|
1
|
El-Serag HB: Hepatocellular carcinoma:
recent trends in the United States. Gastroenterology. 127:S27–S34.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Llovet JM, Burroughs A and Bruix J:
Hepatocellular carcinoma. Lancet. 362:1907–1917. 2003. View Article : Google Scholar
|
|
3
|
Shibuya K, Mathers CD, Boschi-Pinto C,
Lopez AD and Murray CJ: Global and regional estimates of cancer
mortality and incidence by site: II. Results for the global burden
of disease 2000. BMC Cancer. 2:372002. View Article : Google Scholar
|
|
4
|
Koike K: Hepatitis B virus HBx gene and
hepatocarcinogenesis. Intervirology. 38:134–142. 1995.PubMed/NCBI
|
|
5
|
Lucito R and Schneider RJ: Hepatitis B
virus X protein activates transcription factor NF-kappa B without a
requirement for protein kinase C. J Virol. 66:983–991.
1992.PubMed/NCBI
|
|
6
|
Kekule AS, Lauer U, Weiss L, Luber B and
Hofschneider PH: Hepatitis B virus transactivator HBx uses a tumour
promoter signalling pathway. Nature. 361:742–745. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Maguire HF, Hoeffler JP and Siddiqui A:
HBV X protein alters the DNA binding specificity of CREB and ATF-2
by protein-protein interactions. Science. 252:842–844. 1991.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Doria M, Klein N, Lucito R and Schneider
RJ: The hepatitis B virus HBx protein is a dual specificity
cytoplasmic activator of Ras and nuclear activator of transcription
factors. EMBO J. 14:4747–4757. 1995.PubMed/NCBI
|
|
9
|
Klein NP and Schneider RJ: Activation of
Src family kinases by hepatitis B virus HBx protein and coupled
signaling to Ras. Mol Cell Biol. 17:6427–6436. 1997.PubMed/NCBI
|
|
10
|
Gottlob K, Fulco M, Levrero M and
Graessmann A: The hepatitis B virus HBx protein inhibits caspase 3
activity. J Biol Chem. 273:33347–33353. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Benn J and Schneider RJ: Hepatitis B virus
HBx protein deregulates cell cycle checkpoint controls. Proc Natl
Acad Sci USA. 92:11215–11219. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ding Q, Xia W, Liu JC, et al: Erk
associates with and primes GSK-3beta for its inactivation resulting
in upregulation of beta-catenin. Mol Cell. 19:159–170. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Benn J and Schneider RJ: Hepatitis B virus
HBx protein activates Ras-GTP complex formation and establishes a
Ras, Raf, MAP kinase signaling cascade. Proc Natl Acad Sci USA.
91:10350–10354. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lee YI, Kang-Park S and Do SI: The
hepatitis B virus-X protein activates a phosphatidylinositol
3-kinase-dependent survival signaling cascade. J Biol Chem.
276:16969–16977. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Artavanis-Tsakonas S, Rand MD and Lake RJ:
Notch signaling: cell fate control and signal integration in
development. Science. 284:770–776. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Miele L: Notch signaling. Clin Cancer Res.
12:1074–1079. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kopan R and Ilagan MX: Gamma-secretase:
proteasome of the membrane? Nat Rev Mol Cell Biol. 5:499–504. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Maillard I, Adler SH and Pear WS: Notch
and the immune system. Immunity. 19:781–791. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Jarriault S, Brou C, Logeat F, Schroeter
EH, Kopan R and Israel A: Signalling downstream of activated
mammalian Notch. Nature. 377:355–358. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ohtsuka T, Sakamoto M, Guillemot F and
Kageyama R: Roles of the basic helix-loop-helix genes Hes-1 and
Hes5 in expansion of neural stem cells of the developing brain. J
Biol Chem. 276:30467–30474. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Miele L, Golde T and Osborne B: Notch
signaling in cancer. Curr Mol Med. 6:905–918. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yanagawa S, Lee JS, Kakimi K, Matsuda Y,
Honjo T and Ishimoto A: Identification of Notch-1 as a frequent
target for provirus insertional mutagenesis in T-cell lymphomas
induced by leukemogenic mutants of mouse mammary tumor virus. J
Virol. 74:9786–9791. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ellisen LW, Bird J, West DC, et al: TAN-1,
the human homolog of the Drosophila notch gene, is broken by
chromosomal translocations in T lymphoblastic neoplasms. Cell.
66:649–661. 1991.PubMed/NCBI
|
|
24
|
Sjolund J, Manetopoulos C, Stockhausen MT
and Axelson H: The Notch pathway in cancer: differentiation gone
awry. Eur J Cancer. 41:2620–2629. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Nijjar SS, Crosby HA, Wallace L, Hubscher
SG and Strain AJ: Notch receptor expression in adult human liver: a
possible role in bile duct formation and hepatic
neovascularization. Hepatology. 34:1184–1192. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Nijjar SS, Wallace L, Crosby HA, Hubscher
SG and Strain AJ: Altered Notch ligand expression in human liver
disease: further evidence for a role of the Notch signaling pathway
in hepatic neovascularization and biliary ductular defects. Am J
Pathol. 160:1695–1703. 2002. View Article : Google Scholar
|
|
27
|
Cheng B, Guo X, Zheng Y, Wang Y, Liu C and
Li P: The effects of HBx gene on the expression of DNA repair
enzymes hOGG1 and hMYHalpha mRNA in HepG2 cells. J Huazhong Univ
Sci Technolog Med Sci. 29:187–192. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Gao J, Chen C, Hong L, et al: Expression
of Jagged-1 and its association with hepatitis B virus X protein in
hepatocellular carcinoma. Biochem Biophys Res Commun. 356:341–347.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Balint K, Xiao M, Pinnix CC, et al:
Activation of Notch-1 signaling is required for
beta-catenin-mediated human primary melanoma progression. J Clin
Invest. 115:3166–3176. 2005. View
Article : Google Scholar : PubMed/NCBI
|
