Misdiagnosis of esophageal leiomyoma combined with adrenal cortical adenoma as esophageal cancer with adrenal metastasis by fluorine-18-fluorodeoxyglucose positron emission tomography: A case report

Sun,Xiaoming; Lv,Lin; Fan,Daming; Huang,Yubin; Zhu,Liangming; Liu,Haibo

doi:10.3892/ol.2025.14984

May-2025 Volume 29 Issue 5

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Misdiagnosis of esophageal leiomyoma combined with adrenal cortical adenoma as esophageal cancer with adrenal metastasis by fluorine-18-fluorodeoxyglucose positron emission tomography: A case report

Authors:
- Xiaoming Sun
- Lin Lv
- Daming Fan
- Yubin Huang
- Liangming Zhu
- Haibo Liu
View Affiliations / Copyright

Affiliations: Department of Thoracic Surgery, Jinan Central Hospital, Jinan, Shandong 250013, P.R. China, Department of Pathology, Jinan Central Hospital, Jinan, Shandong 250013, P.R. China

Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 238
|
Published online on: March 20, 2025

https://doi.org/10.3892/ol.2025.14984
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Abstract

Leiomyoma is a benign muscular abnormality that commonly occurs in the middle and distal third of the esophagus, leading to thickening of the esophageal wall and subsequent esophageal luminal narrowing. Notably, esophageal leiomyoma often does not show increased 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET). The present study described a case of esophageal leiomyoma combined with adrenal adenoma. Results of the PET-computed tomography analysis revealed that FDG metabolism was increased in the lower segment of the esophagus and the left adrenal gland, with maximum standardized uptake values of 6.5 and 4.1, respectively. Therefore, initially, the patient was diagnosed with an esophageal malignant tumor with left adrenal metastasis. Open surgery was performed for complete removal of the lesions, and results of a routine pathological analysis revealed esophageal leiomyoma combined with adrenal cortical adenoma. The present study indicates that to avoid unnecessary surgeries, esophageal leiomyoma and adrenal cortical adenoma should be diagnosed through a comprehensive assessment with endoscopy, endoscopic ultrasound, computed tomography, magnetic resonance imaging and tissue sample pathology, not just PET.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Misdiagnosis of esophageal leiomyoma combined with adrenal cortical adenoma as esophageal cancer with adrenal metastasis by fluorine-18-fluorodeoxyglucose positron emission tomography: A case report

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