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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2025 Volume 29 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report

Primary leiomyosarcoma of the ureter: A case report

Raffaele Baio, Olivier Intilla, Giovanni Molisso, Umberto Di Mauro, Diodato Ferrante, Giuseppe Di Lorenzo, Carlo Buonerba, Rita Citarella, Tommaso Pagano, Roberto Sanseverino
Article Number: 258
Published online on: 01 April 2025

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Robot‑assisted laparoscopic partial cystectomy for urachal carcinoma: A case report

Chujin Ye, Qifan Xie, Zhiye Liu, Fangqianyu Zhong, Kun Wei, Xiaoyong Pu
Article Number: 257
Published online on: 01 April 2025

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Case Report Open Access

Gastric carcinoma harbouring loss‑of‑function mutations in the PIK3R1, ATRX and RBM10 genes exhibits diverse histological features associated with EBV infection and TP53 inactivation: A case report

Se Un Jeong, Euno Choi, Yongil Kim, Jaeyoung Byeon, So-Woon Kim
Article Number: 256
Published online on: 01 April 2025

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Article Open Access

Bone mesenchymal stem cell‑derived exosome‑encapsulated microRNA‑125b‑5p inhibits ovarian cancer progression via DDX5 downregulation

Yuxia Wang, Wei Wang, Dan Zheng, Ying Gao
Article Number: 255
Published online on: 01 April 2025

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Correction Open Access

[Corrigendum] Knockdown of lncRNA C5orf66‑AS1 inhibits osteosarcoma cell proliferation and invasion via miR‑149‑5p upregulation

Hui Zhang, Jie Song
Article Number: 254
Published online on: 31 March 2025

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Case Report Open Access

Achieving stringent complete remission in relapsed/refractory multiple myeloma with liver extramedullary disease after CAR‑T cell therapy: A case report

Lingyun Zhou, Danbo Liu, Fang Du, Jiao Chen, Wenyi Lu, Hongxian Xiang, Haifei Chen
Article Number: 253
Published online on: 28 March 2025

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Article Open Access

Predicting prognosis of patients with triple‑negative breast cancer undergoing neoadjuvant chemotherapy based on inflammatory status at different time points: A propensity score matching analysis

Qian Guo, Bingping Wang, Xinran Gao, Pu Zhao, Shuang Lv
Article Number: 252
Published online on: 27 March 2025

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Article Open Access

Respiratory microbiota diversity as a predictive biomarker for the efficacy of PD‑1 blockades in patients with advanced non‑small cell lung cancer: A retrospective exploratory study

Liang Zhang, Ming-Jiang Li, Xiao-Ping Li, Bo Yang, Ting Xiao, Ping Wang, Wei-Dong Zhang
Article Number: 251
Published online on: 26 March 2025

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Article Open Access

Role of ELP6 in tumour progression and impact on ERK1/2 signalling pathway inhibitors in skin cutaneous melanoma

Ying Liu, Qinrong Wang, Qian Li, Peng Ren
Article Number: 250
Published online on: 26 March 2025

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Article Open Access

Risk score model for predicting local control and survival in patients with rectal cancer treated with neoadjuvant chemoradiotherapy

Tuba Kurt Catal, Günay Can, İsmai̇l Fati̇h Demi̇rel, Sefi̇ka Arzu Ergen, Di̇dem Colpan Öksüz
Article Number: 249
Published online on: 26 March 2025

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Case Report Open Access

Tongue squamous cell carcinoma masked by herpes simplex virus infection: A case report

Hideaki Sato, Masanori Takekawa, Sayaka Yuzawa, Masayuki Motohashi, Shinya Matsuda, Makoto Adachi
Article Number: 248
Published online on: 26 March 2025

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Case Report Open Access

TP53 gene mutation in lymphoepithelioma‑like carcinoma of the breast with thyroid cancer: A case report

Jie Sun, Jiyue Gao, Jun Li, Haidong Zhao
Article Number: 247
Published online on: 26 March 2025

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Article Open Access

Machine learning‑based construction of damage‑associated molecular patterns related score identifies subtypes of pancreatic adenocarcinoma with distinct prognosis

Jing Liang, Hui Wu, Zewen Song, Guoyin Li, Jianfeng Zhang, Wenxin Ding
Article Number: 246
Published online on: 24 March 2025

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Article Open Access

The feasible role of soluble E‑cadherin in spheroidogenesis of HCT116 colorectal cancer cells, a candidate biomarker for liquid biopsy

In-Youb Chang, Hye-Jin Boo, Jin Won Hyun, Sang-Pil Yoon
Article Number: 245
Published online on: 24 March 2025

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Article Open Access

Recombinant human‑endostatin combined with sintilimab and chemotherapy in first‑line treatment of locally advanced or metastatic esophageal squamous cell carcinoma

Shiyun Cui, Lei Fan, Xinnan Sun, Yucheng Cai, Ting Wang, Ping Li, Rong Wang, Lianke Liu
Article Number: 244
Published online on: 24 March 2025

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Review Open Access

Key genes altered in glioblastoma based on bioinformatics (Review)

Marcelino Al Ghafari, Nour El Jaafari, Mariam Mouallem, Tala Maassarani, Mirvat El-Sibai, Ralph Abi-Habib
Article Number: 243
Published online on: 24 March 2025

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Article Open Access

SNP array analysis facilitates the identification of novel chromosomal alterations associated with disease and SNPs related to adverse drug reactions in neuroblastoma

Kailan Chen, Hanpeng Li, Yujie Luo, Jiaqi Liu, Huichao Liu, Yongli Tian, Yifei Yu, Yun Xu, Li Chen, Qiong Xu, Ying Li
Article Number: 242
Published online on: 24 March 2025

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Article Open Access

Treatment outcomes and safety of reduced‑dose venetoclax plus antifungal agents to treat acute myeloid leukemia: A single hospital experience in Taiwan

Sheng-Yen Hsiao, Kun-Yu Wu, Wen-Tsung Huang, Cheng-Yao Lin, Kuan-Yu Chen, Teng-Song Weng
Article Number: 241
Published online on: 21 March 2025

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Review Open Access

Research progress of sintilimab in the treatment of cancer (Review)

Yuan-Yuan Wu, Hua Shao
Article Number: 240
Published online on: 21 March 2025

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Article Open Access

Impact of sirtuin‑1 expression on progression‑free survival in non‑endometrioid endometrial cancer: A retrospective cohort study

Necim Yalcin, Hulya Tosun Yildirim, Aysun Alci, Mustafa Gokkaya, Mehmet Goksu, Isin Ureyen, Tayfun Toptas
Article Number: 239
Published online on: 20 March 2025

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Case Report Open Access

Misdiagnosis of esophageal leiomyoma combined with adrenal cortical adenoma as esophageal cancer with adrenal metastasis by fluorine-18-fluorodeoxyglucose positron emission tomography: A case report

Xiaoming Sun, Lin Lv, Daming Fan, Yubin Huang, Liangming Zhu, Haibo Liu
Article Number: 238
Published online on: 20 March 2025

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Article Open Access

Development and application of an early warning model for predicting early mortality following stent placement in malignant biliary obstruction: A comparative analysis of logistic regression and artificial neural network approaches

Yongxin Ma, Jiaojiao Qi, Xusheng Zhang, Kejun Liu, Yimin Liu, Xuehai Yu, Yang Bu, Bendong Chen
Article Number: 237
Published online on: 20 March 2025

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Article Open Access

Effects of SB939 are mediated by STAT3 to inhibit breast cancer cell metastasis‑related genes

Chen-Hui Qin, Shu-Min Zhang, Xiao-Ou Huo, Ruo-Piao Song, Jun Ling
Article Number: 236
Published online on: 19 March 2025

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Article Open Access

Predictive and therapeutic value of the ferroptosis gene CISD1 in non‑small cell lung cancer

Tao Wang, Xiaoyu Xiao, Zhe Zhang, Xiang Li
Article Number: 235
Published online on: 18 March 2025

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Case Report Open Access

Personalized combination therapy for diffuse midline glioma: A case report

Mengqi Sun, Jizhou Zheng, Long Gong, Zihuang Li, Lijun Wang
Article Number: 234
Published online on: 17 March 2025

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Article Open Access

Comparative survival outcome of synchronous and metachronous brain metastasis from colorectal cancer: A meta‑analysis

Tsung-Chiao Tsai, Junmin Song, Kuan-Yu Chi, Hong-Min Lin, Yu Chang
Article Number: 233
Published online on: 17 March 2025

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Correction Open Access

[Corrigendum] Investigating the efficacy of tissue factor pathway inhibitor‑2 as a promising prognostic marker for ovarian cancer

Tomoka Maehana, Ryuji Kawaguchi, Kyohei Nishikawa, Naoki Kawahara, Yuki Yamada, Fuminori Kimura
Article Number: 232
Published online on: 17 March 2025

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Article Open Access

Prognostic value of the neutrophil‑to‑lymphocyte ratio in renal cell carcinoma: A systematic review and meta‑analysis

Kecheng Lou, Xin Cheng
Article Number: 231
Published online on: 13 March 2025

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Article Open Access

Identification of a novel FOXO3‑associated prognostic model in hepatocellular carcinoma

Songmei Guan, Qiang Lin, Peiwu Huang, Kangqiang Lin, Shigang Duan
Article Number: 230
Published online on: 13 March 2025

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Correction Open Access

[Corrigendum] RNA interference-mediated depletion of TRPM8 enhances the efficacy of epirubicin chemotherapy in prostate cancer LNCaP and PC3 cells

Tao Liu, Yixiang Liao, Huangheng Tao, Jinmin Zeng, Gang Wang, Zhonghua Yang, Yongzhi Wang, Yu Xiao, Jiajie Zhou, Xinghuan Wang
Article Number: 229
Published online on: 12 March 2025

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Article Open Access

Safety and efficacy outcomes of delta‑like ligand 3 inhibitors for the treatment of solid tumors: A systematic review and single‑arm meta‑analysis

Yaxu Su, Xinyu Lu, Tongwei Liu, Hengchang Chen, Wentong Xu, Yulu Qin, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 228
Published online on: 10 March 2025

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Case Report Open Access

Long‑term progression‑free survival in HR+/HER2+ advanced breast cancer with combination therapy with a CDK4/6 inhibitor and first‑line maintenance therapy: A case report

Yihong Cai, Jinling Zhang, Hongxia Duan, Fan Liu
Article Number: 227
Published online on: 10 March 2025

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Retraction Open Access

[Retracted] Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression

Liang Li, Ying Xu, Binquan Wang
Article Number: 226
Published online on: 10 March 2025

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Case Report Open Access

Adrenal cortical carcinoma with non‑islet cell tumor hypoglycemia: A case report

Yunpeng Li, Rui Yang, Liang Zhang, Jian Wang, Faying Yang, Song Tu, Jun Qian, Jiaxi Yao
Article Number: 225
Published online on: 07 March 2025

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Case Report Open Access

Coexistence of acute myeloid leukemia with a complex chromosomal translocation and monoclonal gammopathy of undetermined significance: A case report and literature review

Xue Qiao, Li Geng, Tian Tian, Jingnan Zhang, Xiaonan Guo, Shukai Qiao
Article Number: 224
Published online on: 07 March 2025

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Article Open Access

Methods for diagnosing malnutrition in patients with esophageal cancer, and the association with nutritional and inflammatory indices: A cross‑sectional study

Xueyuan Kong, Ping Liu, Guotian Wang, Shiqing Sun, Ling Li
Article Number: 223
Published online on: 05 March 2025

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Case Report Open Access

Synchronous occurrence of primary gastric and liver cancer: A case report

Xiaomin Zhang, Xiaoying Han
Article Number: 222
Published online on: 06 March 2025

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Article Special Issue Open Access

Cancer metastasis to the bone: Mechanisms and animal models (Review)

Meimei Deng, Hao Ding, Yuru Zhou, Guangying Qi, Jinfeng Gan
Article Number: 221
Published online on: 06 March 2025

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Article Open Access

Picropodophyllin, an IGF‑1 receptor inhibitor, enhances oxaliplatin efficacy in chemoresistant colorectal cancer HCT116 cells by reducing metastatic potential

Nurcin Kayacik, Hasan Kurter, Tolga Sever, Yasemin Basbinar, Gizem Calibasi‑Kocal
Article Number: 220
Published online on: 06 March 2025

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Correction Open Access

[Corrigendum] miR‑181a‑5p inhibits the proliferation and invasion of drug‑resistant glioblastoma cells by targeting F‑box protein 11 expression

Xueyan Wen, Songrong Li, Mengchan Guo, Hongzhan Liao, Yongmin Chen, Xi Kuang, Xiaoping Liao, Lin Ma, Qifu Li
Article Number: 219
Published online on: 05 March 2025

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Case Report Open Access

Castleman disease coexisting with papillary thyroid carcinoma: A case report

Fei Wu, Honghao Li, Rui Hai, Kefan Chen, Jie Yao, Yun Liu, Shanshan Liu, Xiangyu Zhou
Article Number: 218
Published online on: 05 March 2025

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Article Open Access

Prognostic value of HER2 expression in cervical adenocarcinoma:  A retrospective cohort study

Qing Xu, Zhuomin Yin, Yueqi Li, Xiu Zhu, Hanmei Lou, Juan Ni
Article Number: 217
Published online on: 05 March 2025

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Article Open Access

Expanding paclitaxel's therapeutic window: Investigating the pharmacokinetic, clinical formulation and mechanistic aspects of paclitaxel‑lipoate conjugate

Saleh Abu‑Lafi, Mizied Falah, Mouhammad Zeidan, Mahmoud Rayan, Anwar Rayan
Article Number: 216
Published online on: 05 March 2025

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Review Special Issue Open Access

Novel clinical potential of poly (ADP‑ribose) polymerase inhibitors in triple‑negative breast cancer: Mechanistic insights and clinical applications (Review)

Yu Han, Lei Wei
Article Number: 215
Published online on: 04 March 2025

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Article Open Access

Characteristics of patients with melanoma with non‑melanoma skin cancer comorbidity: Practical implications based on a retrospective study

Monika Słowińska, Iwona Czarnecka, Robert Czarnecki, Paulina Tatara, Anna Nasierowska‑Guttmejer, Małgorzata Lorent, Joanna Kania, Witold Owczarek
Article Number: 214
Published online on: 04 March 2025

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Review Open Access

ALDH1A1 in breast cancer: A prospective target to overcome therapy resistance (Review)

Lokman Varisli, Panagiotis Zoumpourlis, Demetrios A. Spandidos, Vassilis Zoumpourlis, Spiros Vlahopoulos
Article Number: 213
Published online on: 04 March 2025

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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