Xie, Shengnan Wang, Xiaoyan Sheng, Lei Ye
Article Number: 540
Published online on: 07 October 2026

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Correction Open Access

[Corrigendum] Emodin induces apoptosis of human breast cancer cells by modulating the expression of apoptosis‑related genes

Cong Zu, Mingdi Zhang, Hui Xue, Xiaopeng Cai, Lei Zhao, Anning He, Guangyuan Qin, Chunshu Yang, Xinyu Zheng
Article Number: 539
Published online on: 02 October 2026

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