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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2003 Volume 10 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Mucinous cystic tumor of the pancreas: Immunohistochemical assessment of ‘ovarian-type stroma’

Akihiko Izumo, Koji Yamaguchi, Takashi Eguchi, Kenichi Nishiyama, Hidetaka Yamamoto, Hirotoshi Yonemasu, Takashi Yao, Masao Tanaka, Masazumi Tsuneyoshi
Pages: 515-525
Published online on: 01 May 2003

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Article

Effect of p27Kip1 on the ability of invasion and metastasis of an oral cancer cell line

Supriatno, Koji Harada, Shinichi Kawaguchi, Hideo Yoshida, Mitsunobu Sato
Pages: 527-532
Published online on: 01 May 2003

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Article

Recurrent malignant Triton tumour: First report on a long time survivor

Wolfgang J. Köstler, Gabriele Amann, Thomas W. Grunt, Christian F. Singer, Sonja M. Schneider, Thomas Brodowicz, Sandra Tomek, Christoph C. Zielinski
Pages: 533-535
Published online on: 01 May 2003

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Article

Silk protein, sericin, suppresses DMBA-TPA-induced mouse skin tumorigenesis by reducing oxidative stress, inflammatory responses and endogenous tumor promoter TNF-α

Siqin Zhaorigetu, Noriyuki Yanaka, Masahiro Sasaki, Hiromitsu Watanabe, Norihisa Kato
Pages: 537-543
Published online on: 01 May 2003

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Article

DNA demethylation is directly related to tumour progression: Evidence in normal, pre-malignant and malignant cells from uterine cervix samples

Adriana De Capoa, Angelina Musolino, Simonetta Della Rosa, Paola Caiafa, Luciano Mariani, Franca Del Nonno, Amina Vocaturo, Raffaele Perrone Donnorso, Alain Niveleau, Claudio Grappelli
Pages: 545-549
Published online on: 01 May 2003

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Article

INI-1, a partner gene of ALL-1, is highly conserved in human acute leukemia

Koshi Mimori, Hiroshi Inoue, Hideshi Ishii, Masaki Mori
Pages: 551-553
Published online on: 01 May 2003

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Article

Alterations of p14ARF and p16INK4a genes in salivary gland carcinomas

Masayoshi Nishimine, Mitsutoshi Nakamura, Munehiro Kishi, Masumi Okamoto, Keiji Shimada, Eiwa Ishida, Tadaaki Kirita, Noboru Konishi
Pages: 555-560
Published online on: 01 May 2003

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Article

Clinical impact of thymidine phosphorylase expression in gastric cancer

Tsuyoshi Noguchi, Shozo Fujiwara, Shinsuke Takeno, Shinya Kai, Akari Mizuta, Yuko Nagao, Yuzo Uchida
Pages: 561-566
Published online on: 01 May 2003

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Article

Expression of matrix metalloproteinases 7 and 2 in human renal cell carcinoma

Toshiyuki Sumi, Tatsuya Nakatani, Hiroyuki Yoshida, Yooji Hyun, Tomoyo Yasui, Yoshinari Matsumoto, Eri Nakagawa, Kazunobu Sugimura, Hidenori Kawashima, Osamu Ishiko
Pages: 567-570
Published online on: 01 May 2003

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Article

BCL2 expression predicts survival in patients receiving synchronous chemoradiotherapy in advanced transitional cell carcinoma of the bladder

S. A. Hussain, R. Ganesan, L. Hiller, P. W. Cooke, P. Murray, L. S. Young, N. D. James
Pages: 571-576
Published online on: 01 May 2003

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Article

Management of Merkel cell carcinoma: Case series of 36 patients

Anja Müller, Ronald Keus, Norbert Neumann, Guido Lammering, Thomas Schnabel
Pages: 577-585
Published online on: 01 May 2003

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Article

Chromosomal aberrations of multiple myeloma in Chinese patients at diagnosis: A study by combined G-banding and multicolor spectral karyotyping

Margaret Heung-Ling Ng, Nathalie Wong, Tai Tap Lau, Kam Sze Tsang, Suk Hang Cheng, Natalie Pui-Ha Chan, Sheung Hang Tang, Kenny Ieng-Kit Lei, Yonna Leung
Pages: 587-591
Published online on: 01 May 2003

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Article

Antitumor activity of new combination chemotherapy with irinotecan hydrochloride and nedaplatin against human cervical cancer cell lines

Kaichiro Yamamoto, Michio Iwahana, Eiji Kumazawa, Koji Kakihata, Kunio Abe, Fuyumi Hirano, Akiko Tohgo, Hiroshi Hoshiai, Kiichiro Noda
Pages: 593-598
Published online on: 01 May 2003

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Article

The role of MTA1 gene expression in human hepatocellular carcinoma

Takayuki Hamatsu, Tatsuya Rikimaru, Yo-Ichi Yamashita, Shinichi Aishima, Shinji Tanaka, Ken Shirabe, Mitsuo Shimada, Yasushi Toh, Keizo Sugimachi
Pages: 599-604
Published online on: 01 May 2003

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Article

Technetium-99m tetrofosmin scintigraphy in pediatric osteogenic sarcoma

Orazio Schillaci, Angela Spanu, Francesco Scopinaro, Francesco Monteleone, Salvatore Masala, Umberto Tarantino, Giuseppe Madeddu, Giovanni Simonetti
Pages: 605-608
Published online on: 01 May 2003

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Article

Expression and regulation patterns of hyaluronidases in small cell lung cancer and glioma lines

Nanna Junker, Scilla Latini, Lone N. Petersen, Paul E.G. Kristjansen
Pages: 609-616
Published online on: 01 May 2003

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Article

Anti-angiogenic activity of conjugated linoleic acid on basic fibroblast growth factor-induced angiogenesis

Eun-Joung Moon, You Mie Lee, Kyu-Won Kim
Pages: 617-621
Published online on: 01 May 2003

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Article

Detection of disseminated cancer cells in rib marrow of patients with esophageal cancer

Tsuyoshi Noguchi, Tomotaka Shibata, Shoichi Fumoto, Tetsuro Sato, Yuzo Uchida, Tsutomu Daa, Shigeo Yokoyama, Helmut E. Gabbert, Wolfram Mueller, Shinsuke Takeno
Pages: 623-627
Published online on: 01 May 2003

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Article

Ionizing radiation and nitric oxide donor sensitize Fas-induced apoptosis via up-regulation of Fas in human cervical cancer cells

In-Chul Park, Sang-Hyeok Woo, Myung-Jin Park, Hyung-Chahn Lee, Su-Jae Lee, Young-Joon Hong, Seung-Hoon Lee, Seok-Il Hong, Chang-Hun Rhee
Pages: 629-633
Published online on: 01 May 2003

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Article

Urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 and type 2 in stage I malignant melanoma

Borut Stabuc, Jasmina Markovic, Igor Bartenjev, Ivan Vrhovec, Urska Medved, Borut Kocijancic
Pages: 635-639
Published online on: 01 May 2003

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Article

Concomitant chemo-radiotherapy in the treatment of locally advanced and/or metastatic soft tissue sarcomas: Experience of the National Cancer Institute of Genoa

Salvatore Toma, Giuseppe Canavese, Andrea Grimaldi, Giambattista Ravera, Donatella Ugolini, Pierluigi Percivale, Fausto Badellino
Pages: 641-647
Published online on: 01 May 2003

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Article

Time from finding abnormality on mass-screening to final diagnosis of lung cancer

Maki Kanashiki, Hiroaki Satoh, Hiroichi Ishikawa, Yuko T. Yamashita, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 649-652
Published online on: 01 May 2003

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Article

Differences in constitutive and activation-induced expression of CD69 and CD95 between normal and chronic lymphocytic leukemia B cells

Umberto De Fanis, Ciro Romano, Liliana Dalla Mora, Ausilia Sellitto, Salvatore Guastafierro, Angelo Tirelli, Elio Bresciano, Riccardo Giunta, Giacomo Lucivero
Pages: 653-658
Published online on: 01 May 2003

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Article

Epigenetic changes of tumor suppressor genes, P15, P16, VHL and P53 in oral cancer

Kun-Tu Yeh, Jan-Gowth Chang, Ting-Hsu Lin, Yu-Fen Wang, Ni Tien, Jan-Yi Chang, Jui-Chang Chen, Mu-Chin Shih
Pages: 659-663
Published online on: 01 May 2003

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Article

Continuous increase in phosphorylation of cytosolic thymidine kinase during proliferation of rat hepatoma JB1 cells

Ling Lin, Namiko Kuroiwa, Yuichi Moriyama, Shinji Fujimura
Pages: 665-669
Published online on: 01 May 2003

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Article

Effects of p53 gene therapy in radiotherapy or thermotherapy of human head and neck squamous cell carcinoma cell lines

Yuzuru Higuchi, Junichi Asaumi, Jun Murakami, Hidenobu Matsuzaki, Toru Wakasa, Tetsuyoshi Inoue, Hiroshi Shigehara, Hironobu Konouchi, Miki Hisatomi, Shoji Kawasaki, Yoshio Hiraki, Kanji Kishi
Pages: 671-677
Published online on: 01 May 2003

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Article

Clinicopathological study of renal cell carcinoma

Tatsuya Nakatani, Naomasa Yoshida, Hiroyuki Iwata, Katsuyuki Kuratsukuri, Junji Uchida, Hidenori Kawashima, Shinichi Ikemoto, Kazunobu Sugimura
Pages: 679-685
Published online on: 01 May 2003

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Article

Second-line chemotherapy with combined irinotecan and low-dose cisplatin for patients with metastatic gastric carcinoma resistant to 5-fluorouracil

Shinya Shimada, Yasushi Yagi, Masafumi Kuramoto, Norimitsu Aoki, Michio Ogawa
Pages: 687-691
Published online on: 01 May 2003

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Article

Is temporary loop colostomy of the right transverse colon appropriate for complete obstruction by colorectal cancer?

Masaya Mukai, Shinji Himeno, Sayuri Mukoyama, Takayuki Tajima, Yuuki Saito, Isao Ito, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 693-698
Published online on: 01 May 2003

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Article

Promoting effects of high-fat corn oil and high-fat mixed lipid diets on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in F344 rats

Toshiya Kuno, Yoshinobu Hirose, Yasuhiro Yamada, Koujirou Yoshida, Zheng Qiao, Masaki Katayama, Keiko Sakata, Akira Hara, Shigeyuki Sugie, Hideki Mori
Pages: 699-703
Published online on: 01 May 2003

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Article

Arsenic trioxide induces apoptosis in leukemia/lymphoma cell lines via the CD95/CD95L system

Jiebin Zhu, Hirokazu Okumura, Shigeki Ohtake, Shinobu Nakamura, Shinji Nakao
Pages: 705-709
Published online on: 01 May 2003

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Article

P53 codon 72 polymorphism in breast cancer

Nur Buyru, Hatice Tigli, Nejat Dalay
Pages: 711-714
Published online on: 01 May 2003

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Article

A combined analysis of two pivotal randomized trials of a single dose of pegfilgrastim per chemotherapy cycle and daily Filgrastim in patients with stage II-IV breast cancer

Salvatore Siena, Martine J. Piccart, Frankie A. Holmes, John Glaspy, James Hackett, Jennifer J. Renwick
Pages: 715-724
Published online on: 01 May 2003

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Article

Combined treatment with verapamil, a calcium channel blocker, and B428, a synthetic uPA inhibitor, impairs the metastatic ability of a murine mammary carcinoma

Laura B. Todaro, Virginia Ladeda, Elisa Bal de Kier Joffé, Eduardo F. Farías
Pages: 725-732
Published online on: 01 May 2003

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Article

Assessment of circadian rhythms by actimetry in healthy subjects and patients with advanced colorectal cancer

Virginie Chevalier, Marie-Christine Mormont, Hervé Curé, Philippe Chollet
Pages: 733-737
Published online on: 01 May 2003

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Article

Diallyl sulfide inhibits diethylstilbestrol-induced lipid peroxidation in breast tissue of female ACI rats: Implications in breast cancer prevention

Lisa R. Gued, Ronald D. Thomas, Mario Green
Pages: 739-743
Published online on: 01 May 2003

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Article

The modulation of irinotecan-induced diarrhoea and pharmacokinetics by three different classes of pharmacologic agents

Balram Chowbay, Amarnath Sharma, Qing-Yu Zhou, Yin Bun Cheung, Edmund J.D. Lee
Pages: 745-751
Published online on: 01 May 2003

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Article

Regional thermoablation of local or metastatic renal cell carcinoma

Detlef Rohde, Claudia Albers, Andreas Mahnken, Josef Tacke
Pages: 753-757
Published online on: 01 May 2003

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Article

Six-week induction chemotherapy followed by concomitant chemoradiation therapy in stage IV head and neck cancer: A phase II study with organ-sparing purposes

Giovanni Mantovani, Elena Massa, Giorgio Astara, Viviana Murgia, Giulia Gramignano, Luca Ferreli, Paolo Camboni, Maria Rita Lusso, Miria Mocci, Clelia Madeddu, Loredana Mura, Maria Caterina Mudu, Ernesto Proto, Giorgio Tore, Manfredi Mura, Antonio Macciò, Antonello Ferreli, Maurizio Amichetti
Pages: 759-766
Published online on: 01 May 2003

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Article

Inhibition of DES-induced DNA adducts by diallyl sulfide: Implications in liver cancer prevention

Mario Green, Ronald Thomas, Lisa Gued, Sakeenah Sadrud-din
Pages: 767-771
Published online on: 01 May 2003

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Article

Loss of heterozygosity and p53 polymorphism Pro72Arg in a young patient with medulloblastoma

Iacopo Sardi, Laura Giunti, Pierarturo Donati, Laura Lacitignola, Fabio Tucci, Luigi Sardo, Maria Luisa Giovannucci Uzielli, Gabriella Bernini
Pages: 773-775
Published online on: 01 May 2003

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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