Open Access

Vaginal yolk sac tumors in infants and children: A case report and literature review

  • Authors:
    • Zhongli Ma
    • Canyu Li
  • View Affiliations

  • Published online on: February 8, 2023     https://doi.org/10.3892/ol.2023.13706
  • Article Number: 120
  • Copyright: © Ma et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

A vaginal yolk sac tumor (YST) is a rare malignant germ cell tumor for infants and children, and it has been >50 years since the first case was reported. The treatment strategy has changed markedly in the past 50 years, from radical surgical treatment to conservative surgery combined with chemotherapy, and then to combined chemotherapy alone. The present study reports the case of a primary vaginal YST in a 13‑month‑old girl that was successfully treated by tumor resection combined with chemotherapy. The clinical symptoms, imaging features and treatment characteristics are described in detail, as well as the postoperative treatment. There was no local recurrence or metastasis for the 2 years of follow‑up to date. A literature review was also conducted to investigate the clinicopathological features, treatment and prognosis of this tumor. Overall, surgery combined with bleomycin, etoposide and carboplatin combination chemotherapy can be an effective option for vaginal YST.
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March-2023
Volume 25 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Ma Z and Ma Z: Vaginal yolk sac tumors in infants and children: A case report and literature review. Oncol Lett 25: 120, 2023
APA
Ma, Z., & Ma, Z. (2023). Vaginal yolk sac tumors in infants and children: A case report and literature review. Oncology Letters, 25, 120. https://doi.org/10.3892/ol.2023.13706
MLA
Ma, Z., Li, C."Vaginal yolk sac tumors in infants and children: A case report and literature review". Oncology Letters 25.3 (2023): 120.
Chicago
Ma, Z., Li, C."Vaginal yolk sac tumors in infants and children: A case report and literature review". Oncology Letters 25, no. 3 (2023): 120. https://doi.org/10.3892/ol.2023.13706