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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2014 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (Review)

Rubí Viedma-Rodríguez, Luis Baiza-Gutman, Fabio Salamanca‑Gómez, Mariana Diaz‑Zaragoza, Guadalupe Martínez-Hernández, Ruth Ruiz Esparza‑Garrido, Miguel Angel Velázquez-Flores, Diego Arenas-Aranda
Pages: 3-15
Published online on: 16 May 2014

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Article Open Access

Timing of cisplatin administration for chemoradiotherapy in transgenic mice bearing lens tumors

Shoji Kaku, Norichika Ushioda, Hiroshi Ishii, Takashi Murakami, Kentaro Takahashi, Yuichiro Nakai, Koichiro Shimoya, Takafumi Nakamura
Pages: 16-22
Published online on: 20 May 2014

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Article Open Access

Galectin fingerprinting in naso-sinusal diseases

Anaëlle Duray, Thibault De Maesschalck, Christine Decaestecker, Myriam Remmelink, Gilbert Chantrain, Jennifer Neiveyans, Mihaela Horoi, Xavier Leroy, Hans-Joachim Gabius, Sven Saussez
Pages: 23-32
Published online on: 23 May 2014

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Article Open Access

Identification of a novel HLA-A*02:01-restricted cytotoxic T lymphocyte epitope derived from the EML4-ALK fusion gene

Mayuko Yoshimura, Yoshitaka Tada, Kazuya Ofuzi, Masakazu Yamamoto, Tetsuya Nakatsura
Pages: 33-39
Published online on: 19 May 2014

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Article Open Access

Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma

Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Kjetil Boye, Sverre Heim
Pages: 40-44
Published online on: 15 May 2014

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Article Open Access

Role of c-Src activity in the regulation of gastric cancer cell migration

Yun Yang, Zhi-Gang Bai, Jie Yin, Guo-Cong Wu, Zhong-Tao Zhang
Pages: 45-49
Published online on: 15 May 2014

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Article

Clinicopathological characteristics and prognostic impact of colorectal cancers with NRAS mutations

Toshiro Ogura, Miho Kakuta, Toshimasa Yatsuoka, Yoji Nishimura, Hirohiko Sakamoto, Kensei Yamaguchi, Minoru Tanabe, Yoichi Tanaka, Kiwamu Akagi
Pages: 50-56
Published online on: 06 May 2014

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Article

Impact of genetic profiles on the efficacy of anti-EGFR antibodies in metastatic colorectal cancer with KRAS mutation

Tomokazu Kishiki, Hiroaki Ohnishi, Tadahiko Masaki, Kouki Ohtsuka, Yasuo Ohkura, Jyunji Furuse, Masanori Sugiyama, Takashi Watanabe
Pages: 57-64
Published online on: 15 May 2014

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Article

Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells

Koichi Shoji, Jun Teishima, Tetsutaro Hayashi, Shinya Ohara, Wallace L. Mckeehan, Akio Matsubara
Pages: 65-70
Published online on: 20 May 2014

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Article

Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways

Eun Jeong Gweon, Song-Ja Kim
Pages: 71-78
Published online on: 16 May 2014

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Article

Inhibitor of DNA-binding protein 1 knockdown arrests the growth of colorectal cancer cells and suppresses hepatic metastasis in vivo

Xiaolan Lai, Jinrong Liao, Wansong Lin, Chuanzhong Huang, Jieyu Li, Jizhen Lin, Qiang Chen, Yunbin Ye
Pages: 79-88
Published online on: 08 May 2014

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Article

Comparative study of the antitumor activity of Nab-paclitaxel and intraperitoneal solvent-based paclitaxel regarding peritoneal metastasis in gastric cancer

Jun Kinoshita, Sachio Fushida, Tomoya Tsukada, Katsunobu Oyama, Toshihumi Watanabe, Masatoshi Shoji, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Hiroyuki Furukawa, Hironori Hayashi, Keishi Nakamura, Masahumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Takashi Fujimura, Yashiro Masakazu, Kosei Hirakawa, Tetsuo Ohta
Pages: 89-96
Published online on: 23 May 2014

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Article

Global fecal microRNA profiling in the identification of biomarkers for colorectal cancer screening among Asians

Lee Cheng Phua, Xiu Ping Chue, Poh Koon Koh, Peh Yean Cheah, Eric Chun Yong Chan, Han Kiat Ho
Pages: 97-104
Published online on: 16 May 2014

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Article

Gastric cancer cell adhesion to laminin enhances acquired chemotherapeutic drug resistance mediated by MGr1-Ag/37LRP

Li Sun, Lili Liu, Xiangqiang Liu, Yafang Wang, Mengbin Li, Liping Yao, Jianjun Yang, Genlin Ji, Changcun Guo, Yanglin Pan, Shuhui Liang, Biaoluo Wang, Jie Ding, Hongwei Zhang, Yongquan Shi
Pages: 105-114
Published online on: 15 May 2014

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Article

MicroRNA-223 functions as an oncogene in human colorectal cancer cells

Jufeng Zhang, Xia Luo, Huiming Li, Xupeng Yue, Lin Deng, Yuanyuan Cui, Yanxin Lu
Pages: 115-120
Published online on: 08 May 2014

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Article

MMP-2/9-oriented combinations enhance antitumor efficacy of EGFR/HER2-targeting fusion proteins and gemcitabine

Ye Qin, Xiu-Jun Liu, Liang Li, Xu-Jie Liu, Yi Li, Rui‑Juan Gao, Rong-Guang Shao, Yong-Su Zhen
Pages: 121-130
Published online on: 07 May 2014

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Article

2'-Hydroxyflavanone inhibits prostate tumor growth through inactivation of AKT/STAT3 signaling and induction of cell apoptosis

Kaijie Wu, Zhongyun Ning, Jiancheng Zhou, Bin Wang, Jinhai Fan, Jianning Zhu, Yang Gao, Xinyang Wang, Jer-Tsong Hsieh, Dalin He
Pages: 131-138
Published online on: 26 May 2014

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Article

Interaction of ribosomal protein L22 with casein kinase 2α: A novel mechanism for understanding the biology of non-small cell lung cancer

Mingxia Yang, Haibo Sun, Ji He, Hong Wang, Xiaowei Yu, Lei Ma, Changliang Zhu
Pages: 139-144
Published online on: 15 May 2014

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Article

Presence of the minor EGFR T790M mutation is associated with drug-sensitive EGFR mutations in lung adenocarcinoma patients

Shinsuke Hashida, Junichi Soh, Shinichi Toyooka, Tomoaki Tanaka, Masashi Furukawa, Kazuhiko Shien, Hiromasa Yamamoto, Hiroaki Asano, Kazunori Tsukuda, Koichi Hagiwara, Shinichiro Miyoshi
Pages: 145-152
Published online on: 16 May 2014

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Article

Establishment of hypoxia induction in an in vivo animal replacement model for experimental evaluation of pancreatic cancer Corrigendum in /10.3892/or.2023.8626

Nathalie Bauer, Li Liu, Ewa Aleksandrowicz, Ingrid Herr
Pages: 153-158
Published online on: 16 May 2014

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Article

YKL-40 downregulation is a key factor to overcome temozolomide resistance in a glioblastoma cell line

Yasuto Akiyama, Tadashi Ashizawa, Masaru Komiyama, Haruo Miyata, Chie Oshita, Maho Omiya, Akira Iizuka, Akiko Kume, Takashi Sugino, Nakamasa Hayashi, Koichi Mitsuya, Yoko Nakasu, Ken Yamaguchi
Pages: 159-166
Published online on: 16 May 2014

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Article

The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells

Daniela Carlisi, Antonella D'Anneo, Roberta Martinez, Sonia Emanuele, Giuseppina Buttitta, Riccardo Di Fiore, Renza Vento, Giovanni Tesoriere, Marianna Lauricella
Pages: 167-172
Published online on: 23 May 2014

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Article

Curcumin suppresses cell proliferation through inhibition of the Wnt/β-catenin signaling pathway in medulloblastoma

Misi He, Yu Li, Li Zhang, Longjiang Li, Yi Shen, Ling Lin, Weiping Zheng, Li Chen, Xiuwu Bian, Ho-Keung Ng, Li Tang
Pages: 173-180
Published online on: 22 May 2014

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Article

Increased expression of Lgr5 is associated with chemotherapy resistance in human gastric cancer Corrigendum in /10.3892/or.2019.7120

Hong-Qing Xi, Jian-Xin Cui, Wei-Song  Shen, Xiao-Song  Wu, Shi‑Bo  Bian, Ji-Yang  Li, Zhou  Song, Bo  Wei, Lin Chen
Pages: 181-188
Published online on: 22 May 2014

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Article

Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma

Kyong-Won Kang, Mi-Jung Lee, Ji-Ae Song, Ju-Yeon Jeong, Yoo-Kyong Kim, Chan Lee, Tae-Heon Kim, Kyu-Beom Kwak, Ok-Jun Kim, Hee Jung An
Pages: 189-198
Published online on: 20 May 2014

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Article

Interferon-λ1 induces G1 phase cell cycle arrest and apoptosis in gastric carcinoma cells in vitro

Zhitao Gao, Moli Zhu, Yaping Wu, Pan Gao, Zhihai Qin, Hui Wang
Pages: 199-204
Published online on: 15 May 2014

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Article

Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma Corrigendum in /10.3892/or.2017.5455

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Pages: 205-212
Published online on: 20 May 2014

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Article

HGF and the regulation of tight junctions in human prostate cancer cells

Tracey A. Martin, Malcolm D. Mason, Wen G. Jiang
Pages: 213-224
Published online on: 26 May 2014

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Article

Selective suppression of autocatalytic caspase-3 driven by two-step transcriptional amplified human telomerase reverse transcriptase promoter on ovarian carcinoma growth in vitro and in mice

Yue Song, Xing Xin, Zhijun Xia, Xingyue Zhai, Keng Shen
Pages: 225-234
Published online on: 20 May 2014

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Article

Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells

Juan Ma, Li Zhuo Han, He Liang, Chunliu Mi, Hui Shi, Jung Joon Lee, Xuejun Jin
Pages: 235-242
Published online on: 23 May 2014

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Article

Knocking down the expression of Aurora-A gene inhibits cell proliferation and induces G2/M phase arrest in human small cell lung cancer cells

Yimin Lu, Yuanhua Liu, Jianzhong Jiang, Zhaoqing Xi, Ning Zhong, Shunbin Shi, Jinzhi Wang, Xiaodong Wei
Pages: 243-249
Published online on: 16 May 2014

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Article

Integrated analysis using methylation and gene expression microarrays reveals PDE4C as a prognostic biomarker in human glioma

Zhaoshi Bao, Ying Feng, Hongjun Wang, Chuanbao Zhang, Lihua Sun, Zhuohong Yan, Qingyang Liu, Tianzhu Guo, Mingyang Li, Xue Yang, Chuanlu Jiang, Quangeng Zhang, Tao Jiang
Pages: 250-260
Published online on: 15 May 2014

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Article

miR-101, downregulated in retinoblastoma, functions as a tumor suppressor in human retinoblastoma cells by targeting EZH2

Qiong Lei, Fengmei Shen, Jie Wu, Weishan Zhang, Jiahui Wang, Lin Zhang
Pages: 261-269
Published online on: 07 May 2014

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Article

Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia

Kirsten Hattermann, Susanne Sebens, Ole  Helm, Anne   Dorothée Schmitt, Rolf  Mentlein, H.  Maximilian Mehdorn, Janka  Held-Feindt
Pages: 270-276
Published online on: 23 May 2014

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Article

Promoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer

Xiujie Sheng, Jianqi Li, Lei Yang, Zhiyi  Chen, Qin  Zhao, Linyu  Tan, Yanqing  Zhou, Juan Li
Pages: 277-285
Published online on: 22 May 2014

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Article

PinX1 without the G-patch motif suppresses proliferation, induces senescence, but does not inhibit telomerase activity in colorectal cancer SW480 cells

Rui Zhang, Jian Zhao, Xu Wang, Li-Li Wang, Jian Xu, Chun Song
Pages: 286-292
Published online on: 20 May 2014

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Article

Caveolin-1 plays a key role in the oleanolic acid-induced apoptosis of HL-60 cells

Wei Ma, Di-Di Wang, Li Li, Yu-Kuan Feng, Hong-Mei Gu, Gui-Ming Zhu, Jin-Hua Piao, Yu Yang, Xu Gao, Peng-Xia Zhang
Pages: 293-301
Published online on: 15 May 2014

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Article

β1 integrin modulates tumor growth and apoptosis of human colorectal cancer

Jia Song, Jixiang Zhang, Jing Wang, Zhuo Cao, Jun Wang, Xufeng Guo, Weiguo Dong
Pages: 302-308
Published online on: 07 May 2014

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Article

Bioinformatics screening regarding herbal components that targetedly regulate the function of tumour-associated macrophages

Bo Gao, Yingmei Wang, Yan Qiu, Weiliang  Xia, Xianzhi  Meng, Ming  Lu, Weihui  Zhang, Xin  Qiao, Yingmei Zhang, Dongbo Xue
Pages: 309-317
Published online on: 23 May 2014

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Article

Src/caveolin-1-regulated EGFR activation antagonizes TRAIL-induced apoptosis in gastric cancer cells

Ling Xu, Xiujuan Qu, Heming Li, Ce Li, Jing Liu, Huachuan Zheng, Yunpeng Liu
Pages: 318-324
Published online on: 15 May 2014

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Article

Compound K-induced apoptosis of human hepatocellular carcinoma MHCC97-H cells in vitro

Zhi-Zhong Zheng, Yan-Lin Ming, Liang-Hua Chen, Guo-Hua Zheng, Shao-Song Liu, Qing-Xi Chen
Pages: 325-331
Published online on: 08 May 2014

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Article

Non-essential amino acids attenuate apoptosis of gastric cancer cells induced by glucose starvation

Gang Wang, Lei Dai, Laisheng  Luo, Wen  Xu, Chenjing  Zhang, Yimiao  Zhu, Zhongting  Chen, Wen  Hu, Xiang  Xu, Wensheng  Pan
Pages: 332-340
Published online on: 21 May 2014

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Article

Combination of BIBW2992 and ARQ 197 is effective against erlotinib-resistant human lung cancer cells with the EGFR T790M mutation

Geping Qu, Changting Liu, Baojun Sun, Changxi Zhou, Zhijian Zhang, Peng Wang
Pages: 341-347
Published online on: 15 May 2014

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Article

Stromal fibroblasts are predictors of disease-related mortality in esophageal squamous cell carcinoma

Shin Saito, Kazue Morishima, Takashi  Ui, Daisuke  Matsubara, Tomoko  Tamura, Sachiko  Oguni, Yoshinori  Hosoya, Naohiro  Sata, Alan  T. Lefor, Yoshikazu  Yasuda, Toshiro  Niki
Pages: 348-354
Published online on: 23 May 2014

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Article

Gallic acid inhibits migration and invasion of SCC‑4 human oral cancer cells through actions of NF‑κB, Ras and matrix metalloproteinase-2 and -9

Chao-Lin Kuo, Kuang-Chi Lai, Yi-Shih Ma, Shu-Wen Weng, Jing-Pin Lin, Jing-Gung Chung
Pages: 355-361
Published online on: 23 May 2014

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Article

Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer

Fuqiang Yin, Ling Liu, Xia Liu, Gang Li, Li Zheng, Danrong Li, Qi Wang, Wei Zhang, Li Li
Pages: 362-372
Published online on: 13 May 2014

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Article

N-benzyl-N-methyldecan-1-amine, a phenylamine derivative isolated from garlic cloves, induces G2/M phase arrest and apoptosis in U937 human leukemia cells

Jin-Woo Jeong, Sejin Park, Cheol Park, Young-Chae Chang, Dong-Oh Moon, Sung Ok Kim, Gi-Young Kim, Hee-Jae Cha, Heui-Soo Kim, Young-Whan Choi, Wun-Jae Kim, Young Hyun Yoo, Yung Hyun Choi
Pages: 373-381
Published online on: 23 May 2014

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Article

Targeted inhibition of mTORC2 prevents osteosarcoma cell migration and promotes apoptosis

Xiaokai Wang, Pinglin Lai, Zhongmin Zhang, Minjun Huang, Liang Wang, Min Yin, Dadi Jin, Rongping Zhou, Xiaochun Bai
Pages: 382-388
Published online on: 15 May 2014

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Article

Involvement of HIF-1α activation in the doxorubicin resistance of human osteosarcoma cells

Laura Roncuzzi, Fabia Pancotti, Nicola Baldini
Pages: 389-394
Published online on: 15 May 2014

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Article

Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer

Ze-Hua Wu, Xiao-Liang Wang, Hua-Mei Tang, Tao Jiang, Jian Chen, Su Lu, Guo-Qiang Qiu, Zhi-Hai Peng, Dong-Wang Yan
Pages: 395-402
Published online on: 15 May 2014

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Article

Overexpression of ZDHHC14 promotes migration and invasion of scirrhous type gastric cancer

Htoo Zarni Oo, Kazuhiro Sentani, Naoya Sakamoto, Katsuhiro Anami, Yutaka Naito, Naohiro Uraoka, Takashi Oshima, Kazuyoshi Yanagihara, Naohide Oue, Wataru Yasui
Pages: 403-410
Published online on: 06 May 2014

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Article

Downregulation of galectin-3 causes a decrease in uPAR levels and inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells

Datong Zheng, Zhenzhen Hu, Fan He, Caijie Gao, Lijian Xu, Han Zou, Zhiwei Wu, Xiuqin Jiang, Jianjun Wang
Pages: 411-418
Published online on: 08 May 2014

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Article

Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression

Michel D. Wissing, Tikva Dadon, Eunice Kim, Klaus B. Piontek, Joong S. Shim, Nadine S. Kaelber, Jun O. Liu, Sushant K. Kachhap, Barry D. Nelkin
Pages: 419-424
Published online on: 13 May 2014

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Article

Corticotropin-releasing factor induces immune escape of cervical cancer cells by downregulation of NKG2D

Hyunkeun Song, Hyunjin Park, Gabin Park, Yeong Seok Kim, Hyun-Kyung Lee, Dong-Hoon Jin, Hyung-Sik Kang, Dae-Ho Cho, Daeyoung Hur
Pages: 425-430
Published online on: 16 May 2014

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Article

Role and mechanism of the alkylglycerone phosphate synthase in suppressing the invasion potential of human glioma and hepatic carcinoma cells in vitro

Yu Zhu, Lielie Zhu, Ling Lu, Ling Zhang, Guodong Zhang, Qin Wang, Ping Yang
Pages: 431-436
Published online on: 15 May 2014

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January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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