|
1
|
Bao H, Liu P, Jiang K, Zhang X, Xie L,
Wang Z and Gong P: Huaier polysaccharide induces apoptosis in
hepatocellular carcinoma cells through p38 MAPK. Oncol Lett.
12:1058–1066. 2016.PubMed/NCBI
|
|
2
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Signoriello S, Annunziata A, Lama N,
Signoriello G, Chiodini P, De Sio I, Daniele B, Di Costanzo GG,
Calise F, Olivieri G, et al: Survival after locoregional treatments
for hepatocellular carcinoma: A cohort study in real-world
patients. Sci World J. 2012:5647062012. View Article : Google Scholar
|
|
4
|
Chan SL and Yeo W: Targeted therapy of
hepatocellular carcinoma: Present and future. J Gastroenterol
Hepatol. 27:862–872. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Lu SC: Where are we in the chemoprevention
of hepatocellular carcinoma? Hepatology. 51:734–736.
2010.PubMed/NCBI
|
|
6
|
Wang X, Wang N, Cheung F, Lao L, Li C and
Feng Y: Chinese medicines for prevention and treatment of human
hepatocellular carcinoma: Current progress on pharmacological
actions and mechanisms. J Integr Med. 13:142–164. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li H, Miao Q, Xu CW, Huang JH, Zhou YF and
Wu MJ: OTX1 contributes to hepatocellular carcinoma progression by
regulation of ERK/MAPK pathway. J Korean Med Sci. 31:1215–1223.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Sepand MR, Ghahremani MH,
Razavi-Azarkhiavi K, Aghsami M, Rajabi J, Keshavarz-Bahaghighat H
and Soodi M: Ellagic acid confers protection against
gentamicin-induced oxidative damage, mitochondrial dysfunction and
apoptosis-related nephrotoxicity. J Pharm Pharmacol. 68:1222–1232.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zeng CC, Lai SH, Yao JH, Zhang C, Yin H,
Li W, Han BJ and Liu YJ: The induction of apoptosis in HepG-2 cells
by ruthenium(II) complexes through an intrinsic ROS-mediated
mitochondrial dysfunction pathway. Eur J Med Chem. 122:118–126.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Diao QX, Zhang JZ, Zhao T, Xue F, Gao F,
Ma SM and Wang Y: Vitamin E promotes breast cancer cell
proliferation by reducing ROS production and p53 expression. Eur
Rev Med Pharmacol Sci. 20:2710–2717. 2016.PubMed/NCBI
|
|
11
|
Zhu HJ, Wang DG, Yan J and Xu J:
Up-regulation of microRNA-135a protects against myocardial
ischemia/reperfusion injury by decreasing TXNIP expression in
diabetic mice. Am J Transl Res. 7:2661–2671. 2015.PubMed/NCBI
|
|
12
|
Hong K, Xu G, Grayson TB and Shalev A:
Cytokines regulate β-cell thioredoxin-interacting protein (TXNIP)
via distinct mechanisms and pathways. J Biol Chem. 291:8428–8439.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hong SY and Hagen T: 2-Deoxyglucose
induces the expression of thioredoxin interacting protein (TXNIP)
by increasing O-GlcNAcylation - Implications for targeting the
Warburg effect in cancer cells. Biochem Biophys Res Commun.
465:838–844. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen D, Dang BL, Huang JZ, Chen M, Wu D,
Xu ML, Li R and Yan GR: MiR-373 drives the
epithelial-to-mesenchymal transition and metastasis via the
miR-373-TXNIP-HIF1α-TWIST signaling axis in breast cancer.
Oncotarget. 6:32701–32712. 2015.PubMed/NCBI
|
|
15
|
Baldan F, Mio C, Lavarone E, Di Loreto C,
Puglisi F, Damante G and Puppin C: Epigenetic bivalent marking is
permissive to the synergy of HDAC and PARP inhibitors on TXNIP
expression in breast cancer cells. Oncol Rep. 33:2199–2206.
2015.PubMed/NCBI
|
|
16
|
Nie W, Huang W, Zhang W, Xu J, Song W,
Wang Y, Zhu A, Luo J, Huang G, Wang Y, et al: TXNIP interaction
with the Her-1/2 pathway contributes to overall survival in breast
cancer. Oncotarget. 6:3003–3012. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Morrison JA, Pike LA, Sams SB, Sharma V,
Zhou Q, Severson JJ, Tan AC, Wood WM and Haugen BR: Thioredoxin
interacting protein (TXNIP) is a novel tumor suppressor in thyroid
cancer. Mol Cancer. 13:622014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Filios SR, Xu G, Chen J, Hong K, Jing G
and Shalev A: MicroRNA-200 is induced by thioredoxin-interacting
protein and regulates Zeb1 protein signaling and beta cell
apoptosis. J Biol Chem. 289:36275–36283. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ho B, Huang G and Golubovskaya VM: Focal
adhesion kinase regulates expression of thioredoxin-interacting
protein (TXNIP) in cancer cells. Anticancer Agents Med Chem.
14:3–8. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu Y, Zhang JB, Qin Y, Wang W, Wei L,
Teng Y, Guo L, Zhang B, Lin Z, Liu J, et al: PROX1 promotes
hepatocellular carcinoma metastasis by way of up-regulating
hypoxia-inducible factor 1α expression and protein stability.
Hepatology. 58:692–705. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Nishiyama A, Matsui M, Iwata S, Hirota K,
Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y and Yodoi J:
Identification of thioredoxin-binding protein-2/vitamin D(3)
up-regulated protein 1 as a negative regulator of thioredoxin
function and expression. J Biol Chem. 274:21645–21650. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Welsh SJ, Bellamy WT, Briehl MM and Powis
G: The redox protein thioredoxin-1 (Trx-1) increases
hypoxia-inducible factor 1alpha protein expression: Trx-1
overexpression results in increased vascular endothelial growth
factor production and enhanced tumor angiogenesis. Cancer Res.
62:5089–5095. 2002.PubMed/NCBI
|
|
23
|
Saitoh M, Nishitoh H, Fujii M, Takeda K,
Tobiume K, Sawada Y, Kawabata M, Miyazono K and Ichijo H: Mammalian
thioredoxin is a direct inhibitor of apoptosis signal-regulating
kinase (ASK) 1. EMBO J. 17:2596–2606. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Liu Y and Min W: Thioredoxin promotes ASK1
ubiquitination and degradation to inhibit ASK1-mediated apoptosis
in a redox activity-independent manner. Circ Res. 90:1259–1266.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhou J, Bi C, Cheong LL, Mahara S, Liu SC,
Tay KG, Koh TL, Yu Q and Chng WJ: The histone methyltransferase
inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and
targets leukemia cells in AML. Blood. 118:2830–2839. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hirotsu C, Tufik S, Bergamaschi CT,
Tenorio NM, Araujo P and Andersen ML: Sleep pattern in an
experimental model of chronic kidney disease. Am J Physiol Renal
Physiol. 299:F1379–F1388. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Sheth SS, Bodnar JS, Ghazalpour A,
Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani
H and Lusis AJ: Hepatocellular carcinoma in Txnip-deficient mice.
Oncogene. 25:3528–3536. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Butler LM, Zhou X, Xu WS, Scher HI,
Rifkind RA, Marks PA and Richon VM: The histone deacetylase
inhibitor SAHA arrests cancer cell growth, up-regulates
thioredoxin-binding protein-2, and down-regulates thioredoxin. Proc
Natl Acad Sci USA. 99:pp. 11700–11705. 2002; View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Nishizawa K, Nishiyama H, Matsui Y,
Kobayashi T, Saito R, Kotani H, Masutani H, Oishi S, Toda Y, Fujii
N, et al: Thioredoxin-interacting protein suppresses bladder
carcinogenesis. Carcinogenesis. 32:1459–1466. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Fox JL and MacFarlane M: Targeting cell
death signalling in cancer: Minimising ‘Collateral damage’. Br J
Cancer. 115:5–11. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Matthews GM, Newbold A and Johnstone RW:
Intrinsic and extrinsic apoptotic pathway signaling as determinants
of histone deacetylase inhibitor antitumor activity. Adv Cancer
Res. 116:165–197. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wajant H: The Fas signaling pathway: More
than a paradigm. Science. 296:1635–1636. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Shimizu H, Banno Y, Sumi N, Naganawa T,
Kitajima Y and Nozawa Y: Activation of p38 mitogen-activated
protein kinase and caspases in UVB-induced apoptosis of human
keratinocyte HaCaT cells. J Invest Dermatol. 112:769–774. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wu YJ, Wong BS, Yea SH, Lu CI and Weng SH:
Sinularin induces apoptosis through mitochondria dysfunction and
inactivation of the pI3K/Akt/mTOR pathway in gastric carcinoma
cells. Mar Drugs. 14:142016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Zong WX, Rabinowitz JD and White E:
Mitochondria and Cancer. Mol Cell. 61:667–676. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Weinberg SE and Chandel NS: Targeting
mitochondria metabolism for cancer therapy. Nat Chem Biol. 11:9–15.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Byun HO, Kim HY, Lim JJ, Seo YH and Yoon
G: Mitochondrial dysfunction by complex II inhibition delays
overall cell cycle progression via reactive oxygen species
production. J Cell Biochem. 104:1747–1759. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Wang L, Zhang X, Cui G, Chan JY, Wang L,
Li C, Shan L, Xu C, Zhang Q, Wang Y, et al: A novel agent exerts
antitumor activity in breast cancer cells by targeting
mitochondrial complex II. Oncotarget. 7:32054–32064.
2016.PubMed/NCBI
|
|
39
|
Ralph SJ, Moreno-Sánchez R, Neuzil J and
Rodríguez-Enríquez S: Inhibitors of succinate: Quinone
reductase/Complex II regulate production of mitochondrial reactive
oxygen species and protect normal cells from ischemic damage but
induce specific cancer cell death. Pharm Res. 28:2695–2730. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zhang C, Jia X, Bao J, Chen S, Wang K,
Zhang Y, Li P, Wan JB, Su H, Wang Y, et al: Polyphyllin VII induces
apoptosis in HepG2 cells through ROS-mediated mitochondrial
dysfunction and MAPK pathways. BMC Complement Altern Med.
16:582016. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Takeda K, Matsuzawa A, Nishitoh H and
Ichijo H: Roles of MAPKKK ASK1 in stress-induced cell death. Cell
Struct Funct. 28:23–29. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Zebelo SA and Maffei ME: Role of early
signalling events in plant-insect interactions. J Exp Bot.
66:435–448. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Avisetti DR, Babu KS and Kalivendi SV:
Activation of p38/JNK pathway is responsible for embelin induced
apoptosis in lung cancer cells: Transitional role of reactive
oxygen species. PLoS One. 9:e870502014. View Article : Google Scholar : PubMed/NCBI
|
