|
1
|
van Meerbeeck JP, Fennell DA and De
Ruysscher DK: Small-cell lung cancer. Lancet. 378:1741–1755.
2011.
|
|
2
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2012. CA Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar
|
|
3
|
Lally BE, Urbanic JJ, Blackstock AW,
Miller AA and Perry MC: Small cell lung cancer: have we made any
progress over the last 25 years? Oncologist. 12:1096–1104.
2007.PubMed/NCBI
|
|
4
|
Oze I, Hotta K, Kiura K, et al:
Twenty-seven years of phase III trials for patients with extensive
disease small-cell lung cancer: disappointing results. PLoS One.
4:e78352009.PubMed/NCBI
|
|
5
|
Vader G and Lens SM: The Aurora kinase
family in cell division and cancer. Biochim Biophys Acta.
1786:60–72. 2008.PubMed/NCBI
|
|
6
|
Nikonova AS, Astsaturov I, Serebriiskii
IG, Dunbrack RL Jr and Golemis EA: Aurora A kinase (AURKA) in
normal and pathological cell division. Cell Mol Life Sci.
70:661–687. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Katayama H, Brinkley WR and Sen S: The
Aurora kinases: role in cell transformation and tumorigenesis.
Cancer Metastasis Rev. 22:451–464. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Jiang Y, Zhang Y, Lees E and Seghezzi W:
AuroraA overexpression overrides the mitotic spindle checkpoint
triggered by nocodazole, a microtubule destabilizer. Oncogene.
22:8293–8301. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Anand S, Penrhyn-Lowe S and Venkitaraman
AR: AURORA-A amplification overrides the mitotic spindle
assembly checkpoint, inducing resistance to Taxol. Cancer Cell.
3:51–62. 2003. View Article : Google Scholar
|
|
10
|
Zhou H, Kuang J, Zhong L, et al: Tumour
amplified kinase STK15/BTAK induces centrosome amplification,
aneuploidy and transformation. Nat Genet. 20:189–193. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wang X, Zhou YX, Qiao W, et al:
Overexpression of aurora kinase A in mouse mammary epithelium
induces genetic instability preceding mammary tumor formation.
Oncogene. 25:7148–7158. 2006. View Article : Google Scholar
|
|
12
|
Burnett JC and Rossi JJ: RNA-based
therapeutics: current progress and future prospects. Chem Biol.
19:60–71. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Watts JK and Corey DR: Silencing disease
genes in the laboratory and the clinic. J Pathol. 226:365–379.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Castanotto D and Rossi JJ: The promises
and pitfalls of RNA-interference-based therapeutics. Nature.
457:426–433. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ketting RF: The many faces of RNAi. Dev
Cell. 20:148–161. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Stovold R, Blackhall F, Meredith S, Hou J,
Dive C and White A: Biomarkers for small cell lung cancer:
neuroendocrine, epithelial and circulating tumour cells. Lung
Cancer. 76:263–268. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Bischoff JR, Anderson L, Zhu Y, et al: A
homologue of Drosophila aurora kinase is oncogenic and
amplified in human cancers. EMBO J. 17:3052–3065. 1998.PubMed/NCBI
|
|
18
|
Reiter R, Gais P, Jütting U, et al: Aurora
kinase A messenger RNA overexpression is correlated with tumor
progression and shortened survival in head and neck squamous cell
carcinoma. Clin Cancer Res. 12:5136–5141. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lassus H, Staff S, Leminen A, Isola J and
Butzow R: Aurora-A overexpression and aneuploidy predict poor
outcome in serous ovarian carcinoma. Gynecol Oncol. 120:11–17.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Stein EV, Price DK and Figg WD: shRNA
technology: investigating Ras-dependent cancer. Cancer Biol Ther.
8:1798–1799. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Luo J, Emanuele MJ, Li D, et al: A
genome-wide RNAi screen identifies multiple synthetic lethal
interactions with the Ras oncogene. Cell. 137:835–848. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Brummelkamp TR, Bernards R and Agami R: A
system for stable expression of short interfering RNAs in mammalian
cells. Science. 296:550–553. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wang X, Dong L, Xie J, Tong T and Zhan Q:
Stable knockdown of Aurora-A by vector-based RNA interference in
human esophageal squamous cell carcinoma cell line inhibits tumor
cell proliferation, invasion and enhances apoptosis. Cancer Biol
Ther. 8:1852–1859. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wang X, Lu N, Niu B, Chen X, Xie J and
Cheng N: Overexpression of Aurora-A enhances invasion and matrix
metalloproteinase-2 expression in esophageal squamous cell
carcinoma cells. Mol Cancer Res. 10:588–596. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Yang G, Chang B, Yang F, et al: Aurora
kinase A promotes ovarian tumorigenesis through dysregulation of
the cell cycle and suppression of BRCA2. Clin Cancer Res.
16:3171–3181. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Satyanarayana A and Kaldis P: Mammalian
cell-cycle regulation: several Cdks, numerous cyclins and diverse
compensatory mechanisms. Oncogene. 28:2925–2939. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Riabowol K, Draetta G, Brizuela L, Vandre
D and Beach D: The cdc2 kinase is a nuclear protein that is
essential for mitosis in mammalian cells. Cell. 57:393–401. 1989.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Dutertre S, Cazales M, Quaranta M, et al:
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes
to the G2-M transition. J Cell Sci. 117:2523–2531. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Kelly PN and Strasser A: The role of Bcl-2
and its pro-survival relatives in tumourigenesis and cancer
therapy. Cell Death Differ. 18:1414–1424. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Qi F, Inagaki Y, Gao B, et al: Bufalin and
cinobufagin induce apoptosis of human hepatocellular carcinoma
cells via Fas- and mitochondria-mediated pathways. Cancer Sci.
102:951–958. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Oltersdorf T, Elmore SW, Shoemaker AR, et
al: An inhibitor of Bcl-2 family proteins induces regression of
solid tumours. Nature. 435:677–681. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Gu X, Yao Y, Cheng R, et al: Plasminogen
K5 activates mitochondrial apoptosis pathway in endothelial cells
by regulating Bak and Bcl-xL subcellular distribution.
Apoptosis. 16:846–855. 2011. View Article : Google Scholar : PubMed/NCBI
|
