|
1
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hussain A, Qazi AK, Mupparapu N, Guru SK,
Kumar A, Sharma PR, Singh SK, Singh P, Dar MJ, Bharate SB, et al:
Modulation of glycolysis and lipogenesis by novel PI3K selective
molecule represses tumor angiogenesis and decreases colorectal
cancer growth. Cancer Lett. 374:250–260. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Saha S, Ghosh M and Dutta SK: Role of
metabolic modulator Bet-CA in altering mitochondrial
hyperpolarization to suppress cancer associated angiogenesis and
metastasis. Sci Rep. 6:235522016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Leung CO, Wong CC, Fan DN, Kai AK, Tung
EK, Xu IM, Ng IO and Lo RC: PIM1 regulates glycolysis and promotes
tumor progression in hepatocellular carcinoma. Oncotarget.
6:10880–10892. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Liu Y, Cao Y, Zhang W, Bergmeier S, Qian
Y, Akbar H, Colvin R, Ding J, Tong L, Wu S, et al: A small-molecule
inhibitor of glucose transporter 1 downregulates glycolysis,
induces cell-cycle arrest, and inhibits cancer cell growth in vitro
and in vivo. Mol Cancer Ther. 11:1672–1682. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Talekar M, Boreddy SR, Singh A and Amiji
M: Tumor aerobic glycolysis: New insights into therapeutic
strategies with targeted delivery. Expert Opin Biol Ther.
14:1145–1159. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kaplon J, Zheng L, Meissl K, Chaneton B,
Selivanov VA, Mackay G, van der Burg SH, Verdegaal EM, Cascante M,
Shlomi T, et al: A key role for mitochondrial gatekeeper pyruvate
dehydrogenase in oncogene-induced senescence. Nature. 498:109–112.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Doherty JR, Yang C, Scott KE, Cameron MD,
Fallahi M, Li W, Hall MA, Amelio AL, Mishra JK, Li F, et al:
Blocking lactate export by inhibiting the Myc target MCT1 disables
glycolysis and glutathione synthesis. Cancer Res. 74:908–920. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhou Y, Tozzi F, Chen J, Fan F, Xia L,
Wang J, Gao G, Zhang A, Xia X, Brasher H, et al: Intracellular ATP
levels are a pivotal determinant of chemoresistance in colon cancer
cells. Cancer Res. 72:304–314. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lu CW, Lin SC, Chen KF, Lai YY and Tsai
SJ: Induction of pyruvate dehydrogenase kinase-3 by
hypoxia-inducible factor-1 promotes metabolic switch and drug
resistance. J Biol Chem. 283:28106–28114. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Hsu PP and Sabatini DM: Cancer cell
metabolism: Warburg and beyond. Cell. 134:703–707. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
DeBerardinis RJ, Lum JJ, Hatzivassiliou G
and Thompson CB: The biology of cancer: Metabolic reprogramming
fuels cell growth and proliferation. Cell Metab. 7:11–20. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lehen'kyi V and Prevarskaya N: Oncogenic
TRP channels. Adv Exp Med Biol. 704:929–945. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ding X, He Z, Zhou K, Cheng J, Yao H, Lu
D, Cai R, Jin Y, Dong B, Xu Y, et al: Essential role of TRPC6
channels in G2/M phase transition and development of human glioma.
J Natl Cancer Inst. 102:1052–1068. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
El Hiani Y, Ahidouch A, Lehen'kyi V, Hague
F, Gouilleux F, Mentaverri R, Kamel S, Lassoued K, Brûlé G and
Ouadid-Ahidouch H: Extracellular signal-regulated kinases 1 and 2
and TRPC1 channels are required for calcium-sensing
receptor-stimulated MCF-7 breast cancer cell proliferation. Cell
Physiol Biochem. 23:335–346. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yang SL, Cao Q, Zhou KC, Feng YJ and Wang
YZ: Transient receptor potential channel C3 contributes to the
progression of human ovarian cancer. Oncogene. 28:1320–1328. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
El Boustany C, Bidaux G, Enfissi A,
Delcourt P, Prevarskaya N and Capiod T: Capacitative calcium entry
and transient receptor potential canonical 6 expression control
human hepatoma cell proliferation. Hepatology. 47:2068–2077. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Thebault S, Flourakis M, Vanoverberghe K,
Vandermoere F, Roudbaraki M, Lehen'kyi V, Slomianny C, Beck B,
Mariot P, Bonnal JL, et al: Differential role of transient receptor
potential channels in Ca2+ entry and proliferation of
prostate cancer epithelial cells. Cancer Res. 66:2038–2047. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wang T, Chen Z, Zhu Y, Pan Q, Liu Y, Qi X,
Jin L, Jin J, Ma X and Hua D: Inhibition of transient receptor
potential channel 5 reverses 5-Fluorouracil resistance in human
colorectal cancer cells. J Biol Chem. 290:448–456. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Osthus RC, Shim H, Kim S, Li Q, Reddy R,
Mukherjee M, Xu Y, Wonsey D, Lee LA and Dang CV: Deregulation of
glucose transporter 1 and glycolytic gene expression by c-Myc. J
Biol Chem. 275:21797–21800. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Eisenhauer EA, Therasse P, Bogaerts J,
Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S,
Mooney M, et al: New response evaluation criteria in solid tumours:
Revised RECIST guideline (version 1.1). Eur J Cancer. 45:228–247.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Koo CL, Kok LF, Lee MY, Wu TS, Cheng YW,
Hsu JD, Ruan A, Chao KC and Han CP: Scoring mechanisms of
p16INK4a immunohistochemistry based on either
independent nucleic stain or mixed cytoplasmic with nucleic
expression can significantly signal to distinguish between
endocervical and endometrial adenocarcinomas in a tissue microarray
study. J Transl Med. 7:252009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Pate KT, Stringari C, Sprowl-Tanio S, Wang
K, TeSlaa T, Hoverter NP, McQuade MM, Garner C, Digman MA, Teitell
MA, et al: Wnt signaling directs a metabolic program of glycolysis
and angiogenesis in colon cancer. EMBO J. 33:1454–1473.
2014.PubMed/NCBI
|
|
25
|
Xu X, Li J, Sun X, Guo Y, Chu D, Wei L, Li
X, Yang G, Liu X, Yao L, et al: Tumor suppressor NDRG2 inhibits
glycolysis and glutaminolysis in colorectal cancer cells by
repressing c-Myc expression. Oncotarget. 6:26161–26176. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Warburg O: On the origin of cancer cells.
Science. 123:309–314. 1956. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kroemer G and Pouyssegur J: Tumor cell
metabolism: Cancer's Achilles' heel. Cancer Cell. 13:472–482. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Heiden MG Vander, Cantley LC and Thompson
CB: Understanding the Warburg effect: The metabolic requirements of
cell proliferation. Science. 324:1029–1033. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ward PS and Thompson CB: Metabolic
reprogramming: A cancer hallmark even warburg did not anticipate.
Cancer Cell. 21:297–308. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Oronsky BT, Oronsky N, Fanger GR, Parker
CW, Caroen SZ, Lybeck M and Scicinski JJ: Follow the ATP: tumor
energy production: a perspective. Anticancer Agents Med Chem.
14:1187–1198. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Levine AJ and Puzio-Kuter AM: The control
of the metabolic switch in cancers by oncogenes and tumor
suppressor genes. Science. 330:1340–1344. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Muñoz-Pinedo C, El Mjiyad N and Ricci JE:
Cancer metabolism: Current perspectives and future directions. Cell
Death Dis. 3:e2482012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Ganapathy-Kanniappan S and Geschwind JF:
Tumor glycolysis as a target for cancer therapy: Progress and
prospects. Mol Cancer. 12:1522013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Jones RG and Thompson CB: Tumor
suppressors and cell metabolism: A recipe for cancer growth. Genes
Dev. 23:537–548. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Robey RB and Hay N: Is Akt the ‘Warburg
kinase’? - Akt-energy metabolism interactions and oncogenesis.
Semin Cancer Biol. 19:25–31. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Bush EW, Hood DB, Papst PJ, Chapo JA,
Minobe W, Bristow MR, Olson EN and McKinsey TA: Canonical transient
receptor potential channels promote cardiomyocyte hypertrophy
through activation of calcineurin signaling. J Biol Chem.
281:33487–33496. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Vennekens R, Menigoz A and Nilius B: TRPs
in the Brain. Rev Physiol Biochem Pharmacol. 163:27–64.
2012.PubMed/NCBI
|
|
38
|
Lehen'kyi V, Flourakis M, Skryma R and
Prevarskaya N: TRPV6 channel controls prostate cancer cell
proliferation via Ca2+/NFAT-dependent pathways.
Oncogene. 26:7380–7385. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Jiang HN, Zeng B, Zhang Y, Daskoulidou N,
Fan H, Qu JM and Xu SZ: Involvement of TRPC channels in lung cancer
cell differentiation and the correlation analysis in human
non-small cell lung cancer. PLoS One. 8:e676372013. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Pla A Fiorio, Avanzato D, Munaron L and
Ambudkar IS: Ion channels and transporters in cancer. 6.
Vascularizing the tumor: TRP channels as molecular targets. Am J
Physiol Cell Physiol. 302:C9–C15. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Longley DB and Johnston PG: Molecular
mechanisms of drug resistance. J Pathol. 205:275–292. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Numata T, Ogawa N, Takahashi N and Mori Y:
TRP channels as sensors of oxygen availability. Pflugers Arch.
465:1075–1085. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Ma X, Cai Y, He D, Zou C, Zhang P, Lo CY,
Xu Z, Chan FL, Yu S, Chen Y, et al: Transient receptor potential
channel TRPC5 is essential for P-glycoprotein induction in
drug-resistant cancer cells. Proc Natl Acad Sci USA.
109:16282–16287. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Ma X, Chen Z, Hua D, He D, Wang L, Zhang
P, Wang J, Cai Y, Gao C, Zhang X, et al: Essential role for
TrpC5-containing extracellular vesicles in breast cancer with
chemotherapeutic resistance. Proc Natl Acad Sci USA. 111:6389–6394.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Zhu Y, Pan Q, Meng H, Jiang Y, Mao A, Wang
T, Hua D, Yao X, Jin J and Ma X: Enhancement of vascular
endothelial growth factor release in long-term drug-treated breast
cancer via transient receptor potential channel
5-Ca2+-hypoxia-inducible factor 1α pathway. Pharmacol
Res. 93:36–42. 2015. View Article : Google Scholar : PubMed/NCBI
|
