Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report 

  • Authors:
    • Binh Van Pham
    • Duy Duc Nguyen
    • Manh Dai Tran
    • Thanh Duy Nguyen
    • An Duc Thai
    • Binh Tien Nguyen
    • Ky Van Le
    • Hoa Thi Thanh Nguyen
  • View Affiliations

  • Published online on: May 8, 2025     https://doi.org/10.3892/ol.2025.15079
  • Article Number: 333
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Abstract

Primary gastric squamous cell carcinoma (PGSCC) is a rare form of gastric malignancy. The etiology remains unclear and no standardized treatment protocol or consensus has been established. The current study presents a rare case of PGSCC treated by total gastrectomy and extended D2 lymphadenectomy, alongside a review of related clinical literature. A 57‑year‑old man was diagnosed with primary SCC located at the lesser curvature of the gastric body. The patient underwent a total gastrectomy and extended D2 lymphadenectomy. Postoperative pathology confirmed a moderately differentiated SCC with perineural invasion, classified as stage T4bN2M0. Treatment strategies for PGSCC remain controversial, underscoring the need for further studies with larger sample sizes to clarify therapeutic approaches.
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July-2025
Volume 30 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Pham BV, Nguyen DD, Tran MD, Nguyen TD, Thai AD, Nguyen BT, Le KV and Nguyen HT: Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report . Oncol Lett 30: 333, 2025.
APA
Pham, B.V., Nguyen, D.D., Tran, M.D., Nguyen, T.D., Thai, A.D., Nguyen, B.T. ... Nguyen, H.T. (2025). Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report . Oncology Letters, 30, 333. https://doi.org/10.3892/ol.2025.15079
MLA
Pham, B. V., Nguyen, D. D., Tran, M. D., Nguyen, T. D., Thai, A. D., Nguyen, B. T., Le, K. V., Nguyen, H. T."Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report ". Oncology Letters 30.1 (2025): 333.
Chicago
Pham, B. V., Nguyen, D. D., Tran, M. D., Nguyen, T. D., Thai, A. D., Nguyen, B. T., Le, K. V., Nguyen, H. T."Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report ". Oncology Letters 30, no. 1 (2025): 333. https://doi.org/10.3892/ol.2025.15079