Journal Articles

Review

Search for useful biomarkers in hepatocellular carcinoma, tumor factors and background liver factors (Review)

Dai Shimizu, Yoshikuni Inokawa, Fuminori Sonohara, Kenichi Inaoka, Shuji Nomoto

Pages: 2527-2542 Published online on: 31 March 2017
Review

Cancer-induced cardiac cachexia: Pathogenesis and impact of physical activity (Review)

Yassine Belloum, Françoise Rannou-Bekono, François B. Favier

Pages: 2543-2552 Published online on: 31 March 2017
Review

Current status and future perspectives on treatment of liver metastasis in colorectal cancer (Review)

Mahdi Hussain Al Bandar, Nam Kyu Kim

Pages: 2553-2564 Published online on: 27 March 2017
Article Open Access

Regulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1

Lei Wang, Bingxin Zhu, Shiquan Wang, Yuxuan Wu, Wenjian Zhan, Shao Xie, Hengliang Shi, Rutong Yu

Pages: 2565-2574 Published online on: 11 April 2017
Article Open Access

SLC3A2 is upregulated in human osteosarcoma and promotes tumor growth through the PI3K/Akt signaling pathway

Bin Zhu, Dongdong Cheng, Lei Hou, Shumin Zhou, Tao Ying, Qingcheng Yang

Pages: 2575-2582 Published online on: 27 March 2017
Article Open Access

MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression

Jiangman Duan, Lishan Chen, Minyu Zhou, Jingwen Zhang, Li Sun, Na Huang, Jianping Bin, Yulin Liao, Wangjun Liao

Pages: 2583-2592 Published online on: 22 March 2017
Article Open Access

miR-539 inhibits FSCN1 expression and suppresses hepatocellular carcinoma migration and invasion

Yanping Liu, Wei Hong, Cancan Zhou, Zhengdong Jiang, Guanghui Wang, Guangbing Wei, Xuqi Li

Pages: 2593-2602 Published online on: 03 April 2017
Article Open Access

Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer

Yuji Ikeda, Kazuma Kiyotani, Poh Yin Yew, Sho Sato, Yuichi Imai, Rui Yamaguchi, Satoru Miyano, Keiichi Fujiwara, Kosei Hasegawa, Yusuke Nakamura

Pages: 2603-2610 Published online on: 29 March 2017
Article Open Access

Propofol suppresses LPS-induced nuclear accumulation of HIF-1α and tumor aggressiveness in non-small cell lung cancer

Nengli Yang, Yafeng Liang, Pei Yang, Fuhai Ji

Pages: 2611-2619 Published online on: 17 March 2017
Article Open Access

Expression of Yes-associated protein 1 and its clinical significance in ovarian serous cystadenocarcinoma

Sang Yeon Cho, Kwanghun Kim, Min Soo Park, Mi Young Jang, Young Hwan Choi, Suyeon Han, Hyun Mo Shin, Chaeuk Chung, Hye Young Han, Jung Bo Yang, Young Bok Ko, Heon Jong Yoo

Pages: 2620-2632 Published online on: 21 March 2017
Article Open Access

Metallothionein 1G promotes the differentiation of HT-29 human colorectal cancer cells

Juan Martín Arriaga, Alicia Inés Bravo, José Mordoh, Michele Bianchini

Pages: 2633-2651 Published online on: 03 April 2017
Article Open Access

GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer Corrigendum in /10.3892/or.2021.8016

Fei Ouyang, Junling Liu, Meng Xia, Chuyong Lin, Xianqiu Wu, Liping Ye, Libing Song, Jun Li, Jing Wang, Peng Guo, Mian He

Pages: 2652-2662 Published online on: 11 April 2017
Article Open Access

Relationship between epigenetic changes in Wnt antagonists and acute leukemia

Hua-Rong Zhou, Hai-Ying Fu, Dan-Sen Wu, Yuan-Yuan Zhang, Si-Han Huang, Cong-Jie Chen, Jian-Guo Yan, Jin-Long Huang, Jian-Zhen Shen

Pages: 2663-2671 Published online on: 15 March 2017
Article Open Access

miR-597 inhibits breast cancer cell proliferation, migration and invasion through FOSL2

Jiangtu He, Jieying Mai, Yan Li, Linyi Chen, Hui Xu, Xiaofei Zhu, Qiuhui Pan

Pages: 2672-2678 Published online on: 05 April 2017
Article Open Access

Dysregulated miR-27a-3p promotes nasopharyngeal carcinoma cell proliferation and migration by targeting Mapk10

Lihua Li, Zhaohui Luo

Pages: 2679-2687 Published online on: 31 March 2017
Article Open Access

An ‘activatable’ aptamer-based fluorescence probe for the detection of HepG2 cells

Zongqiang Lai, Juntao Tan, Ruirong Wan, Jie Tan, Zhenghua Zhang, Zixi Hu, Jieping Li, Wei Yang, Yiwei Wang, Yafeng Jiang, Jian He, Nuo Yang, Xiaoling Lu, Yongxiang Zhao

Pages: 2688-2694 Published online on: 24 March 2017
Article Open Access

The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer

Gang Chen, Hefen Yu, Lucy Satherley, Catherine Zabkiewicz, Jeyna Resaul, Huishan Zhao, Hu Mu, Xiuyi Zhi, Junqi He, Lin Ye, Wen G. Jiang

Pages: 2695-2701 Published online on: 31 March 2017
Article Open Access

Circulating microRNA-194 regulates human melanoma cells via PI3K/AKT/FoxO3a and p53/p21 signaling pathway

Ming Bai, Mingzi Zhang, Fei Long, Nanze Yu, Ang Zeng, Ru Zhao

Pages: 2702-2710 Published online on: 30 March 2017
Article Open Access

miR-200a targets Gelsolin: A novel mechanism regulating secretion of microvesicles in hepatocellular carcinoma cells

Ya Xu, Yanfen Zhang, Lujing Wang, Ruiqi Zhao, Yu Qiao, Dong Han, Qian Sun, Nazhen Dong, Yicong Liu, Dantong Wu, Xuemei Zhang, Ning Huang, Ning Ma, Weiming Zhao, Yanhong Liu, Xu Gao

Pages: 2711-2719 Published online on: 15 March 2017
Article

miR-15b inhibits cancer-initiating cell phenotypes and chemoresistance of cisplatin by targeting TRIM14 in oral tongue squamous cell cancer

Xijun Wang, Hongmei Guo, Banjamin Yao, Julia Helms

Pages: 2720-2726 Published online on: 27 March 2017
Article

Metabolomic analysis of the saliva of Japanese patients with oral squamous cell carcinoma

Mitsuyoshi Ohshima, Keisuke Sugahara, Kiyohiro Kasahara, Akira Katakura

Pages: 2727-2734 Published online on: 06 April 2017
Article

With no interaction, knockdown of Apollon and MDR1 reverse the multidrug resistance of human chronic myelogenous leukemia K562/ADM cells

Jie-Ru Chen, Xiu-Hong Jia, Hong Wang, Ying-Jie Yi, You-Jie Li

Pages: 2735-2742 Published online on: 29 March 2017
Article

MicroRNA-329-3p targets MAPK1 to suppress cell proliferation, migration and invasion in cervical cancer Retraction in /10.3892/or.2024.8745

Wenfeng Li, Jingjing Liang, Zhechao Zhang, Hongyan Lou, Liang Zhao, Yunsheng Xu, Rongying Ou

Pages: 2743-2750 Published online on: 05 April 2017
Article

siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells Corrigendum in /10.3892/or.2021.7922 Retraction in /10.3892/or.2022.8438

Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu Hu

Pages: 2751-2760 Published online on: 11 April 2017
Article

Bladder intracavitary hyperthermic perfusion chemotherapy for the prevention of recurrence of non-muscle invasive bladder cancer after transurethral resection

Mingchen Ba, Shuzhong Cui, Bin Wang, Hui Long, Zhaofei Yan, Shuai Wang, Yinbing Wu, Yuanfeng Gong

Pages: 2761-2770 Published online on: 11 April 2017
Article

Proteomic-based identification of HSP70 as a tumor-associated antigen in ovarian cancer

Xin-Xin Liu, Hua Ye, Peng Wang, Liu-Xia Li, Yi Zhang, Jian-Ying Zhang

Pages: 2771-2778 Published online on: 24 March 2017
Article

Integrated analysis of mRNA and miRNA expression profiles in pancreatic ductal adenocarcinoma

Hongwei Sun, Liang Zhao, Kehua Pan, Zhao Zhang, Mengtao Zhou, Guoquan Cao

Pages: 2779-2786 Published online on: 24 March 2017
Article

MicroRNA-187 modulates epithelial-mesenchymal transition by targeting PTRF in non-small cell lung cancer

Yanjun Cai, Jian Ruan, Xueqing Yao, Liang Zhao, Baocheng Wang

Pages: 2787-2794 Published online on: 03 April 2017
Article

Tetrandrine inhibits the proliferation of human osteosarcoma cells by upregulating the PTEN pathway

Dong-Dong Tian, Ran-Xi Zhang, Nian Wu, Wei Yuan, Shuai-Hong Luo, Hou‑Qing Chen, Yang Liu, Yang Wang, Bai-Cheng He, Zhong-Liang Deng

Pages: 2795-2802 Published online on: 06 April 2017
Article

Pharmacokinetics, biodistribution and antitumour effects of Sclerotium rolfsii lectin in mice

Anupama S, Preeti Laha, Mamta Sharma, Kamal Pathak, Sanjay Bane, Arvind D. Ingle, Vikram Gota, Rajiv D. Kalraiya, Lu-Gang Yu, Jonathan M. Rhodes, Bale M. Swamy, Shashikala R. Inamdar

Pages: 2803-2810 Published online on: 03 April 2017
Article

HBx represses RIZ1 expression by DNA methyltransferase 1 involvement in decreased miR-152 in hepatocellular carcinoma

Zhujiang Zhao, Ying Hu, Xiaohui Shen, Yingbin Lao, Lihua Zhang, Xuemei Qiu, Jiaojiao Hu, Pihai Gong, He Cui, Sen Lu, Ying Zheng, Menghan Zhou, Hong Fan

Pages: 2811-2818 Published online on: 21 March 2017
Article

The specific killing effect of matrine on castration-resistant prostate cancer cells by targeting the Akt/FoxO3a signaling pathway Corrigendum in /10.3892/or.2020.7784

Shoumin Bai, Ting Chen, Xiaoli Yu, Ming Luo, Xianju Chen, Chunhao Lin, Yiming Lai, Hai Huang

Pages: 2819-2828 Published online on: 16 March 2017
Article

Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells

Sai Wu, Yan Zhou, Gaoxiang Yang, Hua Tian, Yang Geng, Yabin Hu, Kai Lin, Wei Wu

Pages: 2829-2838 Published online on: 06 April 2017
Article

SPAG6 regulates cell apoptosis through the TRAIL signal pathway in myelodysplastic syndromes

Xinxin Li, Bihui Yang, Li Wang, Liping Chen, Xiaohua Luo, Lin Liu

Pages: 2839-2846 Published online on: 31 March 2017
Article

Nobiletin inhibits invasion via inhibiting AKT/GSK3β/β-catenin signaling pathway in Slug-expressing glioma cells

Xiang Zhang, Kebin Zheng, Chunhui Li, Yonghui Zhao, Heyang Li, Xuguang Liu, Yinbo Long, Junchao Yao

Pages: 2847-2856 Published online on: 23 March 2017
Article

P21 activated kinase 4 binds translation elongation factor eEF1A1 to promote gastric cancer cell migration and invasion

Xiang Li, Jiabin Li, Feng Li

Pages: 2857-2864 Published online on: 31 March 2017
Article

High ATP2A2 expression correlates with better prognosis of diffuse astrocytic tumor patients

Wei-Qing Li, Nan-Zhe Zhong, Jin He, Yi-Ming Li, Li-Jun Hou, Hui-Min Liu, Chun-Yan Xia, Liang-Zhe Wang, Yi-Cheng Lu

Pages: 2865-2874 Published online on: 24 March 2017
Article

Maspin suppresses growth, proliferation and invasion in cutaneous squamous cell carcinoma cells

Hong Zhu, Qing Mao, Weiwei Liu, Zhenhai Yang, Xiaoqing Jian, Le Qu, Chundi He

Pages: 2875-2882 Published online on: 11 April 2017
Article

Upregulated microRNA-429 inhibits the migration of HCC cells by targeting TRAF6 through the NF-κB pathway

Peng Wang, Jia Cao, Shihai Liu, Huazheng Pan, Xiangping Liu, Aihua Sui, Liping Wang, Ruyong Yao, Zimin Liu, Jun Liang

Pages: 2883-2890 Published online on: 15 March 2017
Article

Inactivation of EGFR/AKT signaling enhances TSA-induced ovarian cancer cell differentiation

Genbao Shao, Wensheng Lai, Xiaolei Wan, Jing Xue, Ye Wei, Jie Jin, Liuping Zhang, Qiong Lin, Qixiang Shao, Shengqiang Zou

Pages: 2891-2896 Published online on: 05 April 2017
Article

Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells

Shigeki Sumi, Naoki Umemura, Eiji Takayama, Emika Ohkoshi, Makoto Adachi, Masako Mizuno-Kamiya, Toshihiro Inagaki, Harumi Kawaki, Shinichiro Sumitomo, Nobuo Kondoh

Pages: 2897-2904 Published online on: 11 April 2017
Article

Differential effects of sulforaphane in regulation of angiogenesis in a co-culture model of endothelial cells and pericytes

Yichong Wang, Zhigang Zhou, Wei Wang, Ming Liu, Yongping Bao

Pages: 2905-2912 Published online on: 11 April 2017
Article

Inhibition of CCR7 promotes NF-κB-dependent apoptosis and suppresses epithelial-mesenchymal transition in non-small cell lung cancer

Lan Zhang, Xuyang Xiao, Hui An, Jian Wang, Yanmei Ma, Yi-Hua Qian

Pages: 2913-2919 Published online on: 23 March 2017
Article

Inverse relationship between insulin receptor expression and progression in renal cell carcinoma

Makoto Takahashi, Takamitsu Inoue, Mingguo Huang, Kazuyuki Numakura, Hiroshi Tsuruta, Mitsuru Saito, Atsushi Maeno, Eijiro Nakamura, Shintaro Narita, Norihiko Tsuchiya, Tomonori Habuchi

Pages: 2929-2941 Published online on: 05 April 2017
Article

A novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cell line Eca-109/5-FU with significant drug resistance-related characteristics

Chi Zhang, Qunfeng Ma, Yinan Shi, Xue Li, Ming Wang, Junfeng Wang, Jianlin Ge, Zhinan Chen, Ziling Wang, Hong Jiang

Pages: 2942-2954 Published online on: 31 March 2017
Article

High expression of atonal homolog 8 predicts a poor clinical outcome in patients with colorectal cancer and contributes to tumor progression

Mengsi Ye, Yun He, Hao Lin, Shouxing Yang, Yuhui Zhou, Lingling Zhou, Jinwei Zhong, Guangrong Lu, Jihang Zheng, Zhan-Xiong Xue, Zhen-Zhai Cai

Pages: 2955-2963 Published online on: 05 April 2017
Article

Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness

Naoki Nanashima, Kayo Horie, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida

Pages: 2964-2970 Published online on: 11 April 2017
Article

Overexpression of RIP140 suppresses the malignant potential of hepatocellular carcinoma by inhibiting NF‑κB‑mediated alternative polarization of macrophages

Ying-Chun Hu, Zhu-Jun Yi, Yun Zhou, Pei-Zhi Li, Zuo-Jin Liu, Shi-Gang Duan, Jian-Ping Gong

Pages: 2971-2979 Published online on: 05 April 2017
Article

ROCK inhibition as a potential therapeutic target involved in apoptosis in hemangioma

Ming-Ke Qiu, Shu-Qing Wang, Chang Pan, Yang Wang, Zhi-Wei Quan, Ying-Bin Liu, Jing-Min Ou

Pages: 2987-2993 Published online on: 21 March 2017
Article

Contribution of caspase-independent pathway to apoptosis in malignant glioma induced by carbon ion beams

Luwei Zhang, Jiawei Yan, Yang Liu, Qiuyue Zhao, Cuixia Di, Sun Chao, Li Jie, Yuanyuan Liu, Hong Zhang

Pages: 2994-3000 Published online on: 24 March 2017
Article

Role of the cystathionine β-synthase/H2S system in liver cancer cells and the inhibitory effect of quinolone-indolone conjugate QIC2 on the system

Huina Jia, Juan Ye, Jing You, Xiaoyan Shi, Wenyi Kang, Tianxiao Wang

Pages: 3001-3009 Published online on: 17 March 2017
Article

Hypoxia-induced miR-210 promoter demethylation enhances proliferation, autophagy and angiogenesis of schwannoma cells

Zhengguang Wang, Mingsi Deng, Zhendong Liu, Song Wu

Pages: 3010-3018 Published online on: 16 March 2017
Article

Direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of PANC-1 cells

Jianhui Duan, Yilixiati Xiaokaiti, Shengjun Fan, Yan Pan, Xin Li, Xuejun Li

Pages: 3019-3025 Published online on: 21 March 2017
Article

Overexpression of p53 protein is a marker of poor prognosis in Mexican women with breast cancer

Jisela Dimas-González, Vilma Maldonado-Lagunas, José Díaz‑Chávez, María Eugenia López-Arellano, José Muñoz-Camacho, Marco Antonio Terán-Porcayo, Alfredo Lagunas-Martínez

Pages: 3026-3036 Published online on: 05 April 2017
Article

Recombinant adenovirus of SEA and CD80 genes driven by MMRE and mouse TERT promoter induce effective antitumor immune responses against different types of tumor cells in vitro and in vivo

Shao-Yan Si, Jun-Li Liu, Jun-Lian Liu, Bing-Xin Xu, Jian-Zhong Li, Ya-Ya Qin, Shu-Jun Song

Pages: 3037-3045 Published online on: 06 April 2017
Article

BAMBI overexpression together with β-sitosterol ameliorates NSCLC via inhibiting autophagy and inactivating TGF-β/Smad2/3 pathway

Xingchun Wang, Minjie Li, Mengyao Hu, Ping Wei, Wei Zhu

Pages: 3046-3054 Published online on: 15 March 2017
Article

Triple-negative breast cancer: New therapeutic options via signalling transduction cascades

Ulrich Andergassen, Alexandra C. Kölbl, Jan-Niclas Mumm, Sven Mahner, Udo Jeschke

Pages: 3055-3060 Published online on: 16 March 2017
Article

Transcriptional activation of PD-L1 by Sox2 contributes to the proliferation of hepatocellular carcinoma cells

Feng Zhong, Xinsheng Cheng, Shibo Sun, Jie Zhou

Pages: 3061-3067 Published online on: 23 March 2017
Article

CUTL1 induces epithelial-mesenchymal transition in non-small cell lung cancer

Junfeng Wang, Yanbo Wang, Dawei Sun, Fenghai Ren, Sainan Pang, Shidong Xu

Pages: 3068-3074 Published online on: 11 April 2017
Article

125I seed irradiation induces apoptosis and inhibits angiogenesis by decreasing HIF-1α and VEGF expression in lung carcinoma xenografts

Gui-Ling Xiang, Xin-Hong Zhu, Cun-Zhi Lin, Li-Jun Wang, Yong Sun, Yi-Wei Cao, Fang-Fang Wang

Pages: 3075-3083 Published online on: 23 March 2017
Article

Cross-validation of genes potentially associated with overall survival and drug resistance in ovarian cancer

Yutao Gao, Xia Liu, Ting Li, Luwei Wei, Antai Yang, Yi Lu, Jian Zhang, Li Li, Sumei Wang, Fuqiang Yin

Pages: 3084-3092 Published online on: 27 March 2017
Article

Long non-coding RNA MEG3 induces cell apoptosis in esophageal cancer through endoplasmic reticulum stress

Zhen-Lun Huang, Rui-Pei Chen, Xiao-Tao Zhou, Hao-Lian Zhan, Min-Min Hu, Bin Liu, Guan-Di Wu, Ling-Fei Wu

Pages: 3093-3099 Published online on: 11 April 2017
Article

Optimal method for quantitative detection of plasma EGFR T790M mutation using droplet digital PCR system

Ken Suzawa, Hiromasa Yamamoto, Kadoaki Ohashi, Shinsuke Hashida, Shuta Tomida, Toshio Kubo, Yuho Maki, Junichi Soh, Kazunori Tsukuda, Katsuyuki Kiura, Shinichiro Miyoshi, Shinichi Toyooka

Pages: 3100-3106 Published online on: 11 April 2017
Article

Assessment of Th17 lymphocytes and cytokine IL‑17A in epithelial ovarian tumors

Izabela Winkler, Maria Pyszniak, Katarzyna Pogoda, Andrzej Semczuk, Marek Gogacz, Paweł Miotla, Aneta Adamiak, Dorota Darmochwal‑Kolarz, Tomasz Rechberger, Jacek Tabarkiewicz

Pages: 3107-3115 Published online on: 06 April 2017
Article

miR-107 functions as a tumor suppressor in human esophageal squamous cell carcinoma and targets Cdc42

Priyanka Sharma, Neeru Saini, Rinu Sharma

Pages: 3116-3127 Published online on: 03 April 2017
Article

Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor

Hideyoshi Kawasaki, Takuya Saotome, Tatsuya Usui, Takashi Ohama, Koichi Sato

Pages: 3128-3136 Published online on: 22 March 2017
Article

Induction of galectin-1 by TLR-dependent PI3K activation enhances epithelial-mesenchymal transition of metastatic ovarian cancer cells

Ga Bin Park, Yoon Hee Chung, Daejin Kim

Pages: 3137-3145 Published online on: 27 March 2017
Journal Cover

May-2017
Volume 37 Issue 5

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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