|
1
|
Louis DN, Ohgaki H, Wiestler OD, Cavenee
WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007
WHO classification of tumours of the central nervous system. Acta
Neuropathol. 114:97–109. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Gielen PR, Aftab Q, Ma N, Chen VC, Hong X,
Lozinsky S, Naus CC and Sin WC: Connexin43 confers Temozolomide
resistance in human glioma cells by modulating the mitochondrial
apoptosis pathway. Neuropharmacology. 75:539–548. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Alifieris C and Trafalis DT: Glioblastoma
multiforme: Pathogenesis and treatment. Pharmacol Ther. 152:63–82.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Razis Abdull AF and Noor NM: Cruciferous
vegetables: Dietary phytochemicals for cancer prevention. Asian Pac
J Cancer Prev. 14:1565–1570. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Clarke JD, Hsu A, Yu Z, Dashwood RH and Ho
E: Differential effects of sulforaphane on histone deacetylases,
cell cycle arrest and apoptosis in normal prostate cells versus
hyperplastic and cancerous prostate cells. Mol Nutr Food Res.
55:999–1009. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Pham NA, Jacobberger JW, Schimmer AD, Cao
P, Gronda M and Hedley DW: The dietary isothiocyanate sulforaphane
targets pathways of apoptosis, cell cycle arrest, and oxidative
stress in human pancreatic cancer cells and inhibits tumor growth
in severe combined immunodeficient mice. Mol Cancer Ther.
3:1239–1248. 2004.PubMed/NCBI
|
|
7
|
Karmakar S, Weinberg MS, Banik NL, Patel
SJ and Ray SK: Activation of multiple molecular mechanisms for
apoptosis in human malignant glioblastoma T98G and U87MG cells
treated with sulforaphane. Neuroscience. 141:1265–1280. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Clarke JD, Hsu A, Williams DE, Dashwood
RH, Stevens JF, Yamamoto M and Ho E: Metabolism and tissue
distribution of sulforaphane in Nrf2 knockout and wild-type mice.
Pharm Res. 28:3171–3179. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Dinkova-Kostova AT and Kostov RV:
Glucosinolates and isothiocyanates in health and disease. Trends
Mol Med. 18:337–347. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yao A, Shen Y, Wang A, Chen S, Zhang H,
Chen F, Chen Z, Wei H, Zou Z, Shan Y, et al: Sulforaphane induces
apoptosis in adipocytes via Akt/p70s6k1/Bad inhibition and ERK
activation. Biochem Biophys Res Commun. 465:696–701. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wang L, Tian Z, Yang Q, Li H, Guan H, Shi
B, Hou P and Ji M: Sulforaphane inhibits thyroid cancer cell growth
and invasiveness through the reactive oxygen species-dependent
pathway. Oncotarget. 6:25917–25931. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Li C, Zhou Y, Peng X, Du L, Tian H, Yang
G, Niu J and Wu W: Sulforaphane inhibits invasion via activating
ERK1/2 signaling in human glioblastoma U87MG and U373MG cells. PLoS
One. 9:e905202014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Peng X, Zhou Y, Tian H, Yang G, Li C, Geng
Y, Wu S and Wu W: Sulforaphane inhibits invasion by phosphorylating
ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer
DU145 cells. Oncol Rep. 34:1565–1572. 2015.PubMed/NCBI
|
|
14
|
Shankar S, Ganapathy S and Srivastava RK:
Sulforaphane enhances the therapeutic potential of TRAIL in
prostate cancer orthotopic model through regulation of apoptosis,
metastasis, and angiogenesis. Clin Cancer Res. 14:6855–6866. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhang Z, Li C, Shang L, Zhang Y, Zou R,
Zhan Y and Bi B: Sulforaphane induces apoptosis and inhibits
invasion in U251MG glioblastoma cells. Springerplus. 5:2352016.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Myzak MC, Karplus PA, Chung FL and
Dashwood RH: A novel mechanism of chemoprotection by sulforaphane:
Inhibition of histone deacetylase. Cancer Res. 64:5767–5774. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Deschênes-Simard X, Kottakis F, Meloche S
and Ferbeyre G: ERKs in cancer: Friends or foes? Cancer Res.
74:412–419. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Tong WG, Ding XZ, Talamonti MS, Bell RH
and Adrian TE: LTB4 stimulates growth of human pancreatic cancer
cells via MAPK and PI-3 kinase pathways. Biochem Biophys Res
Commun. 335:949–956. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lee WJ, Hsiao M, Chang JL, Yang SF, Tseng
TH, Cheng CW, Chow JM, Lin KH, Lin YW, Liu CC, et al: Quercetin
induces mitochondrial-derived apoptosis via reactive oxygen
species-mediated ERK activation in HL-60 leukemia cells and
xenograft. Arch Toxicol. 89:1103–1117. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Tian H, Zhou Y, Yang G, Geng Y, Wu S, Hu
Y, Lin K and Wu W: Sulforaphane-cysteine suppresses invasion via
downregulation of galectin-1 in human prostate cancer DU145 and PC3
cells. Oncol Rep. 36:1361–1368. 2016.PubMed/NCBI
|
|
21
|
Manero F, Gautier F, Gallenne T, Cauquil
N, Grée D, Cartron PF, Geneste O, Grée R, Vallette FM and Juin P:
The small organic compound HA14-1 prevents Bcl-2 interaction with
Bax to sensitize malignant glioma cells to induction of cell death.
Cancer Res. 66:2757–2764. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Cartron PF, Oliver L, Martin S, Moreau C,
LeCabellec MT, Jezequel P, Meflah K and Vallette FM: The expression
of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is
correlated with an increased survival of glioblastoma multiforme
patients. Hum Mol Genet. 11:675–687. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
George J, Banik NL and Ray SK: Combination
of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma
cells and inhibits invasion, angiogenesis and tumour growth. J Cell
Mol Med. 13:4205–4218. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wick W, Grimmel C, Wild-Bode C, Platten M,
Arpin M and Weller M: Ezrin-dependent promotion of glioma cell
clonogenicity, motility, and invasion mediated by BCL-2 and
transforming growth factor-beta2. J Neurosci. 21:3360–3368.
2001.PubMed/NCBI
|
|
25
|
Thomas S, Quinn BA, Das SK, Dash R, Emdad
L, Dasgupta S, Wang XY, Dent P, Reed JC, Pellecchia M, et al:
Targeting the Bcl-2 family for cancer therapy. Expert Opin Ther
Targets. 17:61–75. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
van Delft MF and Huang DC: How the Bcl-2
family of proteins interact to regulate apoptosis. Cell Res.
16:203–213. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yin XM, Oltvai ZN and Korsmeyer SJ: BH1
and BH2 domains of Bcl-2 are required for inhibition of apoptosis
and heterodimerization with Bax. Nature. 369:321–323. 1994.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Shi L, Chen J, Yang J, Pan T, Zhang S and
Wang Z: MiR-21 protected human glioblastoma U87MG cells from
chemotherapeutic drug temozolomide induced apoptosis by decreasing
Bax/Bcl-2 ratio and caspase-3 activity. Brain Res. 1352:255–264.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Skała E, Sitarek P, Toma M, Szemraj J,
Radek M, Nieborowska-Skorska M, Skorski T, Wysokińska H and
Śliwiński T: Inhibition of human glioma cell proliferation by
altered Bax/Bcl-2-p53 expression and apoptosis induction by
Rhaponticum carthamoides extracts from transformed and
normal roots. J Pharm Pharmacol. 68:1454–1464. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yating Q, Yuan Y, Wei Z, Qing G, Xingwei
W, Qiu Q and Lili Y: Oxidized LDL induces apoptosis of human
retinal pigment epithelium through activation of ERK-Bax/Bcl-2
signaling pathways. Curr Eye Res. 40:415–422. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Nuñez G, Benedict MA, Hu Y and Inohara N:
Caspases: The proteases of the apoptotic pathway. Oncogene.
17:3237–3245. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Riedl SJ and Shi Y: Molecular mechanisms
of caspase regulation during apoptosis. Nat Rev Mol Cell Biol.
5:897–907. 2004. View
Article : Google Scholar : PubMed/NCBI
|
|
33
|
Tait SW and Green DR: Mitochondria and
cell death: Outer membrane permeabilization and beyond. Nat Rev Mol
Cell Biol. 11:621–632. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
34
|
Walters J, Pop C, Scott FL, Drag M, Swartz
P, Mattos C, Salvesen GS and Clark AC: A constitutively active and
uninhibitable caspase-3 zymogen efficiently induces apoptosis.
Biochem J. 424:335–345. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yu SW, Wang H, Poitras MF, Coombs C,
Bowers WJ, Federoff HJ, Poirier GG, Dawson TM and Dawson VL:
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by
apoptosis-inducing factor. Science. 297:259–263. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Huang TY, Chang WC, Wang MY, Yang YR and
Hsu YC: Effect of sulforaphane on growth inhibition in human brain
malignant glioma GBM 8401 cells by means of mitochondrial- and
MEK/ERK-mediated apoptosis pathway. Cell Biochem Biophys.
63:247–259. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Jiang H, Shang X, Wu H, Huang G, Wang Y,
Al-Holou S, Gautam SC and Chopp M: Combination treatment with
resveratrol and sulforaphane induces apoptosis in human U251 glioma
cells. Neurochem Res. 35:152–161. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Shapiro TA, Fahey JW, Dinkova-Kostova AT,
Holtzclaw WD, Stephenson KK, Wade KL, Ye L and Talalay P: Safety,
tolerance, and metabolism of broccoli sprout glucosinolates and
isothiocyanates: A clinical phase I study. Nutr Cancer. 55:53–62.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Alejandro EU and Johnson JD: Inhibition of
Raf-1 alters multiple downstream pathways to induce pancreatic
beta-cell apoptosis. J Biol Chem. 283:2407–2417. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Yuan S, Wen J, Cheng J, Shen W, Zhou S,
Yan W, Shen L, Luo A and Wang S: Age-associated up-regulation of
EGR1 promotes granulosa cell apoptosis during follicle atresia in
mice through the NF-κB pathway. Cell Cycle. 15:2895–2905. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Zhou Z, Lu X, Wang J, Xiao J, Liu J and
Xing F: microRNA let-7c is essential for the anisomycin-elicited
apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3
signaling. Sci Rep. 6:244342016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Al-Sarraj A and Thiel G: Substance P
induced biosynthesis of the zinc finger transcription factor Egr-1
in human glioma cells requires activation of the epidermal growth
factor receptor and of extracellular signal-regulated protein
kinase. Neurosci Lett. 332:111–114. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Li L, Zhao LM, Dai SL, Cui WX, Lv HL, Chen
L and Shan BE: Periplocin extracted from cortex periplocae
induced apoptosis of gastric cancer cells via the ERK1/2-EGR1
pathway. Cell Physiol Biochem. 38:1939–1951. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Yang M, Teng W, Qu Y, Wang H and Yuan Q:
Sulforaphene inhibits triple negative breast cancer through
activating tumor suppressor Egr1. Breast Cancer Res Treat.
158:277–286. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Zhang DX, Ma DY, Yao ZQ, Fu CY, Shi YX,
Wang QL and Tang QQ: ERK1/2/p53 and NF-κB dependent-PUMA activation
involves in doxorubicin-induced cardiomyocyte apoptosis. Eur Rev
Med Pharmacol Sci. 20:2435–2442. 2016.PubMed/NCBI
|
|
46
|
Wang Q, Liu S, Tang Y, Liu Q and Yao Y:
MPT64 protein from Mycobacterium tuberculosis inhibits apoptosis of
macrophages through NF-κB-miRNA21-Bcl-2 pathway. PLoS One.
9:e1009492014. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Sitarek P, Skała E, Toma M, Wielanek M,
Szemraj J, Nieborowska-Skorska M, Kolasa M, Skorski T, Wysokińska H
and Śliwiński T: A preliminary study of apoptosis induction in
glioma cells via alteration of the Bax/Bcl-2-p53 axis by
transformed and non-transformed root extracts of Leonurus
sibiricus L. Tumour Biol. 37:8753–8764. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Fulda S and Vucic D: Targeting IAP
proteins for therapeutic intervention in cancer. Nat Rev Drug
Discov. 11:109–124. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Ashkenazi A and Dixit VM: Death receptors:
Signaling and modulation. Science. 281:1305–1308. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Hengartner MO: The biochemistry of
apoptosis. Nature. 407:770–776. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Indran IR, Tufo G, Pervaiz S and Brenner
C: Recent advances in apoptosis, mitochondria and drug resistance
in cancer cells. Biochim Biophys Acta. 1807:735–745. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Sano R and Reed JC: ER stress-induced cell
death mechanisms. Biochim Biophys Acta. 1833:3460–3470. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Cagnol S and Chambard JC: ERK and cell
death: Mechanisms of ERK-induced cell death - apoptosis, autophagy
and senescence. FEBS J. 277:2–21. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Abdi A, Sadraie H, Dargahi L, Khalaj L and
Ahmadiani A: Apoptosis inhibition can be threatening in Aβ-induced
neuroinflammation, through promoting cell proliferation. Neurochem
Res. 36:39–48. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Virág L and Szabó C: The therapeutic
potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev.
54:375–429. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Wang XH and Mitch WE: Muscle wasting from
kidney failure - a model for catabolic conditions. Int J Biochem
Cell Biol. 45:2230–2238. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Sung M and Giannakakou P: BRCA1 regulates
microtubule dynamics and taxane-induced apoptotic cell signaling.
Oncogene. 33:1418–1428. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Giussani P, Bassi R, Anelli V, Brioschi L,
De Zen F, Riccitelli E, Caroli M, Campanella R, Gaini SM, Viani P,
et al: Glucosylceramide synthase protects glioblastoma cells
against autophagic and apoptotic death induced by temozolomide and
Paclitaxel. Cancer Invest. 30:27–37. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Chen H, Landen CN, Li Y, Alvarez RD and
Tollefsbol TO: Epigallocatechin gallate and sulforaphane
combination treatment induce apoptosis in paclitaxel-resistant
ovarian cancer cells through hTERT and Bcl-2 down-regulation. Exp
Cell Res. 319:697–706. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Balasubramanian S, Chew YC and Eckert RL:
Sulforaphane suppresses polycomb group protein level via a
proteasome-dependent mechanism in skin cancer cells. Mol Pharmacol.
80:870–878. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Yakovlev A, Khafizova M, Abdullaev Z,
Loukinov D and Kondratyev A: Epigenetic regulation of caspase-3
gene expression in rat brain development. Gene. 450:103–108. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Lee P, Murphy B, Miller R, Menon V, Banik
NL, Giglio P, Lindhorst SM, Varma AK, Vandergrift WA III, Patel SJ,
et al: Mechanisms and clinical significance of histone deacetylase
inhibitors: Epigenetic glioblastoma therapy. Anticancer Res.
35:615–625. 2015.PubMed/NCBI
|
