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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2003 Volume 10 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Mucinous cystic tumor of the pancreas: Immunohistochemical assessment of ‘ovarian-type stroma’

Akihiko Izumo, Koji Yamaguchi, Takashi Eguchi, Kenichi Nishiyama, Hidetaka Yamamoto, Hirotoshi Yonemasu, Takashi Yao, Masao Tanaka, Masazumi Tsuneyoshi
Pages: 515-525
Published online on: 01 May 2003

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Article

Effect of p27Kip1 on the ability of invasion and metastasis of an oral cancer cell line

Supriatno, Koji Harada, Shinichi Kawaguchi, Hideo Yoshida, Mitsunobu Sato
Pages: 527-532
Published online on: 01 May 2003

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Article

Recurrent malignant Triton tumour: First report on a long time survivor

Wolfgang J. Köstler, Gabriele Amann, Thomas W. Grunt, Christian F. Singer, Sonja M. Schneider, Thomas Brodowicz, Sandra Tomek, Christoph C. Zielinski
Pages: 533-535
Published online on: 01 May 2003

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Article

Silk protein, sericin, suppresses DMBA-TPA-induced mouse skin tumorigenesis by reducing oxidative stress, inflammatory responses and endogenous tumor promoter TNF-α

Siqin Zhaorigetu, Noriyuki Yanaka, Masahiro Sasaki, Hiromitsu Watanabe, Norihisa Kato
Pages: 537-543
Published online on: 01 May 2003

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Article

DNA demethylation is directly related to tumour progression: Evidence in normal, pre-malignant and malignant cells from uterine cervix samples

Adriana De Capoa, Angelina Musolino, Simonetta Della Rosa, Paola Caiafa, Luciano Mariani, Franca Del Nonno, Amina Vocaturo, Raffaele Perrone Donnorso, Alain Niveleau, Claudio Grappelli
Pages: 545-549
Published online on: 01 May 2003

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Article

INI-1, a partner gene of ALL-1, is highly conserved in human acute leukemia

Koshi Mimori, Hiroshi Inoue, Hideshi Ishii, Masaki Mori
Pages: 551-553
Published online on: 01 May 2003

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Article

Alterations of p14ARF and p16INK4a genes in salivary gland carcinomas

Masayoshi Nishimine, Mitsutoshi Nakamura, Munehiro Kishi, Masumi Okamoto, Keiji Shimada, Eiwa Ishida, Tadaaki Kirita, Noboru Konishi
Pages: 555-560
Published online on: 01 May 2003

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Article

Clinical impact of thymidine phosphorylase expression in gastric cancer

Tsuyoshi Noguchi, Shozo Fujiwara, Shinsuke Takeno, Shinya Kai, Akari Mizuta, Yuko Nagao, Yuzo Uchida
Pages: 561-566
Published online on: 01 May 2003

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Article

Expression of matrix metalloproteinases 7 and 2 in human renal cell carcinoma

Toshiyuki Sumi, Tatsuya Nakatani, Hiroyuki Yoshida, Yooji Hyun, Tomoyo Yasui, Yoshinari Matsumoto, Eri Nakagawa, Kazunobu Sugimura, Hidenori Kawashima, Osamu Ishiko
Pages: 567-570
Published online on: 01 May 2003

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Article

BCL2 expression predicts survival in patients receiving synchronous chemoradiotherapy in advanced transitional cell carcinoma of the bladder

S. A. Hussain, R. Ganesan, L. Hiller, P. W. Cooke, P. Murray, L. S. Young, N. D. James
Pages: 571-576
Published online on: 01 May 2003

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Article

Management of Merkel cell carcinoma: Case series of 36 patients

Anja Müller, Ronald Keus, Norbert Neumann, Guido Lammering, Thomas Schnabel
Pages: 577-585
Published online on: 01 May 2003

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Article

Chromosomal aberrations of multiple myeloma in Chinese patients at diagnosis: A study by combined G-banding and multicolor spectral karyotyping

Margaret Heung-Ling Ng, Nathalie Wong, Tai Tap Lau, Kam Sze Tsang, Suk Hang Cheng, Natalie Pui-Ha Chan, Sheung Hang Tang, Kenny Ieng-Kit Lei, Yonna Leung
Pages: 587-591
Published online on: 01 May 2003

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Article

Antitumor activity of new combination chemotherapy with irinotecan hydrochloride and nedaplatin against human cervical cancer cell lines

Kaichiro Yamamoto, Michio Iwahana, Eiji Kumazawa, Koji Kakihata, Kunio Abe, Fuyumi Hirano, Akiko Tohgo, Hiroshi Hoshiai, Kiichiro Noda
Pages: 593-598
Published online on: 01 May 2003

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Article

The role of MTA1 gene expression in human hepatocellular carcinoma

Takayuki Hamatsu, Tatsuya Rikimaru, Yo-Ichi Yamashita, Shinichi Aishima, Shinji Tanaka, Ken Shirabe, Mitsuo Shimada, Yasushi Toh, Keizo Sugimachi
Pages: 599-604
Published online on: 01 May 2003

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Article

Technetium-99m tetrofosmin scintigraphy in pediatric osteogenic sarcoma

Orazio Schillaci, Angela Spanu, Francesco Scopinaro, Francesco Monteleone, Salvatore Masala, Umberto Tarantino, Giuseppe Madeddu, Giovanni Simonetti
Pages: 605-608
Published online on: 01 May 2003

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Article

Expression and regulation patterns of hyaluronidases in small cell lung cancer and glioma lines

Nanna Junker, Scilla Latini, Lone N. Petersen, Paul E.G. Kristjansen
Pages: 609-616
Published online on: 01 May 2003

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Article

Anti-angiogenic activity of conjugated linoleic acid on basic fibroblast growth factor-induced angiogenesis

Eun-Joung Moon, You Mie Lee, Kyu-Won Kim
Pages: 617-621
Published online on: 01 May 2003

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Article

Detection of disseminated cancer cells in rib marrow of patients with esophageal cancer

Tsuyoshi Noguchi, Tomotaka Shibata, Shoichi Fumoto, Tetsuro Sato, Yuzo Uchida, Tsutomu Daa, Shigeo Yokoyama, Helmut E. Gabbert, Wolfram Mueller, Shinsuke Takeno
Pages: 623-627
Published online on: 01 May 2003

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Article

Ionizing radiation and nitric oxide donor sensitize Fas-induced apoptosis via up-regulation of Fas in human cervical cancer cells

In-Chul Park, Sang-Hyeok Woo, Myung-Jin Park, Hyung-Chahn Lee, Su-Jae Lee, Young-Joon Hong, Seung-Hoon Lee, Seok-Il Hong, Chang-Hun Rhee
Pages: 629-633
Published online on: 01 May 2003

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Article

Urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 and type 2 in stage I malignant melanoma

Borut Stabuc, Jasmina Markovic, Igor Bartenjev, Ivan Vrhovec, Urska Medved, Borut Kocijancic
Pages: 635-639
Published online on: 01 May 2003

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Article

Concomitant chemo-radiotherapy in the treatment of locally advanced and/or metastatic soft tissue sarcomas: Experience of the National Cancer Institute of Genoa

Salvatore Toma, Giuseppe Canavese, Andrea Grimaldi, Giambattista Ravera, Donatella Ugolini, Pierluigi Percivale, Fausto Badellino
Pages: 641-647
Published online on: 01 May 2003

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Article

Time from finding abnormality on mass-screening to final diagnosis of lung cancer

Maki Kanashiki, Hiroaki Satoh, Hiroichi Ishikawa, Yuko T. Yamashita, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 649-652
Published online on: 01 May 2003

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Article

Differences in constitutive and activation-induced expression of CD69 and CD95 between normal and chronic lymphocytic leukemia B cells

Umberto De Fanis, Ciro Romano, Liliana Dalla Mora, Ausilia Sellitto, Salvatore Guastafierro, Angelo Tirelli, Elio Bresciano, Riccardo Giunta, Giacomo Lucivero
Pages: 653-658
Published online on: 01 May 2003

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Article

Epigenetic changes of tumor suppressor genes, P15, P16, VHL and P53 in oral cancer

Kun-Tu Yeh, Jan-Gowth Chang, Ting-Hsu Lin, Yu-Fen Wang, Ni Tien, Jan-Yi Chang, Jui-Chang Chen, Mu-Chin Shih
Pages: 659-663
Published online on: 01 May 2003

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Article

Continuous increase in phosphorylation of cytosolic thymidine kinase during proliferation of rat hepatoma JB1 cells

Ling Lin, Namiko Kuroiwa, Yuichi Moriyama, Shinji Fujimura
Pages: 665-669
Published online on: 01 May 2003

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Article

Effects of p53 gene therapy in radiotherapy or thermotherapy of human head and neck squamous cell carcinoma cell lines

Yuzuru Higuchi, Junichi Asaumi, Jun Murakami, Hidenobu Matsuzaki, Toru Wakasa, Tetsuyoshi Inoue, Hiroshi Shigehara, Hironobu Konouchi, Miki Hisatomi, Shoji Kawasaki, Yoshio Hiraki, Kanji Kishi
Pages: 671-677
Published online on: 01 May 2003

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Article

Clinicopathological study of renal cell carcinoma

Tatsuya Nakatani, Naomasa Yoshida, Hiroyuki Iwata, Katsuyuki Kuratsukuri, Junji Uchida, Hidenori Kawashima, Shinichi Ikemoto, Kazunobu Sugimura
Pages: 679-685
Published online on: 01 May 2003

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Article

Second-line chemotherapy with combined irinotecan and low-dose cisplatin for patients with metastatic gastric carcinoma resistant to 5-fluorouracil

Shinya Shimada, Yasushi Yagi, Masafumi Kuramoto, Norimitsu Aoki, Michio Ogawa
Pages: 687-691
Published online on: 01 May 2003

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Article

Is temporary loop colostomy of the right transverse colon appropriate for complete obstruction by colorectal cancer?

Masaya Mukai, Shinji Himeno, Sayuri Mukoyama, Takayuki Tajima, Yuuki Saito, Isao Ito, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 693-698
Published online on: 01 May 2003

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Article

Promoting effects of high-fat corn oil and high-fat mixed lipid diets on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in F344 rats

Toshiya Kuno, Yoshinobu Hirose, Yasuhiro Yamada, Koujirou Yoshida, Zheng Qiao, Masaki Katayama, Keiko Sakata, Akira Hara, Shigeyuki Sugie, Hideki Mori
Pages: 699-703
Published online on: 01 May 2003

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Article

Arsenic trioxide induces apoptosis in leukemia/lymphoma cell lines via the CD95/CD95L system

Jiebin Zhu, Hirokazu Okumura, Shigeki Ohtake, Shinobu Nakamura, Shinji Nakao
Pages: 705-709
Published online on: 01 May 2003

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Article

P53 codon 72 polymorphism in breast cancer

Nur Buyru, Hatice Tigli, Nejat Dalay
Pages: 711-714
Published online on: 01 May 2003

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Article

A combined analysis of two pivotal randomized trials of a single dose of pegfilgrastim per chemotherapy cycle and daily Filgrastim in patients with stage II-IV breast cancer

Salvatore Siena, Martine J. Piccart, Frankie A. Holmes, John Glaspy, James Hackett, Jennifer J. Renwick
Pages: 715-724
Published online on: 01 May 2003

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Article

Combined treatment with verapamil, a calcium channel blocker, and B428, a synthetic uPA inhibitor, impairs the metastatic ability of a murine mammary carcinoma

Laura B. Todaro, Virginia Ladeda, Elisa Bal de Kier Joffé, Eduardo F. Farías
Pages: 725-732
Published online on: 01 May 2003

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Article

Assessment of circadian rhythms by actimetry in healthy subjects and patients with advanced colorectal cancer

Virginie Chevalier, Marie-Christine Mormont, Hervé Curé, Philippe Chollet
Pages: 733-737
Published online on: 01 May 2003

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Article

Diallyl sulfide inhibits diethylstilbestrol-induced lipid peroxidation in breast tissue of female ACI rats: Implications in breast cancer prevention

Lisa R. Gued, Ronald D. Thomas, Mario Green
Pages: 739-743
Published online on: 01 May 2003

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Article

The modulation of irinotecan-induced diarrhoea and pharmacokinetics by three different classes of pharmacologic agents

Balram Chowbay, Amarnath Sharma, Qing-Yu Zhou, Yin Bun Cheung, Edmund J.D. Lee
Pages: 745-751
Published online on: 01 May 2003

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Article

Regional thermoablation of local or metastatic renal cell carcinoma

Detlef Rohde, Claudia Albers, Andreas Mahnken, Josef Tacke
Pages: 753-757
Published online on: 01 May 2003

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Article

Six-week induction chemotherapy followed by concomitant chemoradiation therapy in stage IV head and neck cancer: A phase II study with organ-sparing purposes

Giovanni Mantovani, Elena Massa, Giorgio Astara, Viviana Murgia, Giulia Gramignano, Luca Ferreli, Paolo Camboni, Maria Rita Lusso, Miria Mocci, Clelia Madeddu, Loredana Mura, Maria Caterina Mudu, Ernesto Proto, Giorgio Tore, Manfredi Mura, Antonio Macciò, Antonello Ferreli, Maurizio Amichetti
Pages: 759-766
Published online on: 01 May 2003

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Article

Inhibition of DES-induced DNA adducts by diallyl sulfide: Implications in liver cancer prevention

Mario Green, Ronald Thomas, Lisa Gued, Sakeenah Sadrud-din
Pages: 767-771
Published online on: 01 May 2003

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Article

Loss of heterozygosity and p53 polymorphism Pro72Arg in a young patient with medulloblastoma

Iacopo Sardi, Laura Giunti, Pierarturo Donati, Laura Lacitignola, Fabio Tucci, Luigi Sardo, Maria Luisa Giovannucci Uzielli, Gabriella Bernini
Pages: 773-775
Published online on: 01 May 2003

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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