Journal Articles
Review
Tumor suppressor genes associated with drug resistance in ovarian cancer (Review)
Fuqiang Yin, Xia Liu, Danrong Li, Qi Wang, Wei Zhang, Li Li
Pages: 3-10 Published online on: 09 May 2013
Article
Functional polymorphism in the 5'-UTR of CR2 is associated with susceptibility to nasopharyngeal carcinoma
Qin Fan, Jun-Fang He, Qi-Rui Wang, Hong-Bing Cai, Xue-Gang Sun, Xin-Xi Zhou, Hai-De Qin, Yin Yao Shugart, Wei-Hua Jia
Pages: 11-16 Published online on: 23 April 2013
Article
High expression of microRNA-155 is associated with the aggressive malignant behavior of gallbladder carcinoma
Hiroshi Kono, Masafumi Nakamura, Takao Ohtsuka, Yosuke Nagayoshi, Yasuhisa Mori, Shunichi Takahata, Shinichi Aishima, Masao Tanaka
Pages: 17-24 Published online on: 09 May 2013
Article
Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer
Tomoko Yoneda, Ayumi Kuboyama, Kiyoko Kato, Tatsuhiro Ohgami, Kanako Okamoto, Toshiaki Saito, Norio Wake
Pages: 25-34 Published online on: 29 April 2013
Article
The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis
Valerie Francescutti, Louis Rivera, Mukund Seshadri, Minhyung Kim, Michelle Haslinger, Marta Camoriano, Kristopher Attwood, John M. Kane , Joseph J. Skitzki
Pages: 35-42 Published online on: 15 May 2013
Article
Characteristics and prognosis of gastric cancer in young patients
Taro Isobe, Kousuke Hashimoto, Junya Kizaki, Motoshi Miyagi, Keishiro Aoyagi, Kikuo Koufuji, Kazuo Shirouzu
Pages: 43-49 Published online on: 15 May 2013
Article
Role of the ERas gene in gastric cancer cells
Yang Liu, Zhaoqian Wang, Huiming Li, Zhaoping Wu, Fang Wei, Huiping Wang
Pages: 50-56 Published online on: 23 April 2013
Article
Biological characteristics of CD133+ cells in nasopharyngeal carcinoma
Hui-Wen Zhuang, Ting-Ting Mo, Wei-Jian Hou, Guan-Xia Xiong, Xiao-Lin Zhu, Qing-Ling Fu, Wei-Ping Wen
Pages: 57-63 Published online on: 22 April 2013
Article
Promotive effects of cell proliferation and chromosomal instability induced by tribbles-related protein 3 in mouse mammary tumor cells
Yuto Sakai, Katsumi Fukamachi, Mitsuru Futakuchi, Hidetoshi Hayashi, Masumi Suzui
Pages: 64-70 Published online on: 30 April 2013
Article
Establishment and characterization of novel cell lines and xenografts from patients with gastrointestinal stromal tumors
Kazumasa Fukuda, Yoshiro Saikawa, Hiroyuki Sako, Yumi Yoshimura, Tsunehiro Takahashi, Norihito Wada, Hirohumi Kawakubo, Hiroya Takeuchi, Tai Ohmori, Yuko Kitagawa
Pages: 71-78 Published online on: 25 April 2013
Article
Investigation of the clinicopathological features of fallopian tube malignancy
Yoshihito Yokoyama, Masayuki Futagami, Toshio Fujimoto, Yukihiro Terada, Eriko Takatori, Toru Sugiyama, Takeo Otsuki, Nobuo Yaegashi, Takanobu Kojimahara, Hirohisa Kurachi, Hiroshi Nishiyama, Keiya Fujimori, Toru Tase, Hideki Mizunuma
Pages: 79-84 Published online on: 30 April 2013
Article
The efficacy and safety of prophylactic closure for a large mucosal defect after colorectal endoscopic submucosal dissection
Shintaro Fujihara, Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Mitsuyoshi Kobayashi, Kazi Rafiq, Tsutomu Masaki
Pages: 85-90 Published online on: 14 May 2013
Article
Lack of correlation between the antibody to hepatitis B core antigen and survival after surgical resection for hepatitis C virus-related hepatocellular carcinoma
Hiroki Nishikawa, Akira Arimoto, Tomoko Wakasa, Ryuichi Kita, Toru Kimura, Yukio Osaki
Pages: 91-98 Published online on: 24 April 2013
Article
Protein-bound polysaccharide-K induces apoptosis via mitochondria and p38 mitogen‑activated protein kinase‑dependent pathways in HL‑60 promyelomonocytic leukemia cells
Noriyuki Hirahara, Takeo Edamatsu, Ayako Fujieda, Masaki Fujioka, Tsutomu Wada, Yoshitsugu Tajima
Pages: 99-104 Published online on: 22 April 2013
Article
Transmembrane receptor CXCR7 increases the risk of extrahepatic metastasis of relatively well-differentiated hepatocellular carcinoma through upregulation of osteopontin
Tong-Chun Xue, Rong-Xin Chen, Zheng-Gang Ren, Jing-Huai Zou, Zhao-You Tang, Sheng-Long Ye
Pages: 105-110 Published online on: 01 May 2013
Article
S100 calcium-binding protein A4 is a novel independent prognostic factor for the poor prognosis of gastric carcinomas
Ying Zhao, Tianbiao Zhang, Qiang Wang
Pages: 111-118 Published online on: 23 April 2013
Article
Correlation of TP53 mutations with HCV positivity in hepatocarcinogenesis: Identification of a novel TP53 microindel in hepatocellular carcinoma with HCV infection
Jiang Long, Yan Wang, Man Li, Wei-Min Tong, Ji-Dong Jia, Jian Huang
Pages: 119-124 Published online on: 26 April 2013
Article
SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein
Shou-Jen Kuo, Hui-Yi Lin, Su-Yu Chien, Dar-Ren Chen
Pages: 125-130 Published online on: 15 May 2013
Article
Estrogen receptor-β expression and pharmacological targeting in bladder cancer
Eric C. Kauffman, Brian D. Robinson, Martin Downes, Katarzyna Marcinkiewicz, Srinivas Vourganti, Douglas S. Scherr, Lorraine J. Gudas, Nigel P. Mongan
Pages: 131-138 Published online on: 23 April 2013
Article
Crizotinib may be used in lewis lung carcinoma: A novel use for crizotinib
Pu Xia, Wen-Feng Gou, Shuang Zhao, Hua-Chuan Zheng
Pages: 139-148 Published online on: 24 April 2013
Article
Inhibition of pancreatic cancer and potentiation of gemcitabine effects by the extract of Pao Pereira
Jun Yu, Jeanne Drisko, Qi Chen
Pages: 149-156 Published online on: 14 May 2013
Article
Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model
Xiang-Jun Ji, Sui-Hua Chen, Lin Zhu, Hao Pan, Yuan Zhou, Wei Li, Wan-Chun You, Chao-Chao Gao, Jian-Hong Zhu, Kuan Jiang, Han-Dong Wang
Pages: 157-164 Published online on: 15 May 2013
Article
STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer
Jie Li, Geng Cui, Lu Sun, Shu-Juan Wang, Ya-Li Li, Yuan-Guang Meng, Zheng Guan, Wen-Sheng Fan, Li-An Li, Yi-Zhuo Yang, Yan-Qin You, Xiao-Yu Fu, Zhi-Feng Yan, Ke Huang
Pages: 165-170 Published online on: 22 April 2013
Article
Knockdown of interferon-induced transmembrane protein 3 expression suppresses breast cancer cell growth and colony formation and affects the cell cycle
Mei Yang, Hongwen Gao, Peng Chen, Jiaoyuan Jia, Shan Wu
Pages: 171-178 Published online on: 26 April 2013
Article
Specific reversal of tumor-suppressor gene promoter hypermethylation with bovine oocyte extract
Zhenfei Wang, Haixia Gao, Huimin Wang, Xiaolu Ren, Luri Bao, Rula Sa, Jie Wang, Haidong Bai, Haiquan Yu
Pages: 179-184 Published online on: 10 May 2013
Article
Epigenetic silencing of Bcl-2, CEBPA and p14ARF by the AML1-ETO oncoprotein contributing to growth arrest and differentiation block in the U937 cell line
Wen-Yue Zhuang, Jian-Nong Cen, Yun Zhao, Zi-Xing Chen
Pages: 185-192 Published online on: 14 May 2013
Article
Downregulation of BMP6 enhances cell proliferation and chemoresistance via activation of the ERK signaling pathway in breast cancer
Wen-Jing Lian, Geng Liu, Yuan-Jie Liu, Zhi-Wei Zhao, Tao Yi, Hong-Ying Zhou
Pages: 193-200 Published online on: 14 May 2013
Article
OCT4 is epigenetically regulated by DNA hypomethylation of promoter and exon in primary gliomas
Jinlong Shi, Wei Shi, Lanchun Ni, Xide Xu, Xing Su, Liang Xia, Feng Xu, Jian Chen, Jianhong Zhu
Pages: 201-206 Published online on: 13 May 2013
Article
Molecular characteristics of homologous salivary adenoid cystic carcinoma cell lines with different lung metastasis ability
Lin Wang, Yixiang Wang, Huan Bian, Yinfei Pu, Chuanbin Guo
Pages: 207-212 Published online on: 14 May 2013
Article
Silencing of pancreatic adenocarcinoma upregulated factor by RNA interference inhibits the malignant phenotypes of human colorectal cancer cells
Peng-Fei Liu, Yun-Yun Wu, You Hu, Lei Wang, Song-Bing He, Yi-Bei Zhu, Xin-Guo Zhu
Pages: 213-220 Published online on: 15 May 2013
Article
The in vitro antitumor activity of Siegesbeckia glabrescens against ovarian cancer through suppression of receptor tyrosine kinase expression and the signaling pathways
Young-Rak Cho, Shin Wook Choi, Dong-Wan Seo
Pages: 221-226 Published online on: 15 May 2013
Article
Indole-3-carbinol inhibits cell proliferation and induces apoptosis in Hep-2 laryngeal cancer cells
Ya-Qiu Wang, Chen Chen, Zhe Chen, Yong Xu, Yan Wang, Bo-Kui Xiao, Shi-Ming Chen, Ze-Zhang Tao
Pages: 227-233 Published online on: 22 April 2013
Article
Melanoma antigen gene family A as a molecular marker of gastric and colorectal cancers
Tae-Bum Lee, Sung-Chul Lim, Young-Sook Moon, Cheol-Hee Choi
Pages: 234-238 Published online on: 14 May 2013
Article
A new curcumin analogue exhibits enhanced antitumor activity in nasopharyngeal carcinoma
Yunbao Pan, Jian Xiao, Guang Liang, Mengyao Wang, Dujuan Wang, Sumei Wang, Huiling Yang
Pages: 239-245 Published online on: 14 May 2013
Article
Treatment of 131I-labeled anti-CD147 monoclonal antibody in VX2 carcinoma-induced liver tumors
Huanzhang Niu, Ruihua Wang, Jingliang Cheng, Shegan Gao, Baoping Liu
Pages: 246-252 Published online on: 23 April 2013
Article
The role of CDK1 in apoptin-induced apoptosis in hepatocellular carcinoma cells
Jing Zhao, Su-Xia Han, Jin-Lu Ma, Xia Ying, Peijun Liu, Juan Li, Lijuan Wang, Ying Zhang, Jiguang Ma, Li Zhang, Qing Zhu
Pages: 253-259 Published online on: 25 April 2013
Article
Expression of human full-length MUC1 inhibits the proliferation and migration of a B16 mouse melanoma cell line
Fengli Wang, Qiongshu Li, Weihua Ni, Fang Fang, Xiaxia Sun, Fei Xie, Juan Wang, Fang Wang, Sujun Gao, Guixiang Tai
Pages: 260-268 Published online on: 30 April 2013
Article
Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Huawei Cai, Fangyu Peng
Pages: 269-275 Published online on: 29 April 2013
Article
Diagnostic and biological significance of microRNA-192 in pancreatic ductal adenocarcinoma
Chenyan Zhao, Jing Zhang, Shuhui Zhang, Danghui Yu, Ying Chen, Qinghua Liu, Min Shi, Canrong Ni, Minghua Zhu
Pages: 276-284 Published online on: 23 April 2013
Article
Differential expression of cell adhesion molecules in an ionizing radiation-induced breast cancer model system
Gloria M. Calaf, Debasish Roy, Gopeshwar Narayan, Adayabalam S. Balajee
Pages: 285-291 Published online on: 10 May 2013
Article
Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways
Jian-Li Gao, Gui-Yuan Lv, Bai-Cheng He, Bing-Qiang Zhang, Hongyu Zhang, Ning Wang, Chong-Zhi Wang, Wei Du, Chun-Su Yuan, Tong-Chuan He
Pages: 292-298 Published online on: 30 April 2013
Article
Spontaneous clearance of Helicobacter pylori after pylorus-preserving gastrectomy for gastric cancer
Tomoharu Miyashita, Koichi Miwa, Masafumi Inokuchi, Hisatoshi Nakagawara, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Takanori Hattori, Tetsuo Ohta
Pages: 299-303 Published online on: 15 May 2013
Article
Raf kinase inhibitor protein inhibits esophageal cancer cell invasion through downregulation of matrix metalloproteinase expression
Dongqiang Zhao, Junji Ma, Junli Shi, Lijuan Cheng, Fangfang Li, Xiaoyu Jiang, Huiqing Jiang
Pages: 304-312 Published online on: 14 May 2013
Article
Overexpression of Numb suppresses tumor cell growth and enhances sensitivity to cisplatin in epithelioid malignant pleural mesothelioma
Yanmeng Kang, Mingjie Ding, Guangyan Tian, Haisheng Guo, Yunyan Wan, Zhouhong Yao, Bin Li, Dianjie Lin
Pages: 313-319 Published online on: 26 April 2013
Article
microRNA expression profile in stage III colorectal cancer: Circulating miR-18a and miR-29a as promising biomarkers
Anna Brunet Vega, Carles Pericay, Irene Moya, Anna Ferrer, Emma Dotor, Aleydis Pisa, Àlex Casalots, Xavier Serra-Aracil, Joan-Carles Oliva, Anna Ruiz, Eugeni Saigí
Pages: 320-326 Published online on: 15 May 2013
Article
microRNA-330 inhibits cell motility by downregulating Sp1 in prostate cancer cells
Yeqing Mao, Hong Chen, Yiwei Lin, Xin Xu, Zhenghui Hu, Yi Zhu, Jian Wu, Xianglai Xu, Xiangyi Zheng, Liping Xie
Pages: 327-333 Published online on: 13 May 2013
Article
Search for mutations in signaling pathways in head and neck squamous cell carcinoma
Thais Gulim De Carvalho, Ana Carolina De Carvalho, Danielle Calheiros Campelo Maia, Juliana Kaori Ogawa, Andre Lopes Carvalho, Andre Luiz Vettore
Pages: 334-340 Published online on: 13 May 2013
Article
Identification of integrin β1 as a prognostic biomarker for human lung adenocarcinoma using 2D-LC‑MS/MS combined with iTRAQ technology
Peng-Fei Zhang, Gu-Qing Zeng, Lun-Zhao Yi, Jian-Ping Liu, Xun‑Xun Wan, Jia-Quan Qu, Jian-Huang Li, Cui Li, Can-E Tang, Rong Hu, Xu Ye, Yu Chen, Zhu-Chu Chen, Zhi-Qiang Xiao
Pages: 341-349 Published online on: 15 May 2013
Article
Magnifying narrow-band imaging of surface patterns for diagnosing colorectal cancer
Masashi Misawa, Shin-Ei Kudo, Yoshiki Wada, Hiroki Nakamura, Naoya Toyoshima, Seiko Hayashi, Yuichi Mori, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Fuyuhiko Yamamura, Shigeharu Hamatani
Pages: 350-356 Published online on: 15 May 2013
Article
Quercetin synergizes with 2-methoxyestradiol inhibiting cell growth and inducing apoptosis in human prostate cancer cells
Guodong Wang, Liming Song, Huiping Wang, Nianzeng Xing
Pages: 357-363 Published online on: 15 May 2013
Article
Downregulation of aryl hydrocarbon receptor expression decreases gastric cancer cell growth and invasion
Xiao-Fei Yin, Jie Chen, Wei Mao, Yu-Hong Wang, Min-Hu Chen
Pages: 364-370 Published online on: 22 April 2013
Article
Human papillomavirus predicts the outcome following concomitant chemoradiotherapy in patients with head and neck squamous cell carcinomas
Anaëlle Duray, Géraldine Descamps, Christine Decaestecker, Nicolas Sirtaine, André Gilles, Mohamad Khalifé, Gilbert Chantrain, Christophe E. Depuydt, Philippe Delvenne, Sven Saussez
Pages: 371-376 Published online on: 22 April 2013
Article
Inhibition of CK2 enhances UV-triggered apoptotic cell death in lung cancer cell lines
Tiesuo Zhao, Huijie Jia, Lifei Li, Guoliang Zhang, Min Zhao, Qian Cheng, Junnian Zheng, Di Li
Pages: 377-384 Published online on: 18 April 2013
Article
Basic fibroblast growth factor upregulates survivin expression in hepatocellular carcinoma cells via a protein kinase B-dependent pathway
Bo Sun, Haiyan Xu, Gang Zhang, Yongbao Zhu, Hukui Sun, Guihua Hou
Pages: 385-390 Published online on: 15 May 2013
Article
Intrathecal administration of cyclic AMP response element-binding protein-antisense oligonucleotide attenuates neuropathic pain after peripheral nerve injury and decreases the expression of N-Methyl-D-Aspartic receptors in mice
Xiaoping Gu, Jinhua Bo, Wei Zhang, Xiaofeng Sun, Juan Zhang, Yan Yang, Zhengliang Ma
Pages: 391-398 Published online on: 30 April 2013
Article
miR-449b inhibits the proliferation of SW1116 colon cancer stem cells through downregulation of CCND1 and E2F3 expression
Yantian Fang, Xiaodong Gu, Zhengyang Li, Jianbin Xiang, Zongyou Chen
Pages: 399-406 Published online on: 14 May 2013
Article
Human hsp70 and HPV16 oE7 fusion protein vaccine induces an effective antitumor efficacy
Jinbao Zong, Changyuan Wang, Bin Liu, Mingjun Liu, Yongxian Cao, Xiufang Sun, Yuan Yao, Guirong Sun
Pages: 407-412 Published online on: 09 May 2013
Article
Combination of GHRH antagonists and docetaxel shows experimental effectiveness for the treatment of triple-negative breast cancers
S. Seitz, F. G. Rick, A. V. Schally, A. Treszl, F. Hohla, L. Szalontay, M. Zarandi, O. Ortmann, J. B. Engel, S. Buchholz
Pages: 413-418 Published online on: 29 April 2013
Article
Extracellular signal-regulated kinase 2 mediates the expression of granulocyte colony-stimulating factor in invasive cancer cells
Chia-Huei Lee, Szu-Han Lin, Shwu-Fen Chang, Po-Yuan Chang, Zhi-Ping Yang, Shao-Chun Lu
Pages: 419-424 Published online on: 14 May 2013
Article
4-Chlorobenzoyl berbamine, a novel berbamine derivative, induces apoptosis in multiple myeloma cells through the IL-6 signal transduction pathway and increases FOXO3a-Bim expression
Jia-Kun Shen, Hua-Ping Du, Qiuling Ma, Min Yang, Yun-Gui Wang, Jie Jin
Pages: 425-432 Published online on: 26 April 2013
Article
Enhanced autophagic flux by endoplasmic reticulum stress in human hepatocellular carcinoma cells contributes to the maintenance of cell viability
Tai Ma, Yuan-Yuan Li, Jie Zhu, Lu-Lu Fan, Wei-Dong Du, Chang-Hao Wu, Guo-Ping Sun, Jia-Bin Li
Pages: 433-440 Published online on: 15 May 2013
Article
Validity of bone marker measurements for monitoring response to bisphosphonate therapy with zoledronic acid in metastatic breast cancer
Bahriye Aktas, Sabine Kasimir-Bauer, Nils Lehmann, Rainer Kimmig, Mitra Tewes
Pages: 441-447 Published online on: 22 April 2013
Article
NK4 regulates 5-fluorouracil sensitivity in cholangiocarcinoma cells by modulating the intrinsic apoptosis pathway
Xianxiu Ge, Youli Wang, Quanpeng Li, Hong Yu, Guozhong Ji, Lin Miao
Pages: 448-454 Published online on: 25 April 2013
Article
Association between lymphoma prognosis and aberrant methylation of ID4 and ZO-1 in bone marrow and paraffin-embedded lymphoma tissues of treatment-naive patients
Jian Cen, Jianliang Shen, Xinrong Wang, Huiyuan Kang, Lili Wang, Lu Sun, Yonghui Li, Li Yu
Pages: 455-461 Published online on: 10 May 2013
Article
Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells
Andreas Eisenreich, Andreas Zakrzewicz, Kilian Huber, Hannes Thierbach, Wojciech Pepke, Petra Goldin-Lang, Heinz-Peter Schultheiss, Axel Pries, Ursula Rauch
Pages: 462-470 Published online on: 22 April 2013
Article
Pre-activation of the p53 pathway through Nutlin-3a sensitises sarcomas to drozitumab therapy
Kathleen I. Pishas, Susan J. Neuhaus, Mark T. Clayer, Alaknanda Adwal, Michael P. Brown, Andreas Evdokiou, David F. Callen, Paul M. Neilsen
Pages: 471-477 Published online on: 13 May 2013
Article
Cytochalasin D promotes pulmonary metastasis of B16 melanoma through expression of tissue factor
Feng-Ying Huang, Wen-Li Mei, Guang-Hong Tan, Hao-Fu Dai, Yue-Nan Li, Jun-Li Guo, Yong-Hao Huang, Huan-Ge Zhao, Hua Wang, Song-Lin Zhou, Ying-Ying Lin
Pages: 478-484 Published online on: 24 April 2013
Article
Low-dose 1,25-dihydroxyvitamin D3 combined with arsenic trioxide synergistically inhibits proliferation of acute myeloid leukemia cells by promoting apoptosis
Ji-Yeon Bae, Ji-Won Kim, Inho Kim
Pages: 485-491 Published online on: 09 May 2013
Article
miR-150, p53 protein and relevant miRNAs consist of a regulatory network in NSCLC tumorigenesis
De-Tao Wang, Zhong-Liang Ma, Yan-Li Li, Yue-Qing Wang, Bo-Tao Zhao, Jia-Li Wei, Xiang Qi, Xin-Tai Zhao, You-Xin Jin
Pages: 492-498 Published online on: 13 May 2013
Article
Antitumor effects of a novel histone deacetylase inhibitor NK-HDAC-1 on breast cancer
Zhong-Hua Li, Xiao-Bing Zhang, Xi-Qian Han, Cong-Ran Feng, Feng‑Shan Wang, Peng George Wang, Jie Shen, Yi-Kang Shi
Pages: 499-505 Published online on: 29 April 2013
Article
RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK
Ji Hoon Jang, Seon Min Woo, Hee Jung Um, Eun Jung Park, Kyoung-Jin Min, Tae-Jin Lee, Sang Hyun Kim, Yung Hyun Choi, Taeg Kyu Kwon
Pages: 506-512 Published online on: 26 April 2013
Article
MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion
Woo Hyun Park, Suhn Hee Kim
Pages: 513-519 Published online on: 09 May 2013
Article