|
1
|
Hu M and Polyak K: Microenvironmental
regulation of cancer development. Curr Opin Genet Dev. 18:27–34.
2008. View Article : Google Scholar
|
|
2
|
Bissell MJ and Radisky D: Putting tumours
in context. Nat Rev Cancer. 1:46–54. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Radisky D, Hagios C and Bissell MJ: Tumors
are unique organs defined by abnormal signaling and context. Semin
Cancer Biol. 11:87–95. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Klagsbrun M and Soker S: VEGF/VPF: The
angiogenesis factor found? Curr Biol. 3:699–702. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Neufeld G, Cohen T, Gengrinovitch S and
Poltorak Z: Vascular endothelial growth factor (VEGF) and its
receptors. FASEB J. 13:9–22. 1999.PubMed/NCBI
|
|
6
|
Tran J, Rak J, Sheehan C, et al: Marked
induction of the IAP family antiapoptotic proteins survivin and
XIAP by VEGF in vascular endothelial cells. Biochem Biophys Res
Commun. 264:781–788. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ouyang G, Liu M, Ruan K, et al:
Upregulated expression of periostin by hypoxia in non-small-cell
lung cancer cells promotes cell survival via the Akt/PKB pathway.
Cancer Lett. 281:213–219. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Zhang L, Bhojani MS, Ross BD and
Rehemtulla A: Molecular imaging of protein kinases. Cell Cycle.
7:314–317. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhang L, Lee KC, Bhojani MS, et al:
Molecular imaging of Akt kinase activity. Nat Med. 13:1114–1119.
2007. View
Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kunkel MT, Ni Q, Tsien RY, Zhang J and
Newton AC: Spatio-temporal dynamics of protein kinase B/Akt
signaling revealed by a genetically encoded fluorescent reporter. J
Biol Chem. 280:5581–5587. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Harvey RD and Lonial S: PI3 kinase/AKT
pathway as a therapeutic target in multiple myeloma. Future Oncol.
3:639–647. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yang L, Dan HC, Sun M, et al: Akt/protein
kinase B signaling inhibitor-2, a selective small molecule
inhibitor of Akt signaling with antitumor activity in cancer cells
overexpressing Akt. Cancer Res. 64:4394–4399. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Skrzypski M, Kaczmarek P and Le TT:
Effects of orexin A on proliferation, survival, apoptosis and
differentiation of 3T3-L1 preadipocytes into mature adipocytes.
FEBS Lett. 586:4157–4164. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Jin P, Wang YH, Peng YG, Hu S, Lu Q and
Yang LY: Effect of PI3K/AKT inhibitor on benign prostate
hyperplasia and its mechanism: an experimental study. Zhonghua Nan
Ke Xue. 16:1068–1075. 2010.(In Chinese).
|
|
15
|
Zhang HJ, Siu MK, Yeung MC, et al:
Overexpressed PAK4 promotes proliferation, migration and invasion
of choriocarcinoma. Carcinogenesis. 32:765–771. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yang Q, Liu HY, Zhang YW, et al:
Anandamide induces cell death through lipid rafts in hepatic
stellate cells. J Gastroenterol Hepatol. 25:991–1001. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Altieri DC and Marchisio C: Survivin
apoptosis: an interloper between cell death and cell proliferation
in cancer. Lab Invest. 79:1327–1333. 1999.PubMed/NCBI
|
|
18
|
Yamamoto T and Tanigawa N: The role of
survivin as a new target of diagnosis and treatment in human
cancer. Med Electron Microsc. 34:207–212. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tamm I, Want Y, Sausville E, et al:
IAP-family protein survivin inhibits caspase activity and apoptosis
induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer
Res. 58:5315–5320. 1998.PubMed/NCBI
|
|
20
|
Altieri DC: Survivin versatile modulation
of cell division and apoptosis in cancer. Oncogene. 22:8581–8589.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kajiwara Y, Yamasaki F, Hama S, et al:
Exression of survivin in astrocytic tumors: correlation with
malignant grade and prognosis. Cancer. 97:1077–1083. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Islam A, Kageyama H, Takada N, et al: High
expression of survivin, mapped to 17q25, is significantly
associated with poor prognostic factors and promotes cell survival
in human neuroblastoma. Oncogene. 19:617–623. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ambrosini G, Adida C and Altieri D: A
novel anti-apoptosis gene, survivin, expressed in cancer and
lymphoma. Nat Med. 3:917–921. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ngan CY, Yamamoto H, Takagi A, et al:
Oxaliplatin induces mitotic catastrophe and apoptosis in esophageal
cancer cells. Cancer Sci. 99:129–139. 2008.PubMed/NCBI
|
|
25
|
Huang CK, Lee SO, Lai KP, et al: Targeting
androgen receptor in bone marrow mesenchymal stem cells leads to
better transplantation therapy efficacy in liver cirrhosis.
Hepatology. 57:1550–1563. 2013. View Article : Google Scholar
|
|
26
|
Hanahan D and Weinberg RA: The hallmarks
of cancer. Cell. 100:57–70. 2000. View Article : Google Scholar
|
|
27
|
Hahn WC and Weinberg RA: Modelling the
molecular circuitry of cancer. Nat Rev Cancer. 2:331–341. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
López-Maury L, Marguerat S and Bähler J:
Tuning gene expression to changing environments: from rapid
responses to evolutionary adaptation. Nat Rev Genet. 9:583–593.
2008.PubMed/NCBI
|
|
29
|
Tateishi M, Ishida T, Mitsudomi T, Kaneko
S and Sugimachi K: Immunohistochemical evidence of autocrine growth
factors in adenocarcinoma of the human lung. Cancer Res.
50:7077–7080. 1990.PubMed/NCBI
|
|
30
|
Brattstrom D, Bergqvist M, Hesselius P,
Larsson A, Wagenius G and Brodin O: Serum VEGF and bFGF adds
prognostic information in patients with normal platelet counts when
sampled before, during and after treatment for locally advanced
non-small cell lung cancer. Lung Cancer. 43:55–62. 2004. View Article : Google Scholar
|
|
31
|
Sufen G, Xianghong Y, Yongxia C and Qian
P: bFGF and PDGF-BB have a synergistic effect on the proliferation,
migration and VEGF release of endothelial progenitor cells. Cell
Biol Int. 35:545–551. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Drevs J, Zirrgiebel U and Schmidt-Gersbach
CI: Soluble markers for the assessment of biological activity with
PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor
receptor (VEGFR) tyrosine kinase inhibitor in patients with
advanced colorectal cancer from two phase I trials. Ann Oncol.
16:558–565. 2005. View Article : Google Scholar
|
|
33
|
Feng X, Zhang B, Wang J, et al:
Adenovirus-mediated transfer of siRNA against basic fibroblast
growth factor mRNA enhances the sensitivity of glioblastoma cells
to chemotherapy. Med Oncol. 28:24–30. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang H, Rubin M, Fenig E, et al: Basic
fibroblast growth factor causes growth arrest in MCF-7 human breast
cancer cells while inducing both mitogenic and inhibitory G1
events. Cancer Res. 57:1750–1757. 1997.PubMed/NCBI
|
|
35
|
Shankland SJ, Pippin J, Flanagan M, et al:
Mesangial cell proliferation mediated by PDGF and bFGF is
determined by levels of the cyclin kinase inhibitor p27Kip1. Kidney
Int. 51:1088–1099. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Johnson MR, Valentine C, Basilio C and
Mansukhani A: FGF signaling activates STAT1 and p21 and inhibits
the estrogen response and proliferation of MCF-7 cells. Oncogene.
16:2647–2656. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Carmeliet P, Lampugnani MG, Moons L, et
al: Targeted deficiency or cytosolic truncation of the VE-cadherin
gene in mice impairs VEGF-mediated endothelial survival and
angiogenesis. Cell. 98:147–157. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kim JW, Ho WJ and Wu BM: The role of the
3D environment in hypoxia-induced drug and apoptosis resistance.
Anticancer Res. 31:3237–3245. 2011.PubMed/NCBI
|
|
39
|
Gerber HP, Dixit V and Ferrara N: Vascular
endothelial growth factor induces expression of the antiapoptotic
proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem.
273:13313–13316. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Gerber HP, McMurtrey A, Kowalski J, Yan M,
Keyt BA, Dixit V and Ferrara N: Vascular endothelial growth factor
regulates endothelial cell survival through the
phosphatidylinositol 3′-kinase/Akt signal transduction pathway.
Requirement for Flk-1/KDR activation. J Biol Chem. 273:30336–30343.
1998.
|
|
41
|
Li F, Ambrosini G, Chu EY, Plescia J, et
al: Control of apoptosis and mitotic spindle checkpoint by
survivin. Nature. 396:580–584. 1998. View
Article : Google Scholar : PubMed/NCBI
|
