Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
2014-January Volume 31 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
2014-January Volume 31 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies

  • Authors:
    • Xiaohui Xu
    • Xiaodong Yang
    • Gan Ru
    • Yong Wu
    • Shuyu Zhang
    • Chungen Xing
    • Yongyou Wu
    • Jianping Cao
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, The Second Affiliated Hospital of Soochow University, Suzhou 215004, P.R. China, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou 215123, P.R. China
  • Pages: 472-479
    |
    Published online on: November 15, 2013
       https://doi.org/10.3892/or.2013.2854
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Digestive tumors have the highest incidence among all tumor types worldwide. miR-146a has been shown to play an important role in the development, apoptosis, invasion and metastasis of digestive tumors. Additionally, a miR-146a gene polymorphism has been associated with the risk of a variety of cancer types in the digestive system. Therefore, in order to investigate the correlation, a meta-analysis of reported data was conducted, for which we obtained 21 research studies concerning the association between the miR-146a gene polymorphism and digestive tumors. Odds ratio (OR) values and 95% confidence intervals (95% CI) were used to assess this association. We found that the miR-146a polymorphism rs2910164 might significantly increase the susceptibility of digestive tumors, in particular for esophageal cancer and colorectal cancers. Furthermore, the miR-146a polymorphism might significantly increase the risk of digestive tumors in Asians. However, no obvious correlation between the polymorphism and the risk for digestive tumors was found in Caucasians.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Jemal A, Bray F, Center MM, et al: Global cancer statistics. CA Cancer J Clin. 61:69–90. 2011. View Article : Google Scholar

2 

Giovannucci E, Egan KM, Hunter DJ, et al: Aspirin and the risk of colorectal cancer in women. N Engl J Med. 333:609–614. 1995. View Article : Google Scholar : PubMed/NCBI

3 

Landi D, Moreno V, Guino E, et al: Polymorphisms affecting micro-RNA regulation and associated with the risk of dietary-related cancers: a review from the literature and new evidence for a functional role of rs17281995 (CD86) and rs1051690 (INSR), previously associated with colorectal cancer. Mutat Res. 717:109–115. 2011. View Article : Google Scholar : PubMed/NCBI

4 

Xu X, Yang X, Xing C, et al: miRNA: the nemesis of gastric cancer (Review). Oncol Lett. 6:631–641. 2013.PubMed/NCBI

5 

Hou Z, Xie L, Yu L, et al: MicroRNA-146a is down-regulated in gastric cancer and regulates cell proliferation and apoptosis. Med Oncol. 29:886–892. 2012. View Article : Google Scholar : PubMed/NCBI

6 

Vinci S, Gelmini S, Mancini I, et al: Genetic and epigenetic factors in regulation of microRNA in colorectal cancers. Methods. 59:138–146. 2013. View Article : Google Scholar : PubMed/NCBI

7 

He Y, Huang C, Sun X, et al: MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4. Cell Signal. 24:1923–1930. 2012. View Article : Google Scholar : PubMed/NCBI

8 

Tomokuni A, Eguchi H, Tomimaru Y, et al: miR-146a suppresses the sensitivity to interferon-α in hepatocellular carcinoma cells. Biochem Biophys Res Commun. 414:675–680. 2011.PubMed/NCBI

9 

Li Y, Vandenboom TG II, Wang Z, et al: miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res. 70:1486–1495. 2010. View Article : Google Scholar : PubMed/NCBI

10 

Wang X, Tang S, Le SY, et al: Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One. 3:e25572008. View Article : Google Scholar : PubMed/NCBI

11 

Yu J, Li A, Hong SM, et al: MicroRNA alterations of pancreatic intraepithelial neoplasias. Clin Cancer Res. 18:981–992. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Xu B, Wang N, Wang X, et al: MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. Prostate. 72:1171–1178. 2012. View Article : Google Scholar : PubMed/NCBI

13 

Lian H, Wang L and Zhang J: Increased risk of breast cancer associated with CC genotype of Hsa-miR-146a Rs2910164 polymorphism in Europeans. PLoS One. 7:e316152012. View Article : Google Scholar : PubMed/NCBI

14 

Yue C, Wang M, Ding B, et al: Polymorphism of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population. Gynecol Oncol. 122:33–37. 2011. View Article : Google Scholar : PubMed/NCBI

15 

Wang J, Bi J, Liu X, et al: Hsa-miR-146a polymorphism (rs2910164) and cancer risk: a meta-analysis of 19 case-control studies. Mol Biol Rep. 39:4571–4579. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Xu T, Zhu Y, Wei QK, et al: A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis. 29:2126–2131. 2008.PubMed/NCBI

17 

Ye Y, Wang KK, Gu J, et al: Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. Cancer Prev Res (Phila). 460–469. 2008. View Article : Google Scholar : PubMed/NCBI

18 

Srivastava K, Srivastava A and Mittal B: Common genetic variants in pre-microRNAs and risk of gallbladder cancer in North Indian population. J Hum Genet. 55:495–499. 2010. View Article : Google Scholar : PubMed/NCBI

19 

Guo H, Wang K, Xiong G, et al: A functional variant in microRNA-146a is associated with risk of esophageal squamous cell carcinoma in Chinese Han. Fam Cancer. 9:599–603. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Zeng Y, Sun QM, Liu NN, et al: Correlation between pre-miR-146a C/G polymorphism and gastric cancer risk in Chinese population. World J Gastroenterol. 16:3578–3583. 2010.PubMed/NCBI

21 

Min KT, Kim JW, Jeon YJ, et al: Association of the miR-146aC>G, 149C>T, 196a2C>T, and 499A>G polymorphisms with colorectal cancer in the Korean population. Mol Carcinog. 51(Suppl 1): E65–E73. 2012.

22 

Akkiz H, Bayram S, Bekar A, et al: No association of pre-microRNA-146a rs2910164 polymorphism and risk of hepatocellular carcinoma development in Turkish population: a case-control study. Gene. 486:104–109. 2011. View Article : Google Scholar : PubMed/NCBI

23 

Hishida A, Matsuo K, Goto Y, et al: Combined effect of miR-146a rs2910164 G/C polymorphism and Toll-like receptor 4 +3725 G/C polymorphism on the risk of severe gastric atrophy in Japanese. Dig Dis Sci. 56:1131–1137. 2011.

24 

Okubo M, Tahara T, Shibata T, et al: Association between common genetic variants in pre-microRNAs and gastric cancer risk in Japanese population. Helicobacter. 15:524–531. 2010. View Article : Google Scholar : PubMed/NCBI

25 

Zhang XW, Pan SD, Feng YL, et al: Relationship between genetic polymorphism in microRNAs precursor and genetic predisposition of hepatocellular carcinoma. Zhonghua Yu Fang Yi Xue Za Zhi. 45:239–243. 2011.(In Chinese).

26 

Xiang Y, Fan S, Cao J, et al: Association of the microRNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population. Mol Biol Rep. 39:7019–7023. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Kim WH, Min KT, Jeon YJ, et al: Association study of microRNA polymorphisms with hepatocellular carcinoma in Korean population. Gene. 504:92–97. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Zhou F, Zhu H, Luo D, et al: A functional polymorphism in Pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population. DNA Cell Biol. 31:1290–1295. 2012.PubMed/NCBI

29 

Ahn DH, Rah H, Choi YK, et al: Association of the miR-146a C>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with gastric cancer risk and survival in the Korean population. Mol Carcinog. 52(Suppl 1): 39–51. 2013.

30 

Hezova R, Kovarikova A, Bienertova-Vasku J, et al: Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer. World J Gastroenterol. 18:2827–2831. 2012. View Article : Google Scholar : PubMed/NCBI

31 

Mihalache F, Hoblinger A, Acalovschi M, et al: A common variant in the precursor miR-146a sequence does not predispose to cholangiocarcinoma in a large European cohort. Hepatob Pancreat Dis Int. 11:412–417. 2012. View Article : Google Scholar : PubMed/NCBI

32 

Zhou J, Lv R, Song X, et al: Association between two genetic variants in miRNA and primary liver cancer risk in the Chinese population. DNA Cell Biol. 31:524–530. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Song MY, Su HJ, Zhang L, et al: Genetic polymorphisms of miR-146a and miR-27a, H. pylori infection, and risk of gastric lesions in a Chinese population. PLoS One. 8:e612502013.PubMed/NCBI

34 

Ma L, Zhu L, Gu D, et al: A genetic variant in miR-146a modifies colorectal cancer susceptibility in a Chinese population. Arch Toxicol. 87:825–833. 2013. View Article : Google Scholar : PubMed/NCBI

35 

Lv M, Dong W, Li L, et al: Association between genetic variants in pre-miRNA and colorectal cancer risk in a Chinese population. J Cancer Res Clin Oncol. 139:1405–1410. 2013. View Article : Google Scholar : PubMed/NCBI

36 

Pavlakis E, Papaconstantinou I, Gazouli M, et al: MicroRNA gene polymorphisms in pancreatic cancer. Pancreatology. 13:273–278. 2013. View Article : Google Scholar : PubMed/NCBI

37 

Yuan Z, Zeng X, Yang D, et al: Effects of common polymorphism rs11614913 in Hsa-miR-196a2 on lung cancer risk. PLoS One. 8:e610472013. View Article : Google Scholar : PubMed/NCBI

38 

Liu J, Liu J, He Y, et al: Genetic variants in the microRNA machinery gene GEMIN4 are associated with risk of prostate cancer: a case-control study of the Chinese Han population. DNA Cell Biol. 31:1296–1302. 2012.PubMed/NCBI

39 

Luo J, Cai Q, Wang W, et al: A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer. PLoS One. 7:e401272012. View Article : Google Scholar : PubMed/NCBI

40 

Zhou B, Wang K, Wang Y, et al: Common genetic polymorphisms in pre-microRNAs and risk of cervical squamous cell carcinoma. Mol Carcinog. 50:499–505. 2011. View Article : Google Scholar : PubMed/NCBI

41 

Löfgren SE, Frostegård J, Truedsson L, et al: Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene. Genes Immun. 13:268–274. 2012.PubMed/NCBI

42 

Zilahi E, Tarr T, Papp G, et al: Increased microRNA-146a/b, TRAF6 gene and decreased IRAK1 gene expressions in the peripheral mononuclear cells of patients with Sjögren’s syndrome. Immunol Lett. 141:165–168. 2012.PubMed/NCBI

43 

Lu J, Kwan BC, Lai FM, et al: Glomerular and tubulointerstitial miR-638, miR-198 and miR-146a expression in lupus nephritis. Nephrology. 17:346–351. 2012. View Article : Google Scholar : PubMed/NCBI

44 

Halkein J, Tabruyn SP, Ricke-Hoch M, et al: MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy. J Clin Invest. 123:2143–2154. 2013. View Article : Google Scholar : PubMed/NCBI

45 

Fan KL, Zhang HF, Shen J, et al: Circulating microRNAs levels in Chinese heart failure patients caused by dilated cardiomyopathy. Indian Heart J. 65:12–16. 2013. View Article : Google Scholar : PubMed/NCBI

46 

Zidar N, Boštjančič E, Glavač D and Stajer D: MicroRNAs, innate immunity and ventricular rupture in human myocardial infarction. Dis Markers. 31:259–265. 2011. View Article : Google Scholar : PubMed/NCBI

47 

Jazdzewski K, Murray EL, Franssila K, et al: Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci USA. 105:7269–7274. 2008.

48 

Yamashita J, Iwakiri T, Fukushima S, et al: The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma. Melanoma Res. 23:13–20. 2013.

49 

Orsós Z, Szanyi I, Csejtei A, et al: Association of pre-miR-146a rs2910164 polymorphism with the risk of head and neck cancer. Anticancer Res. 33:341–346. 2013.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Xu X, Yang X, Ru G, Wu Y, Zhang S, Xing C, Wu Y and Cao J: miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies. Oncol Rep 31: 472-479, 2014.
APA
Xu, X., Yang, X., Ru, G., Wu, Y., Zhang, S., Xing, C. ... Cao, J. (2014). miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies. Oncology Reports, 31, 472-479. https://doi.org/10.3892/or.2013.2854
MLA
Xu, X., Yang, X., Ru, G., Wu, Y., Zhang, S., Xing, C., Wu, Y., Cao, J."miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies". Oncology Reports 31.1 (2014): 472-479.
Chicago
Xu, X., Yang, X., Ru, G., Wu, Y., Zhang, S., Xing, C., Wu, Y., Cao, J."miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies". Oncology Reports 31, no. 1 (2014): 472-479. https://doi.org/10.3892/or.2013.2854
Copy and paste a formatted citation
x
Spandidos Publications style
Xu X, Yang X, Ru G, Wu Y, Zhang S, Xing C, Wu Y and Cao J: miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies. Oncol Rep 31: 472-479, 2014.
APA
Xu, X., Yang, X., Ru, G., Wu, Y., Zhang, S., Xing, C. ... Cao, J. (2014). miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies. Oncology Reports, 31, 472-479. https://doi.org/10.3892/or.2013.2854
MLA
Xu, X., Yang, X., Ru, G., Wu, Y., Zhang, S., Xing, C., Wu, Y., Cao, J."miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies". Oncology Reports 31.1 (2014): 472-479.
Chicago
Xu, X., Yang, X., Ru, G., Wu, Y., Zhang, S., Xing, C., Wu, Y., Cao, J."miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies". Oncology Reports 31, no. 1 (2014): 472-479. https://doi.org/10.3892/or.2013.2854
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team