Journal Articles
Review
The role of JAM-B in cancer and cancer metastasis (Review)
Huishan Zhao, Hefen Yu, Tracey A. Martin, Xu Teng, Wen G. Jiang
Pages: 3-9 Published online on: 27 April 2016
Article
Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma
Song Xu, Xiao-Ming Yi, Chao-Peng Tang, Jing-Ping Ge, Zheng-Yu Zhang, Wen-Quan Zhou
Pages: 10-22 Published online on: 09 May 2016
Article
Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway
Ying Zhang, Lianjie Lin, Yu Jin, Yan Lin, Yong Cao, Changqing Zheng
Pages: 23-30 Published online on: 27 April 2016
Article
Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells
Hye-Sook Seo, Jin Mo Ku, Han-Seok Choi, Youn Kyung Choi, Jong-Kyu Woo, Minsoo Kim, Ilhwan Kim, Chang Hyeok Na, Hansol Hur, Bo‑Hyoung Jang, Yong Cheol Shin, Seong-Gyu Ko
Pages: 31-42 Published online on: 05 May 2016
Article
Low expression of leptin and its association with breast cancer: A transcriptomic study
Sajjad Karim, Adnan Merdad, Hans-Juergen Schulten, Manikandan Jayapal, Ashraf Dallol, Abdelbaset Buhmeida, Fatima Al-Thubaity, Zeenat Mirza, Mamdooh A. Gari, Adeel G. Chaudhary, Adel M. Abuzenadah, Mohammed H. Al-Qahtani
Pages: 43-48 Published online on: 13 May 2016
Article
Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1
Yonghuan Mao, Ling Xi, Quan Li, Zeling Cai, Yimei Lai, Xinhua Zhang, Chunzhao Yu
Pages: 49-56 Published online on: 18 May 2016
Article
Methylation-induced silencing of maspin contributes to the proliferation of human glioma cells
Liang Xu, Hongyuan Liu, Ju Yu, Zhongyong Wang, Qing Zhu, Zongping Li, Qi Zhong, Shuyu Zhang, Mingqi Qu, Qing Lan
Pages: 57-64 Published online on: 04 May 2016
Article
miR-136 suppresses tumor invasion and metastasis by targeting RASAL2 in triple-negative breast cancer
Meisi Yan, Xiaobo Li, Dandan Tong, Changsong Han, Ran Zhao, Yan He, Xiaoming Jin
Pages: 65-71 Published online on: 25 April 2016
Article
Ionizing radiation promotes advanced malignant traits in nasopharyngeal carcinoma via activation of epithelial-mesenchymal transition and the cancer stem cell phenotype
Zhongwu Su, Guo Li, Chao Liu, Shuling Ren, Yongquan Tian, Yong Liu, Yuanzheng Qiu
Pages: 72-78 Published online on: 25 April 2016
Article
A new non-muscle-invasive bladder tumor-homing peptide identified by phage display in vivo
Xiaofeng Yang, Fan Zhang, Junqian Luo, Jianzhi Pang, Sanhua Yan, Fang Luo, Jiehao Liu, Wei Wang, Yongping Cui, Xixi Su
Pages: 79-89 Published online on: 23 May 2016
Article
Cinobufagin induces autophagy-mediated cell death in human osteosarcoma U2OS cells through the ROS/JNK/p38 signaling pathway
Kun Ma, Chuan Zhang, Man-Yu Huang, Wu-Yin Li, Guo-Qiang Hu
Pages: 90-98 Published online on: 28 April 2016
Article
Polyphenols from Korean prostrate spurge Euphorbia supina induce apoptosis through the Fas-associated extrinsic pathway and activation of ERK in human leukemic U937 cells
Min-Ho Han, Won Sup Lee, Arulkumar Nagappan, Hye Jung Kim, Cheol Park, Gi-Young Kim, Sang Hoon Hong, Nam Deuk Kim, Gonsup Kim, Chung Ho Ryu, Sung Chul Shin, Yung Hyun Choi
Pages: 99-107 Published online on: 28 April 2016
Article
STAT3 regulates hypoxia-induced epithelial mesenchymal transition in oesophageal squamous cell cancer
Yao Cui, Yun-Yun Li, Jian Li, Hong-Yan Zhang, Feng Wang, Xue Bai, Shan-Shan Li
Pages: 108-116 Published online on: 19 May 2016
Article
Manumycin A induces apoptosis in malignant pleural mesothelioma through regulation of Sp1 and activation of the mitochondria-related apoptotic pathway
Ka Hwi Kim, Jung-Il Chae, Hana Oh, Jin Hyoung Cho, Ra-Ham Lee, Goo Yoon, Seung-Sik Cho, Young-Sik Cho, Mee-Hyun Lee, Kangdong Liu, Hyun-Jeong Lee, Jung-Hyun Shim
Pages: 117-124 Published online on: 10 May 2016
Article
Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer
Giovanni Luca Gravina, Francesco Marampon, Patrizia Sanità, Andrea Mancini, Alessandro Colapietro, Luca Scarsella, Ana Jitariuc, Leda Biordi, Corrado Ficorella, Claudio Festuccia
Pages: 125-130 Published online on: 23 May 2016
Article
Development of a novel microbubble-liposome complex conjugated with peptide ligands targeting IL4R on brain tumor cells
See-Hyoung Park, Young II Yoon, Hyoungwon Moon, Ga-Hyun Lee, Byung-Heon Lee, Tae-Jong Yoon, Hak Jong Lee
Pages: 131-136 Published online on: 24 May 2016
Article
20(S)-ginsenoside Rh2 inhibits the proliferation and induces the apoptosis of KG-1a cells through the Wnt/β-catenin signaling pathway
Yi Chen, Ze-Hong Liu, Jing Xia, Xiao-Peng Li, Ke‑Qiong Li, Wei Xiong, Jing Li, Di-Long Chen
Pages: 137-146 Published online on: 27 April 2016
Article
Safflower polysaccharide induces NSCLC cell apoptosis by inhibition of the Akt pathway
Jian-Ying Li, Jun Yu, Xu-Sheng Du, Hui-Min Zhang, Bo Wang, Hua Guo, Jie Bai, Juan-Hong Wang, An Liu, Yi-Li Wang
Pages: 147-154 Published online on: 04 May 2016
Article
Genome-wide analysis of the effect of esophageal squamous cell carcinoma on human umbilical vein endothelial cells
Guoguo Jin, Yi Yang, Hangfan Liu, Kangdong Liu, Jimin Zhao, Xinhuan Chen, Xiaoyan Zhang, Yanyan Zhang, Jing Lu, Ziming Dong
Pages: 155-164 Published online on: 18 May 2016
Article
Isoquercitrin inhibits bladder cancer progression in vivo and in vitro by regulating the PI3K/Akt and PKC signaling pathways Retraction in /10.3892/or.2023.8684
Feng Chen, Xiaochi Chen, Deyong Yang, Xiangyu Che, Jianbo Wang, Xiancheng Li, Zhiwei Zhang, Qifei Wang, Wei Zheng, Lina Wang, Xuejian Wang, Xishuang Song
Pages: 165-172 Published online on: 09 May 2016
Article
RNaseH2A is involved in human gliomagenesis through the regulation of cell proliferation and apoptosis
Bin Dai, Peng Zhang, Yisong Zhang, Changcun Pan, Guolu Meng, Xinru Xiao, Zhen Wu, Wang Jia, Junting Zhang, Liwei Zhang
Pages: 173-180 Published online on: 10 May 2016
Article
Notch2 is a crucial regulator of self-renewal and tumorigenicity in human hepatocellular carcinoma cells
Wen-Rui Wu, Rui Zhang, Xiang-De Shi, Cao Yi, Lei-Bo Xu, Chao Liu
Pages: 181-188 Published online on: 23 May 2016
Article
MicroRNA-146a inhibits cell migration and invasion by targeting RhoA in breast cancer
Qin Liu, Wei Wang, Xiongfa Yang, Dongxiao Zhao, Fangqiong Li, Hai Wang
Pages: 189-196 Published online on: 06 May 2016
Article
Nuclear EpICD expression and its role in hepatocellular carcinoma
Shin Young Park, Jun Sang Bae, Eun Jung Cha, Hyun Hee Chu, Jang Sihn Sohn, Woo Sung Moon
Pages: 197-204 Published online on: 06 May 2016
Article
Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway Corrigendum in /10.3892/or.2022.8301
Moon Hee Lee, Su-Hyun Hong, Cheol Park, Gi-Young Kim, Sun-Hee Leem, Sung Hyun Choi, Young-Sam Keum, Jin Won Hyun, Taeg Kyu Kwon, Sang Hoon Hong, Yung Hyun Choi
Pages: 205-214 Published online on: 17 May 2016
Article
An eight-long non-coding RNA signature as a candidate prognostic biomarker for lung cancer
Zhenbo Tu, Du He, Xinzhou Deng, Meng Xiong, Xiaoxing Huang, Xinran Li, Ling Hao, Qianshan Ding, Qiuping Zhang
Pages: 215-222 Published online on: 18 May 2016
Article
Knockdown of DDX46 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma cells
Bin Li, Yu-Min Li, Wen-Ting He, Hao Chen, Hong-Wen Zhu, Tao Liu, Jian-Hua Zhang, Tie-Niu Song, Ya-Li Zhou
Pages: 223-230 Published online on: 11 May 2016
Article
B7-H3 upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu
Zhang Zhang Sun, Ting Zhang, Kuan Ning, Ruan Zhu, Fen Liu, Shou-Ching Tang, Bo Jiang, Dong Hua
Pages: 231-238 Published online on: 13 May 2016
Article
Zidovudine, abacavir and lamivudine increase the radiosensitivity of human esophageal squamous cancer cell lines
Xuan Chen, Cong Wang, Shanghui Guan, Yuan Liu, Lihui Han, Yufeng Cheng
Pages: 239-246 Published online on: 18 May 2016
Article
Downregulation of miR-377 contributes to IRX3 deregulation in hepatocellular carcinoma
Pei Wang, Chunbo Zhuang, Da Huang, Keshu Xu
Pages: 247-252 Published online on: 18 May 2016
Article
Lunasin suppresses the migration and invasion of breast cancer cells by inhibiting matrix metalloproteinase-2/-9 via the FAK/Akt/ERK and NF-κB signaling pathways
Qianqian Jiang, Yu Pan, Yupeng Cheng, Huiling Li, Dandan Liu, Hui Li
Pages: 253-262 Published online on: 09 May 2016
Article
Silencing of long non-coding RNA ANRIL inhibits the development of multidrug resistance in gastric cancer cells
Wei-Guang Lan, Dian-Hong Xu, Chen Xu, Chang-Ling Ding, Fang-Ling Ning, Yan-Li Zhou, Long-Bo Ma, Chang-Min Liu, Xia Han
Pages: 263-270 Published online on: 26 April 2016
Article
Ferulic acid exerts antitumor activity and inhibits metastasis in breast cancer cells by regulating epithelial to mesenchymal transition
Xiang Zhang, Dan Lin, Rong Jiang, Hongzhong Li, Jingyuan Wan, Hongyuan Li
Pages: 271-278 Published online on: 12 May 2016
Article
S100A8 facilitates the migration of colorectal cancer cells through regulating macrophages in the inflammatory microenvironment
He Zha, Hui Sun, Xueru Li, Liang Duan, Aifang Li, Yue Gu, Zongyue Zeng, Jiali Zhao, Jiaqing Xie, Shimei Yuan, Huan Li, Lan Zhou
Pages: 279-290 Published online on: 06 May 2016
Article
Oxymatrine inhibits the proliferation of CaSki cells via downregulating HPV16E7 expression
Zhijun Pei, Jing Zeng, Yan Gao, Fuyan Li, Wei Li, Hong Zhou, Yi Yang, Ruimin Wu, Yijia Chen, Jie Liu
Pages: 291-298 Published online on: 10 May 2016
Article
Effects of TMEM9 gene on cell progression in hepatocellular carcinoma by RNA interference
Yi Zhang, Yan Ran, Yan Xiong, Zi-Biao Zhong, Zheng‑Hua Wang, Xiao-Li Fan, Qi-Fa Ye
Pages: 299-305 Published online on: 19 May 2016
Article
T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12
Zongmiao Wan, Dongjie Jiang, Su Chen, Jian Jiao, Lei Ji, Abdus Saboor Shah, Haifeng Wei, Xinghai Yang, Xiaotao Li, Ying Wang, Jianru Xiao
Pages: 306-314 Published online on: 09 May 2016
Article
Lentinan mitigates therarubicin-induced myelosuppression by activating bone marrow-derived macrophages in an MAPK/NF-κB-dependent manner
Qiang Liu, Lei Dong, Hong Li, Jia Yuan, Yuping Peng, Shejiao Dai
Pages: 315-323 Published online on: 26 April 2016
Article
Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma through the induction of apoptosis, cell cycle arrest, mitochondrial membrane potential loss and inhibition of cell migration and invasion Retraction in /10.3892/or.2021.8058
Hui-Juan Wu, Hong-Bo Wu, Yan-Qiu Zhao, Li-Juan Chen, Hong-Zhi Zou
Pages: 324-332 Published online on: 23 May 2016
Article
A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP
Hui Liu, Feihu Chen, Ling Zhang, Qing Zhou, Shuyu Gui, Yuan Wang
Pages: 333-341 Published online on: 09 May 2016
Article
Myricetin suppresses p21-activated kinase 1 in human breast cancer MCF-7 cells through downstream signaling of the β-catenin pathway
De Jiao, Xue Dong Zhang
Pages: 342-348 Published online on: 28 April 2016
Article
Induction of KIFC1 expression in gastric cancer spheroids
Naohide Oue, Shoichiro Mukai, Takeharu Imai, Trang T.B. Pham, Takashi Oshima, Kazuhiro Sentani, Naoya Sakamoto, Kazuhiro Yoshida, Wataru Yasui
Pages: 349-355 Published online on: 28 April 2016
Article
The combination of NVP-BKM120 with trastuzumab or RAD001 synergistically inhibits the growth of breast cancer stem cells in vivo
Feng Yu, Jing Zhao, Yunhui Hu, Yang Zhou, Rong Guo, Jingchao Bai, Sheng Zhang, Huilai Zhang, Jin Zhang
Pages: 356-364 Published online on: 10 May 2016
Article
Combined use of PI3K and MEK inhibitors synergistically inhibits lung cancer with EGFR and KRAS mutations
Ze-Bo Jiang, Jun Huang, Chun Xie, Xia Li, Liping Liu, Jiaxi He, Hui Pan, Liyan Huang, Xing-Xing Fan, Xiao-Jun Yao, Ying Xie, Na Li, Liang Liu, Jian-Xing He, Elaine Lai-Han Leung
Pages: 365-375 Published online on: 26 April 2016
Article
Downregulation of miR-195 promotes prostate cancer progression by targeting HMGA1
Xiaowen Zhang, Tao Tao, Chunhui Liu, Han Guan, Yeqing Huang, Bin Xu, Ming Chen
Pages: 376-382 Published online on: 09 May 2016
Article
Protocadherin-10 acts as a tumor suppressor gene, and is frequently downregulated by promoter methylation in pancreatic cancer cells
Chan Qiu, Xiaona Bu, Zheng Jiang
Pages: 383-389 Published online on: 09 May 2016
Article
Downregulation of miR-34a contributes to the proliferation and migration of laryngeal carcinoma cells by targeting cyclin D1
Jin Ye, Laisheng Li, Pinning Feng, Jianxin Wan, Jingjia Li
Pages: 390-398 Published online on: 19 May 2016
Article
Improved safety and efficacy of a lipid emulsion loaded with a paclitaxel-cholesterol complex for the treatment of breast tumors
Jun Ye, Yuling Liu, Xuejun Xia, Luhua Meng, Wujun Dong, Renyun Wang, Zhaodi Fu, Hongyan Liu, Rui Han
Pages: 399-409 Published online on: 06 May 2016
Article
BMP9 inhibits the growth and migration of lung adenocarcinoma A549 cells in a bone marrow stromal cell‑derived microenvironment through the MAPK/ERK and NF-κB pathways
Jing Wang, Yaguang Weng, Minghao Zhang, Ya Li, Mengtian Fan, Yangliu Guo, Yanting Sun, Wang Li, Qiong Shi
Pages: 410-418 Published online on: 09 May 2016
Article
Aberrant expression of B7-H4 correlates with poor prognosis and suppresses tumor-infiltration of CD8+ T lymphocytes in human cholangiocarcinoma
Xin Zhao, Fei Guo, Zhonghu Li, Peng Jiang, Xiang Deng, Feng Tian, Xiaowu Li, Shuguang Wang
Pages: 419-427 Published online on: 13 May 2016
Article
Ursolic acid inhibits proliferation and reverses drug resistance of ovarian cancer stem cells by downregulating ABCG2 through suppressing the expression of hypoxia-inducible factor-1α in vitro
Wen-Jing Wang, Hua Sui, Cong Qi, Qi Li, Jie Zhang, Shao-Fei Wu, Ming-Zhu Mei, Ying-Yu Lu, Yi-Ting Wan, Hannah Chang, Piao-Ting Guo
Pages: 428-440 Published online on: 18 May 2016
Article
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells
Jia Wang, Xianyao Wan, Yifan Gao, Mintao Zhong, Li Sha, Ben Liu, Wei Zhang, Li Tian, Wenjing Ruan, Shuyun Cao, Min Huang
Pages: 441-447 Published online on: 23 May 2016
Article
Tspan9 inhibits the proliferation, migration and invasion of human gastric cancer SGC7901 cells via the ERK1/2 pathway
Pai-Yun Li, Jing Lv, Wei-Wei Qi, Shu-Fen Zhao, Li-Bin Sun, Ning Liu, Jie Sheng, Wen-Sheng Qiu
Pages: 448-454 Published online on: 13 May 2016
Article
Upregulation of ABCG2 via the PI3K-Akt pathway contributes to acidic microenvironment-induced cisplatin resistance in A549 and LTEP-a-2 lung cancer cells
Chun Fang Hu, Yi Ying Huang, Yong Jie Wang, Feng Guang Gao
Pages: 455-461 Published online on: 23 May 2016
Article
Transcriptional network in ovarian cancer cell line SKOV3 treated with Pinellia pedatisecta Schott extract
Li Zhou, Teng Xu, Ying Zhang, Mei Zhu, Wen Zhu, Ziqiang Wang, Hangzhi Gu, Hanchu Wang, Peizhen Li, Jun Ying, Lei Yang, Ping Ren, Jinsong Li, Zuyuan Xu, Liyan Ni, Qiyu Bao, Jindong Chen
Pages: 462-470 Published online on: 28 April 2016
Article
MicroRNA-18b inhibits the growth of malignant melanoma via inhibition of HIF-1α-mediated glycolysis Retraction in /10.3892/or.2021.8161
Yao Chen, Ziqing Zhang, Chengqun Luo, Zizi Chen, Jianda Zhou
Pages: 471-479 Published online on: 20 May 2016
Article
miR-410-3p suppresses breast cancer progression by targeting Snail
Ya-Feng Zhang, Yue Yu, Wang-Zhao Song, Rui-Ming Zhang, Shan Jin, Jun-Wen Bai, Hong-Bin Kang, Xin Wang, Xu-Chen Cao
Pages: 480-486 Published online on: 23 May 2016
Article
miR-375 inhibits the invasion and metastasis of colorectal cancer via targeting SP1 and regulating EMT-associated genes
Fengyun Cui, Shuyang Wang, Iweng Lao, Chunxian Zhou, Hui Kong, Nayima Bayaxi, Jiali Li, Qi Chen, Tengfang Zhu, Hongguang Zhu
Pages: 487-493 Published online on: 24 May 2016
Article
Expression and inhibitory role of TIMP-3 in hepatocellular carcinoma
Bo Shen, Yingjie Jiang, Yuan-Ran Chen, Hui-Cong Zheng, Wei Zeng, Yu-Yuan Li, Aoxian Yin, Yuqiang Nie
Pages: 494-502 Published online on: 18 May 2016
Article
Comparative analysis of macrophage transcriptomes reveals a key mechanism of the immunomodulatory activity of Tricholoma matsutake polysaccharide
Xiang Ding, Jian Li, Yiling Hou, Wanru Hou
Pages: 503-513 Published online on: 18 May 2016
Article
Usefulness of a fluorescence visualization system for the detection of oral precancerous and early cancerous lesions
Yuichi Ohnishi, Tomoko Fujii, Yoshihide Ugaki, Hiroki Yasui, Masahiro Watanabe, Suguru Dateoka, Kenji Kakudo
Pages: 514-520 Published online on: 28 April 2016
Article
Hypoxia inducible factor-1α-dependent epithelial to mesenchymal transition under hypoxic conditions in prostate cancer cells
Mingchuan Li, Yong Xing Wang, Yong Luo, Jiahui Zhao, Qing Li, Jiao Zhang, Yongguang Jiang
Pages: 521-527 Published online on: 25 April 2016
Article
Anticancer activity of 7,8-dihydroxyflavone in melanoma cells via downregulation of α-MSH/cAMP/MITF pathway
Deok Yong Sim, Jae Kyung Sohng, Hye Jin Jung
Pages: 528-534 Published online on: 20 May 2016
Article
Synaptotagmin-like protein 2 gene promotes the metastatic potential in ovarian cancer
Hye Youn Sung, Jihye Han, Woong Ju, Jung-Hyuck Ahn
Pages: 535-541 Published online on: 24 May 2016
Article
MicroRNA-874 inhibits growth, induces apoptosis and reverses chemoresistance in colorectal cancer by targeting X-linked inhibitor of apoptosis protein Retraction in /10.3892/or.2022.8280
Jinfeng Han, Zhongmin Liu, Nanya Wang, Weiyun Pan
Pages: 542-550 Published online on: 16 May 2016
Article
Overexpression of PAD4 suppresses drug resistance of NSCLC cell lines to gefitinib through inhibiting Elk1-mediated epithelial-mesenchymal transition
Qiong Duan, Cui Pang, Ning Chang, Ju Zhang, Wenchao Liu
Pages: 551-558 Published online on: 28 April 2016
Article
Skp2 is associated with paclitaxel resistance in prostate cancer cells
Yeguo Yang, Yi Lu, Lihui Wang, Atsushi Mizokami, Evan T. Keller, Jian Zhang, Jiejun Fu
Pages: 559-566 Published online on: 13 May 2016
Article
Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis
Yuwan Zhao, Zuolei Jing, Yan Li, Weifeng Mao
Pages: 567-572 Published online on: 05 May 2016
Article
Clinicopathological implications of vascular endothelial growth factor 165b expression in oral squamous cell carcinoma stroma
Masahiro Nagasaki, Seiji Kondo, Yoshiki Mukudai, Takaaki Kamatani, Ayako Akizuki, Atsushi Yaso, Toshikazu Shimane, Tatsuo Shirota
Pages: 573-581 Published online on: 20 May 2016
Article
Hepatitis C virus core protein regulates OCT4 expression and promotes cell cycle progression in hepatocellular carcinoma
Jia-Jia Zhou, Zhe Meng, Yu Zhou, Di Cheng, Hui-Lin Ye, Quan-Bo Zhou, Xiao-Geng Deng, Ru-Fu Chen
Pages: 582-588 Published online on: 27 April 2016
Article
