|
1
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2013. CA Cancer J Clin. 63:11–30. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Vaupel P and Mayer A: Hypoxia in cancer:
Significance and impact on clinical outcome. Cancer Metastasis Rev.
26:225–239. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Semenza GL: Targeting HIF-1 for cancer
therapy. Nat Rev Cancer. 3:721–732. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kalluri R and Weinberg RA: The basics of
epithelial-mesenchymal transition. J Clin Invest. 119:1420–1428.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cannito S, Novo E, Compagnone A, Valfrè di
Bonzo L, Busletta C, Zamara E, Paternostro C, Povero D, Bandino A,
Bozzo F, et al: Redox mechanisms switch on hypoxia-dependent
epithelial-mesenchymal transition in cancer cells. Carcinogenesis.
29:2267–2278. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Peinado H, Olmeda D and Cano A: Snail, Zeb
and bHLH factors in tumour progression: An alliance against the
epithelial phenotype? Nat Rev Cancer. 7:415–428. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Imai T, Horiuchi A, Wang C, Oka K, Ohira
S, Nikaido T and Konishi I: Hypoxia attenuates the expression of
E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells.
Am J Pathol. 163:1437–1447. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang
SY, Liu CJ, Teng SC and Wu KJ: Direct regulation of TWIST by
HIF-1alpha promotes metastasis. Nat Cell Biol. 10:295–305. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Cheng ZX, Sun B, Wang SJ, Gao Y, Zhang YM,
Zhou HX, Jia G, Wang YW, Kong R, Pan SH, et al: Nuclear
factor-κB-dependent epithelial to mesenchymal transition induced by
HIF-1α activation in pancreatic cancer cells under hypoxic
conditions. PLoS One. 6:e237522011. View Article : Google Scholar
|
|
10
|
Grünert S, Jechlinger M and Beug H:
Diverse cellular and molecular mechanisms contribute to epithelial
plasticity and metastasis. Nat Rev Mol Cell Biol. 4:657–665. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Huber MA, Kraut N and Beug H: Molecular
requirements for epithelial-mesenchymal transition during tumor
progression. Curr Opin Cell Biol. 17:548–558. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Min C, Eddy SF, Sherr DH and Sonenshein
GE: NF-kappaB and epithelial to mesenchymal transition of cancer. J
Cell Biochem. 104:733–744. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Shin SR, Sánchez-Velar N, Sherr DH and
Sonenshein GE: 7,12-dimethylbenz(a)anthracene treatment of a c-rel
mouse mammary tumor cell line induces epithelial to mesenchymal
transition via activation of nuclear factor-kappaB. Cancer Res.
66:2570–2575. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Harris AL: Hypoxia - a key regulatory
factor in tumour growth. Nat Rev Cancer. 2:38–47. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Semenza GL: Defining the role of
hypoxia-inducible factor 1 in cancer biology and therapeutics.
Oncogene. 29:625–634. 2010. View Article : Google Scholar :
|
|
16
|
Le QT, Denko NC and Giaccia AJ: Hypoxic
gene expression and metastasis. Cancer Metastasis Rev. 23:293–310.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Movsas B, Chapman JD, Greenberg RE, Hanlon
AL, Horwitz EM, Pinover WH, Stobbe C and Hanks GE: Increasing
levels of hypoxia in prostate carcinoma correlate significantly
with increasing clinical stage and patient age: An Eppendorf
pO2 study. Cancer. 89:2018–2024. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Jiang YG, Luo Y, He DL, Li X, Zhang LL,
Peng T, Li MC and Lin YH: Role of Wnt/beta-catenin signaling
pathway in epithelial-mesenchymal transition of human prostate
cancer induced by hypoxia-inducible factor-1alpha. Int J Urol.
14:1034–1039. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhao JH, Luo Y, Jiang YG, He DL and Wu CT:
Knockdown of β-Catenin through shRNA cause a reversal of EMT and
metastatic phenotypes induced by HIF-1α. Cancer Invest. 29:377–382.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhao L, Jiang YG, Ma J, Luo Y and Zhao JH:
Characterization of prostate cancer cell lines and their
epithelial-mesenchymal transition in subcutaneous tumors. Zhonghua
Nan Ke Xue. 17:314–317. 2011.In Chinese. PubMed/NCBI
|
|
21
|
Hugo H, Ackland ML, Blick T, Lawrence MG,
Clements JA, Williams ED and Thompson EW: Epithelial-mesenchymal
and mesenchymal-epithelial transitions in carcinoma progression. J
Cell Physiol. 213:374–383. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Thomas R and Kim MH: HIF-1 alpha: A key
survival factor for serum-deprived prostate cancer cells. Prostate.
68:1405–1415. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhong H, Agani F, Baccala AA, Laughner E,
Rioseco-Camacho N, Isaacs WB, Simons JW and Semenza GL: Increased
expression of hypoxia inducible factor-1alpha in rat and human
prostate cancer. Cancer Res. 58:5280–5284. 1998.PubMed/NCBI
|
|
24
|
Luo Y, He DL, Ning L, Shen SL, Li L, Li X,
Zhau HE and Chung LW: Over-expression of hypoxia-inducible
factor-1alpha increases the invasive potency of LNCaP cells in
vitro. BJU Int. 98:1315–1319. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Krishnamachary B, Berg-Dixon S, Kelly B,
Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi
P, et al: Regulation of colon carcinoma cell invasion by
hypoxia-inducible factor 1. Cancer Res. 63:1138–1143.
2003.PubMed/NCBI
|
|
26
|
Du R, Huang C, Bi Q, Zhai Y, Xia L, Liu J,
Sun S and Fan D: URG11 mediates hypoxia-induced
epithelial-to-mesenchymal transition by modulation of E-cadherin
and beta-catenin. Biochem Biophys Res Commun. 391:135–141. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhou BP, Deng J, Xia W, Xu J, Li YM,
Gunduz M and Hung MC: Dual regulation of Snail by
GSK-3beta-mediated phosphorylation in control of
epithelial-mesenchymal transition. Nat Cell Biol. 6:931–940. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Yates CC, Shepard CR, Stolz DB and Wells
A: Co-culturing human prostate carcinoma cells with hepatocytes
leads to increased expression of E-cadherin. Br J Cancer.
96:1246–1252. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yates C, Shepard CR, Papworth G, Dash A,
Beer Stolz D, Tannenbaum S, Griffith L and Wells A: Novel
three-dimensional organotypic liver bioreactor to directly
visualize early events in metastatic progression. Adv Cancer Res.
97:225–246. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
van der Pluijm G: Epithelial plasticity,
cancer stem cells and bone metastasis formation. Bone. 48:37–43.
2011. View Article : Google Scholar
|
|
31
|
Chaffer CL, Brennan JP, Slavin JL, Blick
T, Thompson EW and Williams ED: Mesenchymal-to-epithelial
transition facilitates bladder cancer metastasis: Role of
fibroblast growth factor receptor-2. Cancer Res. 66:11271–11278.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Elloul S, Vaksman O, Stavnes HT, Trope CG,
Davidson B and Reich R: Mesenchymal-to-epithelial transition
determinants as characteristics of ovarian carcinoma effusions.
Clin Exp Metastasis. 27:161–172. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Moen I, Øyan AM, Kalland KH, Tronstad KJ,
Akslen LA, Chekenya M, Sakariassen PO, Reed RK and Stuhr LE:
Hyperoxic treatment induces mesenchymal-to-epithelial transition in
a rat adenocarcinoma model. PLoS One. 4:e63812009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Hill RP, Marie-Egyptienne DT and Hedley
DW: Cancer stem cells, hypoxia and metastasis. Semin Radiat Oncol.
19:106–111. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Phinney DG: Twist,
epithelial-to-mesenchymal transition, and stem cells. Stem Cells.
29:3–4. 2010. View
Article : Google Scholar
|
|
36
|
Martin A and Cano A: Tumorigenesis: Twist1
links EMT to self-renewal. Nat Cell Biol. 12:924–925. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zavadil J: A spotlight on regulatory
networks connecting EMT and cancer stem cells. Cell Cycle.
9:2927–2935. 2010. View Article : Google Scholar : PubMed/NCBI
|
