|
1
|
Jemal A, Siegel R, Xu J and Ward E: Cancer
statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hennessy BT, Coleman RL and Markman M:
Ovarian cancer. Lancet. 374:1371–1382. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Chaffer CL and Weinberg RA: A perspective
on cancer cell metastasis. Science. 331:1559–1564. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Shi Y, Lan F, Matson C, Mulligan P,
Whetstine JR, Cole PA, Casero RA and Shi Y: Histone demethylation
mediated by the nuclear amine oxidase homolog LSD1. Cell.
119:941–953. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Lv T, Yuan D, Miao X, Lv Y, Zhan P, Shen X
and Song Y: Overexpression of LSD1 promotes proliferation,
migration and invasion in non-small cell lung cancer. PLoS One.
7:e350652012. View Article : Google Scholar
|
|
6
|
Hayami S, Kelly JD, Cho HS, Yoshimatsu M,
Unoki M, Tsunoda T, Field HI, Neal DE, Yamaue H, Ponder BA, et al:
Overexpression of LSD1 contributes to human carcinogenesis through
chromatin regulation in various cancers. Int J Cancer. 128:574–586.
2011. View Article : Google Scholar
|
|
7
|
Serce N, Gnatzy A, Steiner S, Lorenzen H,
Kirfel J and Buettner R: Elevated expression of LSD1
(Lysine-specific demethylase 1) during tumour progression from
pre-invasive to invasive ductal carcinoma of the breast. BMC Clin
Pathol. 12:132012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wu CY, Hsieh CY, Huang KE, Chang C and
Kang HY: Cryptotanshinone down-regulates androgen receptor
signaling by modulating lysine-specific demethylase 1 function. Int
J Cancer. 131:1423–1434. 2012. View Article : Google Scholar
|
|
9
|
Kahl P, Gullotti L, Heukamp LC, Wolf S,
Friedrichs N, Vorreuther R, Solleder G, Bastian PJ, Ellinger J,
Metzger E, et al: Androgen receptor coactivators lysine-specific
histone demethylase 1 and four and a half LIM domain protein 2
predict risk of prostate cancer recurrence. Cancer Res.
66:11341–11347. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhao Z-K, Yu H-F, Wang D-R, Dong P, Chen
L, Wu WG, Ding WJ and Liu YB: Overexpression of lysine specific
demethylase 1 predicts worse prognosis in primary hepatocellular
carcinoma patients. World J Gastroenterol. 18:6651–6656. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ding J, Zhang ZM, Xia Y, Liao GQ, Pan Y,
Liu S, Zhang Y and Yan ZS: LSD1-mediated epigenetic modification
contributes to proliferation and metastasis of colon cancer. Br J
Cancer. 109:994–1003. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yu Y, Wang B, Zhang K, Lei Z, Guo Y, Xiao
H, Wang J, Fan L, Lan C, Wei Y, et al: High expression of
lysine-specific demethylase 1 correlates with poor prognosis of
patients with esophageal squamous cell carcinoma. Biochem Biophys
Res Commun. 437:192–198. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Konovalov S and Garcia-Bassets I: Analysis
of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human
ovarian tumors and the effects of chemical LSD1 inhibitors in
ovarian cancer cell lines. J Ovarian Res. 6:752013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen C, Ge J, Lu Q, Ping G, Yang C and
Fang X: Expression of lysine-specific demethylase 1 in human
epithelial ovarian cancer. J Ovarian Res. 8:282015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hay ED: An overview of
epithelio-mesenchymal transformation. Acta Anat (Basel). 154:8–20.
1995. View Article : Google Scholar
|
|
16
|
Boyer B, Vallés AM and Edme N: Induction
and regulation of epithelial-mesenchymal transitions. Biochem
Pharmacol. 60:1091–1099. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Thiery JP: Epithelial-mesenchymal
transitions in tumour progression. Nat Rev Cancer. 2:442–454. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Angst BD, Marcozzi C and Magee AI: The
cadherin superfamily. J Cell Sci. 114:625–626. 2001.PubMed/NCBI
|
|
19
|
Hazan RB, Qiao R, Keren R, Badano I and
Suyama K: Cadherin switch in tumor progression. Ann NY Acad Sci.
1014:155–163. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Perl AK, Wilgenbus P, Dahl U, Semb H and
Christofori G: A causal role for E-cadherin in the transition from
adenoma to carcinoma. Nature. 392:190–193. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Birchmeier W, Hulsken J and Behrens J:
E-cadherin as an invasion suppressor. Ciba Foundation Symposium.
189:124–136; discussion 136–141, 174–126. 1995.PubMed/NCBI
|
|
22
|
Batlle E, Sancho E, Francí C, Domínguez D,
Monfar M, Baulida J and García De Herreros A: The transcription
factor snail is a repressor of E-cadherin gene expression in
epithelial tumour cells. Nat Cell Biol. 2:84–89. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kang Y and Massagué J:
Epithelial-mesenchymal transitions: twist in development and
metastasis. Cell. 118:277–279. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kato Y, Yashiro M, Noda S, Tendo M,
Kashiwagi S, Doi Y, Nishii T, Matsuoka J, Fuyuhiro Y, Shinto O, et
al: Establishment and characterization of a new hypoxia-resistant
cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric
carcinoma. Br J Cancer. 102:898–907. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Yang J, Mani SA, Donaher JL, Ramaswamy S,
Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A and
Weinberg RA: Twist, a master regulator of morphogenesis, plays an
essential role in tumor metastasis. Cell. 117:927–939. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Waldmann J, Feldmann G, Slater EP, Langer
P, Buchholz M, Ramaswamy A, Saeger W, Rothmund M and Fendrich V:
Expression of the zinc-finger transcription factor Snail in
adrenocortical carcinoma is associated with decreased survival. Br
J Cancer. 99:1900–1907. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lin Y, Wu Y, Li J, Dong C, Ye X, Chi YI,
Evers BM and Zhou BP: The SNAG domain of Snail1 functions as a
molecular hook for recruiting lysine-specific demethylase 1. EMBO
J. 29:1803–1816. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lin T, Ponn A, Hu X, Law BK and Lu J:
Requirement of the histone demethylase LSD1 in Snai1-mediated
transcriptional repression during epithelial-mesenchymal
transition. Oncogene. 29:4896–4904. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ferrari-Amorotti G, Fragliasso V, Esteki
R, Prudente Z, Soliera AR, Cattelani S, Manzotti G, Grisendi G,
Dominici M, Pieraccioli M, et al: Inhibiting interactions of lysine
demethylase LSD1 with snail/slug blocks cancer cell invasion.
Cancer Res. 73:235–245. 2013. View Article : Google Scholar :
|
|
30
|
Shao G, Wang J, Li Y, Liu X, Xie X, Wan X,
Yan M, Jin J, Lin Q, Zhu H, et al: Lysine-specific demethylase 1
mediates epidermal growth factor signaling to promote cell
migration in ovarian cancer cells. Sci Rep. 5:153442015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zhang X, Lu F, Wang J, Yin F, Xu Z, Qi D,
Wu X, Cao Y, Liang W, Liu Y, et al: Pluripotent stem cell protein
Sox2 confers sensitivity to LSD1 inhibition in cancer cells. Cell
Reports. 5:445–457. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Shao GB, Wang J, Zhang LP, Wu CY, Jin J,
Sang JR, Lu HY, Gong AH, Du FY and Peng WX: Aging alters histone H3
lysine 4 methylation in mouse germinal vesicle stage oocytes.
Reprod Fertil Dev. 27:419–426. 2015. View
Article : Google Scholar
|
|
33
|
Zhang L, Wang J, Pan Y, Jin J, Sang J,
Huang P and Shao G: Expression of histone H3 lysine 4 methylation
and its demethylases in the developing mouse testis. Cell Tissue
Res. 358:875–883. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li LC, Okino ST, Zhao H, Pookot D, Place
RF, Urakami S, Enokida H and Dahiya R: Small dsRNAs induce
transcriptional activation in human cells. Proc Natl Acad Sci USA.
103:17337–17342. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Ting AH, Schuebel KE, Herman JG and Baylin
SB: Short double-stranded RNA induces transcriptional gene
silencing in human cancer cells in the absence of DNA methylation.
Nat Genet. 37:906–910. 2005. View
Article : Google Scholar : PubMed/NCBI
|
|
36
|
Sun G, Alzayady K, Stewart R, Ye P, Yang
S, Li W and Shi Y: Histone demethylase LSD1 regulates neural stem
cell proliferation. Mol Cell Biol. 30:1997–2005. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Verma M, Seminara D, Arena FJ, John C,
Iwamoto K and Hartmuller V: Genetic and epigenetic biomarkers in
cancer: improving diagnosis, risk assessment, and disease
stratification. Mol Diagn Ther. 10:1–15. 2006. View Article : Google Scholar
|
|
38
|
Seeber LM and van Diest PJ: Epigenetics in
ovarian cancer. Methods Mol Biol. 863:253–269. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
He Y, Korboukh I, Jin J and Huang J:
Targeting protein lysine methylation and demethylation in cancers.
Acta Biochim Biophys Sin (Shanghai). 44:70–79. 2012. View Article : Google Scholar
|
|
40
|
Chen Y, Jie W, Yan W, Zhou K and Xiao Y:
Lysine-specific histone demethylase 1 (LSD1): a potential molecular
target for tumor therapy. Crit Rev Eukaryot Gene Expr. 22:53–59.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Lim S, Janzer A, Becker A, Zimmer A,
Schüle R, Buettner R and Kirfel J: Lysine-specific demethylase 1
(LSD1) is highly expressed in ER-negative breast cancers and a
biomarker predicting aggressive biology. Carcinogenesis.
31:512–520. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Peinado H, Ballestar E, Esteller M and
Cano A: Snail mediates E-cadherin repression by the recruitment of
the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell
Biol. 24:306–319. 2004. View Article : Google Scholar :
|
