Open Access

Misdiagnosis of angioimmunoblastic T‑cell lymphoma: A case report

  • Authors:
    • Yan Li
    • Xiaohan Gao
    • Ling-Zhijie Kong
    • Jie Li
  • View Affiliations

  • Published online on: April 26, 2023     https://doi.org/10.3892/ol.2023.13836
  • Article Number: 250
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Angioimmunoblastic T‑cell lymphoma (AITL) is a specific subtype of peripheral T‑cell lymphoma that is challenging to diagnose due to the lack of specific pathological characteristics. This report describes the case of a 56‑year‑old man with Hodgkin lymphoma in whom the gene rearrangement results were positive for TCRβDB+Jβ1/2. Pathological and immunochemical examinations revealed a diagnosis of lymphoma that was a composite of AITL and focal classical Hodgkin lymphoma. Unfortunately, he died soon after the correct diagnosis was made. This case shows that a combination of immunohistochemistry and gene rearrangement analysis can increase the diagnostic accuracy for AITL. A review of the literature on the misdiagnosis of AITL indicates that this disease progresses rapidly with a high mortality rate. Our experience, in this case, highlights the need for early diagnosis.
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June-2023
Volume 25 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Li Y, Gao X, Kong L and Li J: Misdiagnosis of angioimmunoblastic T‑cell lymphoma: A case report. Oncol Lett 25: 250, 2023
APA
Li, Y., Gao, X., Kong, L., & Li, J. (2023). Misdiagnosis of angioimmunoblastic T‑cell lymphoma: A case report. Oncology Letters, 25, 250. https://doi.org/10.3892/ol.2023.13836
MLA
Li, Y., Gao, X., Kong, L., Li, J."Misdiagnosis of angioimmunoblastic T‑cell lymphoma: A case report". Oncology Letters 25.6 (2023): 250.
Chicago
Li, Y., Gao, X., Kong, L., Li, J."Misdiagnosis of angioimmunoblastic T‑cell lymphoma: A case report". Oncology Letters 25, no. 6 (2023): 250. https://doi.org/10.3892/ol.2023.13836