|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bishop KS, Kao CH, Xu Y, Glucina MP,
Paterson RR and Ferguson LR: From 2000 years of Ganoderma lucidum
to recent developments in nutraceuticals. Phytochemistry.
114:56–65. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Akihisa T, Nakamura Y, Tagata M, Tokuda H,
Yasukawa K, Uchiyama E, Suzuki T and Kimura Y: Anti-inflammatory
and anti-tumor-promoting effects of triterpene acids and sterols
from the fungus Ganoderma lucidum. Chem Biodivers. 4:224–231. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ko HH, Hung CF, Wang JP and Lin CN:
Antiinflammatory triterpenoids and steroids from Ganoderma lucidum
and G. tsugae. Phytochemistry. 69:234–239. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hu H, Ahn NS, Yang X, Lee YS and Kang KS:
Ganoderma lucidum extract induces cell cycle arrest and apoptosis
in MCF-7 human breast cancer cell. Int J Cancer. 102:250–253. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wu G, Qian Z, Guo J, Hu D, Bao J, Xie J,
Xu W, Lu J, Chen X and Wang Y: Ganoderma lucidum extract induces G1
cell cycle arrest, and apoptosis in human breast cancer cells. Am J
Chin Med. 40:631–642. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Jang SH, Cho SW, Yoon HM, Jang KJ, Song CH
and Kim CH: Hepatoprotective evaluation of Ganoderma lucidum
pharmacopuncture: In vivo studies of ethanol-induced acute liver
injury. J Pharmacopuncture. 17:16–24. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Mowsumi FR, Rahman MM, Rahaman A, Selina
FA, Islam MJ and Bhuiyan MHS: Preventive effect of Ganoderma
lucidum on paraetamol-induced acute hepatotoxicity in rats.
Bangladesh J Sci Res. 5:573–578. 2013.
|
|
9
|
Lam FF, Ko IW, Ng ES, Tam LS, Leung PC and
Li EK: Analgesic and anti-arthritic effects of Lingzhi and San Miao
San supplementation in a rat model of arthritis induced by Freunds
complete adjuvant. J Ethnopharmacol. 120:44–50. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Koyama K, Imaizumi T, Akiba M, Kinoshita
K, Takahashi K, Suzuki A, Yano S, Horie S, Watanabe K and Naoi Y:
Antinociceptive components of Ganoderma lucidum. Planta Med.
63:224–227. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
el-Mekkawy S, Meselhy MR, Nakamura N,
Tezuka Y, Hattori M, Kakiuchi N, Shimotohno K, Kawahata T and Otake
T: Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma
lucidum. Phytochemistry. 49:1651–1657. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Wu GS, Guo JJ, Bao JL, Li XW, Chen XP, Lu
JJ and Wang YT: Anti-cancer properties of triterpenoids isolated
from Ganoderma lucidum - a review. Expert Opin Investig Drugs.
22:981–992. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Boh B, Berovic M, Zhang J and Zhi-Bin L:
Ganoderma lucidum and its pharmaceutically active compounds.
Biotechnol Annu Rev. 13:265–301. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Jang KJ, Son IS, Shin DY, Yoon HM and Choi
YH: Anti-invasive activity of ethanol extracts of Ganoderma lucidum
through tightening of tight junctions and inhibition of matrix
metalloproteinase activities in human gastric carcinoma cells. J
Acupunct Meridian Stud. 4:225–235. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Jang KJ, Han MH, Lee BH, Kim BW, Kim CH,
Yoon HM and Choi YH: Induction of apoptosis by ethanol extracts of
Ganoderma lucidum in human gastric carcinoma cells. J Acupunct
Meridian Stud. 3:24–31. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yuen JW, Gohel MD and Au DW:
Telomerase-associated apoptotic events by mushroom Ganoderma
lucidum on premalignant human urothelial cells. Nutr Cancer.
60:109–119. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhu HS, Yang XL, Wang LB, Zhao DX and Chen
L: Effects of extracts from sporoderm-broken spores of Ganoderma
lucidum on HeLa cells. Cell Biol Toxicol. 16:201–206. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hong KJ, Dunn DM, Shen CL and Pence BC:
Effects of Ganoderma lucidum on apoptotic and anti-inflammatory
function in HT-29 human colonic carcinoma cells. Phytother Res.
18:768–770. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lin SB, Li CH, Lee SS and Kan LS:
Triterpene-enriched extracts from Ganoderma lucidum inhibit growth
of hepatoma cells via suppressing protein kinase C, activating
mitogen-activated protein kinases and G2-phase cell cycle arrest.
Life Sci. 72:2381–2390. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Min BS, Nakamura N, Miyashiro H, Bae KW
and Hattori M: Triterpenes from the spores of Ganoderma lucidum and
their inhibitory activity against HIV-1 protease. Chem Pharm Bull
(Tokyo). 46:1607–1612. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Lu QY, Jin YS, Zhang Q, Zhang Z, Heber D,
Go VL, Li FP and Rao JY: Ganoderma lucidum extracts inhibit growth
and induce actin polymerization in bladder cancer cells in vitro.
Cancer Lett. 216:9–20. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wynne S and Djakiew D: NSAID inhibition of
prostate cancer cell migration is mediated by Nag-1 induction via
the p38 MAPK-p75(NTR) pathway. Mol Cancer Res. 8:1656–1664. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wang X, Baek SJ and Eling TE: The diverse
roles of nonsteroidal anti-inflammatory drug activated gene
(NAG-1/GDF15) in cancer. Biochem Pharmacol. 85:597–606. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Parekh HS, Liu G and Wei MQ: A new dawn
for the use of traditional Chinese medicine in cancer therapy. Mol
Cancer. 8:212009.https://doi.org/10.1201/b16611-11 View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hanahan D and Weinberg RA: The hallmarks
of cancer. Cell. 100:57–70. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lim S and Kaldis P: Cdks, cyclins and
CKIs: Roles beyond cell cycle regulation. Development.
140:3079–3093. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Alao JP: The regulation of cyclin D1
degradation: Roles in cancer development and the potential for
therapeutic invention. Mol Cancer. 6:242007. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Liu Y, Bi T, Wang Z, Wu G, Qian L, Gao Q
and Shen G: Oxymatrine synergistically enhances antitumor activity
of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
Apoptosis. 21:1398–1407. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Gong J, Ardelt B, Traganos F and
Darzynkiewicz Z: Unscheduled expression of cyclin B1 and cyclin E
in several leukemic and solid tumor cell lines. Cancer Res.
54:4285–4288. 1994.PubMed/NCBI
|
|
30
|
Cho HJ and Park JH: Kaempferol induces
cell cycle arrest in HT-29 human colon cancer cells. J Cancer Prev.
18:257–263. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lee DE, Lee KW, Jung SK, Lee EJ, Hwang JA,
Lim TG, Kim BY, Bode AM, Lee HJ and Dong Z:
6,7,4-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell
proliferation by targeting CDK1 and CDK2. Carcinogenesis.
32:629–635. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Graña X and Reddy EP: Cell cycle control
in mammalian cells: Role of cyclins, cyclin dependent kinases
(CDKs), growth suppressor genes and cyclin-dependent kinase
inhibitors (CKIs). Oncogene. 11:211–219. 1995.PubMed/NCBI
|
|
33
|
Ruan W, Wei Y and Popovich DG: Distinct
responses of cytotoxic Ganoderma lucidum triterpenoids in human
carcinoma cells. Phytother Res. 29:1744–1752. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang T, Xie ZP, Huang ZS, Li H, Wei AY, Di
JM, Xiao HJ, Zhang ZG, Cai LH, Tao X, et al: Total triterpenoids
from Ganoderma Lucidum suppresses prostate cancer cell growth by
inducing growth arrest and apoptosis. J Huazhong Univ Sci Technolog
Med Sci. 35:736–741. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Kobayashi T, Sawa H, Morikawa J, Zhang W
and Shiku H: Bax induction activates apoptotic cascade via
mitochondrial cytochrome c release and Bax overexpression enhances
apoptosis induced by chemotherapeutic agents in DLD-1 colon cancer
cells. Jpn J Cancer Res. 91:1264–1268. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Paul-Samojedny MI, Kokocińska D, Samojedny
A, Mazurek U, Partyka R, Lorenz Z and Wilczok T: Expression of cell
survival/death genes: Bcl-2 and Bax at the rate of colon cancer
prognosis. Biochim Biophys Acta. 25-29:2005.
|
|
37
|
Shim M and Eling TE: Vitamin E succinate
induces NAG-1 expression in a p38 kinase-dependent mechanism. Mol
Cancer Ther. 7:961–971. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Chen Y, Lv J, Li K, Xu J, Li M, Zhang W
and Pang X: Sporoderm-broken spores of Ganoderma lucidum inhibit
the growth of lung cancer: Involvement of the Akt/mTOR signaling
pathway. Nutr Cancer. 68:1151–1160. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Thyagarajan A, Jedinak A, Nguyen H, Terry
C, Baldridge LA, Jiang J and Sliva D: Triterpenes from Ganoderma
Lucidum induce autophagy in colon cancer through the inhibition of
p38 mitogen-activated kinase (p38 MAPK). Nutr Cancer. 62:630–640.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Alves C Castro, Rosivatz E, Schott C,
Hollweck R, Becker I, Sarbia M, Carneiro F and Becker KF: Slug is
overexpressed in gastric carcinomas and may act synergistically
with SIP1 and Snail in the down-regulation of E-cadherin. J Pathol.
211:507–515. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Shin DH, Dier U, Melendez JA and Hempel N:
Regulation of MMP-1 expression in response to hypoxia is dependent
on the intracellular redox status of metastatic bladder cancer
cells. Biochim Biophys Acta. 1852:2593–2602. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Martínez-Montemayor MM, Acevedo RR,
Otero-Franqui E, Cubano LA and Dharmawardhane SF: Ganoderma lucidum
(Reishi) inhibits cancer cell growth and expression of key
molecules in inflammatory breast cancer. Nutr Cancer. 63:1085–1094.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Liu LY, Chen H, Liu C, Wang HQ, Kang J, Li
Y and Chen RY: Triterpenoids of Ganoderma theaecolum and their
hepatoprotective activities. Fitoterapia. 98:254–259. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Shi Y, Sun J, He H, Guo H and Zhang S:
Hepatoprotective effects of Ganoderma lucidum peptides against
D-galactosamine-induced liver injury in mice. J Ethnopharmacol.
117:415–419. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Kwok Y, Ng KF, Li CC, Lam CC and Man RY: A
prospective, randomized, double-blind, placebo-controlled study of
the platelet and global hemostatic effects of Ganoderma lucidum
(Ling-Zhi) in healthy volunteers. Anesth Analg. 101:423–426, table
of contents. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Noguchi M, Kakuma T, Tomiyasu K, Yamada A,
Itoh K, Konishi F, Kumamoto S, Shimizu K, Kondo R and Matsuoka K:
Randomized clinical trial of an ethanol extract of Ganoderma
lucidum in men with lower urinary tract symptoms. Asian J Androl.
10:777–785. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Wachtel-Galor S, Szeto YT, Tomlinson B and
Benzie IF: Ganoderma lucidum (‘Lingzhi’); acute and short-term
biomarker response to supplementation. Int J Food Sci Nutr.
55:75–83. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Zhuang SR, Chen SL, Tsai JH, Huang CC, Wu
TC, Liu WS, Tseng HC, Lee HS, Huang MC, Shane GT, et al: Effect of
citronellol and the Chinese medical herb complex on cellular
immunity of cancer patients receiving chemotherapy/radiotherapy.
Phytother Res. 23:785–790. 2009. View Article : Google Scholar : PubMed/NCBI
|
