|
1
|
Feagins LA, Souza RF and Spechler SJ:
Carcinogenesis in IBD: Potential targets for the prevention of
colorectal cancer. Nat Rev Gastroenterol Hepatol. 6:297–305. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lamprecht SA and Lipkin M: Chemoprevention
of colon cancer by calcium, vitamin D and folate: Molecular
mechanisms. Nat Rev Cancer. 3:601–614. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Li Y, Zhao Z, Xu C, Zhou Z, Zhu Z and You
T: HMGA2 induces transcription factor Slug expression to promote
epithelial-to-mesenchymal transition and contributes to colon
cancer progression. Cancer Lett. 355:130–140. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zhao Y, Zhang W, Guo Z, Ma F, Wu Y, Bai Y,
Gong W, Chen Y, Cheng T, Zhi F, et al: Inhibition of the
transcription factor Sp1 suppresses colon cancer stem cell growth
and induces apoptosis in vitro and in nude mouse xenografts.
Oncol Rep. 30:1782–1792. 2013.PubMed/NCBI
|
|
5
|
Shie JL, Chen ZY, Fu M, Pestell RG and
Tseng CC: Gut-enriched Krüppel-like factor represses cyclin D1
promoter activity through Sp1 motif. Nucleic Acids Res.
28:2969–2976. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Shen L, Qu X, Ma Y, Zheng J, Chu D, Liu B,
Li X, Wang M, Xu C, Liu N, et al: Tumor suppressor NDRG2 tips the
balance of oncogenic TGF-β via EMT inhibition in colorectal cancer.
Oncogenesis. 3:e862014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Deng Y, Yao L, Chau L, Ng SS, Peng Y, Liu
X, Au WS, Wang J, Li F, Ji S, et al: N-Myc downstream-regulated
gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int J
Cancer. 106:342–347. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Xu X, Li J, Sun X, Guo Y, Chu D, Wei L, Li
X, Yang G, Liu X, Yao L, et al: Tumor suppressor NDRG2 inhibits
glycolysis and glutaminolysis in colorectal cancer cells by
repressing c-Myc expression. Oncotarget. 6:26161–26176. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Liu N, Wang L, Li X, Yang Q, Liu X, Zhang
J, Zhang J, Wu Y, Ji S, Zhang Y, et al: N-Myc downstream-regulated
gene 2 is involved in p53-mediated apoptosis. Nucleic Acids Res.
36:5335–5349. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Liu N, Wang L, Liu X, Yang Q, Zhang J,
Zhang W, Wu Y, Shen L, Zhang Y, Yang A, et al: Promoter
methylation, mutation, and genomic deletion are involved in the
decreased NDRG2 expression levels in several cancer cell lines.
Biochem Biophys Res Commun. 358:164–169. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wang L, Liu N, Yao L, Li F, Zhang J, Deng
Y, Liu J, Ji S, Yang A, Han H, et al: NDRG2 is a new HIF-1 target
gene necessary for hypoxia-induced apoptosis in A549 cells. Cell
Physiol Biochem. 21:239–250. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zhang J, Li F, Liu X, Shen L, Liu J, Su J,
Zhang W, Deng Y, Wang L, Liu N, et al: The repression of human
differentiation-related gene NDRG2 expression by Myc via
Miz-1-dependent interaction with the NDRG2 core promoter. J Biol
Chem. 281:39159–39168. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Majors BS, Chiang GG and Betenbaugh MJ:
Protein and genome evolution in Mammalian cells for biotechnology
applications. Mol Biotechnol. 42:216–223. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Consortium EP: ENCODE Project Consortium:
An integrated encyclopedia of DNA elements in the human genome.
Nature. 489:57–74. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Svensson E, Vidovic K, Olofsson T,
Vallon-Christersson J, Borg A and Gullberg U: The Wilms' tumor gene
1 (WT1) induces expression of the N-myc downstream regulated gene 2
(NDRG2). DNA Cell Biol. 26:589–597. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yu T, Chen X, Zhang W, Li J, Xu R, Wang
TC, Ai W and Liu C: Krüppel-like factor 4 regulates intestinal
epithelial cell morphology and polarity. PLoS One. 7:e324922012.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Tabuchi Y, Takasaki I, Doi T, Ishii Y,
Sakai H and Kondo T: Genetic networks responsive to sodium butyrate
in colonic epithelial cells. FEBS Lett. 580:3035–3041. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Li D, Mei H, Pu J, Xiang X, Zhao X, Qu H,
Huang K, Zheng L and Tong Q: Intelectin 1 suppresses the growth,
invasion and metastasis of neuroblastoma cells through
up-regulation of N-myc downstream regulated gene 2. Mol Cancer.
14:472015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Adam PJ, Regan CP, Hautmann MB and Owens
GK: Positive- and negative-acting Kruppel-like transcription
factors bind a transforming growth factor beta control element
required for expression of the smooth muscle cell differentiation
marker SM22alpha in vivo. J Biol Chem. 275:37798–37806. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Bourillot PY and Savatier P: Krüppel-like
transcription factors and control of pluripotency. BMC Biol.
8:1252010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Pearson R, Fleetwood J, Eaton S, Crossley
M and Bao S: Krüppel-like transcription factors: A functional
family. Int J Biochem Cell Biol. 40:1996–2001. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yamada T, Park CS, Mamonkin M and
Lacorazza HD: Transcription factor ELF4 controls the proliferation
and homing of CD8+ T cells via the Krüppel-like factors
KLF4 and KLF2. Nat Immunol. 10:618–626. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Yet SF, McA'Nulty MM, Folta SC, Yen HW,
Yoshizumi M, Hsieh CM, Layne MD, Chin MT, Wang H, Perrella MA, et
al: Human EZF, a Krüppel-like zinc finger protein, is expressed in
vascular endothelial cells and contains transcriptional activation
and repression domains. J Biol Chem. 273:1026–1031. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Katz JP, Perreault N, Goldstein BG, Lee
CS, Labosky PA, Yang VW and Kaestner KH: The zinc-finger
transcription factor Klf4 is required for terminal differentiation
of goblet cells in the colon. Development. 129:2619–2628.
2002.PubMed/NCBI
|
|
25
|
Yu F, Li J, Chen H, Fu J, Ray S, Huang S,
Zheng H and Ai W: Kruppel-like factor 4 (KLF4) is required for
maintenance of breast cancer stem cells and for cell migration and
invasion. Oncogene. 30:2161–2172. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Li T, Lu H, Shen C, Lahiri SK, Wason MS,
Mukherjee D, Yu L and Zhao J: Identification of epithelial stromal
interaction 1 as a novel effector downstream of Krüppel-like factor
8 in breast cancer invasion and metastasis. Oncogene. 33:4746–4755.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Shum CK, Lau ST, Tsoi LL, Chan LK, Yam JW,
Ohira M, Nakagawara A, Tam PK and Ngan ES: Krüppel-like factor 4
(KLF4) suppresses neuroblastoma cell growth and determines
non-tumorigenic lineage differentiation. Oncogene. 32:4086–4099.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhang L, Wali A, Ramana CV and Rishi AK:
Cell growth inhibition by okadaic acid involves gut-enriched
Kruppel-like factor mediated enhanced expression of c-Myc. Cancer
Res. 67:10198–10206. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ghaleb AM, McConnell BB, Nandan MO, Katz
JP, Kaestner KH and Yang VW: Haploinsufficiency of Krüppel-like
factor 4 promotes adenomatous polyposis coli dependent intestinal
tumorigenesis. Cancer Res. 67:7147–7154. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lorentzen A, Vogel LK, Lewinsky RH, Saebø
M, Skjelbred CF, Godiksen S, Hoff G, Tveit KM, Lothe IM, Ikdahl T,
et al: Expression of NDRG2 is down-regulated in high-risk adenomas
and colorectal carcinoma. BMC Cancer. 7:1922007. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Takahashi K and Yamada M, Ohata H, Honda K
and Yamada M: Ndrg2 promotes neurite outgrowth of
NGF-differentiated PC12 cells. Neurosci Lett. 388:157–162. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Lee DC, Kang YK, Kim WH, Jang YJ, Kim DJ,
Park IY, Sohn BH, Sohn HA, Lee HG, Lim JS, et al: Functional and
clinical evidence for NDRG2 as a candidate suppressor of liver
cancer metastasis. Cancer Res. 68:4210–4220. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhao H, Zhang J, Lu J, He X, Chen C, Li X,
Gong L, Bao G, Fu Q, Chen S, et al: Reduced expression of N-Myc
downstream-regulated gene 2 in human thyroid cancer. BMC Cancer.
8:3032008. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Shi H, Li N, Li S, Chen C, Wang W, Xu C,
Zhang J, Jin H, Zhang H, Zhao H, et al: Expression of NDRG2 in
esophageal squamous cell carcinoma. Cancer Sci. 101:1292–1299.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Chu D, Zhang Z, Li Y, Wu L and Zhang J,
Wang W and Zhang J: Prediction of colorectal cancer relapse and
prognosis by tissue mRNA levels of NDRG2. Mol Cancer Ther.
10:47–56. 2011. View Article : Google Scholar : PubMed/NCBI
|
