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Case Report Open Access

Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review

  • Authors:
    • Wen Wei
    • Chunyu Gong
    • Renjie Wei
    • Xu Luo
    • Yuhao Liu
    • Guo Chen
    • Ruitu Ran
    • Fudong Liu
  • View Affiliations / Copyright

    Affiliations: Department of Urology, West China Tianfu Hospital of Sichuan University, Sichuan University, Chengdu, Sichuan 610000, P.R. China, Department of Urology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610000, P.R. China
    Copyright: © Wei et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 557
    |
    Published online on: September 19, 2024
       https://doi.org/10.3892/ol.2024.14690
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Abstract

The present study describes the case of a 71‑year‑old male patient that presented with generalized lymphadenopathy and a pelvic mass, but no signs of bone and visceral metastasis. Their total prostate‑specific antigen level was >100 ng/ml. A biopsy of the pelvic mass, situated near the left iliac vessels, confirmed the existence of an adenocarcinoma originating from the prostate and a subsequent prostate biopsy indicated a Gleason score of 4+5. Endocrine treatment with bicalutamide and goserelin (androgen deprivation therapy) resulted in only a partial response of the left iliac metastatic lesions to the treatment. The subsequent treatment plan of androgen deprivation therapy and abiraterone plus docetaxel did not change the progression of the disease. The patient finally developed inferior vena cava syndrome. Subsequently, the patient declined both a re‑biopsy of the prostate and enlarged cervical lymph nodes, and interventions by a vascular surgeon. To the best of our knowledge, the present study is the first documented case of a natural progression of metastatic prostate cancer with inferior vena cava syndrome.
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Copy and paste a formatted citation
Spandidos Publications style
Wei W, Gong C, Wei R, Luo X, Liu Y, Chen G, Ran R and Liu F: Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review. Oncol Lett 28: 557, 2024.
APA
Wei, W., Gong, C., Wei, R., Luo, X., Liu, Y., Chen, G. ... Liu, F. (2024). Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review. Oncology Letters, 28, 557. https://doi.org/10.3892/ol.2024.14690
MLA
Wei, W., Gong, C., Wei, R., Luo, X., Liu, Y., Chen, G., Ran, R., Liu, F."Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review". Oncology Letters 28.6 (2024): 557.
Chicago
Wei, W., Gong, C., Wei, R., Luo, X., Liu, Y., Chen, G., Ran, R., Liu, F."Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review". Oncology Letters 28, no. 6 (2024): 557. https://doi.org/10.3892/ol.2024.14690
Copy and paste a formatted citation
x
Spandidos Publications style
Wei W, Gong C, Wei R, Luo X, Liu Y, Chen G, Ran R and Liu F: Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review. Oncol Lett 28: 557, 2024.
APA
Wei, W., Gong, C., Wei, R., Luo, X., Liu, Y., Chen, G. ... Liu, F. (2024). Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review. Oncology Letters, 28, 557. https://doi.org/10.3892/ol.2024.14690
MLA
Wei, W., Gong, C., Wei, R., Luo, X., Liu, Y., Chen, G., Ran, R., Liu, F."Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review". Oncology Letters 28.6 (2024): 557.
Chicago
Wei, W., Gong, C., Wei, R., Luo, X., Liu, Y., Chen, G., Ran, R., Liu, F."Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review". Oncology Letters 28, no. 6 (2024): 557. https://doi.org/10.3892/ol.2024.14690
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