|
1
|
Zhang X, Lin Y and Gillies RJ: Tumor pH
and its measurement. J Nucl Med. 51:1167–1170. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hernandez A, Serrano-Bueno G,
Perez-Castineira JR and Serrano A: Intracellular proton pumps as
targets in chemotherapy: V-ATPases and cancer. Curr Pharm Des.
18:1383–1394. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Shen W, Zou X, Chen M, Liu P, Shen Y,
Huang S, Guo H and Zhang L: Effects of diphyllin as a novel
V-ATPase inhibitor on gastric adenocarcinoma. Eur J Pharmacol.
667:330–338. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2013. CA Cancer J Clin. 63:11–30. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Gomes FG, Nedel F, Alves AM, Nör JE and
Tarquinio SB: Tumor angiogenesis and lymphangiogenesis:
Tumor/endothelial crosstalk and cellular/microenvironmental
signaling mechanisms. Life Sci. 92:101–107. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Liu P, Chen W, Zhu H, Liu B, Song S, Shen
W, Wang F, Tucker S, Zhong B and Wang D: Expression of VEGF-C
correlates with a poor prognosis based on analysis of prognostic
factors in 73 patients with esophageal squamous cell carcinomas.
Jpn J Clin Oncol. 39:644–650. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Liu P, Zhou J, Zhu H, Xie L, Wang F, Liu
B, Shen W, Ye W, Xiang B, Zhu X, et al: VEGF-C promotes the
development of esophageal cancer via regulating CNTN-1 expression.
Cytokine. 55:8–17. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Shin J, Lee HJ, Jung DB, Jung JH, Lee HJ,
Lee EO, Lee SG, Shim BS, Choi SH, Ko SG, et al: Suppression of
STAT3 and HIF-1 alpha mediates anti-angiogenic activity of
betulinic acid in hypoxic PC-3 prostate cancer cells. PLoS One.
6:e214922011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Elias AP and Dias S: Microenvironment
changes (in pH) affect VEGF alternative splicing. Cancer
Microenviron. 1:131–139. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kraut JA and Madias NE: Metabolic
acidosis: Pathophysiology, diagnosis and management. Nat Rev
Nephrol. 6:274–285. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Le Tourneau C, Faivre S, Serova M and
Raymond E: mTORC1 inhibitors: Is temsirolimus in renal cancer
telling us how they really work? Br J Cancer. 99:1197–1203. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Liu P, Chen H, Han L, Zhou X and Shen W:
Expression and role of V1A subunit of V-ATPase in gastric cancer
cells. Int J Clin Oncol. 20:725–735. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Das S, Ladell DS, Podgrabinska S,
Ponomarev V, Nagi C, Fallon JT and Skobe M: Vascular endothelial
growth factor-C induces lymphangitic carcinomatosis, an extremely
aggressive form of lung metastases. Cancer Res. 70:1814–1824. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wang Y, Xia C, Zhang W and Zhao Y:
Synthesis and biological evaluation of novel lignan glycosides as
anticancer agents. Chem Biol Drug Des. 88:562–567. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Efeyan A, Zoncu R, Sabatini DM, Wang S and
Sancak Y: Amino acids and mTORC1: From lysosomes to disease. Trends
Mol Med. 18:524–533. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Balgi AD, Diering GH, Donohue E, Lam KK,
Fonseca BD, Zimmerman C, Numata M and Roberge M: Regulation of
mTORC1 signaling by pH. PLoS One. 6:e215492011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Naito T, Kuma A and Mizushima N:
Differential contribution of insulin and amino acids to the
mTORC1-autophagy pathway in the liver and muscle. J Biol Chem.
288:21074–21081. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Sørensen MG, Henriksen K, Neutzsky-Wulff
AV, Dziegiel MH and Karsdal MA: Diphyllin, a novel and naturally
potent V-ATPase inhibitor, abrogates acidification of the
osteoclastic resorption lacunae and bone resorption. J Bone Miner
Res. 22:1640–1648. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhao Y, Ni C, Zhang Y and Zhu L: Synthesis
and bioevaluation of diphyllin glycosides as novel anticancer
agents. Arch Pharm. 345:622–628. 2012. View Article : Google Scholar
|
|
20
|
Zoncu R, Bar-Peled L, Efeyan A, Wang S,
Sancak Y and Sabatini DM: mTORC1 senses lysosomal amino acids
through an inside-out mechanism that requires the vacuolar
H+-ATPase. Science. 334:678–683. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhou M, Morgner N, Barrera NP, Politis A,
Isaacson SC, Matak-Vinković D, Murata T, Bernal RA, Stock D and
Robinson CV: Mass spectrometry of intact V-type ATPases reveals
bound lipids and the effects of nucleotide binding. Science.
334:380–385. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Shen W, Zou X, Chen M, Shen Y, Huang S,
Guo H, Zhang L and Liu P: Effect of pantoprazole on human gastric
adenocarcinoma SGC7901 cells through regulation of phospho-LRP6
expression in Wnt/β-catenin signaling. Oncol Rep. 30:851–855. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhao Y, Lu Y, Ma J and Zhu L: Synthesis
and evaluation of cleistanthin A derivatives as potent vacuolar
H+-ATPase inhibitors. Chem Biol Drug Des. 86:691–696.
2015. View Article : Google Scholar : PubMed/NCBI
|
