|
1
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar
|
|
2
|
Dalerba P, Cho RW and Clarke MF: Cancer
stem cells: Models and concepts. Annu Rev Med. 58:267–284. 2007.
View Article : Google Scholar
|
|
3
|
Hu Q and Hill RP: Radiosensitivity,
apoptosis and repair of DNA double-strand breaks in
radiation-sensitive Chinese hamster ovary cell mutants treated at
different dose rates. Radiat Res. 146:636–645. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Xiang L, Xie G, Liu C, Zhou J, Chen J, Yu
S, Li J, Pang X, Shi H and Liang H: Knock-down of glutaminase 2
expression decreases glutathione, NADH, and sensitizes cervical
cancer to ionizing radiation. Biochim Biophys Acta. 1833:2996–3005.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Walter P and Ron D: The unfolded protein
response: From stress pathway to homeostatic regulation. Science.
334:1081–1086. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Schröder M and Kaufman RJ: The mammalian
unfolded protein response. Annu Rev Biochem. 74:739–789. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Hetz C, Martinon F, Rodriguez D and
Glimcher LH: The unfolded protein response: Integrating stress
signals through the stress sensor IRE1α. Physiol Rev. 91:1219–1243.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ron D and Walter P: Signal integration in
the endoplasmic reticulum unfolded protein response. Nat Rev Mol
Cell Biol. 8:519–529. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yoshida H, Matsui T, Yamamoto A, Okada T
and Mori K: XBP1 mRNA is induced by ATF6 and spliced by IRE1 in
response to ER stress to produce a highly active transcription
factor. Cell. 107:881–891. 2001. View Article : Google Scholar
|
|
10
|
Yamamori T, Meike S, Nagane M, Yasui H and
Inanami O: ER stress suppresses DNA double-strand break repair and
sensitizes tumor cells to ionizing radiation by stimulating
proteasomal degradation of Rad51. FEBS Lett. 587:3348–3353. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Johnson GG, White MC and Grimaldi M:
Stressed to death: Targeting endoplasmic reticulum stress response
induced apoptosis in gliomas. Curr Pharm Des. 17:284–292. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Huang HJ, Lin CC, Chou HC, Chen YW, Lin
ST, Lin YC, Lin DY, Lyu KW and Chan HL: Proteomic analysis of
rhein-induced cyt: ER stress mediates cell death in breast cancer
cells. Mol Biosyst. 10:3086–3100. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Saglar E, Unlu S, Babalioglu I, Gokce SC
and Mergen H: Assessment of ER stress and autophagy induced by
ionizing radiation in both radiotherapy patients and ex vivo
irradiated samples. J Biochem Mol Toxicol. 28:413–417. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
El-Deiry WS: The role of p53 in
chemosensitivity and radiosensitivity. Oncogene. 22:7486–7495.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Weilbacher A, Gutekunst M, Oren M,
Aulitzky WE and van der Kuip H: RITA can induce cell death in
p53-defective cells independently of p53 function via activation of
JNK/SAPK and p38. Cell Death Dis. 5:e13182014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Issaeva N, Bozko P, Enge M, Protopopova M,
Verhoef LG, Masucci M, Pramanik A and Selivanova G: Small molecule
RITA binds to p53, blocks p53-HDM-2 interaction and activates p53
function in tumors. Nat Med. 10:1321–1328. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Chuang HC, Yang LP, Fitzgerald AL, Osman
A, Woo SH, Myers JN and Skinner HD: The p53-reactivating small
molecule RITA induces senescence in head and neck cancer cells.
PLoS One. 9:e1048212014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Yaginuma Y and Westphal H: Analysis of the
p53 gene in human uterine carcinoma cell lines. Cancer Res.
51:6506–6509. 1991.PubMed/NCBI
|
|
19
|
Srivastava S, Tong YA, Devadas K, Zou ZQ,
Chen Y, Pirollo KF and Chang EH: The status of the p53 gene in
human papilloma virus positive or negative cervical carcinoma cell
lines. Carcinogenesis. 13:1273–1275. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhao CY, Szekely L, Bao W and Selivanova
G: Rescue of p53 function by small-molecule RITA in cervical
carcinoma by blocking E6-mediated degradation. Cancer Res.
70:3372–3381. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Byun K, Bayarsaikhan E, Kim D, Kim CY,
Mook-Jung I, Paek SH, Kim SU, Yamamoto T, Won MH, Song BJ, et al:
Induction of neuronal death by microglial AGE-albumin: Implications
for Alzheimer's disease. PLoS One. 7:e379172012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zhao CY, Grinkevich VV, Nikulenkov F, Bao
W and Selivanova G: Rescue of the apoptotic-inducing function of
mutant p53 by small molecule RITA. Cell Cycle. 9:1847–1855. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
van Schadewijk A, van't Wout EF, Stolk J
and Hiemstra PS: A quantitative method for detection of spliced
X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic
reticulum (ER) stress. Cell Stress Chaperones. 17:275–279. 2012.
View Article : Google Scholar :
|
|
24
|
Lin WC, Chuang YC, Chang YS, Lai MD, Teng
YN, Su IJ, Wang CC, Lee KH and Hung JH: Endoplasmic reticulum
stress stimulates p53 expression through NF-κB activation. PLoS
One. 7:e391202012. View Article : Google Scholar
|
|
25
|
Mlynarczyk C and Fåhraeus R: Endoplasmic
reticulum stress sensitizes cells to DNA damage-induced apoptosis
through p53-dependent suppression of p21(CDKN1A). Nat Commun.
5:50672014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Qu L, Huang S, Baltzis D, Rivas-Estilla
AM, Pluquet O, Hatzoglou M, Koumenis C, Taya Y, Yoshimura A and
Koromilas AE: Endoplasmic reticulum stress induces p53 cytoplasmic
localization and prevents p53-dependent apoptosis by a pathway
involving glycogen synthase kinase-3beta. Genes Dev. 18:261–277.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Pluquet O, Qu LK, Baltzis D and Koromilas
AE: Endoplasmic reticulum stress accelerates p53 degradation by the
cooperative actions of Hdm2 and glycogen synthase kinase 3beta. Mol
Cell Biol. 25:9392–9405. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Pan JM, Zhou L, Wang GB, Xia GW, Xue K,
Cui XG, Shi HZ, Liu JH and Hu J: Fatsioside A inhibits the growth
of glioma cells via the induction of endoplasmic reticulum
stress-mediated apoptosis. Mol Med Rep. 11:3493–3498.
2015.PubMed/NCBI
|
|
29
|
Chiu HW, Tseng YC, Hsu YH, Lin YF, Foo NP,
Guo HR and Wang YJ: Arsenic trioxide induces programmed cell death
through stimulation of ER stress and inhibition of the
ubiquitinproteasome system in human sarcoma cells. Cancer Lett.
356:762–772. 2015. View Article : Google Scholar
|
