|
1
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kuwano H, Nishimura Y, Oyama T, Kato H,
Kitagawa Y, Kusano M, Shimada H, Takiuchi H, Toh Y, Doki Y, et al:
Guidelines for diagnosis and treatment of carcinoma of the
esophagus April 2012 edited by the Japan esophageal society.
Esophagus. 12:1–30. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Pennathur A, Gibson MK, Jobe BA and
Luketich JD: Oesophageal carcinoma. Lancet. 381:400–412. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lagergren J, Smyth E, Cunningham D and
Lagergren P: Oesophageal cancer. Lancet. 390:2383–2396. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Nitulescu GM, Van De Venter M, Nitulescu
G, Ungurianu A, Juzenas P, Peng Q, Olaru OT, Grădinaru D, Tsatsakis
A, Tsoukalas D, et al: The AKT pathway in oncology therapy and
beyond (Review). Int J Oncol. 53:2319–2331. 2018.PubMed/NCBI
|
|
6
|
Guanen Q, Junjie S, Baolin W, Chaoyang W,
Yajuan Y, Jing L, Junpeng L, Gaili N, Zhongping W and Jun W:
MiR-214 promotes cell metastasis and inhibits apoptosis of
esophageal squamous cell carcinoma via PI3K/AKT/mTOR signaling
pathway. Biomed Pharmacother. 105:350–361. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Zhao H, Chen G, Ye L, Yu H, Li S and Jiang
WG: DOK7V1 influences the malignant phenotype of lung cancer cells
through PI3K/AKT/mTOR and FAK/paxillin signaling pathways. Int J
Oncol. 54:381–389. 2019.PubMed/NCBI
|
|
8
|
Zhao J, Li Z, Chen Y, Zhang S, Guo L, Gao
B, Jiang Y, Tian W, Hao S and Zhang X: MicroRNA-766 inhibits
papillary thyroid cancer progression by directly targeting insulin
receptor substrate 2 and regulating the PI3K/AKT pathway. Int J
Oncol. 54:315–325. 2019.PubMed/NCBI
|
|
9
|
Liu SQ, Xu CY, Wu WH, Fu ZH, He SW, Qin MB
and Huang JA: Sphingosine kinase 1 promotes the metastasis of
colorectal cancer by inducing the epithelial-mesenchymal transition
mediated by the FAK/AKT/MMPs axis. Int J Oncol. 54:41–52.
2019.PubMed/NCBI
|
|
10
|
Dornan GL and Burke JE: Molecular
mechanisms of human disease mediated by oncogenic and primary
immunodeficiency mutations in Class IA phosphoinositide 3-kinases.
Front Immunol. 9:5752018. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Jia Y, Xiao Z, Gongsun X, Xin Z, Shang B,
Chen G, Wang Z and Jiang W: CEP55 promotes the proliferation,
migration and invasion of esophageal squamous cell carcinoma via
the PI3K/AKT pathway. Onco Targets Ther. 11:4221–4232. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Caron E: Cellular functions of the Rap1
GTP-binding protein: A pattern emerges. J Cell Sci. 116:435–440.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Khanna A, Lotfi P, Chavan AJ, Montaño NM,
Bolourani P, Weeks G, Shen Z, Briggs SP, Pots H, Van Haastert PJ,
et al: The small GTPases Ras and Rap1 bind to and control TORC2
activity. Sci Rep. 6:258232016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Sayyah J, Bartakova A, Nogal N, Quilliam
LA, Stupack DG and Brown JH: The Ras-related protein, Rap1A,
mediates thrombinstimulated, integrin-dependent glioblastoma cell
proliferation and tumor growth. J Biol Chem. 289:17689–17698. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Grolez GP and Gkika D: TRPM8 puts the
chill on prostate cancer. Pharmaceuticals (Basel). 9(pii): E442016.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Genova T, Grolez GP, Camillo C, Bernardini
M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D,
Munaron L, et al: TRPM8 inhibits endothelial cell migration via a
non-channel function by trapping the small GTPase Rap1. J Cell
Biol. 216:2107–2130. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lu L, Wang J, Wu Y, Wan P and Yang G:
Rap1A promotes ovarian cancer metastasis via activation of ERK/p38
and notch signaling. Cancer Med. 5:3544–3554. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Rice TW, Ishwaran H, Ferguson MK,
Blackstone EH and Goldstraw P: Cancer of the esophagus and
esophagogastric junction: An eighth edition staging primer. J
Thorac Oncol. 12:36–42. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Xiang J, Bian C, Wang H, Huang S and Wu D:
MiR-203 down-regulates Rap1A and suppresses cell proliferation,
adhesion and invasion in prostate cancer. J Exp Clin Cancer Res.
34:82015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu L, Yan X, Wu D, Yang Y, Li M, Su Y,
Yang W, Shan Z, Gao Y and Jin Z: High expression of Ras-related
protein 1A promotes an aggressive phenotype in colorectal cancer
via PTEN/FOXO3/CCND1 pathway. J Exp Clin Cancer Res. 37:1782018.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chen CH, Chuang HC, Huang CC, Fang FM,
Huang HY, Tsai HT, Su LJ, Shiu LY, Leu S and Chien CY:
Overexpression of Rap-1A indicates a poor prognosis for oral cavity
squamous cell carcinoma and promotes tumor cell invasion via
Aurora-A modulation. Am J Pathol. 182:516–528. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
To JY and Smrcka AV: Activated
heterotrimeric G protein αi subunits inhibit Rap-dependent cell
adhesion and promote cell migration. J Biol Chem. 293:1570–1578.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xiang J, Zang W, Che J, Chen K and Hang J:
Regulation network analysis in the esophageal squamous cell
carcinoma. Eur Rev Med Pharmacol Sci. 16:2051–2056. 2012.PubMed/NCBI
|
|
24
|
Martinelli E, Morgillo F, Troiani T and
Ciardiello F: Cancer resistance to therapies against the
EGFR-RAS-RAF pathway: The role of MEK. Cancer Treat Rev. 53:61–69.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhang T, Jiang K, Zhu X, Zhao G, Wu H,
Deng G and Qiu C: MiR-433 inhibits breast cancer cell growth via
the MAPK signaling pathway by targeting Rap1A. Int J Biol Sci.
14:622–632. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Rodríguez CI, Castro-Pérez E, Prabhakar K,
Block L, Longley BJ, Wisinski JA, Kimple ME and Setaluri V:
EPAC-RAP1 axis-mediated switch in the response of primary and
metastatic melanoma to cyclic AMP. Mol Cancer Res. 15:1792–1802.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Park JY and Juhnn YS: cAMP signaling
increases histone deacetylase 8 expression via the Epac2-Rap1A-AKT
pathway in H1299 lung cancer cells, histone deacetylases and
cancer. Exp Mol Med. 49:e2972017. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Liu M, Hu Y, Zhang MF, Luo KJ, Xie XY, Wen
J, Fu JH and Yang H: MMP1 promotes tumor growth and metastasis in
esophageal squamous cell carcinoma. Cancer Lett. 377:97–104. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Zhang J, Kong R and Sun L: Silencing of
Rab3D suppresses the proliferation and invasion of esophageal
squamous cell carcinoma cells. Biomed Pharmacother. 91:402–407.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kong KL, Kwong DL, Chan TH, Law SY, Chen
L, Li Y, Qin YR and Guan XY: MicroRNA-375 inhibits tumour growth
and metastasis in oesophageal squamous cell carcinoma through
repressing insulin-like growth factor 1 receptor. Gut. 61:33–42.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Yang JW and Choi YL: Genomic profiling of
esophageal squamous cell carcinoma (ESCC)-Basis for precision
medicine. Pathol Res Pract. 213:836–841. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wang K, Johnson A, Ali SM, Klempner SJ,
Bekaii-Saab T, Vacirca JL, Khaira D, Yelensky R, Chmielecki J,
Elvin JA, et al: Comprehensive genomic profiling of advanced
esophageal squamous cell carcinomas and esophageal adenocarcinomas
reveals similarities and differences. Oncologist. 20:1132–1139.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wang K, Li J, Guo H, Xu X, Xiong G, Guan
X, Liu B, Li J, Chen X, Yang K, et al: MiR-196a binding-site SNP
regulates Rap1A expression contributing to esophageal squamous cell
carcinoma risk and metastasis. Carcinogenesis. 33:2147–2154. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Shimada Y, Imamura M, Wagata T, Yamaguchi
N and Tobe T: Characterization of 21 newly established esophageal
cancer cell lines. Cancer. 69:277–284. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Xiao F, Wang X, Wang M, Guan X and Wu M:
Molecular cytogenetic study on four human esophageal cancer cell
lines. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 15:75–77. 1998.(In
Chinese). PubMed/NCBI
|
|
36
|
Tsygankova OM, Ma C, Tang W, Korch C,
Feldman MD, Lv Y, Brose MS and Meinkoth JL: Downregulation of
Rap1GAP in human tumor cells alters cell matrix and cell cell
adhesion. Mol Cell Biol. 30:3262–3274. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Salem ME, Puccini A, Xiu J, Raghavan D,
Lenz HJ, Korn WM, Shields AF, Philip PA, Marshall JL and Goldberg
RM: Comparative molecular analyses of esophageal squamous cell
carcinoma, esophageal adenocarcinoma, and gastric adenocarcinoma.
Oncologist. 23:1319–1327. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Saxton RA and Sabatini DM: mTOR signaling
in growth, metabolism, and disease. Cell. 168:960–976. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Aadam AA and Abe S: Endoscopic submucosal
dissection for superficial esophageal cancer. Dis Esophagus.
31:2018. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zhang YQ, Chen T, Zhang C, Li QL, Chen WF,
Yao LQ, Zhou PH and Xu MD: Endoscopic submucosal dissection for
superficial proximal esophageal neoplasia is highly successful. Ann
Surg. 266:995–999. 2017. View Article : Google Scholar : PubMed/NCBI
|
