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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2023 Volume 25 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Stress granules affect the sensitivity of renal cancer cells to sorafenib by sequestering and stabilizing COX‑2 mRNA

Huiqi Dai, Guoli Wang, Wenmin Cao, Wei Qi, Wei Chen, Hongqian Guo
Article Number: 274
Published online on: 10 May 2023

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Article Open Access

Efficacy and safety of surufatinib in the treatment of advanced solid tumors: a systematic evaluation and meta‑analysis

Tianying Cai, Yonglang Cheng, Yichao Du, Peng Tan, Tongxi Li, Yifan Chen, Lin Gao, Wenguang Fu
Article Number: 273
Published online on: 10 May 2023

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Article Open Access

Association between Ki67 expression and therapeutic outcome in colon cancer

Qi Liu, Dongmei Ran, Liping Wang, Jiajun Feng, Wei Deng, Dongdong Mei, Yifan Peng, Changzheng Du
Article Number: 272
Published online on: 10 May 2023

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Article Open Access

Snail inhibits metastasis via regulation of E‑cadherin and is associated with prognosis in colorectal cancer

Weimin Wang, Jun Jin, Zhen Zhou, Yunfan Wang, Ke Min, Xin Zuo, Jiaping Jiang, Yan Zhou, Jun Shi
Article Number: 271
Published online on: 05 May 2023

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Case Report Open Access

Bladder metastasis from type 2 papillary renal cell carcinoma: A case report

Qinsong Zeng, Shuhang Luo, Linze Chen, Lingwu Chen, Junxing Chen
Article Number: 270
Published online on: 05 May 2023

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Article Open Access

Pretreatment fibrinogen levels are associated with survival outcome in patients with cancer using immunotherapy as a second‑line treatment

Rui Xu, Tao Yang, Bing Yan, Junhao You, Fang Li, Qiang Zuo
Article Number: 269
Published online on: 05 May 2023

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Article Open Access

Effect of arsenic trioxide plus etoposide, solumedrol, high‑dose cytarabine and cisplatin chemotherapy on the treatment of relapsed or refractory ALK+ anaplastic large cell lymphoma

Yi Ding, Huina Lu, Yan Dong, Bing Xiu, Aibin Liang, Wenjun Zhang
Article Number: 268
Published online on: 04 May 2023

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Article Open Access

The role of miRNA in colorectal cancer diagnosis: A pilot study

Maša Ždralević, Janja Raonić, Natasa Popovic, Ljiljana Vučković, Isidora Rovčanin Dragović, Batrić Vukčević, Vladimir Todorović, Filip Vukmirović, Flaviana Marzano, Apollonia Tullo, Nicoletta Guaragnella, Sergio Giannattasio, Miodrag Radunović
Article Number: 267
Published online on: 04 May 2023

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Review Open Access

CTHRC1, a novel gene with multiple functions in physiology, disease and solid tumors (Review)

Ya-Juan Liu, Jing Du, Jie Li, Xiao-Ping Tan, Qing Zhang
Article Number: 266
Published online on: 03 May 2023

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Review Open Access

Metabolic biomarkers in lung cancer screening and early diagnosis (Review)

Yongjie Xu, Xuesi Dong, Chao Qin, Fei Wang, Wei Cao, Jiang Li, Yiwen Yu, Liang Zhao, Fengwei Tan, Wanqing Chen, Ni Li, Jie He
Article Number: 265
Published online on: 03 May 2023

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Review Open Access

Complications after endoscopic submucosal dissection for early colorectal cancer (Review)

Jianhui Sun, Xinyuan Xie, Yangcheng Liu, Xianglin Hao, Gang Yang, Dan Zhang, Qiong Nan
Article Number: 264
Published online on: 03 May 2023

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Article Open Access

Efficacy of hypofractionated preoperative chemoradiotherapy in rectal cancer

Ick Joon Cho, Jae-Uk Jeong, Taek-Keun Nam, Yong-Hyub Kim, Ju-Young Song, Mee Sun Yoon, Sung-Ja Ahn, Shin Haeng Cho
Article Number: 263
Published online on: 03 May 2023

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Article

Clinical outcomes of immunotherapy continued beyond radiographic disease progression in older adult patients with advanced non‑small cell lung cancer

Eric K. Singhi, Frank Mott, Michelle Worst, Cheuk Hong Leung, J. Jack Lee, Brett Carter, Carolyn J. Presley, John V. Heymach, Mehmet Altan
Article Number: 262
Published online on: 03 May 2023

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Article Open Access

Distribution characteristics and clinical significance of infiltrating T cells in the tumor microenvironment of pancreatic cancer

Gen Sun, Zhengjiang Yang, Kang Fang, Yuanpeng Xiong, Shuju Tu, Siqing Yi, Weidong Xiao
Article Number: 261
Published online on: 02 May 2023

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Article Open Access

1,4,5,6,7,8‑Hexahydropyrido[4,3‑d]pyrimidine inhibits HepG2 cell proliferation, migration and invasion, and induces apoptosis through the upregulation of miR‑26b‑5p by targeting CDK8

Hanlin Luo, Yang Yang, Yanqiu Zhou, Xianyong Bai, Yun Hou
Article Number: 260
Published online on: 02 May 2023

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Article Open Access

Tumor‑infiltrating CD8+ T cells as a biomarker for chemotherapy efficacy in unresectable hepatocellular carcinoma

Akifumi Kuwano, Masayoshi Yada, Yoshiko Miyazaki, Kosuke Tanaka, Kazuki Kurosaka, Yoshihiro Ohishi, Akihide Masumoto, Kenta Motomura
Article Number: 259
Published online on: 28 April 2023

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Article Open Access

A novel prednisone premedication protocol significantly decreases infusion‑related reactions of rituximab in newly diagnosed diffuse large B‑cell lymphoma

Jianghua Ding, Zhaohui Leng, Hong Gu, Xiang Jing
Article Number: 258
Published online on: 28 April 2023

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Article Open Access

Predictive factors and a novel nomogram for recurrence of primary retroperitoneal liposarcoma: Comprehensive analysis of 128 cases

Zhi-Yuan Yu, Jing-Wang Gao, Na Liu, Si-Xin Zhou, Xu-Dong Zhao, Pei-Yu Li
Article Number: 257
Published online on: 28 April 2023

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Article Open Access

Association between the expression levels of ADAMTS16 and BMP2 and tumor budding in hepatocellular carcinoma

Di Jiang, Shaoshao Xu, Chuanpeng Zhang, Chuanbing Hu, Lei Li, Mingming Zhang, Haiyan Wu, Dongchang Yang, Yanrong Liu
Article Number: 256
Published online on: 27 April 2023

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Article Open Access

Detection of serum HE4 levels contributes to the diagnosis of lung cancer

Jun Li, Yuzhu Li, Lijing Huo, Ruyi Sun, Xiao Liu, Quan Gu, Anping Li, Sugui Han, Hongmei Liu, Yufeng Li, Yumin Zhang
Article Number: 255
Published online on: 27 April 2023

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Article

Morphological, clinical and molecular characteristics in ARID1a‑deficient microsatellite‑stable oesophageal adenocarcinoma

Jan Rehkaemper, Florian Gebauer, Bastian Ulmer, Simon Schallenberg, Julian Bork, Thomas Zander, Reinhard Buettner, Christiane Josephine Bruns, Wolfgang Schroeder, Alexander Quaas
Article Number: 254
Published online on: 26 April 2023

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Case Report Open Access

Characteristic contrast‑enhanced ultrasound findings of hepatic epithelioid haemangioendothelioma: A case report and literature review

Wen Tang, Yifan Niu, Yang Luo, Xiaojuan Ma
Article Number: 253
Published online on: 26 April 2023

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Case Report Open Access

Undifferentiated carcinoma with osteoclast‑like giant cells of the pancreas: A case report

Haifeng Ran, Guiqin Chen, Yulun He, Qiane Yu, Yuxin Xie, Junwei Liu, Heng Liu, Tijiang Zhang
Article Number: 252
Published online on: 26 April 2023

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Case Report Open Access

Primary follicular lymphoma of the uterine cervix: A case report

Alkis Matsas, Panagiotis Christopoulos, Charalampos Karachalios, Orestis Savranakis, Leonidas Marinos, Nikos F. Vlahos, Theodoros Panoskaltsis
Article Number: 251
Published online on: 26 April 2023

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Case Report Open Access

Misdiagnosis of angioimmunoblastic T‑cell lymphoma: A case report

Yan Li, Xiaohan Gao, Ling-Zhijie Kong, Jie Li
Article Number: 250
Published online on: 26 April 2023

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Case Report Open Access

A giant breast malignant solitary fibrous tumor: A rare case report and brief review

Yonghui Wang, Liquan Wang, Jinning Huang, Xiuping Liu, Huimin Sun, Xiaomei Sui, Xianglian Sun
Article Number: 249
Published online on: 26 April 2023

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Article Open Access

Nifuroxazide induces the apoptosis of human non‑small cell lung cancer cells through the endoplasmic reticulum stress PERK signaling pathway

Deliang Li, Liping Liu, Feng Li, Chengshan Ma, Keli Ge
Article Number: 248
Published online on: 25 April 2023

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Article Open Access

Malignant adipocytic tumours: A 20‑year single‑centre retrospective study

Fernando Mendoza-Moreno, Belén Matías-García, Ana Quiroga-Valcárcel, Francisca García-Moreno Nisa, Cristina Díez-Corral, Alma Blázquez-Martín, Cristina Vera-Mansilla, Enrique Ovejero-Merino, Manuel Díez-Alonso, Lucía Diego-García, Melchor Alvarez-Mon, Miguel A. Ortega, Alberto Gutiérrez-Calvo
Article Number: 247
Published online on: 21 April 2023

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Article Open Access

SHCBP1 contributes to the proliferation and self‑renewal of cervical cancer cells and activation of the NF‑κB signaling pathway through EIF5A

Boya Deng, Ailin Li, Ying Zhu, Yingying Zhou, Jing Fei, Yuan Miao
Article Number: 246
Published online on: 21 April 2023

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Article Open Access

miR‑4732‑5p promotes ovarian cancer mobility by targeting MCUR1

Xin Li, Xiaoqin Wang, Jun Wu
Article Number: 245
Published online on: 20 April 2023

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Case Report

Multiple myeloma in a patient with chronic myeloid leukemia: A case report

Xiao-Lan Li, Min Li, Ling-Zhi Wang, Min Liang, Juan Tian, Zi-Wei Shi, Kui Song
Article Number: 244
Published online on: 20 April 2023

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Case Report Open Access

Well‑differentiated neuroendocrine tumor of the right kidney: A case report

Denghao Yang, Wen Tang, Tao Wu, Zeju Zhao, Guobiao Liang
Article Number: 243
Published online on: 20 April 2023

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Article Open Access

Knockdown of ASF1B inhibits cell proliferation, migration, invasion and cisplatin resistance in gastric cancer through the Myc pathway

Zao Zhang, Meiying Ning, Li Li, Zhuangzhuang Li, Yanrong Wang, Jing Zhao
Article Number: 242
Published online on: 20 April 2023

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Case Report Open Access

Lung carcinoma with small intestinal metastases and gastrointestinal bleeding: A rare case report

Tianzi Liu, Yan Geng, Zichuan Wang, Xintong Peng, Jing Liu, Yan Huang
Article Number: 241
Published online on: 20 April 2023

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Article Open Access

Clinicopathological and prognostic significance of SPARC expression in gastric cancer: A meta‑analysis and bioinformatics analysis

Jing Sun, Yang-Kai Bai, Zhi-Gang Fan
Article Number: 240
Published online on: 20 April 2023

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Retraction Open Access

[Retracted] Consecutive stimulation of HBsAg promotes the viability of the human B lymphoblastoid cell line IM‑9 through regulating the SIRT1‑NF‑κB pathway

Jian Bo, Xiaojuan Wang, Jie Li, Wenqing Wang, Jinqian Zhang
Article Number: 239
Published online on: 19 April 2023

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Article Open Access

AURKA, TOP2A and MELK are the key genes identified by WGCNA for the pathogenesis of lung adenocarcinoma

Yunqing Xu, Sen Wang, Bin Xu, Huiqing Lin, Na Zhan, Jiacai Ren, Wenling Song, Rong Han, Liping Cheng, Man Zhang, Xiuyun Zhang
Article Number: 238
Published online on: 19 April 2023

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Case Report Open Access

Diffuse large B‑cell lymphoma and monoclonal gammopathy secondary to immune thrombocytopenic purpura: A case report

Liwei Ren, Wenhui Liu, Tao Wu, Feng Xue, Dongfeng Mao, Lingling Yu, Hai Bai
Article Number: 237
Published online on: 19 April 2023

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Article Open Access

CD19/CD22 bispecific chimeric antigen receptor‑NK‑92 cells are developed and evaluated

Hyori Kim, Mina Han, Minsong Kim, Hyeri Kim, Ho Joon Im, Nayoung Kim, Kyung-Nam Koh
Article Number: 236
Published online on: 19 April 2023

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Correction Open Access

[Corrigendum] Expression of family with sequence similarity 172 member A and nucleotide‑binding protein 1 is associated with the poor prognosis of colorectal carcinoma

Wenjun Liu, Shuang Wang, Kai Qian, Jinqian Zhang, Zhi Zhang, Hao Liu
Article Number: 235
Published online on: 18 April 2023

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Case Report Open Access

Primary pulmonary intravascular large B‑cell lymphoma misdiagnosed as pneumonia: Four case reports and a literature review

Mengxia Zhu, Ying Chang, Haijian Fan, Jiong Shi, Bin Zhu, Xiaoli Mai
Article Number: 234
Published online on: 18 April 2023

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Case Report Open Access

Primary small cell thyroid carcinoma combined with poorly differentiated thyroid carcinoma, evidence for a common origin: A case report

Kyoung Min Kim, Ae Ri Ahn, Yong Tae Hong, Myoung Ja Chung
Article Number: 233
Published online on: 18 April 2023

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Article Open Access

Antitumor effects of NK cells expanded by activation pre‑processing of autologous feeder cells before irradiation in colorectal cancer

Eun-Kyoung Koh, Hong-Rae Lee, Woo-Chang Son, Ga-Young Park, Jaeho Bae, You-Soo Park
Article Number: 232
Published online on: 18 April 2023

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Article Open Access

Evaluation of sterol‑o‑acyl transferase 1 and cholesterol ester levels in plasma, peritoneal fluid and tumor tissue of patients with endometrial cancer: A pilot study

Vijayalakshmi N. Ayyagari, Miao Li, Paula Diaz-Sylvester, Kathleen Groesch, Teresa Wilson, Zvi Pasman, Ejaz M. Shah, Andrea Braundmeier-Fleming, Laurent Brard
Article Number: 231
Published online on: 18 April 2023

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Review

Molecular subtyping in colorectal cancer: A bridge to personalized therapy (Review)

Chunlin Wang, Hao Zhang, Yunxiao Liu, Yuliuming Wang, Hanqing Hu, Guiyu Wang
Article Number: 230
Published online on: 18 April 2023

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Case Report Open Access

Gallbladder neuroendocrine carcinoma: A report of two cases and literature review

Yong Liao, We Cao, Zhongkang Li, Xin Xu, Ye Zhang, Zhihu Liu, Jie Miao, Yang Zhou, Zhongguang Zhen, Dengxiang Liu, Hui Li, Lichao Chai, Yan Wei, Xiaochong Zhang, Le Zhang, Jitao Wang, Yanpeng Tian
Article Number: 229
Published online on: 13 April 2023

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Article Open Access

Endoscopic manifestations and treatment outcomes of asymptomatic gastric metastases from primary lung adenocarcinoma: Report of two cases

Meiling Wang, Wei Zhang, Chunmei Fu, Jian Guan, Xiaoguang Ni, Fang Yao
Article Number: 228
Published online on: 13 April 2023

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Case Report Open Access

Inflammatory myofibroblastic tumor of the urinary bladder with FN1‑ALK gene fusion: A case report

Seung-Myoung Son, Chang Gok Woo, Ok-Jun Lee, Yong June Kim, Ho-Chang Lee
Article Number: 227
Published online on: 13 April 2023

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Article Open Access

Buccinator muscle invasion is a risk factor for cervical lymph node metastasis in squamous cell carcinoma of the buccal mucosa: A retrospective study

Hideaki Hirai, Naoto Nishii, Yu Oikawa, Toshimitsu Ohsako, Takuma Kugimoto, Takeshi Kuroshima, Hirofumi Tomioka, Yasuyuki Michi, Kou Kayamori, Tohru Ikeda, Hiroyuki Harada
Article Number: 226
Published online on: 13 April 2023

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Article

Study on the mechanism of oral administration of tetrandrine during neoadjuvant chemotherapy for colon cancer

Dan Li, Junmei Li, Feng Yu, Bo Wang, Bing Liu
Article Number: 225
Published online on: 13 April 2023

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Article Open Access

Targeting transient receptor potential canonical 1 reduces non‑small cell lung cancer chemoresistance and stemness via inhibition of PI3K/AKT signaling

Jiahui Jin, Xinyu Yan, Yaru Zhao, Haojie Zhang, Kai Zhuang, Yating Wen, Jingjing He, Junzhen Gao
Article Number: 224
Published online on: 13 April 2023

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Article Open Access

Progesterone and its metabolite allopregnanolone promote invasion of human glioblastoma cells through metalloproteinase‑9 and cSrc kinase

Claudia Bello-Alvarez, Carmen J. Zamora-Sánchez, Karla M. Peña-Gutiérrez, Ignacio Camacho-Arroyo
Article Number: 223
Published online on: 13 April 2023

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Article Open Access

A validation study for the utility of serum microRNA as a diagnostic and prognostic marker in patients with osteosarcoma

Yoshihiro Araki, Naofumi Asano, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Takeshi Yoshida, Rikinari Hanayama, Juntaro Matsuzaki, Takahiro Ochiya, Akira Kawai, Hiroyuki Tsuchiya
Article Number: 222
Published online on: 13 April 2023

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Case Report Open Access

Synchronous ipsilateral papillary renal cell carcinoma and urothelial carcinoma: A case report

Muhamed Hussen Babarasul, Rawa Bapir, Dalshad Hama Khurshid Rahman, Saman Salih Fakhralddin, Fahmi H. Kakamad, Soran H. Tahir, Rawa M. Ali, Berun A. Abdalla, Shvan H. Mohammed, Dlsoz M. Hussein
Article Number: 221
Published online on: 13 April 2023

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Case Report Open Access

Primary signet‑ring cell melanoma of the anorectum: A case report

Hongyan Ma, Shuai Shi, Zhigang Zhang, Honggang Liu
Article Number: 220
Published online on: 13 April 2023

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Article Open Access

Resectability in bronchogenic carcinoma: A single‑center experience

Mohammed Mowafaq Marie, Sabah N. Jaber, Okba F. Ahmed, Fahmi H. Kakamad, Bnar J. Hama Amin, Soran H. Tahir, Abdulwahid M. Salih, Shalaw H. Abdalla, Razhan K. Ali, Rezheen J. Rashid, Shvan H. Mohammed, Shevan M. Mustafa, Rebwar A. Ali, Hawbash M. Rahim
Article Number: 219
Published online on: 12 April 2023

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Article Open Access

Anticancer effect of involucrasin A on colorectal cancer cells by modulating the Akt/MDM2/p53 pathway

Chengming Wei, Jingjing Du, Yunfu Shen, Zi Wang, Qianyu Lin, Junhe Chen, Fuming Zhang, Wanjun Lin, Zhibin Wang, Zhuya Yang, Wenzhe Ma
Article Number: 218
Published online on: 12 April 2023

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Review Special Issue

Functions of circular RNAs and their potential applications in gastric cancer (Review)

Kuanyu Xia, Zuzhen Wang, Bing Liu, Wenjun Wang, Yang Liu, Jianzhou Tang, Jinpeng Yan
Article Number: 217
Published online on: 12 April 2023

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Article Open Access

Germline multigene panel testing of patients with endometrial cancer

Jan Kral, Sandra Jelinkova, Petra Zemankova, Michal Vocka, Marianna Borecka, Leona Cerna, Marta Cerna, Lukas Dostalek, Petra Duskova, Lenka Foretova, Ondrej Havranek, Klara Horackova, Milena Hovhannisyan, Stepan Chvojka, Marta Kalousova, Marcela Kosarova, Monika Koudova, Vera Krutilkova, Eva Machackova, Petr Nehasil, Jan Novotny, Barbora Otahalova, Alena Puchmajerova, Marketa Safarikova, Jiri Slama, Viktor Stranecky, Ivan Subrt, Spiros Tavandzis, Michal Zikan, Tomas Zima, Jana Soukupova, Petra Kleiblova, Zdenek Kleibl, Marketa Janatova
Article Number: 216
Published online on: 12 April 2023

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HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis

Qinrong Wang, Xuanjing Gou, Lingling Liu, Ting Zhang, Hang Yuan, Yan Zhao, Yuan Xie, Jianjiang Zhou, Kewei Song
Article Number: 215
Published online on: 12 April 2023

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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