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Article

Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival

  • Authors:
    • Anna Skalniak
    • Elżbieta Boratyn
    • Sylwia D. Tyrkalska
    • Irena Horwacik
    • Małgorzata Durbas
    • Maria Łastowska
    • Jolanta Jura
    • Hanna Rokita
  • View Affiliations / Copyright

    Affiliations: Laboratory of Molecular Genetics and Virology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Kraków, Poland, Department of Pathology, Institute ‘Pomnik‑Centrum Zdrowia Dziecka’, 04-730 Warsaw, Poland, Department of General Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Kraków, Poland
  • Pages: 2385-2392
    |
    Published online on: March 11, 2014
       https://doi.org/10.3892/or.2014.3076
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Abstract

The importance of monocyte chemotactic protein-1-induced protein 1 (MCPIP1) in the negative regulation of inflammatory reactions has already been extensively studied. However, its role in cancer is not yet established. We studied MCPIP1 gene expression in primary human neuroblastomas and several neuroblastoma cell lines. Our results showed a lack of MCPIP1 expression in primary neuroblastoma tumors. Moreover, it was found that the low expression of the protein measured in human neuroblastoma cell lines might be important for neuroblastoma survival, since enforced MCPIP1 gene expression in human neuroblastoma BE(2)-C cells caused a significant decrease in neuroblastoma cell viability and proliferation.
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1 

Zhou L, Azfer A, Niu J, Graham S, Choudhury M, Adamski FM, Younce C, Binkley PF and Kolattukudy PE: Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ Res. 98:1177–1185. 2006. View Article : Google Scholar

2 

Vrotsos EG, Kalattukudy PE and Sugaya K: MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling. Brain Res Bull. 79:97–103. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H and Akira S: Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature. 458:1185–1190. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Mizgalska D, Wegrzyn P, Murzyn K, Kasza A, Koj A and Jura J, Jarząb B and Jura J: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase participating in degradation of IL-1β mRNA. FEBS J. 276:7386–7399. 2009.PubMed/NCBI

5 

Liang J, Saad Y, Lei T, Wang J, Qi D, Yang Q, Kolattukudy PE and Fu M: MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling. J Exp Med. 207:2959–2973. 2010.PubMed/NCBI

6 

Jura J, Węgrzyn P, Korostyński M, Guzik K, Oczko-Wojciechowska M, Jarząb M, Kowalska M, Piechota M, Przewłocki R and Koj A: Identification of interleukin-1 and interleukin-6-responsive genes in human monocyte-derived macrophages using microarrays. Biochim Biophys Acta. 1799:383–389. 2008. View Article : Google Scholar : PubMed/NCBI

7 

Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE and Fu M: A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages. J Biol Chem. 283:6337–6346. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Jura J, Skalniak Ł and Koj A: Monocyte-chemotactic protein-1-induced protein-1 (MCPIP1) is a novel multifunctional modulator of inflammatory reactions. Biochim Biophys Acta. 1823:1905–1913. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Lin RJ, Chien HL, Lin SY, Chang BL, Yu HP, Tang WC and Lin YL: MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation. Nucleic Acids Res. 41:3314–3326. 2013. View Article : Google Scholar : PubMed/NCBI

10 

Skalniak L, Koj A and Jura J: Proteasome inhibitor MG-132 induces MCPIP1 expression. FEBS J. 280:2665–2674. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Suzuki HI, Arase M, Matsuyama H, Choi YL, Ueno T, Mano H, Sugimoto K and Miyazono K: MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell. 44:424–436. 2011. View Article : Google Scholar

12 

Garzon R, Calin GA and Croce CM: MicroRNAs in cancer. Annu Rev Med. 60:167–170. 2009. View Article : Google Scholar

13 

Deshmane SL, Kremlev S, Amini S and Sawaya BE: Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res. 29:313–326. 2009. View Article : Google Scholar : PubMed/NCBI

14 

Muramatsu T and Muramatsu H: Glycosaminoglycan-binding cytokines as tumor markers. Proteomics. 8:3350–3359. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Łastowska M, Viprey V, Santibanez-Koref M, Wappler I, Peters H, Cullinane C, Roberts P, Hall AG, Tweddle DA, Pearson ADJ, Lewis I, Burchill SA and Jackson MS: Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data. Oncogene. 26:7432–7444. 2007.PubMed/NCBI

16 

Kool M, Koster J, Bunt J, Hasselt NE, Lakeman A, van Sluis P, Troost D, Meeteren NS, Caron HN, Cloos J, Mrsić A, Ylstra B, Grajkowska W, Hartmann W, Pietsch T, Ellison D, Clifford SC and Versteeg R: Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One. 3:e30882008. View Article : Google Scholar : PubMed/NCBI

17 

Paugh BS, Qu C, Jones C, Liu Z, Adamowicz-Brice M, Zhang J, Bax DA, Coyle B, Barrow J, Hargrave D, Lowe J, Gajjar A, Zhao W, Broniscer A, Ellison DW, Grundy RG and Baker SJ: Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol. 28:3061–3068. 2010. View Article : Google Scholar : PubMed/NCBI

18 

Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB, Rand V, Leary SE, White E, Eden C, Hogg T, Northcott P, Mack S, Neale G, Wang YD, Coyle B, Atkinson J, DeWire M, Kranenburg TA, Gillespie Y, Allen JC, Merchant T, Boop FA, Sanford RA, Gajjar A, Ellison DW, Taylor MD, Grundy RG and Gilbertson RJ: Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature. 466:632–636. 2010. View Article : Google Scholar : PubMed/NCBI

19 

Bogenmann E: A metastatic neuroblastoma model in SCID mice. Int J Cancer. 67:379–385. 1996. View Article : Google Scholar : PubMed/NCBI

20 

Gauthier ER, Madison SD and Michel RN: Rapid RNA isolation without the use of commercial kits: application to small tissue samples. Eur J Physiol. 433:664–668. 1997. View Article : Google Scholar : PubMed/NCBI

21 

Smith PK: Measurement of protein using bicinchoninic acid. Anal Biochem. 150:76–85. 1985. View Article : Google Scholar

22 

Pomerantz JL and Baltimore D: Two pathways to NF-κB. Mol Cell. 10:693–695. 2002.

23 

Ueda A, Ishigatsubo Y, Okubo T and Yoshimura T: Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-κB sites and NF-κB/Rel subunit specificity. J Biol Chem. 272:31092–31099. 1997.PubMed/NCBI

24 

Skalniak L, Mizgalska D, Zarebski A, Wyrzykowska P, Koj A and Jura J: Regulatory feedback loop between NF-κB and MCP-1-induced protein 1 RNase. FEBS J. 276:5892–5905. 2009.

25 

Brodeur GM: Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer. 3:203–216. 2003. View Article : Google Scholar : PubMed/NCBI

26 

Maris JM, Hogarty MD, Bagatell R and Cohn SL: Neuroblastoma. Lancet. 369:2106–2120. 2007. View Article : Google Scholar : PubMed/NCBI

27 

Ora I and Eggert A: Progress in treatment and risk stratification of neuroblastoma: Impact on future clinical and basic research. Semin Cancer Biol. 21:217–228. 2011. View Article : Google Scholar : PubMed/NCBI

28 

Metelitsa LS, Wu HW, Wang H, Yang Y, Warsi Z, Asgharzadeh S, Groshen S, Wilson SB and Seeger RC: Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2. J Exp Med. 199:1213–1221. 2004. View Article : Google Scholar : PubMed/NCBI

29 

Song L, Ara T, Wu HW, Woo CW, Reynolds CP, Seeger RC, DeClerck YA, Thiele CJ, Sposto R and Metelitsa LS: Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma. J Clin Invest. 117:2702–2712. 2007. View Article : Google Scholar : PubMed/NCBI

30 

Iwasaki H, Takeuchi O, Teraguchi S, Matsushita K, Uehata T, Kuniyoshi K, Satoh T, Saitoh T, Matsuhita M, Standley DM and Akira S: The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1. Nat Immunol. 12:1167–1175. 2011.

31 

Chen Y and Stallings RL: Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation and apoptosis. Cancer Res. 67:976–983. 2007. View Article : Google Scholar : PubMed/NCBI

32 

Xu J, Fu S, Peng W and Rao Z: MCP-1-induced protein-1, an immune regulator. Protein Cell. 3:903–910. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Clissold PM and Ponting CP: PIN domain in nonsense-mediated mRNA decay and RNAi. Curr Biol. 10:R888–R890. 2000. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Skalniak A, Boratyn E, Tyrkalska SD, Horwacik I, Durbas M, Łastowska M, Jura J and Rokita H: Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival. Oncol Rep 31: 2385-2392, 2014.
APA
Skalniak, A., Boratyn, E., Tyrkalska, S.D., Horwacik, I., Durbas, M., Łastowska, M. ... Rokita, H. (2014). Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival. Oncology Reports, 31, 2385-2392. https://doi.org/10.3892/or.2014.3076
MLA
Skalniak, A., Boratyn, E., Tyrkalska, S. D., Horwacik, I., Durbas, M., Łastowska, M., Jura, J., Rokita, H."Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival". Oncology Reports 31.5 (2014): 2385-2392.
Chicago
Skalniak, A., Boratyn, E., Tyrkalska, S. D., Horwacik, I., Durbas, M., Łastowska, M., Jura, J., Rokita, H."Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival". Oncology Reports 31, no. 5 (2014): 2385-2392. https://doi.org/10.3892/or.2014.3076
Copy and paste a formatted citation
x
Spandidos Publications style
Skalniak A, Boratyn E, Tyrkalska SD, Horwacik I, Durbas M, Łastowska M, Jura J and Rokita H: Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival. Oncol Rep 31: 2385-2392, 2014.
APA
Skalniak, A., Boratyn, E., Tyrkalska, S.D., Horwacik, I., Durbas, M., Łastowska, M. ... Rokita, H. (2014). Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival. Oncology Reports, 31, 2385-2392. https://doi.org/10.3892/or.2014.3076
MLA
Skalniak, A., Boratyn, E., Tyrkalska, S. D., Horwacik, I., Durbas, M., Łastowska, M., Jura, J., Rokita, H."Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival". Oncology Reports 31.5 (2014): 2385-2392.
Chicago
Skalniak, A., Boratyn, E., Tyrkalska, S. D., Horwacik, I., Durbas, M., Łastowska, M., Jura, J., Rokita, H."Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival". Oncology Reports 31, no. 5 (2014): 2385-2392. https://doi.org/10.3892/or.2014.3076
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