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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2013 Volume 30 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Tumor suppressor genes associated with drug resistance in ovarian cancer (Review)

Fuqiang Yin, Xia Liu, Danrong Li, Qi Wang, Wei Zhang, Li Li
Pages: 3-10
Published online on: 09 May 2013

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Article Open Access

Functional polymorphism in the 5'-UTR of CR2 is associated with susceptibility to nasopharyngeal carcinoma

Qin Fan, Jun-Fang He, Qi-Rui Wang, Hong-Bing Cai, Xue-Gang Sun, Xin-Xi Zhou, Hai-De Qin, Yin Yao Shugart, Wei-Hua Jia
Pages: 11-16
Published online on: 23 April 2013

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Article Open Access

High expression of microRNA-155 is associated with the aggressive malignant behavior of gallbladder carcinoma

Hiroshi Kono, Masafumi Nakamura, Takao Ohtsuka, Yosuke Nagayoshi, Yasuhisa Mori, Shunichi Takahata, Shinichi Aishima, Masao Tanaka
Pages: 17-24
Published online on: 09 May 2013

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Article Open Access

Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer

Tomoko Yoneda, Ayumi Kuboyama, Kiyoko Kato, Tatsuhiro Ohgami, Kanako Okamoto, Toshiaki Saito, Norio Wake
Pages: 25-34
Published online on: 29 April 2013

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Article Open Access

The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis

Valerie Francescutti, Louis Rivera, Mukund Seshadri, Minhyung Kim, Michelle Haslinger, Marta Camoriano, Kristopher Attwood, John M. Kane , Joseph J. Skitzki
Pages: 35-42
Published online on: 15 May 2013

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Article Open Access

Characteristics and prognosis of gastric cancer in young patients

Taro Isobe, Kousuke Hashimoto, Junya Kizaki, Motoshi Miyagi, Keishiro Aoyagi, Kikuo Koufuji, Kazuo Shirouzu
Pages: 43-49
Published online on: 15 May 2013

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Article Open Access

Role of the ERas gene in gastric cancer cells

Yang Liu, Zhaoqian Wang, Huiming Li, Zhaoping Wu, Fang Wei, Huiping Wang
Pages: 50-56
Published online on: 23 April 2013

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Article Open Access

Biological characteristics of CD133+ cells in nasopharyngeal carcinoma

Hui-Wen Zhuang, Ting-Ting Mo, Wei-Jian Hou, Guan-Xia Xiong, Xiao-Lin Zhu, Qing-Ling Fu, Wei-Ping Wen
Pages: 57-63
Published online on: 22 April 2013

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Article

Promotive effects of cell proliferation and chromosomal instability induced by tribbles-related protein 3 in mouse mammary tumor cells

Yuto Sakai, Katsumi Fukamachi, Mitsuru Futakuchi, Hidetoshi Hayashi, Masumi Suzui
Pages: 64-70
Published online on: 30 April 2013

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Article

Establishment and characterization of novel cell lines and xenografts from patients with gastrointestinal stromal tumors

Kazumasa Fukuda, Yoshiro Saikawa, Hiroyuki Sako, Yumi Yoshimura, Tsunehiro Takahashi, Norihito Wada, Hirohumi Kawakubo, Hiroya Takeuchi, Tai Ohmori, Yuko Kitagawa
Pages: 71-78
Published online on: 25 April 2013

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Article

Investigation of the clinicopathological features of fallopian tube malignancy

Yoshihito Yokoyama, Masayuki Futagami, Toshio Fujimoto, Yukihiro Terada, Eriko  Takatori, Toru Sugiyama, Takeo Otsuki, Nobuo Yaegashi, Takanobu Kojimahara, Hirohisa Kurachi, Hiroshi Nishiyama, Keiya Fujimori, Toru Tase, Hideki Mizunuma
Pages: 79-84
Published online on: 30 April 2013

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Article

The efficacy and safety of prophylactic closure for a large mucosal defect after colorectal endoscopic submucosal dissection

Shintaro Fujihara, Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Mitsuyoshi Kobayashi, Kazi Rafiq, Tsutomu Masaki
Pages: 85-90
Published online on: 14 May 2013

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Article

Lack of correlation between the antibody to hepatitis B core antigen and survival after surgical resection for hepatitis C virus-related hepatocellular carcinoma

Hiroki Nishikawa, Akira Arimoto, Tomoko Wakasa, Ryuichi Kita, Toru Kimura, Yukio Osaki
Pages: 91-98
Published online on: 24 April 2013

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Article

Protein-bound polysaccharide-K induces apoptosis via mitochondria and p38 mitogen‑activated protein kinase‑dependent pathways in HL‑60 promyelomonocytic leukemia cells

Noriyuki Hirahara, Takeo Edamatsu, Ayako Fujieda, Masaki Fujioka, Tsutomu Wada, Yoshitsugu Tajima
Pages: 99-104
Published online on: 22 April 2013

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Article

Transmembrane receptor CXCR7 increases the risk of extrahepatic metastasis of relatively well-differentiated hepatocellular carcinoma through upregulation of osteopontin

Tong-Chun Xue, Rong-Xin Chen, Zheng-Gang Ren, Jing-Huai Zou, Zhao-You Tang, Sheng-Long Ye
Pages: 105-110
Published online on: 01 May 2013

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Article

S100 calcium-binding protein A4 is a novel independent prognostic factor for the poor prognosis of gastric carcinomas

Ying Zhao, Tianbiao Zhang, Qiang Wang
Pages: 111-118
Published online on: 23 April 2013

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Article

Correlation of TP53 mutations with HCV positivity in hepatocarcinogenesis: Identification of a novel TP53 microindel in hepatocellular carcinoma with HCV infection

Jiang Long, Yan Wang, Man Li, Wei-Min Tong, Ji-Dong Jia, Jian Huang
Pages: 119-124
Published online on: 26 April 2013

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Article

SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein

Shou-Jen Kuo, Hui-Yi Lin, Su-Yu Chien, Dar-Ren Chen
Pages: 125-130
Published online on: 15 May 2013

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Article

Estrogen receptor-β expression and pharmacological targeting in bladder cancer

Eric C. Kauffman, Brian D. Robinson, Martin Downes, Katarzyna Marcinkiewicz, Srinivas Vourganti, Douglas S. Scherr, Lorraine J. Gudas, Nigel P. Mongan
Pages: 131-138
Published online on: 23 April 2013

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Article

Crizotinib may be used in lewis lung carcinoma: A novel use for crizotinib

Pu Xia, Wen-Feng Gou, Shuang Zhao, Hua-Chuan Zheng
Pages: 139-148
Published online on: 24 April 2013

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Article

Inhibition of pancreatic cancer and potentiation of gemcitabine effects by the extract of Pao Pereira

Jun Yu, Jeanne Drisko, Qi Chen
Pages: 149-156
Published online on: 14 May 2013

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Article

Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model

Xiang-Jun Ji, Sui-Hua Chen, Lin Zhu, Hao Pan, Yuan Zhou, Wei Li, Wan-Chun You, Chao-Chao Gao, Jian-Hong Zhu, Kuan Jiang, Han-Dong Wang
Pages: 157-164
Published online on: 15 May 2013

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Article

STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer

Jie Li, Geng Cui, Lu Sun, Shu-Juan Wang, Ya-Li Li, Yuan-Guang Meng, Zheng Guan, Wen-Sheng Fan, Li-An Li, Yi-Zhuo Yang, Yan-Qin You, Xiao-Yu Fu, Zhi-Feng Yan, Ke Huang
Pages: 165-170
Published online on: 22 April 2013

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Article

Knockdown of interferon-induced transmembrane protein 3 expression suppresses breast cancer cell growth and colony formation and affects the cell cycle

Mei Yang, Hongwen Gao, Peng Chen, Jiaoyuan Jia, Shan Wu
Pages: 171-178
Published online on: 26 April 2013

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Article

Specific reversal of tumor-suppressor gene promoter hypermethylation with bovine oocyte extract

Zhenfei Wang, Haixia Gao, Huimin Wang, Xiaolu Ren, Luri Bao, Rula Sa, Jie Wang, Haidong Bai, Haiquan Yu
Pages: 179-184
Published online on: 10 May 2013

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Article

Epigenetic silencing of Bcl-2, CEBPA and p14ARF by the AML1-ETO oncoprotein contributing to growth arrest and differentiation block in the U937 cell line

Wen-Yue Zhuang, Jian-Nong Cen, Yun Zhao, Zi-Xing Chen
Pages: 185-192
Published online on: 14 May 2013

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Article

Downregulation of BMP6 enhances cell proliferation and chemoresistance via activation of the ERK signaling pathway in breast cancer

Wen-Jing Lian, Geng Liu, Yuan-Jie Liu, Zhi-Wei Zhao, Tao Yi, Hong-Ying Zhou
Pages: 193-200
Published online on: 14 May 2013

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Article

OCT4 is epigenetically regulated by DNA hypomethylation of promoter and exon in primary gliomas

Jinlong Shi, Wei Shi, Lanchun Ni, Xide Xu, Xing Su, Liang Xia, Feng Xu, Jian Chen, Jianhong Zhu
Pages: 201-206
Published online on: 13 May 2013

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Article

Molecular characteristics of homologous salivary adenoid cystic carcinoma cell lines with different lung metastasis ability

Lin Wang, Yixiang Wang, Huan Bian, Yinfei Pu, Chuanbin Guo
Pages: 207-212
Published online on: 14 May 2013

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Article

Silencing of pancreatic adenocarcinoma upregulated factor by RNA interference inhibits the malignant phenotypes of human colorectal cancer cells

Peng-Fei Liu, Yun-Yun Wu, You Hu, Lei Wang, Song-Bing He, Yi-Bei Zhu, Xin-Guo Zhu
Pages: 213-220
Published online on: 15 May 2013

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Article

The in vitro antitumor activity of Siegesbeckia glabrescens against ovarian cancer through suppression of receptor tyrosine kinase expression and the signaling pathways

Young-Rak Cho, Shin Wook Choi, Dong-Wan Seo
Pages: 221-226
Published online on: 15 May 2013

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Article

Indole-3-carbinol inhibits cell proliferation and induces apoptosis in Hep-2 laryngeal cancer cells

Ya-Qiu Wang, Chen Chen, Zhe Chen, Yong Xu, Yan Wang, Bo-Kui Xiao, Shi-Ming Chen, Ze-Zhang Tao
Pages: 227-233
Published online on: 22 April 2013

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Article

Melanoma antigen gene family A as a molecular marker of gastric and colorectal cancers

Tae-Bum Lee, Sung-Chul Lim, Young-Sook Moon, Cheol-Hee Choi
Pages: 234-238
Published online on: 14 May 2013

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Article

A new curcumin analogue exhibits enhanced antitumor activity in nasopharyngeal carcinoma

Yunbao Pan, Jian Xiao, Guang Liang, Mengyao Wang, Dujuan Wang, Sumei Wang, Huiling Yang
Pages: 239-245
Published online on: 14 May 2013

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Article

Treatment of 131I-labeled anti-CD147 monoclonal antibody in VX2 carcinoma-induced liver tumors

Huanzhang Niu, Ruihua Wang, Jingliang Cheng, Shegan Gao, Baoping Liu
Pages: 246-252
Published online on: 23 April 2013

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Article

The role of CDK1 in apoptin-induced apoptosis in hepatocellular carcinoma cells

Jing Zhao, Su-Xia Han, Jin-Lu Ma, Xia Ying, Peijun Liu, Juan Li, Lijuan Wang, Ying Zhang, Jiguang Ma, Li Zhang, Qing Zhu
Pages: 253-259
Published online on: 25 April 2013

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Article

Expression of human full-length MUC1 inhibits the proliferation and migration of a B16 mouse melanoma cell line

Fengli Wang, Qiongshu Li, Weihua Ni, Fang Fang, Xiaxia Sun, Fei Xie, Juan Wang, Fang Wang, Sujun Gao, Guixiang Tai
Pages: 260-268
Published online on: 30 April 2013

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Article

Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells

Huawei Cai, Fangyu Peng
Pages: 269-275
Published online on: 29 April 2013

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Article

Diagnostic and biological significance of microRNA-192 in pancreatic ductal adenocarcinoma

Chenyan Zhao, Jing Zhang, Shuhui Zhang, Danghui Yu, Ying Chen, Qinghua Liu, Min Shi, Canrong Ni, Minghua Zhu
Pages: 276-284
Published online on: 23 April 2013

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Article

Differential expression of cell adhesion molecules in an ionizing radiation-induced breast cancer model system

Gloria M. Calaf, Debasish Roy, Gopeshwar Narayan, Adayabalam S. Balajee
Pages: 285-291
Published online on: 10 May 2013

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Article

Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways

Jian-Li Gao, Gui-Yuan Lv, Bai-Cheng He, Bing-Qiang Zhang, Hongyu Zhang, Ning Wang, Chong-Zhi Wang, Wei Du, Chun-Su Yuan, Tong-Chuan He
Pages: 292-298
Published online on: 30 April 2013

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Article

Spontaneous clearance of Helicobacter pylori after pylorus-preserving gastrectomy for gastric cancer

Tomoharu Miyashita, Koichi Miwa, Masafumi Inokuchi, Hisatoshi Nakagawara, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Takanori Hattori, Tetsuo Ohta
Pages: 299-303
Published online on: 15 May 2013

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Article

Raf kinase inhibitor protein inhibits esophageal cancer cell invasion through downregulation of matrix metalloproteinase expression

Dongqiang Zhao, Junji Ma, Junli Shi, Lijuan Cheng, Fangfang Li, Xiaoyu Jiang, Huiqing Jiang
Pages: 304-312
Published online on: 14 May 2013

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Article

Overexpression of Numb suppresses tumor cell growth and enhances sensitivity to cisplatin in epithelioid malignant pleural mesothelioma

Yanmeng Kang, Mingjie Ding, Guangyan Tian, Haisheng Guo, Yunyan Wan, Zhouhong Yao, Bin Li, Dianjie Lin
Pages: 313-319
Published online on: 26 April 2013

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Article

microRNA expression profile in stage III colorectal cancer: Circulating miR-18a and miR-29a as promising biomarkers

Anna Brunet Vega, Carles Pericay, Irene Moya, Anna Ferrer, Emma Dotor, Aleydis Pisa, Àlex Casalots, Xavier Serra-Aracil, Joan-Carles Oliva, Anna Ruiz, Eugeni Saigí
Pages: 320-326
Published online on: 15 May 2013

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Article

microRNA-330 inhibits cell motility by downregulating Sp1 in prostate cancer cells

Yeqing Mao, Hong Chen, Yiwei Lin, Xin Xu, Zhenghui Hu, Yi Zhu, Jian  Wu, Xianglai Xu, Xiangyi Zheng, Liping Xie
Pages: 327-333
Published online on: 13 May 2013

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Article

Search for mutations in signaling pathways in head and neck squamous cell carcinoma

Thais Gulim De Carvalho, Ana Carolina De Carvalho, Danielle Calheiros Campelo Maia, Juliana Kaori Ogawa, Andre Lopes Carvalho, Andre Luiz Vettore
Pages: 334-340
Published online on: 13 May 2013

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Article

Identification of integrin β1 as a prognostic biomarker for human lung adenocarcinoma using 2D-LC‑MS/MS combined with iTRAQ technology

Peng-Fei Zhang, Gu-Qing Zeng, Lun-Zhao Yi, Jian-Ping Liu, Xun‑Xun Wan, Jia-Quan Qu, Jian-Huang Li, Cui Li, Can-E Tang, Rong Hu, Xu Ye, Yu Chen, Zhu-Chu Chen, Zhi-Qiang Xiao
Pages: 341-349
Published online on: 15 May 2013

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Article

Magnifying narrow-band imaging of surface patterns for diagnosing colorectal cancer

Masashi Misawa, Shin-Ei Kudo, Yoshiki Wada, Hiroki Nakamura, Naoya Toyoshima, Seiko Hayashi, Yuichi Mori, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Fuyuhiko Yamamura, Shigeharu Hamatani
Pages: 350-356
Published online on: 15 May 2013

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Article

Quercetin synergizes with 2-methoxyestradiol inhibiting cell growth and inducing apoptosis in human prostate cancer cells

Guodong Wang, Liming Song, Huiping Wang, Nianzeng Xing
Pages: 357-363
Published online on: 15 May 2013

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Article

Downregulation of aryl hydrocarbon receptor expression decreases gastric cancer cell growth and invasion

Xiao-Fei Yin, Jie Chen, Wei Mao, Yu-Hong Wang, Min-Hu Chen
Pages: 364-370
Published online on: 22 April 2013

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Article

Human papillomavirus predicts the outcome following concomitant chemoradiotherapy in patients with head and neck squamous cell carcinomas

Anaëlle Duray, Géraldine Descamps, Christine Decaestecker, Nicolas Sirtaine, André Gilles, Mohamad Khalifé, Gilbert Chantrain, Christophe E. Depuydt, Philippe Delvenne, Sven Saussez
Pages: 371-376
Published online on: 22 April 2013

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Article

Inhibition of CK2 enhances UV-triggered apoptotic cell death in lung cancer cell lines

Tiesuo Zhao, Huijie Jia, Lifei Li, Guoliang Zhang, Min Zhao, Qian Cheng, Junnian Zheng, Di Li
Pages: 377-384
Published online on: 18 April 2013

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Article

Basic fibroblast growth factor upregulates survivin expression in hepatocellular carcinoma cells via a protein kinase B-dependent pathway

Bo Sun, Haiyan Xu, Gang Zhang, Yongbao Zhu, Hukui Sun, Guihua Hou
Pages: 385-390
Published online on: 15 May 2013

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Article

Intrathecal administration of cyclic AMP response element-binding protein-antisense oligonucleotide attenuates neuropathic pain after peripheral nerve injury and decreases the expression of N-Methyl-D-Aspartic receptors in mice

Xiaoping Gu, Jinhua Bo, Wei Zhang, Xiaofeng Sun, Juan Zhang, Yan Yang, Zhengliang Ma
Pages: 391-398
Published online on: 30 April 2013

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Article

miR-449b inhibits the proliferation of SW1116 colon cancer stem cells through downregulation of CCND1 and E2F3 expression

Yantian Fang, Xiaodong Gu, Zhengyang Li, Jianbin Xiang, Zongyou Chen
Pages: 399-406
Published online on: 14 May 2013

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Article

Human hsp70 and HPV16 oE7 fusion protein vaccine induces an effective antitumor efficacy

Jinbao Zong, Changyuan Wang, Bin Liu, Mingjun Liu, Yongxian Cao, Xiufang Sun, Yuan Yao, Guirong Sun
Pages: 407-412
Published online on: 09 May 2013

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Article

Combination of GHRH antagonists and docetaxel shows experimental effectiveness for the treatment of triple-negative breast cancers

S. Seitz, F. G. Rick, A. V. Schally, A. Treszl, F. Hohla, L. Szalontay, M. Zarandi, O. Ortmann, J. B. Engel, S. Buchholz
Pages: 413-418
Published online on: 29 April 2013

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Article

Extracellular signal-regulated kinase 2 mediates the expression of granulocyte colony-stimulating factor in invasive cancer cells

Chia-Huei Lee, Szu-Han Lin, Shwu-Fen Chang, Po-Yuan Chang, Zhi-Ping Yang, Shao-Chun Lu
Pages: 419-424
Published online on: 14 May 2013

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Article

4-Chlorobenzoyl berbamine, a novel berbamine derivative, induces apoptosis in multiple myeloma cells through the IL-6 signal transduction pathway and increases FOXO3a-Bim expression

Jia-Kun Shen, Hua-Ping Du, Qiuling Ma, Min Yang, Yun-Gui Wang, Jie Jin
Pages: 425-432
Published online on: 26 April 2013

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Enhanced autophagic flux by endoplasmic reticulum stress in human hepatocellular carcinoma cells contributes to the maintenance of cell viability

Tai Ma, Yuan-Yuan Li, Jie Zhu, Lu-Lu Fan, Wei-Dong Du, Chang-Hao Wu, Guo-Ping Sun, Jia-Bin Li
Pages: 433-440
Published online on: 15 May 2013

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Validity of bone marker measurements for monitoring response to bisphosphonate therapy with zoledronic acid in metastatic breast cancer

Bahriye Aktas, Sabine Kasimir-Bauer, Nils Lehmann, Rainer Kimmig, Mitra Tewes
Pages: 441-447
Published online on: 22 April 2013

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Article

NK4 regulates 5-fluorouracil sensitivity in cholangiocarcinoma cells by modulating the intrinsic apoptosis pathway

Xianxiu Ge, Youli Wang, Quanpeng Li, Hong Yu, Guozhong Ji, Lin Miao
Pages: 448-454
Published online on: 25 April 2013

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Association between lymphoma prognosis and aberrant methylation of ID4 and ZO-1 in bone marrow and paraffin-embedded lymphoma tissues of treatment-naive patients

Jian Cen, Jianliang Shen, Xinrong Wang, Huiyuan Kang, Lili Wang, Lu Sun, Yonghui Li, Li Yu
Pages: 455-461
Published online on: 10 May 2013

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Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells

Andreas Eisenreich, Andreas Zakrzewicz, Kilian Huber, Hannes Thierbach, Wojciech Pepke, Petra Goldin-Lang, Heinz-Peter Schultheiss, Axel Pries, Ursula Rauch
Pages: 462-470
Published online on: 22 April 2013

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Pre-activation of the p53 pathway through Nutlin-3a sensitises sarcomas to drozitumab therapy

Kathleen I. Pishas, Susan J. Neuhaus, Mark T. Clayer, Alaknanda Adwal, Michael P. Brown, Andreas Evdokiou, David F. Callen, Paul M. Neilsen
Pages: 471-477
Published online on: 13 May 2013

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Cytochalasin D promotes pulmonary metastasis of B16 melanoma through expression of tissue factor

Feng-Ying Huang, Wen-Li Mei, Guang-Hong Tan, Hao-Fu Dai, Yue-Nan Li, Jun-Li Guo, Yong-Hao Huang, Huan-Ge Zhao, Hua Wang, Song-Lin Zhou, Ying-Ying Lin
Pages: 478-484
Published online on: 24 April 2013

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Article

Low-dose 1,25-dihydroxyvitamin D3 combined with arsenic trioxide synergistically inhibits proliferation of acute myeloid leukemia cells by promoting apoptosis

Ji-Yeon Bae, Ji-Won Kim, Inho Kim
Pages: 485-491
Published online on: 09 May 2013

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Article

miR-150, p53 protein and relevant miRNAs consist of a regulatory network in NSCLC tumorigenesis

De-Tao Wang, Zhong-Liang Ma, Yan-Li Li, Yue-Qing Wang, Bo-Tao Zhao, Jia-Li Wei, Xiang Qi, Xin-Tai Zhao, You-Xin Jin
Pages: 492-498
Published online on: 13 May 2013

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Antitumor effects of a novel histone deacetylase inhibitor NK-HDAC-1 on breast cancer

Zhong-Hua Li, Xiao-Bing Zhang, Xi-Qian Han, Cong-Ran Feng, Feng‑Shan Wang, Peng George Wang, Jie Shen, Yi-Kang Shi
Pages: 499-505
Published online on: 29 April 2013

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Article

RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK

Ji Hoon Jang, Seon Min Woo, Hee Jung Um, Eun Jung Park, Kyoung-Jin Min, Tae-Jin Lee, Sang Hyun Kim, Yung Hyun Choi, Taeg Kyu Kwon
Pages: 506-512
Published online on: 26 April 2013

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Article

MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion

Woo Hyun Park, Suhn Hee Kim
Pages: 513-519
Published online on: 09 May 2013

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Article

miR-573 regulates melanoma progression by targeting the melanoma cell adhesion molecule

He-Fei Wang, Hong Chen, Min-Wang Ma, Ji-An Wang, Ting-Ting Tang, Lai-Sheng Ni, Jin-Ling Yu, Yu-Zhen Li, Bing-Xue Bai
Pages: 520-526
Published online on: 13 May 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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