|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Coleman RE: Clinical features of
metastatic bone disease and risk of skeletal morbidity. Clin Cancer
Res. 12:6243s–6249s. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Steinauer K, Huang DJ, Eppenberger-Castori
S, Amann E and Güth U: Bone metastases in breast cancer: Frequency,
metastatic pattern and non-systemic locoregional therapy. J Bone
Oncol. 3:54–60. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Thomas RJ, Guise TA, Yin JJ, Elliott J,
Horwood NJ, Martin TJ and Gillespie MT: Breast cancer cells
interact with osteoblasts to support osteoclast formation.
Endocrinology. 140:4451–4458. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kearns AE, Khosla S and Kostenuik PJ:
Receptor activator of nuclear factor kappaB ligand and
osteoprotegerin regulation of bone remodeling in health and
disease. Endocr Rev. 29:155–192. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Blair JM, Zhou H, Seibel MJ and Dunstan
CR: Mechanisms of disease: Roles of OPG, RANKL and RANK in the
pathophysiology of skeletal metastasis. Nat Clin Pract Oncol.
3:41–49. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Suda T, Takahashi N, Udagawa N, Jimi E,
Gillespie MT and Martin TJ: Modulation of osteoclast
differentiation and function by the new members of the tumor
necrosis factor receptor and ligand families. Endocr Rev.
20:345–357. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Gonzalez-Suarez E, Jacob AP, Jones J,
Miller R, Roudier-Meyer MP, Erwert R, Pinkas J, Branstetter D and
Dougall WC: RANK ligand mediates progestin-induced mammary
epithelial proliferation and carcinogenesis. Nature. 468:103–107.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Canon JR, Roudier M, Bryant R, Morony S,
Stolina M, Kostenuik PJ and Dougall WC: Inhibition of RANKL blocks
skeletal tumor progression and improves survival in a mouse model
of breast cancer bone metastasis. Clin Exp Metastasis. 25:119–129.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Roodman GD and Dougall WC: RANK ligand as
a therapeutic target for bone metastases and multiple myeloma.
Cancer Treat Rev. 34:92–101. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Von Hoff DD, Layard MW, Basa P, Davis HL
Jr, Von Hoff AL, Rozencweig M and Muggia FM: Risk factors for
doxorubicin-induced congestive heart failure. Ann Intern Med.
91:710–717. 1979. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Luu T, Chung C and Somlo G: Combining
emerging agents in advanced breast cancer. Oncologist. 16:760–771.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Vyas S, Hameed S and Murugaraj V:
Denosumab-associated osteonecrosis of the jaw - a case report. Dent
Update. 41:449–450. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
O'Halloran M, Boyd NM and Smith A:
Denosumab and osteonecrosis of the jaws - the pharmacology,
pathogenesis and a report of two cases. Aust Dent J. 59:516–519.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Vaupel P and Harrison L: Tumor hypoxia:
Causative factors, compensatory mechanisms, and cellular response.
Oncologist. 9 Suppl 5:4–9. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Höckel M and Vaupel P: Tumor hypoxia:
Definitions and current clinical, biologic, and molecular aspects.
J Natl Cancer Inst. 93:266–276. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Harris AL: Hypoxia - a key regulatory
factor in tumour growth. Nat Rev Cancer. 2:38–47. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhong H, De Marzo AM, Laughner E, Lim M,
Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL and Simons
JW: Overexpression of hypoxia-inducible factor 1alpha in common
human cancers and their metastases. Cancer Res. 59:5830–5835.
1999.PubMed/NCBI
|
|
19
|
Rundqvist H and Johnson RS: Tumour
oxygenation: Implications for breast cancer prognosis. J Intern
Med. 274:105–112. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Siclari VA, Mohammad KS, Tompkins DR,
Davis H, McKenna CR, Peng X, Wessner LL, Niewolna M, Guise TA,
Suvannasankha A, et al: Tumor-expressed adrenomedullin accelerates
breast cancer bone metastasis. Breast Cancer Res. 16:4582014.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
de Castro Junior G, Puglisi F, de Azambuja
E, El Saghir NS and Awada A: Angiogenesis and cancer: A cross-talk
between basic science and clinical trials (the ‘do ut des’
paradigm). Crit Rev Oncol Hematol. 59:40–50. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Pugh CW and Ratcliffe PJ: Regulation of
angiogenesis by hypoxia: Role of the HIF system. Nat Med.
9:677–684. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Tang ZN, Zhang F, Tang P, Qi XW and Jiang
J: Hypoxia induces RANK and RANKL expression by activating HIF-1α
in breast cancer cells. Biochem Biophys Res Commun. 408:411–416.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kallergi G, Markomanolaki H, Giannoukaraki
V, Papadaki MA, Strati A, Lianidou ES, Georgoulias V, Mavroudis D
and Agelaki S: Hypoxia-inducible factor-1alpha and vascular
endothelial growth factor expression in circulating tumor cells of
breast cancer patients. Breast Cancer Res. 11:R842009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hiraga T, Kizaka-Kondoh S, Hirota K,
Hiraoka M and Yoneda T: Hypoxia and hypoxia-inducible factor-1
expression enhance osteolytic bone metastases of breast cancer.
Cancer Res. 67:4157–4163. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hansen TN, Sonoda Y and McIlroy MB:
Transfer of oxygen, nitrogen, and carbon dioxide through normal
adult human skin. J Appl Physiol. 49:438–443. 1980. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Bohr C, Hasselbach K and Krogh A: Ueber
emen in biologischen Bezuehung wichtigen Einfluss, den die Kohlen
saurespannung des Blutes anf dessen Samerstoffbinding ubt. Arch
Physiol. 16:402–412. 1904.
|
|
28
|
Sakai Y, Miwa M, Oe K, Ueha T, Koh A,
Niikura T, Iwakura T, Lee SY, Tanaka M and Kurosaka M: A novel
system for transcutaneous application of carbon dioxide causing an
‘artificial Bohr effect’ in the human body. PLoS One. 6:e241372011.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Onishi Y, Kawamoto T, Ueha T, Kishimoto K,
Hara H, Fukase N, Toda M, Harada R, Minoda M, Sakai Y, et al:
Transcutaneous application of carbon dioxide (CO2)
induces mitochondrial apoptosis in human malignant fibrous
histiocytoma in vivo. PLoS One. 7:e491892012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Harada R, Kawamoto T, Ueha T, Minoda M,
Toda M, Onishi Y, Fukase N, Hara H, Sakai Y, Miwa M, et al:
Reoxygenation using a novel CO2 therapy decreases the
metastatic potential of osteosarcoma cells. Exp Cell Res.
319:1988–1997. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Takeda D, Hasegawa T, Ueha T, Imai Y,
Sakakibara A, Minoda M, Kawamoto T, Minamikawa T, Shibuya Y, Akisue
T, et al: Transcutaneous carbon dioxide induces mitochondrial
apoptosis and suppresses metastasis of oral squamous cell carcinoma
in vivo. PLoS One. 9:e1005302014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Onishi Y, Kawamoto T, Ueha T, Hara H,
Fukase N, Toda M, Harada R, Sakai Y, Miwa M, Nishida K, et al:
Transcutaneous application of Carbon Dioxide (CO2)
enhances chemosensitivity by reducing hypoxic conditions in human
malignant fibrous histiocytoma. J Cancer Sci Ther. 4:174–181. 2012.
View Article : Google Scholar
|
|
33
|
Bobrova TS, Kriukova IN, Voronina AN and
Bassalyk LS: Study of the ‘continuous cell antigen’ and the human
gastric mucosa. Biull Eksp Biol Med. 86:744–747. 1978.(In Russian).
PubMed/NCBI
|
|
34
|
Okada Y, Ueno H, Katagiri M, Oneyama T,
Shimomura K, Sakurai S, Mataga I, Moride M and Hasegawa H:
Experimental study of antiangiogenic gene therapy targeting VEGF in
oral cancer. Odontology. 98:52–59. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Oe K, Ueha T, Sakai Y, Niikura T, Lee SY,
Koh A, Hasegawa T, Tanaka M, Miwa M and Kurosaka M: The effect of
transcutaneous application of carbon dioxide (CO2) on
skeletal muscle. Biochem Biophys Res Commun. 407:148–152. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Okada Y, Akisue T, Hara H, Kishimoto K,
Kawamoto T, Imabori M, Kishimoto S, Fukase N, Onishi Y and Kurosaka
M: The effect of bevacizumab on tumour growth of malignant fibrous
histiocytoma in an animal model. Anticancer Res. 30:3391–3395.
2010.PubMed/NCBI
|
|
37
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−∆∆C(T)) Method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Modderman WE, Raap Tuinenburg-Bol AC and
Nijweide PJ: Tartrate-resistant acid phosphatase is not an
exclusive marker for mouse osteoclasts in cell culture. Bone.
12:81–87. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Boyde A, Maconnachie E, Reid SA, Delling G
and Mundy GR: Scanning electron microscopy in bone pathology:
Review of methods, potential and applications. Scan Electron
Microsc. 4:1537–1554. 1986.
|
|
40
|
Kozlow W and Guise TA: Breast cancer
metastasis to bone: Mechanisms of osteolysis and implications for
therapy. J Mammary Gland Biol Neoplasia. 10:169–180. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Bendre MS, Montague DC, Peery T, Akel NS,
Gaddy D and Suva LJ: Interleukin-8 stimulation of
osteoclastogenesis and bone resorption is a mechanism for the
increased osteolysis of metastatic bone disease. Bone. 33:28–37.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Roodman GD: Biology of osteoclast
activation in cancer. J Clin Oncol. 19:3562–3571. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Bryden AA, Hoyland JA, Freemont AJ, Clarke
NW and George NJ: Parathyroid hormone related peptide and receptor
expression in paired primary prostate cancer and bone metastases.
Br J Cancer. 86:322–325. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Miki T, Yano S, Hanibuchi M and Sone S:
Bone metastasis model with multiorgan dissemination of human
small-cell lung cancer (SBC-5) cells in natural killer
cell-depleted SCID mice. Oncol Res. 12:209–217. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Rattigan Y, Hsu JM, Mishra PJ, Glod J and
Banerjee D: Interleukin 6 mediated recruitment of mesenchymal stem
cells to the hypoxic tumor milieu. Exp Cell Res. 316:3417–3424.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Filippi I, Carraro F and Naldini A:
Interleukin-1β affects MDAMB231 breast cancer cell migration under
hypoxia: Role of HIF-1α and NFκB transcription factors. Mediators
Inflamm. 2015:7894142015. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Tang ZN, Zhang F, Tang P, Qi XW and Jiang
J: Hypoxia induces RANK and RANKL expression by activating HIF-1α
in breast cancer cells Biochem Biophys Res Commun. 408:411–416.
2011.
|
|
48
|
Jain RK: Normalization of tumor
vasculature: An emerging concept in antiangiogenic therapy.
Science. 307:58–62. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Vaupel P and Mayer A: Hypoxia in cancer:
Significance and impact on clinical outcome. Cancer Metastasis Rev.
26:225–239. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Miyazawa M, Yasuda M, Fujita M, Hirasawa
T, Kajiwara H, Hirabayashi K, Ogane N, Shimizu M, Asanuma H,
Murakami M, et al: Association of hypoxia-inducible factor-1
expression with histology in epithelial ovarian tumors: A
quantitative analysis of HIF-1. Arch Gynecol Obstet. 279:789–796.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Zeng W, Wan R, Zheng Y, Singh SR and Wei
Y: Hypoxia, stem cells and bone tumor. Cancer Lett. 313:129–136.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Rohwer N and Cramer T: Hypoxia-mediated
drug resistance: Novel insights on the functional interaction of
HIFs and cell death pathways. Drug Resist Updat. 14:191–201. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Schwab LP, Peacock DL, Majumdar D, Ingels
JF, Jensen LC, Smith KD, Cushing RC and Seagroves TN:
Hypoxia-inducible factor 1α promotes primary tumor growth and
tumor-initiating cell activity in breast cancer. Breast Cancer Res.
14:R62012. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Teicher BA: Combination of
perfluorochemical emulsions and carbogen breathing with cancer
chemotherapy. Artif Cells Blood Substit Immobil Biotechnol.
22:1109–1120. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Kawasoe Y, Yokouchi M, Ueno Y, Iwaya H,
Yoshida H and Komiya S: Hyperbaric oxygen as a chemotherapy
adjuvant in the treatment of osteosarcoma. Oncol Rep. 22:1045–1050.
2009.PubMed/NCBI
|
|
56
|
Kaanders JH, Bussink J and van der Kogel
AJ: Clinical studies of hypoxia modification in radiotherapy. Semin
Radiat Oncol. 14:233–240. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Budach W: Radiotherapy in patients with
metastatic breast cancer. Eur J Cancer. 47 Suppl 3:S23–S27. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Blair DA, Glover WE and McArrdle L: The
mechanism of the peripheral vasodilation following carbon dioxide
inhalation in man. Clin Sci. 19:407–423. 1960.
|
|
59
|
Matz H, Orion E and Wolf R: Balneotherapy
in dermatology. Dermatol Ther. 16:132–140. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Hartmann BR, Bassenge E, Pittler M and
Hartmann BR: Effect of carbon dioxide-enriched water and fresh
water on the cutaneous microcirculation and oxygen tension in the
skin of the foot. Angiology. 48:337–343. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Koga T, Niikura T, Lee SY, Okumachi E,
Ueha T, Iwakura T, Sakai Y, Miwa M, Kuroda R and Kurosaka M:
Topical cutaneous CO2 application by means of a novel
hydrogel accelerates fracture repair in rats. J Bone Joint Surg Am.
96:2077–2084. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Trinkaus M, Ooi WS, Amir E, Popovic S,
Kalina M, Kahn H, Singh G, Gainford MC and Clemons M: Examination
of the mechanisms of osteolysis in patients with metastatic breast
cancer. Oncol Rep. 21:1153–1159. 2009.PubMed/NCBI
|
|
63
|
Chen YC, Sosnoski DM and Mastro AM: Breast
cancer metastasis to the bone: Mechanisms of bone loss. Breast
Cancer Res. 12:2152010. View Article : Google Scholar : PubMed/NCBI
|
