Journal Articles
Article
Inhibition of β2-adrenergic receptor reduces triple-negative breast cancer brain metastases: The potential benefit of perioperative β-blockade
Cecilia Choy, John L. Raytis, David D. Smith, Matthew Duenas, Josh Neman, Rahul Jandial, Michael W. Lew
Pages: 3135-3142 Published online on: 28 March 2016
Article
Expression of tropomyosin 2 gene isoforms in human breast cancer cell lines
Syamalima Dube, Anish Thomas, Lynn Abbott, Patricia Benz, Charles Mitschow, Dipak K. Dube, Bernard J. Poiesz
Pages: 3143-3150 Published online on: 04 April 2016
Article
Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo
Magdalena Gabrysiak, Malgorzata Wachowska, Joanna Barankiewicz, Zofia Pilch, Anna Ratajska, Ewa Skrzypek, Magdalena Winiarska, Antoni Domagala, Tomasz P. Rygiel, Alicja Jozkowicz, Louis Boon, Jakub Golab, Malgorzata Firczuk
Pages: 3151-3158 Published online on: 01 April 2016
Article
Enhanced tumor retention of radioiodinated anti-epidermal growth factor receptor antibody using novel bifunctional iodination linker for radioimmunotherapy
Eun Jung Kim, Byoung Soo Kim, Dan Bee Choi, Sung-Gil Chi, Tae Hyun Choi
Pages: 3159-3168 Published online on: 24 March 2016
Article
Variable susceptibility of ovarian cancer cells to non-thermal plasma-activated medium
Fumi Utsumi, Hiroaki Kajiyama, Kae Nakamura, Hiromasa Tanaka, Masaaki Mizuno, Shinnya Toyokuni, Masaru Hori, Fumitaka Kikkawa
Pages: 3169-3177 Published online on: 01 April 2016
Article
Tumor-suppressing roles of miR-214 and miR-218 in breast cancer
Bo Liu, Yanfeng Tian, Fang Li, Zengren Zhao, Xia Jiang, Congjie Zhai, Xiaodong Han, Like Zhang
Pages: 3178-3184 Published online on: 15 April 2016
Article
Characterization of long non-coding RNA expression profiles in lymph node metastasis of early-stage cervical cancer
Chunliang Shang, Wenhui Zhu, Tianyu Liu, Wei Wang, Guangxin Huang, Jiaming Huang, Peizhen Zhao, Yunhe Zhao, Shuzhong Yao
Pages: 3185-3197 Published online on: 29 March 2016
Article
Dual oxidase 1: A predictive tool for the prognosis of hepatocellular carcinoma patients
Shengsen Chen, Qingxia Ling, Kangkang Yu, Chong Huang, Ning Li, Jianming Zheng, Suxia Bao, Qi Cheng, Mengqi Zhu, Mingquan Chen
Pages: 3198-3208 Published online on: 14 April 2016
Article
Aloe-emodin-mediated photodynamic therapy induces autophagy and apoptosis in human osteosarcoma cell line MG‑63 through the ROS/JNK signaling pathway
Pinghua Tu, Qiu Huang, Yunsheng Ou, Xing Du, Kaiting Li, Yong Tao, Hang Yin
Pages: 3209-3215 Published online on: 24 March 2016
Article
Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion
Hiroki Sumiyoshi, Akira Matsushita, Yoshiharu Nakamura, Yoko Matsuda, Toshiyuki Ishiwata, Zenya Naito, Eiji Uchida
Pages: 3216-3226 Published online on: 01 April 2016
Article
Coupling Gd‑DTPA with a bispecific, recombinant protein anti‑EGFR‑iRGD complex improves tumor targeting in MRI
Xiaoyan Xin, Huizi Sha, Jingtao Shen, Bing Zhang, Bin Zhu, Baorui Liu
Pages: 3227-3235 Published online on: 29 March 2016
Article
Malignant, but not benign, intraductal papillary mucinous neoplasm preferentially associates with prior extrapancreatic malignancies
Takaharu Kato, Sergio Alonso, Hiroshi Noda, Yasuyuki Miyakura, Shingo Tsujinaka, Masaaki Saito, Yuta Muto, Taro Fukui, Kosuke Ichida, Yuji Takayama, Fumiaki Watanabe, Nao Kakizawa, Manuel Perucho, Toshiki Rikiyama
Pages: 3236-3240 Published online on: 19 April 2016
Article
Effect of green tea catechins on gastric mucosal dysplasia in insulin-gastrin mice
Takashi Ohno, Masahiro Ohtani, Hiroyuki Suto, Makoto Ohta, Yoshiaki Imamura, Hidetaka Matsuda, Katsushi Hiramatsu, Tomoyuki Nemoto, Yasunari Nakamoto
Pages: 3241-3247 Published online on: 29 March 2016
Article
Gold-conjugated resveratrol nanoparticles attenuate the invasion and MMP-9 and COX-2 expression in breast cancer cells
Sun Young Park, Seon Yeong Chae, Jin Oh Park, Kyu Jin Lee, Geuntae Park
Pages: 3248-3256 Published online on: 29 March 2016
Article
MicroRNA-603 functions as an oncogene by suppressing BRCC2 protein translation in osteosarcoma
Chengbin Ma, Chuan Zhan, Hongmou Yuan, Yan Cui, Zhiyu Zhang
Pages: 3257-3264 Published online on: 30 March 2016
Article
Increased interleukin-6 expression is associated with poor prognosis and acquired cisplatin resistance in head and neck squamous cell carcinoma
Jian Gao, Sen Zhao, Trond S. Halstensen
Pages: 3265-3274 Published online on: 20 April 2016
Article
MicroRNA-205 acts as a tumor suppressor in osteosarcoma via targeting RUNX2 Retraction in /10.3892/or.2021.8106
Can Zhang, Feng Long, Jun Wan, Yihe Hu, Hongbo He
Pages: 3275-3284 Published online on: 23 March 2016
Article
MicroRNA-130a promotes the metastasis and epithelial-mesenchymal transition of osteosarcoma by targeting PTEN
Jiansong Chen, Dingding Yan, Weiliang Wu, Jian Zhu, Wensong Ye, Qiang Shu
Pages: 3285-3292 Published online on: 31 March 2016
Article
CD44hiCD24lo mammosphere-forming cells from primary breast cancer display resistance to multiple chemotherapeutic drugs
Ping Ji, Yong Zhang, Shu-Jun Wang, Hai-Liang Ge, Guo-Ping Zhao, Ying-Chun Xu, Ying Wang
Pages: 3293-3302 Published online on: 11 April 2016
Article
Silencing of ataxia-telangiectasia mutated by siRNA enhances the in vitro and in vivo radiosensitivity of glioma
Yan Li, Luchun Li, Bo Li, Zhijuan Wu, Yongzhong Wu, Ying Wang, Fu Jin, Dairong Li, Huiwen Ma, Donglin Wang
Pages: 3303-3312 Published online on: 19 April 2016
Article
NOB1 silencing inhibits the growth and metastasis of laryngeal cancer cells through the regulation of JNK signaling pathway
Xin Gao, Jin Wang, Weiliang Bai, Wenyue Ji, Liping Wang
Pages: 3313-3320 Published online on: 24 March 2016
Article
Identification of prognostic microRNA candidates for head and neck squamous cell carcinoma
Lian Hui, Hua Wu, Ning Yang, Xing Guo, Xuejun Jang
Pages: 3321-3330 Published online on: 23 March 2016
Article
Effect of Recepteur d'Origine Nantais expression on chemosensitivity and tumor cell behavior in colorectal cancer
Nuri Kim, Sung-Bum Cho, Young-Lan Park, Sun-Young Park, Eun Myung, Seung-Hun Kim, Hyung-Min Yu, Young-Ae Son, Dae-Seong Myung, Wan-Sik Lee, Young-Eun Joo
Pages: 3331-3340 Published online on: 31 March 2016
Article
Oridonin upregulates PTEN through activating p38 MAPK and inhibits proliferation in human colon cancer cells
Qiu-Xiang Wu, Shuang-Xue Yuan, Chun-Mei Ren, Yu Yu, Wen-Juan Sun, Bai-Cheng He, Ke Wu
Pages: 3341-3348 Published online on: 07 April 2016
Article
Whole-exome sequencing identifies a somatic missense mutation of NBN in clear cell sarcoma of the salivary gland
Lei Zhang, Zhen Jia, Fengbiao Mao, Yueyi Shi, Rong Fa Bu, Baorong Zhang
Pages: 3349-3356 Published online on: 08 April 2016
Article
Karyopherin α2 induces apoptosis in tongue squamous cell carcinoma CAL-27 cells through the p53 pathway
Li Gao, Lei Yu, Chun-Ming Li, Ying Li, Bao-Lin Jia, Bin Zhang
Pages: 3357-3362 Published online on: 15 April 2016
Article
Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways
Jiming Liu, Qiang Li, Zhilong Liu, Liuming Lin, Xiangqiang Zhang, Mingrong Cao, Jianwei Jiang
Pages: 3363-3370 Published online on: 21 March 2016
Article
Genome-wide profiling of long non-coding RNA expression patterns in the EGFR-TKI resistance of lung adenocarcinoma by microarray
Ying Wu, Dan-Dan Yu, Yong Hu, Dali Yan, Xiu Chen, Hai‑Xia Cao, Shao-Rong Yu, Zhuo Wang, Ji-Feng Feng
Pages: 3371-3386 Published online on: 20 April 2016
Article
Circadian clock gene Per2 plays an important role in cell proliferation, apoptosis and cell cycle progression in human oral squamous cell carcinoma
Qingqing Wang, Yiran Ao, Kai Yang, Hong Tang, Dan Chen
Pages: 3387-3394 Published online on: 01 April 2016
Article
Nogo-A inhibits the migration and invasion of human malignant glioma U87MG cells
Shu-Guang Jin, Hyang-Hwa Ryu, Song-Yuan Li, Chun-Hao Li, Sa-Hoe Lim, Woo-Youl Jang, Shin Jung
Pages: 3395-3402 Published online on: 08 April 2016
Article
Tumstatin induces apoptosis and stimulates phosphorylation of p65NF-κB in human osteoblastic osteosarcoma Saos-2 cells
Yang Wang, Ruo-Feng Yin, Jia-Song Teng
Pages: 3403-3408 Published online on: 20 April 2016
Article
Lentivirus-mediated knockdown of TSP50 suppresses the growth of non-small cell lung cancer cells via G0/G1 phase arrest
Wen-Liang Qiao, Hai-Yang Hu, Bo-Wen Shi, Li-Juan Zang, Wei Jin, Qiang Lin
Pages: 3409-3418 Published online on: 20 April 2016
Article
S100A4 promotes endometrial cancer progress through epithelial-mesenchymal transition regulation
Teng Hua, Shuangge Liu, Xiaoyan Xin, Liqiong Cai, Rui Shi, Shuqi Chi, Dilu Feng, Hongbo Wang
Pages: 3419-3426 Published online on: 20 April 2016
Article
Mild oxidative stress induced by a low dose of cisplatin contributes to the escape of TRAIL-mediated apoptosis in the ovarian cancer SKOV3 cell line
Jinzhi Lu, Lei Zhang, Fang Xie, Liya Zhu, Xiaolan Li, Jingping Ouyang, Xiaohua He, Song Han, Cunjian Yi
Pages: 3427-3434 Published online on: 23 March 2016
Article
MicroRNA-194 restrains the cell progression of non-small cell lung cancer by targeting human nuclear distribution protein C
Lirong Zhou, Qingguo Di, Baohua Sun, Xiaosheng Wang, Min Li, Jian Shi
Pages: 3435-3444 Published online on: 28 March 2016
Article
h-prune affects anaplastic thyroid cancer invasion and metastasis
Junko Nambu, Tsuyoshi Kobayashi, Masakazu Hashimoto, Hirotaka Tashiro, Keizo Sugino, Fumio Shimamoto, Akira Kikuchi, Hideki Ohdan
Pages: 3445-3452 Published online on: 20 April 2016
Article
miR-100 suppresses the proliferation and tumor growth of esophageal squamous cancer cells via targeting CXCR7
Shao-Mei Zhou, Fang Zhang, Xue-Bin Chen, Cao-Ming Jun, Xin Jing, Deng-Xiong Wei, Yang Xia, Yu-Bai Zhou, Xiang-Qian Xiao, Run-Qing Jia, Jing-Tao Li, Wang Sheng, Yi Zeng
Pages: 3453-3459 Published online on: 23 March 2016
Article
Zoledronic acid increases the antitumor effect of gefitinib treatment for non-small cell lung cancer with EGFR mutations
Chengjun Feng, Xiaoke Liu, Xiaoyu Li, Fuchun Guo, Chuying Huang, Qing Qin, Yongsheng Wang
Pages: 3460-3470 Published online on: 13 April 2016
Article
Inhibition of autophagic flux by ROS promotes apoptosis during DTT-induced ER/oxidative stress in HeLa cells
Xi-Yan Xiang, Xiao-Chun Yang, Jin Su, Jing-Song Kang, Yao Wu, Ya-Nan Xue, Yu-Tong Dong, Lian-Kun Sun
Pages: 3471-3479 Published online on: 01 April 2016
Article
A novel cell cycle blocker extracted from Stellera chamaejasme L. inhibits the proliferation of hepatocarcinoma cells
Xiao-Xi Kan, Qi Li, Xi Chen, Ya-Jie Wang, Yu-Jie Li, Qing Yang, Hong-Bin Xiao, Zhi-Xin Wang, Ying Chen, Xiao-Gang Weng, Wei-Yan Cai, Xiao-Xin Zhu
Pages: 3480-3488 Published online on: 13 April 2016
Article
EFEMP1 inhibits migration of hepatocellular carcinoma by regulating MMP2 and MMP9 via ERK1/2 activity
Cheng-Yun Dou, Chuang-Jie Cao, Zhuo Wang, Ru-Hua Zhang, Lei‑Lei Huang, Jia-Yan Lian, Wen-Lin Xie, Lian-Tang Wang
Pages: 3489-3495 Published online on: 05 April 2016
Article
Stromal interaction molecule 1 plays an important role in gastric cancer progression
Jin-Mei Xu, Yan Zhou, Long Gao, Shu-Xian Zhou, Wei-Hua Liu, Xiao-An Li
Pages: 3496-3504 Published online on: 24 March 2016
Article
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways
Ke Ma, Chuying Wang, Qianqian Geng, Yangwei Fan, Jing Ning, Haixia Yang, Xuyuan Dong, Danfeng Dong, Yuyan Guo, Xin Wei, Enxiao Li, Yinying Wu
Pages: 3505-3513 Published online on: 28 March 2016
Article
n-3 polyunsaturated fatty acids abrogate mTORC1/2 signaling and inhibit adrenocortical carcinoma growth in vitro and in vivo
Jun Liu, Meinian Xu, Yongbin Zhao, Chunping Ao, Yukun Wu, Zhenguo Chen, Bangqi Wang, Xiaochun Bai, Ming Li, Weilie Hu
Pages: 3514-3522 Published online on: 31 March 2016
Article
mir-1-mediated paracrine effect of cancer-associated fibroblasts on lung cancer cell proliferation and chemoresistance
Jianmin Li, Jing Guan, Xiaoping Long, Yang Wang, Xudong Xiang
Pages: 3523-3531 Published online on: 29 March 2016
Article
Miz-1 promotes the proliferation of esophageal cancer cells via suppression of p21 and release of p21-arrested cyclin D1
Jun Luo, Cheng Zhang, Congyi Wang, Linjun Li, Chunhong Li, Qiang Li, Min Zhang, Qingchen Wu
Pages: 3532-3540 Published online on: 04 April 2016
Article
miR-491-5p suppresses cell growth and invasion by targeting Notch3 in nasopharyngeal carcinoma
Qi Zhang, Qiang Li, Tao Xu, Hui Jiang, Lin-Gen Xu
Pages: 3541-3547 Published online on: 29 March 2016
Article
Prediction of key genes in ovarian cancer treated with decitabine based on network strategy
Yu-Zhen Wang, Sheng-Chun Qiu
Pages: 3548-3558 Published online on: 23 March 2016
Article
Radiation-induced autophagy promotes esophageal squamous cell carcinoma cell survival via the LKB1 pathway
Chi Lu, Conghua Xie
Pages: 3559-3565 Published online on: 19 April 2016
Article
SPOCK1 promotes the proliferation, migration and invasion of glioma cells through PI3K/AKT and Wnt/β-catenin signaling pathways
Jinghui Yang, Qiwei Yang, Jing Yu, Ximeng Li, Shan Yu, Xuewen Zhang
Pages: 3566-3576 Published online on: 20 April 2016
Article
HOTTIP and HOXA13 are oncogenes associated with gastric cancer progression
Shuai Chang, Junsong Liu, Shaochun Guo, Shicai He, Guanglin Qiu, Jing Lu, Jin Wang, Lin Fan, Wei Zhao, Xiangming Che
Pages: 3577-3585 Published online on: 13 April 2016
Article
LSD1-mediated epigenetic modification contributes to ovarian cancer cell migration and invasion
Yuanxia Li, Xiaolei Wan, Ye Wei, Xiuwen Liu, Wensheng Lai, Liuping Zhang, Jie Jin, Chaoyang Wu, Qixiang Shao, Genbao Shao, Qiong Lin
Pages: 3586-3592 Published online on: 04 April 2016
Article
Inhibition of the Ras-ERK pathway in mitotic COS7 cells is due to the inability of EGFR/Raf to transduce EGF signaling to downstream proteins
Huaiping Shi, Tianying Zhang, Yongqing Yi, Yue Ma
Pages: 3593-3599 Published online on: 21 March 2016
Article
Improved antitumor activity and reduced myocardial toxicity of doxorubicin encapsulated in MPEG-PCL nanoparticles
Chuntang Sun, Le Zhou, Maling Gou, Shuai Shi, Tao Li, Jinyi Lang
Pages: 3600-3606 Published online on: 15 April 2016
Article
FOXQ1 promotes gastric cancer metastasis through upregulation of Snail
Jing Zhang, Yimin Liu, Jia Zhang, Xiaohai Cui, Gang Li, Jiansheng Wang, Hong Ren, Yunfeng Zhang
Pages: 3607-3613 Published online on: 08 April 2016
Article
Meloxicam suppresses hepatocellular carcinoma cell proliferation and migration by targeting COX-2/PGE2-regulated activation of the β-catenin signaling pathway
Tao Li, Jingtao Zhong, Xiaofeng Dong, Peng Xiu, Fuhai Wang, Honglong Wei, Xin Wang, Zongzhen Xu, Feng Liu, Xueying Sun, Jie Li
Pages: 3614-3622 Published online on: 20 April 2016
Article
Tumor metastatic promoter ABCE1 interacts with the cytoskeleton protein actin and increases cell motility
Xu Han, Ye Tian, Dali Tian
Pages: 3623-3629 Published online on: 19 April 2016
Article
NF-YA promotes invasion and angiogenesis by upregulating EZH2-STAT3 signaling in human melanoma cells
Zihan Xu, Yaowen Sun, Yadong Guo, Gaoping Qin, Shengzhi Mu, Ronghui Fan, Benfeng Wang, Wenjie Gao, Hangli Wu, Guodong Wang, Zhenxin Zhang
Pages: 3630-3638 Published online on: 20 April 2016
Article
Radiation induces autophagic cell death via the p53/DRAM signaling pathway in breast cancer cells
Li Cui, Zhiheng Song, Bing Liang, Lili Jia, Shumei Ma, Xiaodong Liu
Pages: 3639-3647 Published online on: 19 April 2016
Article
Diallyl trisulfide induces osteosarcoma cell apoptosis through reactive oxygen species-mediated downregulation of the PI3K/Akt pathway
Hongliang Wang, Na Sun, Xin Li, Ka Li, Jiguang Tian, Jianmin Li
Pages: 3648-3658 Published online on: 01 April 2016
Article
Osthole shows the potential to overcome P-glycoprotein‑mediated multidrug resistance in human myelogenous leukemia K562/ADM cells by inhibiting the PI3K/Akt signaling pathway
Hong Wang, Xiu-Hong Jia, Jie-Ru Chen, Jian-Yong Wang, You-Jie Li
Pages: 3659-3668 Published online on: 04 April 2016
Article
Radiosensitization of esophageal carcinoma cells by the silencing of BMI-1
Xing-Xiao Yang, Mei-Xiang Sang, Shu-Chai Zhu, Zhi-Kun Liu, Ming Ma
Pages: 3669-3678 Published online on: 13 April 2016
Article
ETS transcription factor ERG cooperates with histone demethylase KDM4A
Tae-Dong Kim, Sook Shin, Ralf Janknecht
Pages: 3679-3688 Published online on: 15 April 2016
Article
Oncogene-mediated tumor transformation sensitizes cells to autophagy induction
Ricardo Gargini, Vega García-Escudero, Marta Izquierdo, Francisco Wandosell
Pages: 3689-3695 Published online on: 23 March 2016
Article
Resveratrol inhibits cell cycle progression by targeting Aurora kinase A and Polo-like kinase 1 in breast cancer cells
Rubiceli Medina-Aguilar, Laurence A. Marchat, Elena Arechaga Ocampo, Patricio Gariglio, Jaime García Mena, Nicolás Villegas Sepúlveda, Macario Martínez Castillo, César López-Camarillo
Pages: 3696-3704 Published online on: 04 April 2016
Article
MAP30 inhibits autophagy through enhancing acetyltransferase p300 and induces apoptosis in acute myeloid leukemia cells
Shanhu Qian, Lan Sun, Jiaqi Li, Junqing Wu, Gang Hu, Yixiang Han, Kang Yu, Shenghui Zhang
Pages: 3705-3713 Published online on: 24 March 2016
Article
Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, angiopoiesis and migration effects via activating HSP90 pathway in EC109 cells
Yiyan Lei, Yulan Zhen, Wei Zhang, Xiuting Sun, Xiaoxiong Lin, Jianqiang Feng, Honghe Luo, Zhenguang Chen, Chunhua Su, Bo Zeng, Jingfu Chen
Pages: 3714-3720 Published online on: 05 April 2016
Article
Suppression of SOX18 by siRNA inhibits cell growth and invasion of breast cancer cells
Jianxiang Zhang, Yanmei Ma, Shoujun Wang, Fu Chen, Yuanting Gu
Pages: 3721-3727 Published online on: 15 April 2016
Article
Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway
Lei Cao, Xue Xiao, Jianjun Lei, Wanxing Duan, Qingyong Ma, Wei Li
Pages: 3728-3734 Published online on: 28 March 2016
Article
Combined metformin and resveratrol confers protection against UVC-induced DNA damage in A549 lung cancer cells via modulation of cell cycle checkpoints and DNA repair
Yong-Syu Lee, Barbara B. Doonan, Joseph M. Wu, Tze-Chen Hsieh
Pages: 3735-3741 Published online on: 11 April 2016
Article
