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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2017 Volume 37 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Search for useful biomarkers in hepatocellular carcinoma, tumor factors and background liver factors (Review)

Dai Shimizu, Yoshikuni Inokawa, Fuminori Sonohara, Kenichi Inaoka, Shuji Nomoto
Pages: 2527-2542
Published online on: 31 March 2017

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Review

Cancer-induced cardiac cachexia: Pathogenesis and impact of physical activity (Review)

Yassine Belloum, Françoise Rannou-Bekono, François B. Favier
Pages: 2543-2552
Published online on: 31 March 2017

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Review

Current status and future perspectives on treatment of liver metastasis in colorectal cancer (Review)

Mahdi Hussain Al Bandar, Nam Kyu Kim
Pages: 2553-2564
Published online on: 27 March 2017

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Article Open Access

Regulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1

Lei Wang, Bingxin Zhu, Shiquan Wang, Yuxuan Wu, Wenjian Zhan, Shao Xie, Hengliang Shi, Rutong Yu
Pages: 2565-2574
Published online on: 11 April 2017

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Article Open Access

SLC3A2 is upregulated in human osteosarcoma and promotes tumor growth through the PI3K/Akt signaling pathway

Bin Zhu, Dongdong Cheng, Lei Hou, Shumin Zhou, Tao Ying, Qingcheng Yang
Pages: 2575-2582
Published online on: 27 March 2017

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Article Open Access

MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression

Jiangman Duan, Lishan Chen, Minyu Zhou, Jingwen Zhang, Li Sun, Na Huang, Jianping Bin, Yulin Liao, Wangjun Liao
Pages: 2583-2592
Published online on: 22 March 2017

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Article Open Access

miR-539 inhibits FSCN1 expression and suppresses hepatocellular carcinoma migration and invasion

Yanping Liu, Wei Hong, Cancan Zhou, Zhengdong Jiang, Guanghui Wang, Guangbing Wei, Xuqi Li
Pages: 2593-2602
Published online on: 03 April 2017

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Article Open Access

Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer

Yuji Ikeda, Kazuma Kiyotani, Poh Yin Yew, Sho Sato, Yuichi Imai, Rui Yamaguchi, Satoru Miyano, Keiichi Fujiwara, Kosei Hasegawa, Yusuke Nakamura
Pages: 2603-2610
Published online on: 29 March 2017

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Article Open Access

Propofol suppresses LPS-induced nuclear accumulation of HIF-1α and tumor aggressiveness in non-small cell lung cancer

Nengli Yang, Yafeng Liang, Pei Yang, Fuhai Ji
Pages: 2611-2619
Published online on: 17 March 2017

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Article Open Access

Expression of Yes-associated protein 1 and its clinical significance in ovarian serous cystadenocarcinoma

Sang Yeon Cho, Kwanghun Kim, Min Soo Park, Mi Young Jang, Young Hwan Choi, Suyeon Han, Hyun Mo Shin, Chaeuk Chung, Hye Young Han, Jung Bo Yang, Young Bok Ko, Heon Jong Yoo
Pages: 2620-2632
Published online on: 21 March 2017

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Article Open Access

Metallothionein 1G promotes the differentiation of HT-29 human colorectal cancer cells

Juan Martín Arriaga, Alicia Inés Bravo, José Mordoh, Michele Bianchini
Pages: 2633-2651
Published online on: 03 April 2017

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Article Open Access

GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer Corrigendum in /10.3892/or.2021.8016

Fei Ouyang, Junling Liu, Meng Xia, Chuyong Lin, Xianqiu Wu, Liping Ye, Libing Song, Jun Li, Jing Wang, Peng Guo, Mian He
Pages: 2652-2662
Published online on: 11 April 2017

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Article Open Access

Relationship between epigenetic changes in Wnt antagonists and acute leukemia

Hua-Rong Zhou, Hai-Ying Fu, Dan-Sen Wu, Yuan-Yuan Zhang, Si-Han Huang, Cong-Jie Chen, Jian-Guo Yan, Jin-Long Huang, Jian-Zhen Shen
Pages: 2663-2671
Published online on: 15 March 2017

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Article Open Access

miR-597 inhibits breast cancer cell proliferation, migration and invasion through FOSL2

Jiangtu He, Jieying Mai, Yan Li, Linyi Chen, Hui Xu, Xiaofei Zhu, Qiuhui Pan
Pages: 2672-2678
Published online on: 05 April 2017

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Article Open Access

Dysregulated miR-27a-3p promotes nasopharyngeal carcinoma cell proliferation and migration by targeting Mapk10

Lihua Li, Zhaohui Luo
Pages: 2679-2687
Published online on: 31 March 2017

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Article Open Access

An ‘activatable’ aptamer-based fluorescence probe for the detection of HepG2 cells

Zongqiang Lai, Juntao Tan, Ruirong Wan, Jie Tan, Zhenghua Zhang, Zixi Hu, Jieping Li, Wei Yang, Yiwei Wang, Yafeng Jiang, Jian He, Nuo Yang, Xiaoling Lu, Yongxiang Zhao
Pages: 2688-2694
Published online on: 24 March 2017

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Article Open Access

The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer

Gang Chen, Hefen Yu, Lucy Satherley, Catherine Zabkiewicz, Jeyna Resaul, Huishan Zhao, Hu Mu, Xiuyi Zhi, Junqi He, Lin Ye, Wen G. Jiang
Pages: 2695-2701
Published online on: 31 March 2017

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Article Open Access

Circulating microRNA-194 regulates human melanoma cells via PI3K/AKT/FoxO3a and p53/p21 signaling pathway

Ming Bai, Mingzi Zhang, Fei Long, Nanze Yu, Ang Zeng, Ru Zhao
Pages: 2702-2710
Published online on: 30 March 2017

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Article Open Access

miR-200a targets Gelsolin: A novel mechanism regulating secretion of microvesicles in hepatocellular carcinoma cells

Ya Xu, Yanfen Zhang, Lujing Wang, Ruiqi Zhao, Yu Qiao, Dong Han, Qian Sun, Nazhen Dong, Yicong Liu, Dantong Wu, Xuemei Zhang, Ning Huang, Ning Ma, Weiming Zhao, Yanhong Liu, Xu Gao
Pages: 2711-2719
Published online on: 15 March 2017

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Article

miR-15b inhibits cancer-initiating cell phenotypes and chemoresistance of cisplatin by targeting TRIM14 in oral tongue squamous cell cancer

Xijun Wang, Hongmei Guo, Banjamin Yao, Julia Helms
Pages: 2720-2726
Published online on: 27 March 2017

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Article

Metabolomic analysis of the saliva of Japanese patients with oral squamous cell carcinoma

Mitsuyoshi Ohshima, Keisuke Sugahara, Kiyohiro Kasahara, Akira Katakura
Pages: 2727-2734
Published online on: 06 April 2017

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Article

With no interaction, knockdown of Apollon and MDR1 reverse the multidrug resistance of human chronic myelogenous leukemia K562/ADM cells

Jie-Ru Chen, Xiu-Hong Jia, Hong Wang, Ying-Jie Yi, You-Jie Li
Pages: 2735-2742
Published online on: 29 March 2017

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Article

MicroRNA-329-3p targets MAPK1 to suppress cell proliferation, migration and invasion in cervical cancer Retraction in /10.3892/or.2024.8745

Wenfeng Li, Jingjing Liang, Zhechao Zhang, Hongyan Lou, Liang Zhao, Yunsheng Xu, Rongying Ou
Pages: 2743-2750
Published online on: 05 April 2017

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Article

siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells Corrigendum in /10.3892/or.2021.7922 Retraction in /10.3892/or.2022.8438

Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu Hu
Pages: 2751-2760
Published online on: 11 April 2017

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Article

Bladder intracavitary hyperthermic perfusion chemotherapy for the prevention of recurrence of non-muscle invasive bladder cancer after transurethral resection

Mingchen Ba, Shuzhong Cui, Bin Wang, Hui Long, Zhaofei Yan, Shuai Wang, Yinbing Wu, Yuanfeng Gong
Pages: 2761-2770
Published online on: 11 April 2017

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Article

Proteomic-based identification of HSP70 as a tumor-associated antigen in ovarian cancer

Xin-Xin Liu, Hua Ye, Peng Wang, Liu-Xia Li, Yi Zhang, Jian-Ying Zhang
Pages: 2771-2778
Published online on: 24 March 2017

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Article

Integrated analysis of mRNA and miRNA expression profiles in pancreatic ductal adenocarcinoma

Hongwei Sun, Liang Zhao, Kehua Pan, Zhao Zhang, Mengtao Zhou, Guoquan Cao
Pages: 2779-2786
Published online on: 24 March 2017

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Article

MicroRNA-187 modulates epithelial-mesenchymal transition by targeting PTRF in non-small cell lung cancer

Yanjun Cai, Jian Ruan, Xueqing Yao, Liang Zhao, Baocheng Wang
Pages: 2787-2794
Published online on: 03 April 2017

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Article

Tetrandrine inhibits the proliferation of human osteosarcoma cells by upregulating the PTEN pathway

Dong-Dong Tian, Ran-Xi Zhang, Nian Wu, Wei Yuan, Shuai-Hong Luo, Hou‑Qing Chen, Yang Liu, Yang Wang, Bai-Cheng He, Zhong-Liang Deng
Pages: 2795-2802
Published online on: 06 April 2017

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Article

Pharmacokinetics, biodistribution and antitumour effects of Sclerotium rolfsii lectin in mice

Anupama S, Preeti Laha, Mamta Sharma, Kamal Pathak, Sanjay Bane, Arvind D. Ingle, Vikram Gota, Rajiv D. Kalraiya, Lu-Gang Yu, Jonathan M. Rhodes, Bale M. Swamy, Shashikala R. Inamdar
Pages: 2803-2810
Published online on: 03 April 2017

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Article

HBx represses RIZ1 expression by DNA methyltransferase 1 involvement in decreased miR-152 in hepatocellular carcinoma

Zhujiang Zhao, Ying Hu, Xiaohui Shen, Yingbin Lao, Lihua Zhang, Xuemei Qiu, Jiaojiao Hu, Pihai Gong, He Cui, Sen Lu, Ying Zheng, Menghan Zhou, Hong Fan
Pages: 2811-2818
Published online on: 21 March 2017

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Article

The specific killing effect of matrine on castration-resistant prostate cancer cells by targeting the Akt/FoxO3a signaling pathway Corrigendum in /10.3892/or.2020.7784

Shoumin Bai, Ting Chen, Xiaoli Yu, Ming Luo, Xianju Chen, Chunhao Lin, Yiming Lai, Hai Huang
Pages: 2819-2828
Published online on: 16 March 2017

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Article

Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells

Sai Wu, Yan Zhou, Gaoxiang Yang, Hua Tian, Yang Geng, Yabin Hu, Kai Lin, Wei Wu
Pages: 2829-2838
Published online on: 06 April 2017

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Article

SPAG6 regulates cell apoptosis through the TRAIL signal pathway in myelodysplastic syndromes

Xinxin Li, Bihui Yang, Li Wang, Liping Chen, Xiaohua Luo, Lin Liu
Pages: 2839-2846
Published online on: 31 March 2017

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Article

Nobiletin inhibits invasion via inhibiting AKT/GSK3β/β-catenin signaling pathway in Slug-expressing glioma cells

Xiang Zhang, Kebin Zheng, Chunhui Li, Yonghui Zhao, Heyang Li, Xuguang Liu, Yinbo Long, Junchao Yao
Pages: 2847-2856
Published online on: 23 March 2017

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Article

P21 activated kinase 4 binds translation elongation factor eEF1A1 to promote gastric cancer cell migration and invasion

Xiang Li, Jiabin Li, Feng Li
Pages: 2857-2864
Published online on: 31 March 2017

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Article

High ATP2A2 expression correlates with better prognosis of diffuse astrocytic tumor patients

Wei-Qing Li, Nan-Zhe Zhong, Jin He, Yi-Ming Li, Li-Jun Hou, Hui-Min Liu, Chun-Yan Xia, Liang-Zhe Wang, Yi-Cheng Lu
Pages: 2865-2874
Published online on: 24 March 2017

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Article

Maspin suppresses growth, proliferation and invasion in cutaneous squamous cell carcinoma cells

Hong Zhu, Qing Mao, Weiwei Liu, Zhenhai Yang, Xiaoqing Jian, Le Qu, Chundi He
Pages: 2875-2882
Published online on: 11 April 2017

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Article

Upregulated microRNA-429 inhibits the migration of HCC cells by targeting TRAF6 through the NF-κB pathway

Peng Wang, Jia Cao, Shihai Liu, Huazheng Pan, Xiangping Liu, Aihua Sui, Liping Wang, Ruyong Yao, Zimin Liu, Jun Liang
Pages: 2883-2890
Published online on: 15 March 2017

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Article

Inactivation of EGFR/AKT signaling enhances TSA-induced ovarian cancer cell differentiation

Genbao Shao, Wensheng Lai, Xiaolei Wan, Jing Xue, Ye Wei, Jie Jin, Liuping Zhang, Qiong Lin, Qixiang Shao, Shengqiang Zou
Pages: 2891-2896
Published online on: 05 April 2017

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Article

Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells

Shigeki Sumi, Naoki Umemura, Eiji Takayama, Emika Ohkoshi, Makoto Adachi, Masako Mizuno-Kamiya, Toshihiro Inagaki, Harumi Kawaki, Shinichiro Sumitomo, Nobuo Kondoh
Pages: 2897-2904
Published online on: 11 April 2017

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Article

Differential effects of sulforaphane in regulation of angiogenesis in a co-culture model of endothelial cells and pericytes

Yichong Wang, Zhigang Zhou, Wei Wang, Ming Liu, Yongping Bao
Pages: 2905-2912
Published online on: 11 April 2017

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Article

Inhibition of CCR7 promotes NF-κB-dependent apoptosis and suppresses epithelial-mesenchymal transition in non-small cell lung cancer

Lan Zhang, Xuyang Xiao, Hui An, Jian Wang, Yanmei Ma, Yi-Hua Qian
Pages: 2913-2919
Published online on: 23 March 2017

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Article

Downregulation of TNFAIP2 suppresses proliferation and metastasis in esophageal squamous cell carcinoma through activation of the Wnt/β-catenin signaling pathway

Yunbo Xie, Bin Wang
Pages: 2920-2928
Published online on: 05 April 2017

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Article

Inverse relationship between insulin receptor expression and progression in renal cell carcinoma

Makoto Takahashi, Takamitsu Inoue, Mingguo Huang, Kazuyuki Numakura, Hiroshi Tsuruta, Mitsuru Saito, Atsushi Maeno, Eijiro Nakamura, Shintaro Narita, Norihiko Tsuchiya, Tomonori Habuchi
Pages: 2929-2941
Published online on: 05 April 2017

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Article

A novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cell line Eca-109/5-FU with significant drug resistance-related characteristics

Chi Zhang, Qunfeng Ma, Yinan Shi, Xue Li, Ming Wang, Junfeng Wang, Jianlin Ge, Zhinan Chen, Ziling Wang, Hong Jiang
Pages: 2942-2954
Published online on: 31 March 2017

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Article

High expression of atonal homolog 8 predicts a poor clinical outcome in patients with colorectal cancer and contributes to tumor progression

Mengsi Ye, Yun He, Hao Lin, Shouxing Yang, Yuhui Zhou, Lingling Zhou, Jinwei Zhong, Guangrong Lu, Jihang Zheng, Zhan-Xiong Xue, Zhen-Zhai Cai
Pages: 2955-2963
Published online on: 05 April 2017

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Article

Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness

Naoki Nanashima, Kayo Horie, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida
Pages: 2964-2970
Published online on: 11 April 2017

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Article

Overexpression of RIP140 suppresses the malignant potential of hepatocellular carcinoma by inhibiting NF‑κB‑mediated alternative polarization of macrophages

Ying-Chun Hu, Zhu-Jun Yi, Yun Zhou, Pei-Zhi Li, Zuo-Jin Liu, Shi-Gang Duan, Jian-Ping Gong
Pages: 2971-2979
Published online on: 05 April 2017

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Article

Preparation of human single-chain variable fragment antibodies against anaplastic thyroid carcinoma, and single photon emission‑computed tomography/computed tomography imaging in tumor-bearing nude mice

Qian Liu, Hua Pang, Qiong Liu, Jing Zhou, Ying Liu
Pages: 2980-2986
Published online on: 05 April 2017

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Article

ROCK inhibition as a potential therapeutic target involved in apoptosis in hemangioma

Ming-Ke Qiu, Shu-Qing Wang, Chang Pan, Yang Wang, Zhi-Wei Quan, Ying-Bin Liu, Jing-Min Ou
Pages: 2987-2993
Published online on: 21 March 2017

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Article

Contribution of caspase-independent pathway to apoptosis in malignant glioma induced by carbon ion beams

Luwei Zhang, Jiawei Yan, Yang Liu, Qiuyue Zhao, Cuixia Di, Sun Chao, Li Jie, Yuanyuan Liu, Hong Zhang
Pages: 2994-3000
Published online on: 24 March 2017

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Article

Role of the cystathionine β-synthase/H2S system in liver cancer cells and the inhibitory effect of quinolone-indolone conjugate QIC2 on the system

Huina Jia, Juan Ye, Jing You, Xiaoyan Shi, Wenyi Kang, Tianxiao Wang
Pages: 3001-3009
Published online on: 17 March 2017

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Article

Hypoxia-induced miR-210 promoter demethylation enhances proliferation, autophagy and angiogenesis of schwannoma cells

Zhengguang Wang, Mingsi Deng, Zhendong Liu, Song Wu
Pages: 3010-3018
Published online on: 16 March 2017

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Article

Direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of PANC-1 cells

Jianhui Duan, Yilixiati Xiaokaiti, Shengjun Fan, Yan Pan, Xin Li, Xuejun Li
Pages: 3019-3025
Published online on: 21 March 2017

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Article

Overexpression of p53 protein is a marker of poor prognosis in Mexican women with breast cancer

Jisela Dimas-González, Vilma Maldonado-Lagunas, José Díaz‑Chávez, María Eugenia López-Arellano, José Muñoz-Camacho, Marco Antonio Terán-Porcayo, Alfredo Lagunas-Martínez
Pages: 3026-3036
Published online on: 05 April 2017

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Article

Recombinant adenovirus of SEA and CD80 genes driven by MMRE and mouse TERT promoter induce effective antitumor immune responses against different types of tumor cells in vitro and in vivo

Shao-Yan Si, Jun-Li Liu, Jun-Lian Liu, Bing-Xin Xu, Jian-Zhong Li, Ya-Ya Qin, Shu-Jun Song
Pages: 3037-3045
Published online on: 06 April 2017

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Article

BAMBI overexpression together with β-sitosterol ameliorates NSCLC via inhibiting autophagy and inactivating TGF-β/Smad2/3 pathway

Xingchun Wang, Minjie Li, Mengyao Hu, Ping Wei, Wei Zhu
Pages: 3046-3054
Published online on: 15 March 2017

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Triple-negative breast cancer: New therapeutic options via signalling transduction cascades

Ulrich Andergassen, Alexandra C. Kölbl, Jan-Niclas Mumm, Sven Mahner, Udo Jeschke
Pages: 3055-3060
Published online on: 16 March 2017

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Article

Transcriptional activation of PD-L1 by Sox2 contributes to the proliferation of hepatocellular carcinoma cells

Feng Zhong, Xinsheng Cheng, Shibo Sun, Jie Zhou
Pages: 3061-3067
Published online on: 23 March 2017

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CUTL1 induces epithelial-mesenchymal transition in non-small cell lung cancer

Junfeng Wang, Yanbo Wang, Dawei Sun, Fenghai Ren, Sainan Pang, Shidong Xu
Pages: 3068-3074
Published online on: 11 April 2017

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125I seed irradiation induces apoptosis and inhibits angiogenesis by decreasing HIF-1α and VEGF expression in lung carcinoma xenografts

Gui-Ling Xiang, Xin-Hong Zhu, Cun-Zhi Lin, Li-Jun Wang, Yong Sun, Yi-Wei Cao, Fang-Fang Wang
Pages: 3075-3083
Published online on: 23 March 2017

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Cross-validation of genes potentially associated with overall survival and drug resistance in ovarian cancer

Yutao Gao, Xia Liu, Ting Li, Luwei Wei, Antai Yang, Yi Lu, Jian Zhang, Li Li, Sumei Wang, Fuqiang Yin
Pages: 3084-3092
Published online on: 27 March 2017

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Long non-coding RNA MEG3 induces cell apoptosis in esophageal cancer through endoplasmic reticulum stress

Zhen-Lun Huang, Rui-Pei Chen, Xiao-Tao Zhou, Hao-Lian Zhan, Min-Min Hu, Bin Liu, Guan-Di Wu, Ling-Fei Wu
Pages: 3093-3099
Published online on: 11 April 2017

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Optimal method for quantitative detection of plasma EGFR T790M mutation using droplet digital PCR system

Ken Suzawa, Hiromasa Yamamoto, Kadoaki Ohashi, Shinsuke Hashida, Shuta Tomida, Toshio Kubo, Yuho Maki, Junichi Soh, Kazunori Tsukuda, Katsuyuki Kiura, Shinichiro Miyoshi, Shinichi Toyooka
Pages: 3100-3106
Published online on: 11 April 2017

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Article

Assessment of Th17 lymphocytes and cytokine IL‑17A in epithelial ovarian tumors

Izabela Winkler, Maria Pyszniak, Katarzyna Pogoda, Andrzej Semczuk, Marek Gogacz, Paweł Miotla, Aneta Adamiak, Dorota Darmochwal‑Kolarz, Tomasz Rechberger, Jacek Tabarkiewicz
Pages: 3107-3115
Published online on: 06 April 2017

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Article

miR-107 functions as a tumor suppressor in human esophageal squamous cell carcinoma and targets Cdc42

Priyanka Sharma, Neeru Saini, Rinu Sharma
Pages: 3116-3127
Published online on: 03 April 2017

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Article

Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor

Hideyoshi Kawasaki, Takuya Saotome, Tatsuya Usui, Takashi Ohama, Koichi Sato
Pages: 3128-3136
Published online on: 22 March 2017

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Article

Induction of galectin-1 by TLR-dependent PI3K activation enhances epithelial-mesenchymal transition of metastatic ovarian cancer cells

Ga Bin Park, Yoon Hee Chung, Daejin Kim
Pages: 3137-3145
Published online on: 27 March 2017

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Article

MicroRNA-30a-5p suppresses epithelial-mesenchymal transition by targeting profilin-2 in high invasive non-small cell lung cancer cell lines

Jiliang Yan, Chunyan Ma, Yue Gao
Pages: 3146-3154
Published online on: 11 April 2017

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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