Journal Articles
Review
BIIB021, an Hsp90 inhibitor: A promising therapeutic strategy for blood malignancies (Review)
Wei He, Huixian Hu
Pages: 3-15 Published online on: 08 May 2018
Review
Multifaceted regulation and functions of YAP/TAZ in tumors (Review)
Huirong Liu, Suya Du, Tiantian Lei, Hailian Wang, Xia He, Rongsheng Tong, Yi Wang
Pages: 16-28 Published online on: 08 May 2018
Article
EGF upregulates RFPL3 and hTERT via the MEK signaling pathway in non‑small cell lung cancer cells
Chuan Lin, Yu Qin, Hua Zhang, Ming‑Yang Gao, Yan‑Fu Wang
Pages: 29-38 Published online on: 08 May 2018
Article
MEG3/miR‑21 axis affects cell mobility by suppressing epithelial‑mesenchymal transition in gastric cancer
Gang Xu, Lei Meng, Dawei Yuan, Kang Li, Yong Zhang, Chengxue Dang, Kun Zhu
Pages: 39-48 Published online on: 08 May 2018
Article
Methylation of the claudin‑3 promoter predicts the prognosis of advanced gastric adenocarcinoma
Zhenzhen Zhang, Weixing Yu, Shuqin Chen, Yupeng Chen, Linying Chen, Sheng Zhang
Pages: 49-60 Published online on: 02 May 2018
Article
MicroRNA-125b inhibits cell proliferation and induces cell apoptosis in esophageal squamous cell carcinoma by targeting BMF
Yan-Xin Fan, Xiu-Hua Bian, Pu-Dong Qian, Zhen-Zhang Chen, Jing Wen, Yan-Hong Luo, Peng-Wei Yan, Qian Zhang
Pages: 61-72 Published online on: 02 May 2018
Article
Purple sweet potato anthocyanin exerts antitumor effect in bladder cancer
Wei-Lin Li, Hong-Yuan Yu, Xian-Jun Zhang, Mang Ke, Tao Hong
Pages: 73-82 Published online on: 08 May 2018
Article
Oncogenic role of miR‑183‑5p in lung adenocarcinoma: A comprehensive study of qPCR, in vitro experiments and bioinformatic analysis
Rong‑Quan He, Li Gao, Jie Ma, Zu‑Yun Li, Xiao‑Hua Hu, Gang Chen
Pages: 83-100 Published online on: 09 May 2018
Article
Mina53 nuclear localization is an important indicator of prognosis in patients with colorectal cancer after adjuvant chemotherapy
Shinya Fujino, Tetsushi Kinugasa, Tomoya Sudo, Tomoaki Mizobe, Takefumi Yoshida, Naohiro Yoshida, Takafumi Ohchi, Kensuke Tajiri, Kotaro Yuge, Sachiko Nagasu, Mitsuhiro Katagiri, Yoshito Akagi
Pages: 101-110 Published online on: 30 April 2018
Article
Integrated bioinformatics analysis reveals that the expression of cathepsin S is associated with lymph node metastasis and poor prognosis in papillary thyroid cancer
Juan Tan, Xiaoxiao Qian, Bin Song, Xiumin An, Tingting Cai, Zhihua Zuo, Dafa Ding, Yibing Lu, Hong Li
Pages: 111-122 Published online on: 08 May 2018
Article
Potential role of cyclin F mRNA expression in the survival of skin melanoma patients: Comprehensive analysis of the pathways altered due to cyclin F upregulation
Maciej Gagat, Adrian Krajewski, Dariusz Grzanka, Alina Grzanka
Pages: 123-144 Published online on: 16 May 2018
Article
Use of CA15‑3 for screening breast cancer: An antibody‑lectin sandwich assay for detecting glycosylation of CA15‑3 in sera
Jae Woong Choi, Byung‑In Moon, Jun Woo Lee, Hyoung Jin Kim, Yingji Jin, Hong‑Jin Kim
Pages: 145-154 Published online on: 10 May 2018
Article
Specific inhibitor of Notch‑3 enhances the sensitivity of NSCLC cells to gemcitabine
Bi‑Dan Hu, Jia Guo, Yuan‑Zi Ye, Ting Du, Chun‑Song Cheng, Qian Jiang, Ruo‑Nan Liu, Yan‑Bei Zhang
Pages: 155-164 Published online on: 16 May 2018
Article
Comparison of the synergistic anticancer activity of AlPcS4 photodynamic therapy in combination with different low‑dose chemotherapeutic agents on gastric cancer cells
Jing Xin, Senhao Wang, Luwei Zhang, Bo Xin, Yulu He, Jing Wang, Sijia Wang, Lijian Shen, Zhenxi Zhang, Cuiping Yao
Pages: 165-178 Published online on: 16 May 2018
Article
Knockdown of KPNA2 inhibits autophagy in oral squamous cell carcinoma cell lines by blocking p53 nuclear translocation
Feng Lin, Li Gao, Zhenyu Su, Xiaofang Cao, Yuanbo Zhan, Ying Li, Bin Zhang
Pages: 179-194 Published online on: 17 May 2018
Article
KIF20A expression as a prognostic indicator and its possible involvement in the proliferation of ovarian clear‑cell carcinoma cells
Yosuke Kawai, Kiyosumi Shibata, Jun Sakata, Shiro Suzuki, Fumi Utsumi, Kaoru Niimi, Ryuichiro Sekiya, Takeshi Senga, Fumitaka Kikkawa, Hiroaki Kajiyama
Pages: 195-205 Published online on: 25 April 2018
Article
TRIM58/cg26157385 methylation is associated with eight prognostic genes in lung squamous cell carcinoma
Weimin Zhang, Qichen Cui, Weifeng Qu, Xiaoyun Ding, Donglin Jiang, Hongcheng Liu
Pages: 206-216 Published online on: 08 May 2018
Article
βKlotho inhibits androgen/androgen receptor‑associated epithelial‑mesenchymal transition in prostate cancer through inactivation of ERK1/2 signaling
Zhao Liu, Hui Zhang, Sentai Ding, Shasha Qi, Shuai Liu, Dingqi Sun, Wei Dong, Lei Yin, Mingjiang Li, Xingbo Zhao, Jiaju Lu
Pages: 217-225 Published online on: 25 April 2018
Article
Microarray‑based bioinformatics analysis of the prospective target gene network of key miRNAs influenced by long non‑coding RNA PVT1 in HCC
Yu Zhang, Wei‑Jia Mo, Xiao Wang, Tong‑Tong Zhang, Yuan Qin, Han‑Lin Wang, Gang Chen, Dan‑Ming Wei, Yi‑Wu Dang
Pages: 226-240 Published online on: 02 May 2018
Article
Insufficient radiofrequency ablation promotes hepatocellular carcinoma cell progression via autophagy and the CD133 feedback loop
Xiaofei Wang, Qingsong Deng, Kai Feng, Shihan Chen, Jiayun Jiang, Feng Xia, Kuansheng Ma, Ping Bie
Pages: 241-251 Published online on: 26 April 2018
Article
MicroRNA-150 inhibits the proliferation and metastasis potential of colorectal cancer cells by targeting iASPP
Chen Li, Xiaohui Du, Shaoyou Xia, Lin Chen
Pages: 252-260 Published online on: 30 April 2018
Article
Long non-coding RNA SNHG1 predicts a poor prognosis and promotes colon cancer tumorigenesis
Huan Yang, Shuang Wang, Yu-Jun Kang, Chuan Wang, Yongzhu Xu, Yi Zhang, Zheng Jiang
Pages: 261-271 Published online on: 02 May 2018
Article
miR-142-5p regulates CD4+ T cells in human non-small cell lung cancer through PD-L1 expression via the PTEN pathway
Jun Wan, Xiean Ling, Bin Peng, Guanggui Ding
Pages: 272-282 Published online on: 16 May 2018
Article
Downregulation of RPN2 induces apoptosis and inhibits migration and invasion in colon carcinoma
Chongyao Bi, Baofei Jiang
Pages: 283-293 Published online on: 10 May 2018
Article
Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells
Kuo-Hung Huang, I-Cheng Sung, Wen-Liang Fang, Chin-Wen Chi, Tien-Shun Yeh, Hsin-Chen Lee, Pen-Hui Yin, Anna Fen-Yau Li, Chew-Wun Wu, Yi-Ming Shyr, Muh-Hwa Yang
Pages: 294-302 Published online on: 16 May 2018
Article
Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells
Daisuke Uchida, Nobuyuki Kuribayashi, Makoto Kinouchi, Yuta Sawatani, Michiko Shimura, Toshimitsu Mori, Tomonori Hasegawa, Youji Miyamoto, Hitoshi Kawamata
Pages: 303-308 Published online on: 25 April 2018
Article
Somatic copy number alterations have prognostic impact in patients with ovarian clear cell carcinoma
Asuka Morikawa, Tomoatsu Hayashi, Mana Kobayashi, Yuki Kato, Katsuhiko Shirahige, Takehiko Itoh, Mitsuyoshi Urashima, Aikou Okamoto, Tetsu Akiyama
Pages: 309-318 Published online on: 08 May 2018
Article
Exosome‑encapsulated microRNA‑23b as a minimally invasive liquid biomarker for the prediction of recurrence and prognosis of gastric cancer patients in each tumor stage
Yoshimasa Kumata, Hisae Iinuma, Yusuke Suzuki, Daisuke Tsukahara, Hironori Midorikawa, Yuichi Igarashi, Naruyoshi Soeda, Takashi Kiyokawa, Masahiro Horikawa, Ryoji Fukushima
Pages: 319-330 Published online on: 08 May 2018
Article
PD-L1 mRNA expression in EGFR-mutant lung adenocarcinoma
Kazutoshi Isobe, Atsushi Kakimoto, Tetuo Mikami, Kyohei Kaburaki, Hiroshi Kobayashi, Takahiro Yoshizawa, Yuta Nakano, Takashi Makino, Hajime Otsuka, Go Sano, Keishi Sugino, Susumu Sakamoto, Yujiro Takai, Naobumi Tochigi, Akira Iyoda, Sakae Homma
Pages: 331-338 Published online on: 16 May 2018
Article
Enhanced production of reactive oxygen species in HeLa cells under concurrent low‑dose carboplatin and Photofrin® photodynamic therapy
Younshick Choi, Ji‑Eun Chang, Sanghoon Jheon, Sei‑Jun Han, Jong‑Ki Kim
Pages: 339-345 Published online on: 03 May 2018
Article
HDAC inhibitors, trichostatin A and valproic acid, increase E‑cadherin and vimentin expression but inhibit migration and invasion of cholangiocarcinoma cells
Joon Ho Wang, Eun Jeoung Lee, Meiying Ji, Seon Mee Park
Pages: 346-354 Published online on: 16 May 2018
Article
Suppression of RRM2 inhibits cell proliferation, causes cell cycle arrest and promotes the apoptosis of human neuroblastoma cells and in human neuroblastoma RRM2 is suppressed following chemotherapy
Junfeng Li, Jinglin Pang, Yongdong Liu, Jing Zhang, Chuanguang Zhang, Gang Shen, Lili Song
Pages: 355-360 Published online on: 08 May 2018
Article
Elemental diet inhibits pro‑inflammatory cytokine production in keratinocytes through the suppression of NF‑κB activation
Koji Harada, Tarannum Ferdous, Yoichi Mizukami, Katsuaki Mishima
Pages: 361-368 Published online on: 16 May 2018
Article
Inhibition of SOX4 induces melanoma cell apoptosis via downregulation of NF-κB p65 signaling
Qiong Cheng, Juan Du, Lin Xie, Xiao Liu, Zheng Li, Fuguo Zuo, Jinfeng Wu, Jinhua Xu
Pages: 369-376 Published online on: 16 May 2018
Article
EBV‑LMP1 is involved in vasculogenic mimicry formation via VEGFA/VEGFR1 signaling in nasopharyngeal carcinoma
San Xu, Ju Bai, Zhou Zhuan, Bo Li, Zhibao Zhang, Xia Wu, Xiangjian Luo, Lifang Yang
Pages: 377-384 Published online on: 03 May 2018
Article
Inhibition of endoplasmic reticulum stress-induced autophagy sensitizes melanoma cells to temozolomide treatment
Oxana Ryabaya, Anastasia Prokofieva, Dmitry Khochenkov, Ivan Abramov, Alexander Zasedatelev, Evgenia Stepanova
Pages: 385-394 Published online on: 09 May 2018
Article
Microarray analysis of circular RNA expression profiles associated with gemcitabine resistance in pancreatic cancer cells
Chao Xu, Yue Yu, Fei Ding
Pages: 395-404 Published online on: 17 May 2018
Article
CHAF1B knockdown blocks migration in a hepatocellular carcinoma model
Xiaodong Peng, Huiying Fu, Jianjun Yin, Qingmei Zhao
Pages: 405-413 Published online on: 16 May 2018
Article
Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells
Masaru Terasaki, Masatoshi Mima, Satoki Kudoh, Tetsuya Endo, Hayato Maeda, Junichi Hamada, Kazumi Osada, Kazuo Miyashita, Michihiro Mutoh
Pages: 414-424 Published online on: 24 April 2018
Article
LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells Corrigendum in /10.3892/or.2018.6495
Ye Wei, Tiantian Han, Ranran Wang, Jing Wei, Ke Peng, Qiong Lin, Genbao Shao
Pages: 425-433 Published online on: 10 May 2018
Article
Transcutaneous carbon dioxide enhances the antitumor effect of radiotherapy on oral squamous cell carcinoma
Eiji Iwata, Takumi Hasegawa, Takeshi Ueha, Daisuke Takeda, Izumi Saito, Teruya Kawamoto, Toshihiro Akisue, Yoshitada Sakai, Ryohei Sasaki, Ryosuke Kuroda, Takahide Komori
Pages: 434-442 Published online on: 16 May 2018
Article
Cross-link regulation of precursor N-cadherin and FGFR1 by GDNF increases U251MG cell viability
Chuan-Xi Tang, Yan-Xia Gu, Xin-Feng Liu, Shu-Yan Tong, Abiola A. Ayanlaja, Yue Gao, Guang-Quan Ji, Ye Xiong, Lin-Yan Huang, Dian-Shuai Gao
Pages: 443-453 Published online on: 30 April 2018
Article
Downregulation of occludin affects the proliferation, apoptosis and metastatic properties of human lung carcinoma
Meifang Wang, Yuquan Liu, Xin Qian, Na Wei, Yijun Tang, Jiong Yang
Pages: 454-462 Published online on: 02 May 2018
Article
Tumour cell dormancy as a contributor to the reduced survival of GBM patients who received standard therapy
Luqing Tong, Li Yi, Peidong Liu, Iruni Roshanie Abeysekera, Long Hai, Tao Li, Zhennan Tao, Haiwen Ma, Yang Xie, Yubao Huang, Shengping Yu, Jiabo Li, Feng Yuan, Xuejun Yang
Pages: 463-471 Published online on: 08 May 2018
Article
ClC-3 chloride channel protein induces G1 arrest in hepatocellular carcinoma Hep3B cells
Rui Wang, Bijun Kang, Rendong Hu, Youwai Huang, Zixi Qin, Jichen Du, Xi Lin
Pages: 472-478 Published online on: 03 May 2018
Article
Combined treatment with PI3K inhibitor BKM120 and PARP inhibitor olaparib is effective in inhibiting the gastric cancer cells with ARID1A deficiency
Lin Yang, Guanghai Yang, Yingjun Ding, Yu Huang, Shunfang Liu, Lei Zhou, Wenjie Wei, Jing Wang, Guangyuan Hu
Pages: 479-487 Published online on: 16 May 2018
Article
Endogenous Leu332Gln mutation in p53 disrupts the tetramerization ability in a canine mammary gland tumor cell line
Kazuhiko Ochiai, Daigo Azakami, Masami Morimatsu, Hinako Hirama, Shota Kawakami, Takayuki Nakagawa, Masaki Michishita, Ai S. Egusa, Takanori Sasaki, Masami Watanabe, Toshinori Omi
Pages: 488-494 Published online on: 02 May 2018
Article
Stable silencing of dll4 gene suppresses the growth and metastasis of esophagus cancer cells by attenuating Akt phosphorylation
Xianzhi Guo, Yingchun Duan, Xiaolei Ye, Lina Hu, Tong Xu, Li Tong, Minghua Yu
Pages: 495-503 Published online on: 08 May 2018
Article
Morusin suppresses A549 cell migration and induces cell apoptosis by downregulating the expression of COX‑2 and VEGF genes
Xiao‑Lu Yin, Yi Lv, Shu Wang, Yu‑Qing Zhang
Pages: 504-510 Published online on: 09 May 2018
Article
Umbilical cord‑derived mesenchymal stem cells can inhibit the biological functions of melanoma A375 cells
Wei Wang, Li Li, Fei Chen, Yu Yang
Pages: 511-517 Published online on: 16 May 2018
Article
Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway
Ling Zhang, Daobin Huang, Decui Shao, Hui Liu, Qing Zhou, Shuyu Gui, Wei Wei, Yuan Wang
Pages: 518-526 Published online on: 16 May 2018
Article
In vitro cytotoxic effect of PARP inhibitor alone and in combination with nab‑paclitaxel on triple‑negative and luminal A breast cancer cells
Mehmet Topçul, İdi̇l Çeti̇n, Suna Özbaş Turan, Melek Özlem Kolusayin Ozar
Pages: 527-535 Published online on: 12 April 2018
Article
Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells
Ju-Yeon Jeon, Jee San Lee, Eun-Ran Park, Yan Nan Shen, Mi-Yeun Kim, Hyun-Jin Shin, Hyun-Yoo Joo, Eung-Ho Cho, Sun Mi Moon, Ui Sup Shin, Sun Hoo Park, Chul Ju Han, Dong Wook Choi, Man Bock Gu, Sang-Bum Kim, Kee-Ho Lee
Pages: 536-544 Published online on: 25 April 2018
Article
Anticancer effects of a novel chroman analog in HeLa cells are associated with G2‑phase arrest and mitochondrial‑mediated apoptosis
Hyunjin Jeong, Yumi Shin, Dong‑Kyoo Kim
Pages: 545-553 Published online on: 27 April 2018
Article
