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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2016 Volume 35 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

ARID1A gene mutation in ovarian and endometrial cancers (Review)

Takashi Takeda, Kouji Banno, Ryuichiro Okawa, Megumi Yanokura, Moito Iijima, Haruko Irie‑Kunitomi, Kanako Nakamura, Miho Iida, Masataka Adachi, Kiyoko Umene, Yuya Nogami, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki
Pages: 607-613
Published online on: 16 November 2015

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Review

The roles of microRNAs in the pathogenesis and drug resistance of chronic myelogenous leukemia (Review)

Carla Di Stefano, Giovanna Mirone, Stefania Perna, Gabriella Marfe
Pages: 614-624
Published online on: 26 November 2015

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Review

Protein-protein interactions among signaling pathways may become new therapeutic targets in liver cancer (Review)

Xiao Zhang, Yulan Wang, Jiayi Wang, Fenyong Sun
Pages: 625-638
Published online on: 27 November 2015

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Review

Novel cellular and post-genomic technologies in the treatment of glioblastoma multiforme (Review)

Igor Bryukhovetskiy, Andrey Bryukhovetskiy, Yuri Khotimchenko, Polina Mischenko
Pages: 639-648
Published online on: 06 November 2015

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Article Open Access

Reduction of apoptosis by proanthocyanidin-induced autophagy in the human gastric cancer cell line MGC-803

Chao Nie, Jie Zhou, Xiaokang Qin, Xianming Shi, Qingqi Zeng, Jia Liu, Shihai Yan, Lei Zhang
Pages: 649-658
Published online on: 13 November 2015

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Article Open Access

An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract

Ailun Tseng, Chih-Hsueh Yang, Chih-Hao Chen, Chang-Han Chen, Shih-Lan Hsu, Mei-Hsien Lee, Hoong-Chien Lee, Li-Jen Su
Pages: 659-668
Published online on: 23 November 2015

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Article Open Access

Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway

Xiangqian Zhao, Kai Jiang, Bin Liang, Xiaoqiang Huang
Pages: 669-675
Published online on: 26 November 2015

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Article

The dipeptidyl peptidase-4 inhibitor sitagliptin suppresses mouse colon tumorigenesis in type 2 diabetic mice

Naoki Yorifuji, Takuya Inoue, Munetaka Iguchi, Kaori Fujiwara, Kazuki Kakimoto, Sadaharu Nouda, Toshihiko Okada, Ken Kawakami, Yosuke Abe, Toshihisa Takeuchi, Kazuhide Higuchi
Pages: 676-682
Published online on: 16 November 2015

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Article

miR-181b promotes chemoresistance in breast cancer by regulating Bim expression

Yabing Zheng, Xiaoai Lv, Xiaojia Wang, Bei Wang, Xiying Shao, Yuan Huang, Lei Shi, Zhanhong Chen, Jian Huang, Ping Huang
Pages: 683-690
Published online on: 13 November 2015

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Article

131I therapy mediated by sodium/iodide symporter combined with kringle 5 has a synergistic therapeutic effect on glioma

Shuo Shi, Min Zhang, Rui Guo, Miao Zhang, Jiajia Hu, Yun Xi, Ying Miao, Biao Li
Pages: 691-698
Published online on: 13 November 2015

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Article

Relationship between expression of PD-L1 and PD-L2 on esophageal squamous cell carcinoma and the antitumor effects of CD8+ T cells

Changsen Leng, Yin Li, Jianjun Qin, Jun Ma, Xianben Liu, Yingying Cui, Haibo Sun, Zongfei Wang, Xionghuai Hua, Yongkui Yu, Haomiao Li, Jun Zhang, Yan Zheng, Wei Wang, Junwei Zhu, Qiuming Wang
Pages: 699-708
Published online on: 17 November 2015

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Article

miR-340 suppresses cell migration and invasion by targeting MYO10 in breast cancer

Cai‑Ping Chen, Zong‑Lin Sun, Xiang Lu, Wan‑Xin Wu, Wen‑Li Guo, Jian‑Ju Lu, Chao Han, Jian‑Qi Huang, Ying Fang
Pages: 709-716
Published online on: 12 November 2015

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Article

β-catenin is regulated by USP9x and mediates resistance to TRAIL-induced apoptosis in breast cancer

Wen Ouyang, Shimin Zhang, Bo Yang, Chunxu Yang, Junhong Zhang, Fuxiang Zhou, Conghua Xie
Pages: 717-724
Published online on: 27 November 2015

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Article

A novel somatic MAPK1 mutation in primary ovarian mixed germ cell tumors

Yang Zou, Wei Deng, Feng Wang, Xiao‑Hong Yu, Fa‑Ying Liu, Bi‑Cheng Yang, Mei‑Zhen Huang, Jiu‑Bai Guo, Qiu‑Hua Xie, Ming He, Ou‑Ping Huang
Pages: 725-730
Published online on: 05 November 2015

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Article

Therapeutic effects of bone marrow-derived mesenchymal stem cells on radiation-induced lung injury

Chengcheng Xia, Pengyu Chang, Yuyu Zhang, Weiyan Shi, Bin Liu, Lijuan Ding, Min Liu, Ling Gao, Lihua Dong
Pages: 731-738
Published online on: 17 November 2015

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Article

Gut-derived serotonin induced by depression promotes breast cancer bone metastasis through the RUNX2/PTHrP/RANKL pathway in mice

Jian‑Chun Zong, Xing Wang, Xiang Zhou, Chen Wang, Liang Chen, Liang‑Jun Yin, Bai‑Cheng He, Zhong‑Liang Deng
Pages: 739-748
Published online on: 16 November 2015

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Article

Genetic network profiles associated with established resistance to ionizing radiation in acute promyelocytic leukemia cells and their extracellular vesicles

Satoru Monzen, Mitsuru Chiba, Yoichiro Hosokawa
Pages: 749-756
Published online on: 02 December 2015

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Article

Microarray profiling of bone marrow long non-coding RNA expression in Chinese pediatric acute myeloid leukemia patients

Lan Cao, Pei-Fang Xiao, Yan-Fang Tao, Shao-Yan Hu, Jun Lu, Wen-Li Zhao, Zhi-Heng Li, Na-Na Wang, Jian Wang, Xing Feng, Yi-Huan Chai, Jian Pan, Gui-Xiong Gu
Pages: 757-770
Published online on: 12 November 2015

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Article

EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P-gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Pages: 771-778
Published online on: 25 November 2015

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Article

10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity

Ji-Hye Joo, Seong-Su Hong, Young-Rak Cho, Dong-Wan Seo
Pages: 779-784
Published online on: 09 November 2015

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Article

A method for establishing a patient-derived xenograft model to explore new therapeutic strategies for esophageal squamous cell carcinoma

Yanan Jiang, Qiong Wu, Xiawen Yang, Jimin Zhao, Yuxi Jin, Ke Li, Yihui Ma, Xinhuan Chen, Fang Tian, Song Zhao, Jinglong Xu, Jing Lu, Xueshan Yin, Kangdong Liu, Ziming Dong
Pages: 785-792
Published online on: 26 November 2015

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Article

Antitumor activity of a novel small molecule TLR7 agonist via immune response induction and tumor microenvironment modulation

Yuwen Diao, Xiaodong Wang, Yanyan Wan, Jingjing Zhong, Dong Gao, Yu Liu, Ningning Gao, Wang Li, Bing Liu, Xinping Huang, Zhenchao Jin, Boya Peng, Zhulin Wang, Li Fu, Siping Chen, Guangyi Jin
Pages: 793-800
Published online on: 18 November 2015

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Article

Rituximab-conjugated and doxorubicin-loaded microbubbles combined with ultrasound irradiation inhibits proliferation and induces apoptosis in Raji cell lines

Shoubing Zhou, Shiya Zheng, Yongfeng Shan, Lulu Li, Xiu Zhang, Cailian Wang
Pages: 801-808
Published online on: 01 December 2015

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Article

Apoptosis-related protein-1 acts as a tumor suppressor in cholangiocarcinoma cells by inducing cell cycle arrest via downregulation of cyclin-dependent kinase subunits

Jianyong Zheng, Qinlong Li, Weihua Wang, Yingmei Wang, Xin Fu, Wenyong Wang, Linni Fan, Wei Yan
Pages: 809-816
Published online on: 16 November 2015

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Article

Expression of prion protein is closely associated with pathological and clinical progression and abnormalities of p53 in head and neck squamous cell carcinomas

Wei Wei, Qi Shi, Nai-Song Zhang, Kang Xiao, Li-Na Chen, Xiao‑Dong Yang, Jia-Fu Ji, Xiao-Ping Dong
Pages: 817-824
Published online on: 16 November 2015

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Article

Luteolin suppresses development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats

Matthew T. Cook, Benford Mafuvadze, Cynthia Besch-Williford, Mark R. Ellersieck, Sandy Goyette, Salman M. Hyder
Pages: 825-832
Published online on: 17 November 2015

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Article

Isoalantolactone induces autophagic cell death in SKOV3 human ovarian carcinoma cells via upregulation of PEA-15

Zhiyong Weng, Hongguo Gao, Jiehua Hu, Yonggang Fan, Hongyan Wang, Lihua Li
Pages: 833-840
Published online on: 26 November 2015

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Article

Identification of novel therapeutic targets in the secretome of ionizing radiation‑induced senescent tumor cells

Hyun Jung Hwang, Seung Hee Jung, Hyung Chul Lee, Na Kyung Han, In Hwa Bae, Minyoung Lee, Young‑Hoon Han, Young‑Sun Kang, Su‑Jae Lee, Heon Joo Park, Young‑Gyu Ko, Jae‑Seon Lee
Pages: 841-850
Published online on: 02 December 2015

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Article

Galectin-9 suppresses the proliferation of gastric cancer cells in vitro

Jitsuko Takano, Asahiro Morishita, Shintaro Fujihara, Hisakazu Iwama, Fuyuko Kokado, Keiko Fujikawa, Koji Fujita, Taiga Chiyo, Tomoko Tadokoro, Teppei Sakamoto, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Hideki Kobara, Hirohito Mori, Toshihiro Niki, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 851-860
Published online on: 26 November 2015

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Article

Effects of curcumin on cancer cell mitochondrial function and potential monitoring with 18F-FDG uptake

Kyung-Ho Jung, Jin Hee Lee, Jin Won Park, Seung-Hwan Moon, Young Seok Cho, Yearn Seong Choe, Kyung-Han Lee
Pages: 861-868
Published online on: 26 November 2015

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Article

miR-218-5p inhibits the stem cell properties and invasive ability of the A2B5+CD133- subgroup of human glioma stem cells Retraction in /10.3892/or.2022.8383

Zhiwu Wu, Yong Han, Yanyan Li, Xuetao Li, Ting Sun, Guilin Chen, Yulun Huang, Youxin Zhou, Ziwei Du
Pages: 869-877
Published online on: 13 November 2015

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Article

Digitoxin and its synthetic analog MonoD have potent antiproliferative effects on lung cancer cells and potentiate the effects of hydroxyurea and paclitaxel

Juan Sebastian Yakisich, Neelam Azad, Rajkumar Venkatadri, Yogesh Kulkarni, Clayton Wright, Vivek Kaushik, George A. O'Doherty, Anand Krishnan V. Iyer
Pages: 878-886
Published online on: 12 November 2015

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Article

MicroRNA-340 inhibits prostate cancer cell proliferation and metastasis by targeting the MDM2-p53 pathway

Kai Huang, Yuxin Tang, Leye He, Yingbo Dai
Pages: 887-895
Published online on: 26 November 2015

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Article

Hispolon inhibits breast cancer cell migration by reversal of epithelial-to-mesenchymal transition via suppressing the ROS/ERK/Slug/E-cadherin pathway Corrigendum in /10.3892/or.2024.8793

Zhao Zhao, Yi-Sheng Sun, Wei Chen, Long-Xian Lv, Yong-Quan Li
Pages: 896-904
Published online on: 25 November 2015

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Article

Expression of LMP and EBNA genes in Epstein-Barr virus-associated lymphomas in Hu-PBL/SCID mice

Yunlian Tang, Suli Lu, Xiaoning Gan, Fang Liu, Yang Zhang, Chunyan Luo, Yuxia Pan, Li Hong, Ruliang Gan
Pages: 905-911
Published online on: 05 November 2015

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Article

Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway

Ying-Zi Fu, Yuan-Yuan Yan, Miao He, Qing-Huan Xiao, Wei-Fan Yao, Lin Zhao, Hui-Zhe Wu, Zhao-Jin Yu, Ming-Yi Zhou, Mu-Tian Lv, Shan-Shan Zhang, Jian-Jun Chen, Min-Jie Wei
Pages: 912-922
Published online on: 17 November 2015

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Article

Downregulation of Bmi-1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem-like cells Retraction in /10.3892/or.2025.9032

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Pages: 923-931
Published online on: 12 November 2015

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Article

Significance of TGFBR3 allelic loss in the deregulation of TGFβ signaling in primary human endometrial carcinomas

Piotr K. Zakrzewski, Maria Nowacka‑Zawisza, Andrzej Semczuk, Tomasz Rechberger, Krzysztof Gałczyński, Wanda M. Krajewska
Pages: 932-938
Published online on: 05 November 2015

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Article

BMP9/p38 MAPK is essential for the antiproliferative effect of resveratrol on human colon cancer

Shuang-Xue Yuan, Dong-Xu Wang, Qiu-Xiang Wu, Chun-Mei Ren, Yang Li, Qian-Zhao Chen, Yu-Hua Zeng, Ying Shao, Jun-Qin Yang, Yan Bai, Pu Zhang, Yu Yu, Ke Wu, Wen-Juan Sun, Bai-Cheng He
Pages: 939-947
Published online on: 10 November 2015

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Article

Histone deacetylase 4 increases progressive epithelial ovarian cancer cells via repression of p21 on fibrillar collagen matrices

Yu-Fei Shen, Ai-Min Wei, Qing Kou, Qiao-Ying Zhu, Lei Zhang
Pages: 948-954
Published online on: 16 November 2015

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Article

ERK signaling mediates long-term low concentration 3,3'-diindolylmethane inhibited nasopharyngeal carcinoma growth and metastasis: An in vitro and in vivo study

Fen Li, Chen Chen, Shi-Ming Chen, Bo-Kui Xiao, Ze-Zhang Tao
Pages: 955-961
Published online on: 16 November 2015

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Article

An integrated analysis of cancer genes in thyroid cancer

Li Chai, Jia Li, Zhongwei Lv
Pages: 962-970
Published online on: 01 December 2015

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Article

KIF1B promotes glioma migration and invasion via cell surface localization of MT1-MMP

Songyu Chen, Mingzhi Han, Weiliang Chen, Ying He, Bin Huang, Peng Zhao, Qibing Huang, Liang Gao, Xun Qu, Xingang Li
Pages: 971-977
Published online on: 16 November 2015

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Article

Magnetic gold nanoparticle-mediated small interference RNA silencing Bag-1 gene for colon cancer therapy

Wenbai Huang, Zhan'ao Liu, Guanzhou Zhou, Ailing Tian, Nianfeng Sun
Pages: 978-984
Published online on: 26 November 2015

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Article

Study on the inhibition of hyperthermic CO2 pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism

Jiaying Zhao, Yuankun Cai, Chenqing Yin, You Lv, Wanmin Wei, Xin Wang, Zong Hao, Chenxia Shen, Huipeng Wang, Jun Chen
Pages: 985-991
Published online on: 25 November 2015

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Article

Hypoxia inducible factor-1 mediates upregulation of urokinase-type plasminogen activator receptor gene transcription during hypoxia in cervical cancer cells

Hirotaka Nishi, Toru Sasaki, Yuzo Nagamitsu, Fumitoshi Terauchi, Takeshi Nagai, Toshitaka Nagao, Keiichi Isaka
Pages: 992-998
Published online on: 25 November 2015

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Article

CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling

Tao Xiang, Feng Yu, Rushan Fei, Jing Qian, Wenbin Chen
Pages: 999-1005
Published online on: 27 November 2015

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Article

FZD2 inhibits the cell growth and migration of salivary adenoid cystic carcinomas

Lin-Can Ding, Xiao-Yu Huang, Fei-Fei Zheng, Jian Xie, Lin She, Yan Feng, Bo-Hua Su, Da-Li Zheng, You-Guang Lu
Pages: 1006-1012
Published online on: 19 February 2015

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Article

Pro-apoptotic effects of splice-switching oligonucleotides targeting Bcl-x pre-mRNA in human glioma cell lines

Zhaohui Li, Qingwei Li, Liang Han, Nan Tian, Qianlei Liang, Yanzhe Li, Xingli Zhao, Chao Du, Yu Tian
Pages: 1013-1019
Published online on: 30 November 2015

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Article

Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors

Ji‑Hun Kim, Yu Chul Kim, Byoungduck Park
Pages: 1020-1026
Published online on: 20 November 2015

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Article

Aberrant GRK6 promoter methylation is associated with poor prognosis in hypopharyngeal squamous cell carcinoma

Xiaoxia Qiu, Jianqiu Chen, Zhenxin Zhang, Yiwen You, Zhiwei Wang
Pages: 1027-1033
Published online on: 01 December 2015

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Article

Ginkgetin exerts growth inhibitory and apoptotic effects on osteosarcoma cells through inhibition of STAT3 and activation of caspase-3/9

Min Xiong, Lin Wang, Hua‑Long Yu, Heng Han, Dan Mao, Jie Chen, Yun Zeng, Ning He, Zhi‑Gang Liu, Zhi‑Yong Wang, Shou‑Jia Xu, Le-Yun Guo, Yong-An Wang
Pages: 1034-1040
Published online on: 16 November 2015

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Article

MARCKSL1 exhibits anti-angiogenic effects through suppression of VEGFR-2-dependent Akt/PDK-1/mTOR phosphorylation

Boh-Ram Kim, Seung-Hoon Lee, Mi-Sun Park, Seung-Hee Seo, Young-Min Park, Young-Joo Kwon, Seung-Bae Rho
Pages: 1041-1048
Published online on: 10 November 2015

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Article

Cul1 promotes melanoma cell proliferation by promoting DEPTOR degradation and enhancing cap-dependent translation

Lan Chen, Tianyu Liu, Yunhua Tu, Dongyun Rong, Yu Cao
Pages: 1049-1056
Published online on: 23 November 2015

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Article

miR-506 functions as a tumor suppressor in glioma by targeting STAT3 Retraction in /10.3892/or.2021.8212

Tao Peng, Lixiang Zhou, Ling Zuo, Yongxin Luan
Pages: 1057-1064
Published online on: 09 November 2015

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Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells

Guangming Zhao, Xiaodong Han, Siwen Zheng, Zhen Li, Yang Sha, Jing Ni, Zhe Sun, Song Qiao, Zhiqi Song
Pages: 1065-1074
Published online on: 12 November 2015

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miR-331-3p inhibits proliferation and promotes apoptosis by targeting HER2 through the PI3K/Akt and ERK1/2 pathways in colorectal cancer

Dongli Zhao, Yanxia Sui, Xiaoqiang Zheng
Pages: 1075-1082
Published online on: 26 November 2015

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Reciprocal negative feedback loop between EZH2 and miR-101-1 contributes to miR-101 deregulation in hepatocellular carcinoma Expression of Concern in /10.3892/or.2025.8997

Da Huang, Xiaobei Wang, Chunbo Zhuang, Wuhe Shi, Mu Liu, Qiming Tu, Detai Zhang, Lihua Hu
Pages: 1083-1090
Published online on: 01 December 2015

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Article

Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins

Bashir A. Yousef, Mounia Guerram, Hozeifa M. Hassan, Aida M. Hamdi, Lu-Yong Zhang, Zhen-Zhou Jiang
Pages: 1091-1100
Published online on: 26 November 2015

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Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells

Lei Gao, Zhen Xu, Yan Wang, Bin Sun, Zhicheng Song, Bining Yang, Xu Liu, Yuan Lin, Jinyong Peng, Guozhu Han, Shisheng Wang, Zeyao Tang
Pages: 1101-1108
Published online on: 25 November 2015

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Article

β-lapachone suppresses the proliferation of human malignant melanoma cells by targeting specificity protein 1

Woong Bang, Young-Joo Jeon, Jin Hyoung Cho, Ra Ham Lee, Seon-Min Park, Jae-Cheon Shin, Nag-Jin Choi, Yung Hyun Choi, Jung-Jae Cho, Jae-Min Seo, Seung-Yeop Lee, Jung-Hyun Shim, Jung-Il Chae
Pages: 1109-1116
Published online on: 20 November 2015

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Article

Suppression of nucleosome-binding protein 1 by miR-326 impedes cell proliferation and invasion in non-small cell lung cancer cells

Dongfan Li, Xusheng Du, An Liu, Peng Li
Pages: 1117-1124
Published online on: 06 November 2015

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Article

MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-β1 Retraction in /10.3892/or.2022.8324

Qizhuang Li, Quan Cheng, Zigui Chen, Renjun Peng, Rui Chen, Zhiming Ma, Xin Wan, Jincan Liu, Ming Meng, Zhigang Peng, Bing Jiang
Pages: 1125-1134
Published online on: 17 November 2015

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Article

Integrated analysis of the miRNA, gene and pathway regulatory network in gastric cancer

Haiyang Zhang, Yanjun Qu, Jingjing Duan, Ting Deng, Rui Liu, Le Zhang, Ming Bai, Jialu Li, Likun Zhou, Tao Ning, Hongli Li, Shaohua Ge, Hua Li, Guoguang Ying, Dingzhi Huang, Yi Ba
Pages: 1135-1146
Published online on: 26 November 2015

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Article

Direct binding of Copine3 with Jab1 activates downstream ErbB2 signaling and motility in SKBr3 breast cancer cells

Hye Young Choi, Nammi Park, Jae Boem Na, Eun Sook Ko, Jae-Yong Park, Jae Cheal Yoo
Pages: 1147-1152
Published online on: 02 December 2015

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Article

CX3CL1 increases invasiveness and metastasis by promoting epithelial-to-mesenchymal transition through the TACE/TGF-α/EGFR pathway in hypoxic androgen‑independent prostate cancer cells

Jiebing Tang, Lijie Xiao, Rongjun Cui, Dong Li, Xiulan Zheng, Lijuan Zhu, Hui Sun, Yujia Pan, Yandan Du, Xiaoguang Yu
Pages: 1153-1162
Published online on: 02 December 2015

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Article

Activation of Tax protein by c-Jun-N-terminal kinase is not dependent on the presence or absence of the early growth response-1 gene product

Eduardo Parra, Luís Gutierréz, Jorge Ferreira
Pages: 1163-1169
Published online on: 16 November 2015

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Article

miR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300

Yunhui Hu, Kaiyong Li, Muhammad Asaduzzaman, Raquel Cuella, Hui Shi, Selina Raguz, Raoul Charles Coombes, Yuan Zhou, Ernesto Yagüe
Pages: 1170-1178
Published online on: 12 November 2015

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Article

Expression and purification of recombinant ATF-mellitin, a new type fusion protein targeting ovarian cancer cells, in P. pastoris

Manman Su, Weiqin Chang, Kun Zhang, Manhua Cui, Shuying Wu, Tianmin Xu
Pages: 1179-1185
Published online on: 25 November 2015

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Article

JQ1, an inhibitor of the epigenetic reader BRD4, suppresses the bidirectional MYC-AP4 axis via multiple mechanisms

Sung Kyung Choi, Seong Hwi Hong, Hyuk Soon Kim, Chan Young Shin, Suk Woo Nam, Wahn Soo Choi, Jeung-Whan Han, Jueng Soo You
Pages: 1186-1194
Published online on: 11 November 2015

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Article

RSPH9 methylation pattern as a prognostic indicator in patients with non-muscle invasive bladder cancer

Hyung-Yoon Yoon, Yong-June Kim, Ji Sang Kim, Young-Won Kim, Ho Won Kang, Won Tae Kim, Seok-Joong Yun, Keun Ho Ryu, Sang-Cheol Lee, Wun-Jae Kim
Pages: 1195-1203
Published online on: 11 November 2015

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Article

Tripartite motif 16 suppresses breast cancer stem cell properties through regulation of Gli-1 degradation via the ubiquitin-proteasome pathway Retraction in /10.3892/or.2024.8748

Juntao Yao, Tao Xu, Tao Tian, Xiao Fu, Wenjuan Wang, Suoni Li, Tingting Shi, Aili Suo, Zhiping Ruan, Hui Guo, Yu Yao
Pages: 1204-1212
Published online on: 18 November 2015

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Article

Uvangoletin induces mitochondria-mediated apoptosis in HL-60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances Retraction in /10.3892/or.2025.9015

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Pages: 1213-1221
Published online on: 25 November 2015

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Correction Open Access

[Corrigendum] Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620

Yitao Jia, Suqiao Zhang, Lingling Miao, Jingbao Wang, Zujian Jin, Bin Gu, Zhihui Duan, Zhaolong Zhao, Shunmao Ma, Wenjin Zhang, Zhongxin Li
Pages: 1222-1222
Published online on: 20 November 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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