Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer

  • Authors:
    • Roberto Berretta
    • Tito Silvio Patrelli
    • Costanza Migliavacca
    • Martino Rolla
    • Laura Franchi
    • Michela Monica
    • Alberto Bacchi Modena
    • Salvatore Gizzo
  • View Affiliations

  • Published online on: March 21, 2014     https://doi.org/10.3892/or.2014.3108
  • Pages: 2407-2412
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Abstract

Accumulating evidence suggests that the estimation of tumor size may improve endometrial cancer treatment. We conducted an observational study aimed at elucidating the association between tumor size and other universally accepted prognostic factors in order to identify suitable preoperative parameters which can guide surgery in a subgroup of early corpus endometrial cancer. We found that when tumor size increased, both stage and grading were significantly increased. Tumor size was correlated with CA 125 serum values, node metastasis and peritoneal cytology status. Patients who have grade 1 or 2 endometrioid corpus cancer, myometrial invasion <50% and ≤3 cm largest tumor diameter can only be treated with hysterectomy. The tumor largest diameter should be evaluated as a preoperative parameter that indicates patients who do not require lymphadenectomy.
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May-2014
Volume 31 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Berretta R, Patrelli TS, Migliavacca C, Rolla M, Franchi L, Monica M, Modena AB and Gizzo S: Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer. Oncol Rep 31: 2407-2412, 2014
APA
Berretta, R., Patrelli, T.S., Migliavacca, C., Rolla, M., Franchi, L., Monica, M. ... Gizzo, S. (2014). Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer. Oncology Reports, 31, 2407-2412. https://doi.org/10.3892/or.2014.3108
MLA
Berretta, R., Patrelli, T. S., Migliavacca, C., Rolla, M., Franchi, L., Monica, M., Modena, A. B., Gizzo, S."Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer". Oncology Reports 31.5 (2014): 2407-2412.
Chicago
Berretta, R., Patrelli, T. S., Migliavacca, C., Rolla, M., Franchi, L., Monica, M., Modena, A. B., Gizzo, S."Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer". Oncology Reports 31, no. 5 (2014): 2407-2412. https://doi.org/10.3892/or.2014.3108