Recurrent malignant Triton tumour: First report on a long time survivor

  • Authors:
    • Wolfgang J. Köstler
    • Gabriele Amann
    • Thomas W. Grunt
    • Christian F. Singer
    • Sonja M. Schneider
    • Thomas Brodowicz
    • Sandra Tomek
    • Christoph C. Zielinski
  • View Affiliations

  • Published online on: May 1, 2003     https://doi.org/10.3892/or.10.3.533
  • Pages: 533-535
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Abstract

Malignant Triton tumour represents an extremely rare mesenchymal malignancy exhibiting histopathologic patterns of peripheral nerve sheath tumours and rhabdomyoblastic components, the latter usually determining the mostly fatal outcome. We report on a 26-year old patient diagnosed with malignant Triton tumour who developed multiple recurrences despite repeated aggressive surgery, chemo- and radiotherapy during an 8-year period. After Northern blotting analysis of an excised in-transit metastasis had revealed expression of retinoic receptors α and γ, the patient received experimental treatment with isotretinoin and interferon-α for one year and remains without any evidence of disease for more than three years. This is the first report on a long-term survivor of multiple recurrences of malignant Triton tumour.

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May-June 2003
Volume 10 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Köstler WJ, Amann G, Grunt TW, Singer CF, Schneider SM, Brodowicz T, Tomek S and Zielinski CC: Recurrent malignant Triton tumour: First report on a long time survivor. Oncol Rep 10: 533-535, 2003.
APA
Köstler, W.J., Amann, G., Grunt, T.W., Singer, C.F., Schneider, S.M., Brodowicz, T. ... Zielinski, C.C. (2003). Recurrent malignant Triton tumour: First report on a long time survivor. Oncology Reports, 10, 533-535. https://doi.org/10.3892/or.10.3.533
MLA
Köstler, W. J., Amann, G., Grunt, T. W., Singer, C. F., Schneider, S. M., Brodowicz, T., Tomek, S., Zielinski, C. C."Recurrent malignant Triton tumour: First report on a long time survivor". Oncology Reports 10.3 (2003): 533-535.
Chicago
Köstler, W. J., Amann, G., Grunt, T. W., Singer, C. F., Schneider, S. M., Brodowicz, T., Tomek, S., Zielinski, C. C."Recurrent malignant Triton tumour: First report on a long time survivor". Oncology Reports 10, no. 3 (2003): 533-535. https://doi.org/10.3892/or.10.3.533