Journal Articles

Preclinical studies for the combination of paclitaxel and curcumin in cancer therapy (Review)

Yumeng Wei, Xinlin Pu, Ling Zhao

Pages: 3159-3166 Published online on: 20 April 2017
Open Access

Cathepsin B expression in colorectal cancer in a Middle East population: Potential value as a tumor biomarker for late disease stages

Maha-Hamadien Abdulla, Mansoor-Ali Valli-Mohammed, Khayal Al-Khayal, Abdulmalik Al Shkieh, Ahmad Zubaidi, Rehan Ahmad, Khalid Al-Saleh, Omar Al-Obeed, James McKerrow

Pages: 3175-3180 Published online on: 18 April 2017
Open Access

Identification of SETD2-NF1 fusion gene in a pediatric spindle cell tumor with the chromosomal translocation t(3;17)(p21;q12)

Ioannis Panagopoulos, Ludmila Gorunova, Ingvild Lobmaier, Bodil Bjerkehagen, Sverre Heim

Pages: 3181-3188 Published online on: 04 May 2017
Open Access

CD24 expression is a marker for predicting clinical outcome and regulates the epithelial-mesenchymal transition in ovarian cancer via both the Akt and ERK pathways

Kiyoko Nakamura, Yoshito Terai, Akiko Tanabe, Yoshihiro J. Ono, Masami Hayashi, Kazuya Maeda, Satoe Fujiwara, Keisuke Ashihara, Michihiko Nakamura, Yoshimichi Tanaka, Tomohito Tanaka, Satoshi Tsunetoh, Hiroshi Sasaki, Masahide Ohmichi

Pages: 3189-3200 Published online on: 19 April 2017
Open Access

β-catenin induces expression of prohibitin gene in acute leukemic cells

Dong Min Kim, Hanbit Jang, Myung Geun Shin, Jeong-Hoon Kim, Sang Mo Shin, Sang-Hyun Min, Il-Chul Kim

Pages: 3201-3208 Published online on: 25 April 2017
Open Access

RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cells

Binbin Yin, Zhenping Liu, Yiyun Wang, Xuchu Wang, Weiwei Liu, Pan Yu, Xiuzhi Duan, Chunhua Liu, Yuhua Chen, Yurong Zhang, Xiaoyan Pan, Hangping Yao, Zhaoping Liao, Zhihua Tao

Pages: 3209-3218 Published online on: 19 April 2017
Open Access

Comparison of three different methods for the detection of circulating tumor cells in mice with lung metastasis

Weifeng Xu, Bing Wu, Lengxi Fu, Junying Chen, Zeng Wang, Fei Huang, Jinrong Chen, Mei Zhang, Zhenhuan Zhang, Jingan Lin, Ruilong Lan, Ruiqing Chen, Wei Chen, Long Chen, Jinsheng Hong, Weijian Zhang, Yuxiong Ding, Paul Okunieff, Jianhua Lin, Lurong Zhang

Pages: 3219-3226 Published online on: 02 May 2017
Open Access

MicroRNA-1299 is a negative regulator of STAT3 in colon cancer

Yong Wang, Zhi Lu, Ningning Wang, Man Zhang, Xiandong Zeng, Wei Zhao

Pages: 3227-3234 Published online on: 26 April 2017
Open Access

Identification and expression of MMSA-8, and its clinical significance in multiple myeloma

Rui He, Nan Yang, Pengyu Zhang, Jie Liu, Junhui Li, Fulin Zhou, Wanggang Zhang

Pages: 3235-3243 Published online on: 28 April 2017
Open Access

miR-138 suppresses the proliferation, metastasis and autophagy of non-small cell lung cancer by targeting Sirt1

Zaiting Ye, Bingmu Fang, Jiongwei Pan, Ning Zhang, Jinwei Huang, Congying Xie, Tianzheng Lou, Zhuo Cao

Pages: 3244-3252 Published online on: 03 May 2017

Association of long-chain acyl-coenzyme A synthetase 5 expression in human breast cancer by estrogen receptor status and its clinical significance

Meng-Chi Yen, Jung-Yu Kan, Chia-Jung Hsieh, Po-Lin Kuo, Ming-Feng Hou, Ya-Ling Hsu

Pages: 3253-3260 Published online on: 28 April 2017

AXL and GAS6 co-expression in lung adenocarcinoma as a prognostic classifier

Masahiro Seike, Cheol-Hong Kim, Fenfei Zou, Rintaro Noro, Mika Chiba, Arimi Ishikawa, Shinobu Κunugi, Kaoru Kubota, Akihiko Gemma

Pages: 3261-3269 Published online on: 21 April 2017

Silibinin downregulates MMP2 expression via Jak2/STAT3 pathway and inhibits the migration and invasive potential in MDA-MB-231 cells

Hyo Joo Byun, Pramod Darvin, Dong Young Kang, Nipin Sp, Youn Hee Joung, Jong Hwan Park, Sun Jin Kim, Young Mok Yang

Pages: 3270-3278 Published online on: 19 April 2017

CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang

Pages: 3279-3286 Published online on: 25 April 2017

Modified Panax ginseng extract regulates autophagy by AMPK signaling in A549 human lung cancer cells

Hwa-Seung Yoo, Jung Min Kim, Eunbi Jo, Chong-Kwan Cho, Seung-Yeul Lee, Hwan Su Kang, Min-Goo Lee, Pei-Ying Yang, Ik-Soon Jang

Pages: 3287-3296 Published online on: 20 April 2017

A nine-miRNA signature as a potential diagnostic marker for breast carcinoma: An integrated study of 1,110 cases

Dan-Dan Xiong, Jun Lv, Kang-Lai Wei, Zhen-Bo Feng, Ji-Tian Chen, Ke-Cheng Liu, Gang Chen, Dian-Zhong Luo

Pages: 3297-3304 Published online on: 25 April 2017

MicroRNA-15b promotes proliferation and invasion of non‑small cell lung carcinoma cells by directly targeting TIMP2

Haowen Wang, Yu Zhan, Jingjing Jin, Chunhong Zhang, Wenfeng Li

Pages: 3305-3312 Published online on: 26 April 2017

Novel role of semaphorin 3A in the growth and progression of hepatocellular carcinoma

Xuedong Li, Qing Chen, Dan Yin, Shiming Shi, Lei Yu, Shaolai Zhou, Erbao Chen, Zhengjun Zhou, Yinghong Shi, Jia Fan, Jian Zhou, Zhi Dai

Pages: 3313-3320 Published online on: 02 May 2017

Salinomycin induces endoplasmic reticulum stress‑mediated autophagy and apoptosis through generation of reactive oxygen species in human glioma U87MG cells

Sun-Nyoung Yu, Sang-Hun Kim, Kwang-Youn Kim, Jae-Hoon Ji, Young-Kyo Seo, Hak Sun Yu, Soon-Cheol Ahn

Pages: 3321-3328 Published online on: 02 May 2017

Low-dose paclitaxel suppresses the induction of M2 macrophages in gastric cancer

Takahisa Yamaguchi, Sachio Fushida, Yasuhiko Yamamoto, Tomoya Tsukada, Jun Kinoshita, Katsunobu Oyama, Tomoharu Miyashita, Hidehiro Tajima, Itasu Ninomiya, Seiichi Munesue, Ai Harashima, Shinichi Harada, Hiroshi Yamamoto, Tetsuo Ohta

Pages: 3341-3350 Published online on: 19 April 2017

Evaluation of expression of cancer stem cell markers and fusion gene in synovial sarcoma: Insights into histogenesis and pathogenesis

Yang Zhou, Dongdong Chen, Yan Qi, Ruixue Liu, Shugang Li, Hong Zou, Jiaojiao Lan, Xinxin Ju, Jinfang Jiang, Weihua Liang, Yaoyuan Shen, Lijuan Pang, Feng Li

Pages: 3351-3360 Published online on: 02 May 2017

Knockdown of CREB1 inhibits tumor growth of human gastric cancer in vitro and in vivo

Min Rao, Yonggang Zhu, Xiaoxia Cong, Qianxun Li

Pages: 3361-3368 Published online on: 11 May 2017

TXNIP overexpression suppresses proliferation and induces apoptosis in SMMC7221 cells through ROS generation and MAPK pathway activation

Jian Li, Zhongyi Yue, Wancheng Xiong, Peisheng Sun, Kun You, Jianguo Wang

Pages: 3369-3376 Published online on: 18 April 2017

Inhibition of ATR potentiates the cytotoxic effect of gemcitabine on pancreatic cancer cells through enhancement of DNA damage and abrogation of ribonucleotide reductase induction by gemcitabine

Shuang Liu, Yubin Ge, Tingting Wang, Holly Edwards, Qihang Ren, Yiqun Jiang, Chengshi Quan, Guan Wang

Pages: 3377-3386 Published online on: 19 April 2017

AdipoR1-mediated miR-3908 inhibits glioblastoma tumorigenicity through downregulation of STAT2 associated with the AMPK/SIRT1 pathway

Xiangming Liu, Jinglong Chen, Jinqian Zhang

Pages: 3387-3396 Published online on: 20 April 2017

Imperatorin efficiently blocks TNF-α-mediated activation of ROS/PI3K/Akt/NF-κB pathway

Ke Si Wang, Ying Lv, Zhe Wang, Juan Ma, Chunliu Mi, Xuezheng Li, Guang Hua Xu, Lian Xun Piao, Sheng Zhe Zheng, Xuejun Jin

Pages: 3397-3404 Published online on: 19 April 2017

Nifuroxazide prompts antitumor immune response of TCL-loaded DC in mice with orthotopically-implanted hepatocarcinoma

Tiesuo Zhao, Huijie Jia, Qian Cheng, Yali Xiao, Minming Li, Wenjing Ren, Chen Li, Yuchen Feng, Zhiwei Feng, Hui Wang, Junnian Zheng

Pages: 3405-3414 Published online on: 05 May 2017

miR-944 inhibits cell migration and invasion by targeting MACC1 in colorectal cancer

Liqiang Wen, Yingru Li, Zhipeng Jiang, Yuchao Zhang, Bin Yang, Fanghai Han

Pages: 3415-3422 Published online on: 28 April 2017

Plumbagin enhances TRAIL-induced apoptosis of human leukemic Kasumi‑1 cells through upregulation of TRAIL death receptor expression, activation of caspase-8 and inhibition of cFLIP

Xiaoyang Kong, Jing Luo, Tongpeng Xu, Yunjiao Zhou, Zengkai Pan, Yinghua Xie, Limin Zhao, Yingting Lu, Xiyao Han, Zhixiong Li, Ligen Liu

Pages: 3423-3432 Published online on: 04 May 2017

SUVmax of 18F-FDG PET/CT correlates to expression of major chemotherapy-related tumor markers and serum tumor markers in gastric adenocarcinoma patients

Lu Bai, Chi-Hua Guo, Yan Zhao, Jun-Gang Gao, Miao Li, Cong Shen, You-Min Guo, Xiao-Yi Duan

Pages: 3433-3440 Published online on: 05 May 2017

CpG oligodeoxynucleotides augment antitumor efficacy of folate receptor α based DNA vaccine

Zheng Qiu, Lijun Xing, Xueqing Zhang, Xu Qiang, Yifeng Xu, Mei Zhang, Zhengpin Zhou, Juan Zhang, Fang Zhang, Min Wang

Pages: 3441-3448 Published online on: 08 May 2017

SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways

Fang Tang, Pengchao Hu, Zetian Yang, Chao Xue, Jun Gong, Shaoxing Sun, Liu Shi, Shimin Zhang, Zhenzhen Li, Chunxu Yang, Junhong Zhang, Conghua Xie

Pages: 3449-3458 Published online on: 10 May 2017

Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells

Wei Li, Ying Zhou, Jin Yang, Haining Li, Huanhuan Zhang, Ping Zheng

Pages: 3459-3466 Published online on: 11 May 2017

Prognostic significance of altered miRNA expression in whole blood of OSCC patients

Jutta Ries, Christoph Baran, Falk Wehrhan, Manuel Weber, Friedrich W. Neukam, Andrea Krautheim-Zenk, Emeka Nkenke

Pages: 3467-3474 Published online on: 11 May 2017

Effect of miR-1244 on cisplatin-treated non-small cell lung cancer via MEF2D expression

Guang-Jian Li, Guang-Qiang Zhao, Jia-Peng Yang, Yong-Chun Zhou, Kai-Yun Yang, Yu-Jie Lei, Yun-Chao Huang

Pages: 3475-3483 Published online on: 04 May 2017

CENP-H regulates the cell growth of human hepatocellular carcinoma cells through the mitochondrial apoptotic pathway

Guifang Lu, Helei Hou, Xinlan Lu, Xiquan Ke, Xin Wang, Dan Zhang, Yan Zhao, Jun Zhang, Mudan Ren, Shuixiang He

Pages: 3484-3492 Published online on: 26 April 2017

Exploration of miR-1202 and miR-196a in human endometrial cancer based on high throughout gene screening analysis

Hong Chen, Yujuan Fan, Wensheng Xu, Junying Chen, Yugang Meng, Di Fang, Jingran Wang

Pages: 3493-3501 Published online on: 24 April 2017

MicroRNA-379-5p plays a tumor-suppressive role in human bladder cancer growth and metastasis by directly targeting MDM2

Deyao Wu, Xiaobing Niu, Jun Tao, Pengchao Li, Qiang Lu, Aiming Xu, Wei Chen, Zengjun Wang

Pages: 3502-3508 Published online on: 27 April 2017

Effective cytotoxic activity of OSW-1 on colon cancer by inducing apoptosis in vitro and in vivo

Yanhong Zhang, Fengqi Fang, Kai Fan, Yanli Zhang, Jie Zhang, Huishu Guo, Peiyao Yu, Jianmei Ma

Pages: 3509-3519 Published online on: 19 April 2017

MicroRNA-26a inhibits proliferation and metastasis of human hepatocellular carcinoma by regulating DNMT3B-MEG3 axis

Yarui Li, Mudan Ren, Yan Zhao, Xinlan Lu, Mengyao Wang, Junbi Hu, Guifang Lu, Shuixiang He

Pages: 3527-3535 Published online on: 19 April 2017

PRKDC regulates chemosensitivity and is a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients

Gang Sun, Le Yang, Chao Dong, Bin Ma, Meihui Shan, Binlin Ma

Pages: 3536-3542 Published online on: 09 May 2017

Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of lung cancer

Yanqiu Zhang, Jing Sui, Xian Shen, Chengyun Li, Wenzhuo Yao, Weiwei Hong, Hui Peng, Yuepu Pu, Lihong Yin, Geyu Liang

Pages: 3543-3553 Published online on: 28 April 2017

miR‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker

Wenjun Liu, Kai Qian, Xing Wei, Haijun Deng, Bei Zhao, Qing Chen, Jinqian Zhang, Hao Liu

Pages: 3554-3564 Published online on: 20 April 2017

CRISPR/Cas9-mediated genome engineering of CXCR4 decreases the malignancy of hepatocellular carcinoma cells in vitro and in vivo

Xiaoli Wang, Wenmei Zhang, Yan Ding, Xingrong Guo, Yahong Yuan, Dongsheng Li

Pages: 3565-3571 Published online on: 25 April 2017

Loss of Reelin suppresses cell survival and mobility in non-Hodgkin lymphoma

Aixia Dou, Zhilun Wang, Ni Zhang, Junli Liu

Pages: 3572-3580 Published online on: 04 May 2017

Demethylation of miR-495 inhibits cell proliferation, migration and promotes apoptosis by targeting STAT-3 in breast cancer

Yi Chen, Donglin Luo, Wuguo Tian, Zhirong Li, Xiaohua Zhang

Pages: 3581-3589 Published online on: 03 May 2017

TRIM28 knockdown increases sensitivity to etoposide by upregulating E2F1 in non-small cell lung cancer

Lei Liu, Lijun Xiao, Xiujun Liang, Long Chen, Luyang Cheng, Lei Zhang, Xiaoguang Wu, Qian Xu, Chunhu Ma

Pages: 3597-3605 Published online on: 11 May 2017

Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells

Sheau-Yun Yuan, Ming-Yuh Shiau, Yen-Chuan Ou, Yu-Chia Huang, Cheng-Che Chen, Chen-Li Cheng, Kun-Yuan Chiu, Shian-Shiang Wang, Kan-Jen Tsai

Pages: 3606-3616 Published online on: 27 April 2017

UVA-induced upregulation of progerin suppresses 53BP1‑mediated NHEJ DSB repair in human keratinocytes via progerin-lamin A complex formation

Xin Huang, Yun Pan, Di Cao, Sheng Fang, Kun Huang, Jin Chen, Aijun Chen

Pages: 3617-3624 Published online on: 26 April 2017

Time- and oxygen-dependent expression and regulation of NDRG1 in human brain cancer cells

Harun Muayad Said, Roghaiyeh Safari, Ghada Al-Kafaji, Ralf-Ingo Ernestus, Mario Löhr, Astrid Katzer, Michael Flentje, Carsten Hagemann

Pages: 3625-3634 Published online on: 03 May 2017

Marine actinomycete crude extracts with potent TRAIL-resistance overcoming activity against breast cancer cells

Mohammed I.Y. Elmallah, Olivier Micheau, Mennat Allah G. Eid, Ali M.S. Hebishy, Mohamed S. Abdelfattah

Pages: 3635-3642 Published online on: 21 April 2017

Annexin A2 inhibition suppresses ovarian cancer progression via regulating β-catenin/EMT

Yan Liu, Hongyu Li, Zhenying Ban, Manman Nai, Li Yang, Yannan Chen, Yiming Xu

Pages: 3643-3650 Published online on: 18 April 2017

Calpain and AR-V7: Two potential therapeutic targets to overcome acquired docetaxel resistance in castration-resistant prostate cancer cells

Lei Liu, Ning Lou, Xiang Li, Guanghua Xu, Hailong Ruan, Wen Xiao, Bin Qiu, Lin Bao, Changfei Yuan, Xinmian Huang, Keshan Wang, Qi Cao, Ke Chen, Hongmei Yang, Xiaoping Zhang

Pages: 3651-3659 Published online on: 04 May 2017

Sulforaphane sensitizes human cholangiocarcinoma to cisplatin via the downregulation of anti-apoptotic proteins

Rokas Račkauskas, Dachen Zhou, Simonas Ūselis, Kęstutis Strupas, Ingrid Herr, Peter Schemmer

Pages: 3660-3666 Published online on: 03 May 2017

Livin enhances chemoresistance in head and neck squamous cell carcinoma

Tae Mi Yoon, Sun-Ae Kim, Dong Hoon Lee, Joon Kyoo Lee, Young-Lan Park, Kyung-Hwa Lee, Ik-Joo Chung, Young-Eun Joo, Sang Chul Lim

Pages: 3667-3673 Published online on: 19 April 2017

Migration of oral squamous cell carcinoma cells are induced by HGF/c-Met signalling via lamellipodia and filopodia formation

Hiroki Yasui, Yuichi Ohnishi, Masahiro Nakajima, Masami Nozaki

Pages: 3674-3680 Published online on: 19 April 2017

Modulation of MMP-2 and -9 secretion by cytokines, inducers and inhibitors in human melanoma A-2058 cells

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath

Pages: 3681-3687 Published online on: 24 April 2017

Optimization of antitumor treatment conditions for transcutaneous CO2 application: An in vivo study

Takeshi Ueha, Teruya Kawamoto, Yasuo Onishi, Risa Harada, Masaya Minoda, Mitsunori Toda, Hitomi Hara, Naomasa Fukase, Masahiro Kurosaka, Ryosuke Kuroda, Toshihiro Akisue, Yoshitada Sakai

Pages: 3688-3694 Published online on: 20 April 2017

Chloroform fraction of Scutellaria barbata D. Don inhibits the growth of colorectal cancer cells by activating miR‑34a

Ling Zhang, Yi Fang, Jian-Yu Feng, Qiao-Yan Cai, Li-Hui Wei, Shan Lin, Jun Peng

Pages: 3695-3701 Published online on: 04 May 2017
Journal Cover

June-2017
Volume 37 Issue 6

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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