|
1
|
Araya N, Sato T, Yagishita N, Ando H,
Utsunomiya A, Jacobson S and Yamano Y: Human T-lymphotropic virus
type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated
neuroinflammatory disease. Viruses. 3:1532–1548. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hinuma Y, Nagata K, Hanaoka M, Nakai M,
Matsumoto T, Kinoshita KI, Shirakawa S and Miyoshi I: Adult T-cell
leukemia: Antigen in an ATL cell line and detection of antibodies
to the antigen in human sera. Proc Natl Acad Sci USA. 78:6476–6480.
1981. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cann AJ, Rosenblatt JD, Wachsman W, Shah
NP and Chen IS: Identification of the gene responsible for human T-
cell leukaemia virus transcriptional regulation. Nature.
318:571–574. 1985. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Felber BK, Paskalis H, Kleinman-Ewing C,
Wong-Staal F and Pavlakis GN: The pX protein of HTLV-I is a
transcriptional activator of its long terminal repeats. Science.
229:675–679. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sodroski J, Rosen C, Goh WC and Haseltine
W: A transcriptional activator protein encoded by the x-lor region
of the human T-cell leukemia virus. Science. 228:1430–1434. 1985.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Grassmann R, Berchtold S, Radant I, Alt M,
Fleckenstein B, Sodroski JG, Haseltine WA and Ramstedt U: Role of
human T-cell leukemia virus type 1 X region proteins in
immortalization of primary human lymphocytes in culture. J Virol.
66:4570–4575. 1992.PubMed/NCBI
|
|
7
|
Siekevitz M, Feinberg MB, Holbrook N,
Wong-Staal F and Greene WC: Activation of interleukin 2 and
interleukin 2 receptor (Tac) promoter expression by the trans
activator (tat) gene product of human T-cell leukemia virus, type
I. Proc Natl Acad Sci USA. 84:5389–5393. 1987. View Article : Google Scholar
|
|
8
|
Ballard DW, Bohnlein E, Lowenthal JW, Wano
Y, Franza BR and Greene WC: HTLV-I tax induces cellular proteins
that activate the kappa B element in the IL-2 receptor alpha gene.
Science. 241:1652–1655. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Leung KY and Nabel GJ: HTLV-1
transactivator induces interleukin-2 receptor expression through an
NF-kappa B-like factor. Nature. 333:776–778. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Franchini G: Molecular mechanisms of human
T-cell leukemia/ lymphotropic virus type I infection. Blood.
86:3619–3639. 1995.PubMed/NCBI
|
|
11
|
Franklin AA and Nyborg JK: Mechanisms of
Tax regulation of human T cell leukemia virus type I gene
expression. J Biomed Sci. 2:17–29. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Bergers G, Graninger P, Braselmann S,
Wrighton C and Busslinger M: Transcriptional activation of the
fra-1 gene by AP-1 is mediated by regulatory sequences in the first
intron. Mol Cell Biol. 15:3748–3758. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Angel P and Karin M: The role of Jun, Fos
and the AP-1 complex in cell-proliferation and transformation.
Biochim Biophys Acta. 1072:129–157. 1991.PubMed/NCBI
|
|
14
|
Fuchs SY, Xie B, Adler V, Fried VA, Davis
RJ and Ronai Z: c-Jun NH2-terminal kinases target the
ubiquitination of their associated transcription factors. J Biol
Chem. 272:32163–32168. 1997. View Article : Google Scholar
|
|
15
|
Yao M, Nguyen TV and Pike CJ:
Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal
kinase-dependent down-regulation of Bcl-w. J Neurosci.
25:1149–1158. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Widmann C, Gibson S, Jarpe MB and Johnson
GL: Mitogen-activated protein kinase: Conservation of a
three-kinase module from yeast to human. Physiol Rev. 79:143–180.
1999.PubMed/NCBI
|
|
17
|
Xia Z, Dickens M, Raingeaud J, Davis RJ
and Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases
on apoptosis. Science. 270:1326–1331. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Behrens A, Sibilia M and Wagner EF:
Amino-terminal phosphorylation of c-Jun regulates stress-induced
apoptosis and cellular proliferation. Nat Genet. 21:326–329. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhang CC and Shapiro DJ: Activation of the
p38 mitogen-activated protein kinase pathway by estrogen or by
4-hydroxytamoxifen is coupled to estrogen receptor-induced
apoptosis. J Biol Chem. 275:479–486. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yu R, Mandlekar S, Tan TH and Kong AN:
Activation of p38 and c-Jun N-terminal kinase pathways and
induction of apoptosis by chelerythrine do not require inhibition
of protein kinase C. J Biol Chem. 275:9612–9619. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hoffmann E, Ashouri J, Wolter S, Doerrie
A, Dittrich-Breiholz O, Schneider H, Wagner EF, Troppmair J,
Mackman N and Kracht M: Transcriptional regulation of EGR-1 by the
interleukin-1-JNK-MKK7-c-Jun pathway. J Biol Chem. 283:12120–12128.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Parra E, Ferreira J and Ortega A:
Overexpression of EGR-1 modulates the activity of NF-κB and AP-1 in
prostate carcinoma PC-3 and LNCaP cell lines. Int J Oncol.
39:345–352. 2011.PubMed/NCBI
|
|
23
|
Parra E and Ferreira J: The effect of
siRNA-Egr-1 and camptothecin on growth and chemosensitivity of
breast cancer cell lines. Oncol Rep. 23:1159–1165. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Parra E, Ortega A and Saenz L:
Down-regulation of Egr-1 by siRNA inhibits growth of human prostate
carcinoma cell line PC-3. Oncol Rep. 22:1513–1518. 2009.PubMed/NCBI
|
|
25
|
Liu C, Yao J, Mercola D and Adamson E: The
transcription factor EGR-1 directly transactivates the fibronectin
gene and enhances attachment of human glioblastoma cell line U251.
J Biol Chem. 275:20315–20323. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Calogero A, Arcella A, De Gregorio G,
Porcellini A, Mercola D, Liu C, Lombari V, Zani M, Giannini G,
Gagliardi FM, et al: The early growth response gene EGR-1 behaves
as a suppressor gene that is down-regulated independent of ARF/Mdm2
but not p53 alterations in fresh human gliomas. Clin Cancer Res.
7:2788–2796. 2001.PubMed/NCBI
|
|
27
|
Zhang H, Chen X, Wang J, Guang W, Han W,
Zhang H, Tan X and Gu Y: EGR1 decreases the malignancy of human
non-small cell lung carcinoma by regulating KRT18 expression. Sci
Rep. 4:54162014.PubMed/NCBI
|
|
28
|
Parra E, Varga M, Hedlund G, Kalland T and
Dohlsten M: Costimulation by B7-1 and LFA-3 targets distinct
nuclear factors that bind to the interleukin-2 promoter: B7-1
negatively regulates LFA-3-induced NF-AT DNA binding. Mol Cell
Biol. 17:1314–1323. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Parra E, Varga M, Sigvardsson M, Hedlund
G, Kalland T, Leanderson T, Sjogren H and Dohlsten M: Costimulation
of human CD4+ T cells with LFA-3 and B7 induce distinct
effects on AP-1 and NF-kappa B transcription factors. J Immunol.
155:1132–1140. 1995.PubMed/NCBI
|
|
30
|
Parra E: Activation of MAP kinase family
members triggered by TPA or ionomycin occurs via the protein
phosphatase 4 pathway in Jurkat leukemia T cells. Mol Med Rep.
5:773–778. 2012.
|
|
31
|
Parra E and Gutiérrez L: Growth inhibition
of Tax-activated human Jurkat leukemia T cells by all-trans
retinoic acid requires JNK-1 inhibition. Oncol Rep. 29:387–393.
2013.
|
|
32
|
Azran I, Schavinsky-Khrapunsky Y and Aboud
M: Role of Tax protein in human T-cell leukemia virus type-I
leukemogenicity. Retrovirology. 1:202004. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Good L, Maggirwar SB and Sun SC:
Activation of the IL-2 gene promoter by HTLV-I tax involves
induction of NF-AT complexes bound to the CD28-responsive element.
EMBO J. 15:3744–3750. 1996.PubMed/NCBI
|
|
34
|
Harhaj EW and Harhaj NS: Mechanisms of
persistent NF-kappaB activation by HTLV-I tax. IUBMB Life.
57:83–91. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Li XH, Murphy KM, Palka KT, Surabhi RM and
Gaynor RB: The human T-cell leukemia virus type-1 Tax protein
regulates the activity of the IkappaB kinase complex. J Biol Chem.
274:34417–34424. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Xiao G and Sun SC: Activation of IKKalpha
and IKKbeta through their fusion with HTLV-I tax protein. Oncogene.
19:5198–5203. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Petropoulos L, Lin R and Hiscott J: Human
T cell leukemia virus type 1 tax protein increases NF-kappa B dimer
formation and antagonizes the inhibitory activity of the I kappa B
alpha regulatory protein. Virology. 225:52–64. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Verma IM: Nuclear factor (NF)-kappaB
proteins: Therapeutic targets. Ann Rheum Dis. 63(Suppl 2):
ii57–ii61. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Holmes WF, Soprano DR and Soprano KJ:
Synthetic retinoids as inducers of apoptosis in ovarian carcinoma
cell lines. J Cell Physiol. 199:317–329. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zhang XK: Vitamin A and apoptosis in
prostate cancer. Endocr Relat Cancer. 9:87–102. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Zhang D, Holmes WF, Wu S, Soprano DR and
Soprano KJ: Retinoids and ovarian cancer. J Cell Physiol. 185:1–20.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Liu C, Rangnekar VM, Adamson E and Mercola
D: Suppression of growth and transformation and induction of
apoptosis by EGR-1. Cancer Gene Ther. 5:3–28. 1998.PubMed/NCBI
|
|
43
|
Virolle T, Adamson ED, Baron V, Birle D,
Mercola D, Mustelin T and de Belle I: The Egr-1 transcription
factor directly activates PTEN during irradiation-induced
signalling. Nat Cell Biol. 3:1124–1128. 2001. View Article : Google Scholar
|
|
44
|
Chen L, Wang S, Zhou Y, Wu X, Entin I,
Epstein J, Yaccoby S, Xiong W, Barlogie B, Shaughnessy JD Jr, et
al: Identification of early growth response protein 1 (EGR-1) as a
novel target for JUN-induced apoptosis in multiple myeloma. Blood.
115:61–70. 2010. View Article : Google Scholar :
|
|
45
|
Park JM, Greten FR, Li ZW and Karin M:
Macrophage apoptosis by anthrax lethal factor through p38 MAP
kinase inhibition. Science. 297:2048–2051. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Juretic N, Santibanez JF, Hurtado C and
Martinez J: ERK 1,2 and p38 pathways are involved in the
proliferative stimuli mediated by urokinase in osteoblastic SaOS-2
cell line. J Cell Biochem. 83:92–98. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Halawani D, Mondeh R, Stanton LA and Beier
F: p38 MAP kinase signaling is necessary for rat chondrosarcoma
cell proliferation. Oncogene. 23:3726–3731. 2004. View Article : Google Scholar : PubMed/NCBI
|
