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Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas

  • Authors:
    • Lixiu Cao
    • Haoxuan Yang
    • Deshun Yao
    • Haifeng Cai
    • Huijing Wu
    • Yixing Yu
    • Lei Zhu
    • Wengui Xu
    • Yongliang Liu
    • Jingwu Li
  • View Affiliations / Copyright

    Affiliations: Department of Nuclear Medical Imaging, Tangshan People's Hospital, Tangshan, Hebei 063000, P.R. China, Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050010, P.R. China, Department of Oncology Surgery, Tangshan People's Hospital, Tangshan, Hebei 063000, P.R. China, Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China, Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300000, P.R. China, Department of Neurosurgery, Tangshan People's Hospital, Tangshan, Hebei 063000, P.R. China, Department of Tumor Surgery, Tangshan People's Hospital, Tangshan, Hebei 063000, P.R. China
    Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 340
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    Published online on: May 28, 2024
       https://doi.org/10.3892/ol.2024.14472
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Abstract

The aim of the present study was to develop and evaluate a clinical‑imaging‑radiomic nomogram based on pre‑enhanced computed tomography (CT) for pre‑operative differentiation lipid‑poor adenomas (LPAs) from metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas (AIs). A total of 196 consecutive patients with lung cancer, who underwent initial chest or abdominal pre‑enhanced CT scan with small hyperattenuating AIs, were included. The patients were randomly divided into a training cohort with 71 cases of LPAs and 66 cases of metastases, and a testing cohort with 31 cases of LPAs and 28 cases of metastases. Plain CT radiological and clinical features were evaluated, including sex, age, size, pre‑enhanced CT value (CTpre), shape, homogeneity and border. A total of 1,316 radiomic features were extracted from the plain CT images of the AIs, and the significant features selected by the least absolute shrinkage and selection operator were used to establish a Radscore. Subsequently, a clinical‑imaging‑radiomic model was developed by multivariable logistic regression incorporating the Radscore with significant clinical and imaging features. This model was then presented as a nomogram. The performance of the nomogram was assessed by calibration curves and decision curve analysis (DCA). A total of 4 significant radiomic features were incorporated in the Radscore, which yielded notable area under the receiver operating characteristic curves (AUCs) of 0.920 in the training dataset and 0.888 in the testing dataset. The clinical‑imaging‑radiomic nomogram incorporating the Radscore, CTpre, sex and age revealed favourable differential diagnostic performance (AUC: Training, 0.968; testing, 0.915) and favourable calibration curves. The nomogram was revealed to be more useful than the Radscore and the clinical‑imaging model in clinical practice by DCA. The clinical‑imaging‑radiomics nomogram based on initial plain CT images by integrating the Radscore and clinical‑imaging factors provided a potential tool to effectively differentiate LPAs from metastases in patients with lung cancer with small hyperattenuating AIs.
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1 

Barzon L, Sonino N, Fallo F, Palu G and Boscaro M: Prevalence and natural history of adrenal incidentalomas. Eur J Endocrinol. 149:273–285. 2003. View Article : Google Scholar : PubMed/NCBI

2 

Song JH, Chaudhry FS and Mayo-Smith WW: The incidental adrenal mass on CT: Prevalence of adrenal disease in 1,049 consecutive adrenal masses in patients with no known malignancy. AJR Am J Roentgenol. 190:1163–1168. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Fassnacht M, Arlt W, Bancos I, Dralle H, Newell-Price J, Sahdev A, Tabarin A, Terzolo M, Tsagarakis S and Dekkers OM: Management of adrenal incidentalomas: European society of endocrinology clinical practice guideline in collaboration with the european network for the study of adrenal tumors. Eur J Endocrinol. 175:G1–G34. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Andersen MB, Bodtger U, Andersen IR, Thorup KS, Ganeshan B and Rasmussen F: Metastases or benign adrenal lesions in patients with histopathological verification of lung cancer: Can CT texture analysis distinguish? Eur J Radiol. 138:1096642021. View Article : Google Scholar : PubMed/NCBI

5 

Terzolo M, Stigliano A, Chiodini I, Loli P, Furlani L, Arnaldi G, Reimondo G, Pia A, Toscano V, Zini M, et al: AME position statement on adrenal incidentaloma. Eur J Endocrinol. 164:851–870. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Gaujoux S and Mihai R; Joint working group of ESES and ENSAT, : European society of endocrine surgeons (ESES) and european network for the study of adrenal tumours (ENSAT) recommendations for the surgical management of adrenocortical carcinoma. Br J Surg. 104:358–376. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Young WF Jr: Clinical practice. The incidentally discovered adrenal mass. N Engl J Med. 356:601–610. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Ilias I, Sahdev A, Reznek RH, Grossman AB and Pacak K: The optimal imaging of adrenal tumours: A comparison of different methods. Endocr Relat Cancer. 14:587–599. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Zeiger MA, Siegelman SS and Hamrahian AH: Medical and surgical evaluation and treatment of adrenal incidentalomas. J Clin Endocrinol Metab. 96:2004–2015. 2011. View Article : Google Scholar : PubMed/NCBI

10 

Mayo-Smith WW, Song JH, Boland GL, Francis IR, Israel GM, Mazzaglia PJ, Berland LL and Pandharipande PV: Management of incidental adrenal masses: A white paper of the ACR incidental findings committee. J Am Coll Radiol. 14:1038–1044. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Bednarczuk T, Bolanowski M, Sworczak K, Górnicka B, Cieszanowski A, Otto M, Ambroziak U, Pachucki J, Kubicka E, Babińska A, et al: Adrenal incidentaloma in adults-management recommendations by the Polish society of endocrinology. Endokrynol Pol. 67:234–258. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Pandharipande PV, Herts BR, Gore RM, Mayo-Smith WW, Harvey HB, Megibow AJ and Berland LL: Rethinking normal: Benefits and risks of not reporting harmless incidental findings. J Am Coll Radiol. 13:764–767. 2016. View Article : Google Scholar : PubMed/NCBI

13 

Fujiyoshi F, Nakajo M, Fukukura Y and Tsuchimochi S: Characterization of adrenal tumors by chemical shift fast low-angle shot MR imaging: Comparison of four methods of quantitative evaluation. AJR Am J Roentgenol. 180:1649–1657. 2003. View Article : Google Scholar : PubMed/NCBI

14 

Guerin C, Pattou F, Brunaud L, Lifante JC, Mirallié E, Haissaguerre M, Huglo D, Olivier P, Houzard C, Ansquer C, et al: Performance of 18F-FDG PET/CT in the characterization of adrenal masses in noncancer patients: A prospective study. J Clin Endocrinol Metab. 102:2465–2472. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Caoili EM, Korobkin M, Francis IR, Cohan RH, Platt JF, Dunnick NR and Raghupathi KI: Adrenal masses: Characterization with combined unenhanced and delayed enhanced CT. Radiology. 222:629–633. 2002. View Article : Google Scholar : PubMed/NCBI

16 

Haider MA, Ghai S, Jhaveri K and Lockwood G: Chemical shift MR imaging of hyperattenuating (>10 HU) adrenal masses: does it still have a role? Radiology. 231:711–716. 2004. View Article : Google Scholar : PubMed/NCBI

17 

Koo HJ, Choi HJ, Kim HJ, Kim SO and Cho KS: The value of 15-minute delayed contrast-enhanced CT to differentiate hyperattenuating adrenal masses compared with chemical shift MR imaging. Eur Radiol. 24:1410–1420. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Akkus G, Guney IB, Ok F, Evran M, Izol V, Erdogan S, Bayazit Y, Sert M and Tetiker T: Diagnostic efficacy of 18F-FDG PET/CT in patients with adrenal incidentaloma. Endocr Connect. 8:838–845. 2019. View Article : Google Scholar : PubMed/NCBI

19 

Kassirer JP: Our stubborn quest for diagnostic certainty. A cause of excessive testing. N Engl J Med. 320:1489–1491. 1989. View Article : Google Scholar : PubMed/NCBI

20 

Lambin P, Leijenaar RTH, Deist TM, Peerlings J, de Jong EEC, van Timmeren J, Sanduleanu S, Larue R, Even AJG, Jochems A, et al: Radiomics: the bridge between medical imaging and personalized medicine. Nat Rev Clin Oncol. 14:749–762. 2017. View Article : Google Scholar : PubMed/NCBI

21 

Yang C, Jiang Z, Cheng T, Zhou R, Wang G, Jing D, Bo L, Huang P, Wang J, Zhang D, et al: Radiomics for predicting response of neoadjuvant chemotherapy in nasopharyngeal carcinoma: A systematic review and meta-analysis. Front Oncol. 12:8931032022. View Article : Google Scholar : PubMed/NCBI

22 

Gillies RJ, Kinahan PE and Hricak H: Radiomics: Images are more than pictures, they are data. Radiology. 278:563–577. 2016. View Article : Google Scholar : PubMed/NCBI

23 

Zhang Z, Yang J, Ho A, Jiang W, Logan J, Wang X, Brown PD, McGovern SL, Guha-Thakurta N, Ferguson SD, et al: Correction to: A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images. Eur Radiol. 28:3570–3571. 2018. View Article : Google Scholar : PubMed/NCBI

24 

Nishino M, Jagannathan JP, Ramaiya NH and Van den Abbeele AD: Revised RECIST guideline version 1.1: What oncologists want to know and what radiologists need to know. AJR Am J Roentgenol. 195:281–289. 2010. View Article : Google Scholar : PubMed/NCBI

25 

Lee HY, Oh YL and Park SY: Hyperattenuating adrenal lesions in lung cancer: Biphasic CT with unenhanced and 1-min enhanced images reliably predicts benign lesions. Eur Radiol. 31:5948–5958. 2021. View Article : Google Scholar : PubMed/NCBI

26 

Liu H, Guan X, Xu B, Zeng F, Chen C, Yin HL, Yi X, Peng Y and Chen BT: Computed tomography-based machine learning differentiates adrenal pheochromocytoma from lipid-poor adenoma. Front Endocrinol (Lausanne). 13:8334132022. View Article : Google Scholar : PubMed/NCBI

27 

Zhang GM, Shi B, Sun H, Jin ZY and Xue HD: Differentiating pheochromocytoma from lipid-poor adrenocortical adenoma by CT texture analysis: feasibility study. Abdom Radiol (NY). 42:2305–2313. 2017. View Article : Google Scholar : PubMed/NCBI

28 

Ettinghausen SE and Burt ME: Prospective evaluation of unilateral adrenal masses in patients with operable non-small-cell lung cancer. J Clin Oncol. 9:1462–1466. 1991. View Article : Google Scholar : PubMed/NCBI

29 

Yi X, Guan X, Zhang Y, Liu L, Long X, Yin H, Wang Z, Li X, Liao W, Chen BT and Zee C: Radiomics improves efficiency for differentiating subclinical pheochromocytoma from lipid-poor adenoma: A predictive, preventive and personalized medical approach in adrenal incidentalomas. EPMA J. 9:421–429. 2018. View Article : Google Scholar : PubMed/NCBI

30 

He K, Zhang ZT, Wang ZH, Wang Y, Wang YX, Zhang HZ, Dong YF and Xiao XL: A clinical-radiomic nomogram based on unenhanced computed tomography for predicting the risk of aldosterone-producing adenoma. Front Oncol. 11:6348792021. View Article : Google Scholar : PubMed/NCBI

31 

Ho LM, Samei E, Mazurowski MA, Zheng Y, Allen BC, Nelson RC and Marin D: Can texture analysis be used to distinguish benign from malignant adrenal nodules on unenhanced CT, contrast-enhanced CT, or in-phase and opposed-phase MRI? AJR Am J Roentgenol. 212:554–561. 2019. View Article : Google Scholar : PubMed/NCBI

32 

Tu W, Verma R, Krishna S, McInnes MDF, Flood TA and Schieda N: Can adrenal adenomas be differentiated from adrenal metastases at single-phase contrast-enhanced CT? AJR Am J Roentgenol. 211:1044–1050. 2018. View Article : Google Scholar : PubMed/NCBI

33 

de Groot P and Munden RF: Lung cancer epidemiology, risk factors, and prevention. Radiol Clin North Am. 50:863–876. 2012. View Article : Google Scholar : PubMed/NCBI

34 

Moawad AW, Ahmed A, Fuentes DT, Hazle JD, Habra MA and Elsayes KM: Machine learning-based texture analysis for differentiation of radiologically indeterminate small adrenal tumors on adrenal protocol CT scans. Abdom Radiol (NY). 46:4853–4863. 2021. View Article : Google Scholar : PubMed/NCBI

35 

You X, Sun X, Yang C and Fang Y: CT diagnosis and differentiation of benign and malignant varieties of solitary fibrous tumor of the pleura. Medicine (Baltimore). 96:e90582017. View Article : Google Scholar : PubMed/NCBI

36 

Ganeshan B, Goh V, Mandeville HC, Ng QS, Hoskin PJ and Miles KA: Non-small cell lung cancer: Histopathologic correlates for texture parameters at CT. Radiology. 266:326–336. 2013. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Cao L, Yang H, Yao D, Cai H, Wu H, Yu Y, Zhu L, Xu W, Liu Y, Li J, Li J, et al: Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas. Oncol Lett 28: 340, 2024.
APA
Cao, L., Yang, H., Yao, D., Cai, H., Wu, H., Yu, Y. ... Li, J. (2024). Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas. Oncology Letters, 28, 340. https://doi.org/10.3892/ol.2024.14472
MLA
Cao, L., Yang, H., Yao, D., Cai, H., Wu, H., Yu, Y., Zhu, L., Xu, W., Liu, Y., Li, J."Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas". Oncology Letters 28.2 (2024): 340.
Chicago
Cao, L., Yang, H., Yao, D., Cai, H., Wu, H., Yu, Y., Zhu, L., Xu, W., Liu, Y., Li, J."Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas". Oncology Letters 28, no. 2 (2024): 340. https://doi.org/10.3892/ol.2024.14472
Copy and paste a formatted citation
x
Spandidos Publications style
Cao L, Yang H, Yao D, Cai H, Wu H, Yu Y, Zhu L, Xu W, Liu Y, Li J, Li J, et al: Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas. Oncol Lett 28: 340, 2024.
APA
Cao, L., Yang, H., Yao, D., Cai, H., Wu, H., Yu, Y. ... Li, J. (2024). Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas. Oncology Letters, 28, 340. https://doi.org/10.3892/ol.2024.14472
MLA
Cao, L., Yang, H., Yao, D., Cai, H., Wu, H., Yu, Y., Zhu, L., Xu, W., Liu, Y., Li, J."Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas". Oncology Letters 28.2 (2024): 340.
Chicago
Cao, L., Yang, H., Yao, D., Cai, H., Wu, H., Yu, Y., Zhu, L., Xu, W., Liu, Y., Li, J."Clinical‑imaging‑radiomic nomogram based on unenhanced CT effectively predicts adrenal metastases in patients with lung cancer with small hyperattenuating adrenal incidentalomas". Oncology Letters 28, no. 2 (2024): 340. https://doi.org/10.3892/ol.2024.14472
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