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Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis

  • Authors:
    • Huan Yang
    • Shuang Wang
    • Yu-Jun Kang
    • Chuan Wang
    • Yongzhu Xu
    • Yi Zhang
    • Zheng Jiang
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, P.R. China, Department of Gastroenterology, Chongqing People's Hospital, Chongqing 400016, P.R. China, Chongqing Health Service Center, Chongqing 400000, P.R. China, Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning of Chongqing Science and Technology Research Institute, Chongqing 400000, P.R. China
    Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 261-271
    |
    Published online on: May 2, 2018
       https://doi.org/10.3892/or.2018.6412
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Abstract

Colon cancer is the main cause of cancer mortality worldwide. Its poor prognosis is mainly ascribed to high recurrence rates. Identifying novel prognostic biomarkers and therapeutic key points for management is crucial and important. Long non-coding RNAs (lncRNAs) are a class of RNAs, which have various roles in carcinogenicity and molecular mechanisms. The lncRNA small nucleolar RNA host gene 1 (SNHG1) contributes to the promotion of tumor development, however, the connections between SNHG1 and colon cancer are still unclear. The aim of the present study was to investigate the clinical significance, the biological functions, and the potential mechanism of SNHG1 in colon cancer. In the present study, we referred to the Oncomine database and used RT-qPCR to determine that SNHG1 expression was significantly higher both in colon cancer tissues and cancerous cell lines than in normal samples. Cell functional experiments were performed after knockdown of SNHG1, including Cell Counting Kit-8 assay, colony formation assay, Transwell® assay, and flow cytometric analyses of cell apoptosis, which suggested that SNHG1 stimulated colon cancer cell proliferation, promoted cell invasion and migration, and inhibited apoptosis. Immunohistochemical staining and western blotting experiments revealed that in colon cancer cells with SNHG1 knockdown, β-catenin, c-Myc and cyclin D1 protein levels were decreased, while E-cadherin was increased, which suggested that SNHG1 promoted colon cancer cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway. Our results indicated that SNHG1 and its interrelated components may be future therapeutic targets of carcinoma of the colon.
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1 

Negm OH, Hamed MR, Schoen RE, Whelan RL, Steele RJ, Scholefield J, Dilnot EM, Kumara Shantha HM, Robertson JF and Sewell HF: Human blood autoantibodies in the detection of colorectal cancer. PLoS One. 11:e01569712016. View Article : Google Scholar : PubMed/NCBI

2 

Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, Rosso S, Coebergh JW, Comber H, Forman D and Bray F: Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012. Eur J Cancer. 49:1374–1403. 2013. View Article : Google Scholar : PubMed/NCBI

3 

Fatica A and Bozzoni I: Long non-coding RNAs: New players in cell differentiation and development. Nat Rev Genet. 15:7–21. 2014. View Article : Google Scholar : PubMed/NCBI

4 

Yuan JH, Yang F, Wang F, Ma JZ, Guo YJ, Tao QF, Liu F, Pan W, Wang TT, Zhou CC, et al: A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma. Cancer Cell. 25:666–681. 2014. View Article : Google Scholar : PubMed/NCBI

5 

Peng W and Fan H: Long non-coding RNA PANDAR correlates with poor prognosis and promotes tumorigenesis in hepatocellular carcinoma. Biomed Pharmacother. 72:113–118. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Deng J, Liang Y, Liu C, He S and Wang S: The up-regulation of long non-coding RNA AFAP1-AS1 is associated with the poor prognosis of NSCLC patients. Biomed Pharmacother. 75:8–11. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Li L, Zhang L, Zhang Y and Zhou F: Increased expression of LncRNA BANCR is associated with clinical progression and poor prognosis in gastric cancer. Biomed Pharmacother. 72:109–112. 2015. View Article : Google Scholar : PubMed/NCBI

8 

Chen J, Fu Z, Ji C, Gu P, Xu P, Yu N, Kan Y, Wu X, Shen R and Shen Y: Systematic gene microarray analysis of the lncRNA expression profiles in human uterine cervix carcinoma. Biomed Pharmacother. 72:83–90. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Yang Q, Xu E, Dai J, Liu B, Han Z, Wu J, Zhang S, Peng B, Zhang Y and Jiang Y: A novel long noncoding RNA AK001796 acts as an oncogene and is involved in cell growth inhibition by resveratrol in lung cancer. Toxicol Appl Pharmacol. 285:79–88. 2015. View Article : Google Scholar : PubMed/NCBI

10 

Cui Y, Zhang F, Zhu C, Geng L, Tian T and Liu H: Upregulated lncRNA SNHG1 contributes to progression of non-small cell lung cancer through inhibition of miR-101-3p and activation of Wnt/β-catenin signaling pathway. Oncotarget. 8:17785–17794. 2017.PubMed/NCBI

11 

Yan Y, Fan Q, Wang L, Zhou Y, Li J and Zhou K: LncRNA Snhg1, a non-degradable sponge for miR-338, promotes expression of proto-oncogene CST3 in primary esophageal cancer cells. Oncotarget. 8:35750–35760. 2017.PubMed/NCBI

12 

Li J, Zhang Z, Xiong L, Guo C, Jiang T, Zeng L, Li G and Wang J: SNHG1 lncRNA negatively regulates miR-199a-3p to enhance CDK7 expression and promote cell proliferation in prostate cancer. Biochem Biophys Res Commun. 487:146–152. 2017. View Article : Google Scholar : PubMed/NCBI

13 

Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A and Chinnaiyan AM: ONCOMINE: A cancer microarray database and integrated data-mining platform. Neoplasia. 6:1–6. 2004. View Article : Google Scholar : PubMed/NCBI

14 

Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varambally R, Yu J, Briggs BB, Barrette TR, Anstet MJ, Kincead-Beal C, Kulkarni P, et al: Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia. 9:166–180. 2007. View Article : Google Scholar : PubMed/NCBI

15 

Jalving M, Heijink DM, Koornstra JJ, Boersma-van Ek W, Zwart N, Wesseling J, Sluiter WJ, de Vries EG, Kleibeuker JH and de Jong S: Regulation of TRAIL receptor expression by β-catenin in colorectal tumours. Carcinogenesis. 35:1092–1099. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Rashed HE, Hussein S, Mosaad H, Abdelwahab MM, Abdelhamid MI, Mohamed SY, Mohamed AM and Fayed A: Prognostic significance of the genetic and the immunohistochemical expression of epithelial-mesenchymal-related markers in colon cancer. Cancer Biomark. 20:107–122. 2017. View Article : Google Scholar : PubMed/NCBI

17 

Ji L, Wei Y, Jiang T and Wang S: Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their relationships to clinicopathologic features and survival. Int J Clin Exp Pathol. 7:1124–1131. 2014.PubMed/NCBI

18 

Senol S, Ceyran AB, Kösemetin D, Gobanoglu B, Aydin D, Duran EA and Leblebici M: Immunohistochemical profile of tumor pathways and prognostic significance in colon adenocarcinomas. J Environ Pathol Toxicol Oncol. 36:29–41. 2017. View Article : Google Scholar : PubMed/NCBI

19 

Weijun C, Hailu W, Yushu Z and Zhenqiu C: Study on expression of long non-coding RNA in colon carcinoma. Linchuang Zhongliuxue Zazhi. 18:882–886. 2013.

20 

Xu X, Chen R, Li Z, Huang N, Wu X, Li S, Li Y and Wu S: MicroRNA-490-3p inhibits colorectal cancer metastasis by targeting TGFβR1. BMC Cancer. 15:10232015. View Article : Google Scholar : PubMed/NCBI

21 

Agüero F, Murta-Nascimento C, Gallén M, Andreu-García M, Pera M, Hernández C, Burón A and Macià F: Colorectal cancer survival: Results from a hospital-based cancer registry. Rev Esp Enferm Dig. 104:572–577. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Yan X, Hu Z, Feng Y, Hu X, Yuan J, Zhao SD, Zhang Y, Yang L, Shan W, He Q, et al: Comprehensive genomic characterization of long non-coding RNAs across human cancers. Cancer Cell. 28:529–540. 2015. View Article : Google Scholar : PubMed/NCBI

23 

Hu X, Feng Y, Zhang D, Zhao SD, Hu Z, Greshock J, Zhang Y, Yang L, Zhong X, Wang LP, et al: A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. Cancer Cell. 26:344–357. 2014. View Article : Google Scholar : PubMed/NCBI

24 

Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, et al: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. 528:517–522. 2015. View Article : Google Scholar : PubMed/NCBI

25 

Zhang M, Wang W, Li T, Yu X, Zhu Y, Ding F, Li D and Yang T: Long noncoding RNA SNHG1 predicts a poor prognosis and promotes hepatocellular carcinoma tumorigenesis. Biomed Pharmacother. 80:73–79. 2016. View Article : Google Scholar : PubMed/NCBI

26 

You J, Fang N, Gu J, Zhang Y, Li X, Zu L and Zhou Q: Non-coding RNA small nucleolar RNA host gene 1 promote cell proliferation in nonsmall cell lung cancer. Indian J Cancer. 7:99–102. 2014. View Article : Google Scholar

27 

Chaudhry MA: Small nucleolar RNA host genes and long non-coding RNA responses in directly irradiated and bystander cells. Cancer Biother Radiopharm. 29:135–141. 2014. View Article : Google Scholar : PubMed/NCBI

28 

Sahu D, Hsu CL, Lin CC, Yang TW, Hsu WM, Ho SY, Juan HF and Huang HC: Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma. Oncotarget. 7:58022–58037. 2016. View Article : Google Scholar : PubMed/NCBI

29 

Rosenbluh J, Wang X and Hahn WC: Genomic insights into WNT/β-catenin signaling. Trends Pharmacol Sci. 35:103–109. 2014. View Article : Google Scholar : PubMed/NCBI

30 

Cui J, Zhou X, Liu Y, Tang Z and Romeih M: Wnt signaling in hepatocellular carcinoma: Analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes. J Gastroenterol Hepatol. 18:280–287. 2003. View Article : Google Scholar : PubMed/NCBI

31 

Prasetyanti PR, Zimberlin CD, Bots M, Vermeulen L, Melo FS and Medema JP: Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon. Mol Cancer. 12:1262013. View Article : Google Scholar : PubMed/NCBI

32 

Greco A, De Virgilio A, Rizzo MI, Pandolfi F, Rosati D and de Vincentiis M: The prognostic role of E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma. Laryngoscope. 126:E148–E155. 2016. View Article : Google Scholar : PubMed/NCBI

33 

Guarino M, Rubino B and Ballabio G: The role of epithelial-mesenchymal transition in cancer pathology. Pathology. 39:305–318. 2007. View Article : Google Scholar : PubMed/NCBI

34 

Stoyianni A, Goussia A, Pentheroudakis G, Siozopoulou V, Ioachim E, Krikelis D, Golfinopoulos V, Cervantes A, Bobos M, Fotsis T, et al: Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: Incidence, correlations and prognostic utility. Anticancer Res. 32:1273–1281. 2012.PubMed/NCBI

35 

MacDonald BT, Tamai K and He X: Wnt/β-catenin signaling: Components, mechanisms, and diseases. Dev Cell. 17:9–26. 2009. View Article : Google Scholar : PubMed/NCBI

36 

Vlad A, Röhrs S, Klein-Hitpass L and Müller O: The first five years of the Wnt targetome. Cell Signal. 20:795–802. 2008. View Article : Google Scholar : PubMed/NCBI

37 

Prensner JR, Chen W, Han S, Iyer MK, Cao Q, Kothari V, Evans JR, Knudsen KE, Paulsen MT, Ljungman M, et al: The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc. Neoplasia. 16:900–908. 2014. View Article : Google Scholar : PubMed/NCBI

38 

Yamamoto K, Lee BJ, Li C, Dubois RL, Hobeika E, Bhagat G and Zha S: Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice. Leukemia. 29:1414–1424. 2015. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Yang H, Wang S, Kang Y, Wang C, Xu Y, Zhang Y and Jiang Z: Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis. Oncol Rep 40: 261-271, 2018.
APA
Yang, H., Wang, S., Kang, Y., Wang, C., Xu, Y., Zhang, Y., & Jiang, Z. (2018). Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis. Oncology Reports, 40, 261-271. https://doi.org/10.3892/or.2018.6412
MLA
Yang, H., Wang, S., Kang, Y., Wang, C., Xu, Y., Zhang, Y., Jiang, Z."Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis". Oncology Reports 40.1 (2018): 261-271.
Chicago
Yang, H., Wang, S., Kang, Y., Wang, C., Xu, Y., Zhang, Y., Jiang, Z."Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis". Oncology Reports 40, no. 1 (2018): 261-271. https://doi.org/10.3892/or.2018.6412
Copy and paste a formatted citation
x
Spandidos Publications style
Yang H, Wang S, Kang Y, Wang C, Xu Y, Zhang Y and Jiang Z: Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis. Oncol Rep 40: 261-271, 2018.
APA
Yang, H., Wang, S., Kang, Y., Wang, C., Xu, Y., Zhang, Y., & Jiang, Z. (2018). Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis. Oncology Reports, 40, 261-271. https://doi.org/10.3892/or.2018.6412
MLA
Yang, H., Wang, S., Kang, Y., Wang, C., Xu, Y., Zhang, Y., Jiang, Z."Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis". Oncology Reports 40.1 (2018): 261-271.
Chicago
Yang, H., Wang, S., Kang, Y., Wang, C., Xu, Y., Zhang, Y., Jiang, Z."Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis". Oncology Reports 40, no. 1 (2018): 261-271. https://doi.org/10.3892/or.2018.6412
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