Long non‑coding RNAs in small cell lung cancer: A potential opening to combat the disease (Review)

  • Authors:
    • Tian‑Tian Li
    • Rong‑Quan He
    • Jie Ma
    • Zu‑Yun Li
    • Xiao‑Hua Hu
    • Gang Chen
  • View Affiliations

  • Published online on: August 7, 2018     https://doi.org/10.3892/or.2018.6635
  • Pages: 1831-1842
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Abstract

Lung cancer is the top cause of cancer‑associated mortality in men and women worldwide. Small cell lung cancer (SCLC) is a subtype that constitutes ~15% of all lung cancer cases. Long non‑coding RNAs (lncRNAs), possessing no or limited protein‑coding ability, have gained extensive attention as a potentially promising avenue by which to investigate the biological regulation of human cancer. lncRNAs can modulate gene expression at the transcriptional, post‑transcriptional and epigenetic levels. The current review highlights the developing clinical implications and functional roles of lncRNAs in SCLC, and provides directions for their future utilization in the diagnosis and treatment of SCLC.
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October-2018
Volume 40 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Li TT, He RQ, Ma J, Li ZY, Hu XH and Chen G: Long non‑coding RNAs in small cell lung cancer: A potential opening to combat the disease (Review). Oncol Rep 40: 1831-1842, 2018.
APA
Li, T., He, R., Ma, J., Li, Z., Hu, X., & Chen, G. (2018). Long non‑coding RNAs in small cell lung cancer: A potential opening to combat the disease (Review). Oncology Reports, 40, 1831-1842. https://doi.org/10.3892/or.2018.6635
MLA
Li, T., He, R., Ma, J., Li, Z., Hu, X., Chen, G."Long non‑coding RNAs in small cell lung cancer: A potential opening to combat the disease (Review)". Oncology Reports 40.4 (2018): 1831-1842.
Chicago
Li, T., He, R., Ma, J., Li, Z., Hu, X., Chen, G."Long non‑coding RNAs in small cell lung cancer: A potential opening to combat the disease (Review)". Oncology Reports 40, no. 4 (2018): 1831-1842. https://doi.org/10.3892/or.2018.6635