Journal Articles
Review
Role of miR‑34 in gastric cancer: From bench to bedside (Review)
Shengwei Xiong, Mingli Hu, Chenyu Li, Xiaodong Zhou, Hongxia Chen
Pages: 1635-1646 Published online on: 16 August 2019
Review
Autophagy modulation in bladder cancer development and treatment (Review)
Faping Li, Hui Guo, Yuxuan Yang, Mingliang Feng, Bin Liu, Xiang Ren, Honglan Zhou
Pages: 1647-1655 Published online on: 21 August 2019
Article
miR‑141 inhibits proliferation, migration and invasion in human hepatocellular carcinoma cells by directly downregulating TGFβR1
Yan Zhao, Zhenghong Xu, Jia Zhou, Hongmei Yang
Pages: 1656-1666 Published online on: 18 September 2019
Article
MicroRNA‑192 inhibits cell proliferation and induces apoptosis in human breast cancer by targeting caveolin 1
Pinjia Chen, Yun Feng, Haige Zhang, Xinpeng Shi, Bin Li, Wencui Ju, Xiurong Yu, Nan Zhang, Xiaoyong Luo
Pages: 1667-1676 Published online on: 30 August 2019
Article
miRNA‑205‑5p functions as a tumor suppressor by negatively regulating VEGFA and PI3K/Akt/mTOR signaling in renal carcinoma cells
Jianjun Huang, Xue Wang, Guobing Wen, Yu Ren
Pages: 1677-1688 Published online on: 10 September 2019
Article
MicroRNA‑4712‑5p promotes proliferation of the vulvar squamous cell carcinoma cell line A431 by targeting PTEN through the AKT/cyclin D1 signaling pathways
Shaojie Yang, Yanyan Zhao, Lufang Wang, Chang Liu, Ye Lu, Zhidong Fang, Hongshuang Shi, Wenyi Zhang, Xin Wu
Pages: 1689-1698 Published online on: 17 September 2019
Article
miR‑139‑3p suppresses the invasion and migration properties of breast cancer cells by targeting RAB1A
Wei Zhang, Jing Xu, Ke Wang, Xiaojiang Tang, Jianjun He
Pages: 1699-1708 Published online on: 29 August 2019
Article
Synergistic combination of chemo‑phototherapy based on temozolomide/ICG‑loaded iron oxide nanoparticles for brain cancer treatment
Young Min Kwon, Jae‑Young Je, Seung Heon Cha, Yunok Oh, Won Ho Cho
Pages: 1709-1724 Published online on: 21 August 2019
Article
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression
Ji‑Min Li, Guan‑Min Jiang, Liang Zhao, Fang Yang, Wei‑Qi Yuan, Hao Wang, Yi‑Qin Luo
Pages: 1725-1734 Published online on: 22 August 2019
Article
Emetine exhibits anticancer activity in breast cancer cells as an antagonist of Wnt/β‑catenin signaling
Qi Sun, Qiuxia Fu, Shiyue Li, Junjun Li, Shanshan Liu, Zhongyuan Wang, Zijie Su, Jiaxing Song, Desheng Lu
Pages: 1735-1744 Published online on: 22 August 2019
Article
In vivo effects of mutant RHOA on tumor formation in an orthotopic inoculation model
Takashi Nishizawa, Kiyotaka Nakano, Etsuko Fujii, Daisuke Komura, Yoshie Kuroiwa, Chisako Ishimaru, Makoto Monnai, Hiroyuki Aburatani, Shumpei Ishikawa, Masami Suzuki
Pages: 1745-1754 Published online on: 03 September 2019
Article
Disrupting myddosome assembly in diffuse large B‑cell lymphoma cells using the MYD88 dimerization inhibitor ST2825
Xin Wang, Yuan Tan, Zhenglan Huang, Ningshu Huang, Miao Gao, Fangzhu Zhou, Jing Hu, Wenli Feng
Pages: 1755-1766 Published online on: 19 August 2019
Article
The four‑microRNA signature identified by bioinformatics analysis predicts the prognosis of nasopharyngeal carcinoma patients
Siwei Zhang, Wenxing Yue, Yan Xie, Lingzhi Liu, Shen Li, Wei Dang, Shuyu Xin, Li Yang, Xingyu Zhai, Pengfei Cao, Jianhong Lu
Pages: 1767-1780 Published online on: 16 September 2019
Article
Co‑culturing with hypoxia pre‑conditioned mesenchymal stem cells as a new strategy for the prevention of irradiation‑induced fibroblast‑to‑myofibroblast transition
Lei Zhuang, Wenzheng Xia, Meng Hou
Pages: 1781-1792 Published online on: 23 August 2019
Article
Serum proteomic analysis of melanoma patients with immunohistochemical profiling of primary melanomas and cultured cells: Pilot study
Jan Kučera, Karolína Strnadová, Barbora Dvořánková, Lukáš Lacina, Ivana Krajsová, Jiří Štork, Hana Kovářová, Helena Kupcová Skalníková, Petr Vodička, Jan Motlík, Pavel Dundr, Karel Smetana, Ondřej Kodet
Pages: 1793-1804 Published online on: 17 September 2019
Article
Nicotinamide N‑methyltransferase induces the proliferation and invasion of squamous cell carcinoma cells
Young‑Sool Hah, Hee Young Cho, Sun Young Jo, Young Sook Park, Eun Phil Heo, Tae‑Jin Yoon
Pages: 1805-1814 Published online on: 16 September 2019
Article
Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway
Qinfang Li, Aiping Xu, Yuan Chu, Tao Chen, Hongqi Li, Liqing Yao, Pinghong Zhou, Meidong Xu
Pages: 1815-1824 Published online on: 12 September 2019
Article
MicroRNA‑203a‑3p is a candidate tumor suppressor that targets thrombospondin 2 in colorectal carcinoma
Zhenyuan Qian, Lijie Gong, Yiping Mou, Yong Han, Shusen Zheng
Pages: 1825-1832 Published online on: 12 September 2019
Article
Transcriptomic analysis and identification of prognostic biomarkers in cholangiocarcinoma
Hanyu Li, Junyu Long, Fucun Xie, Kai Kang, Yue Shi, Weiyu Xu, Xiaoqian Wu, Jianzhen Lin, Haifeng Xu, Shunda Du, Yiyao Xu, Haitao Zhao, Yongchang Zheng, Jin Gu
Pages: 1833-1842 Published online on: 17 September 2019
Article
Curcumin inhibits cell proliferation and migration in NSCLC through a synergistic effect on the TLR4/MyD88 and EGFR pathways
Lanfeng Zhang, Xingyu Tao, Qiaofen Fu, Chunlei Ge, Ruilei Li, Zhen Li, Ye Zhu, Hui Tian, Qiaolin Li, Min Liu, Hongyan Hu, Baozhen Zeng, Zhuyin Lin, Chunyan Li, Rongcheng Luo, Xin Song
Pages: 1843-1855 Published online on: 14 August 2019
Article
Clinical significance and prospective molecular mechanism of C‑C motif chemokine receptors in patients with early‑stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy
Xin Zhou, Xiwen Liao, Xiangkun Wang, Ketuan Huang, Chengkun Yang, Tingdong Yu, Junqi Liu, Chuangye Han, Guangzhi Zhu, Hao Su, Wei Qin, Quanfa Han, Zhengqian Liu, Jianlv Huang, Yizhen Gong, Xinping Ye, Tao Peng
Pages: 1856-1868 Published online on: 13 August 2019
Article
Expression of LXR‑β, ABCA1 and ABCG1 in human triple‑negative breast cancer tissues
Hailing Pan, Yue Zheng, Qi Pan, Honglei Chen, Fuchun Chen, Jie Wu, Dingxin Di
Pages: 1869-1877 Published online on: 14 August 2019
Article
Metastatic renal cell carcinoma cells growing in 3D on poly‑D‑lysine or laminin present a stem‑like phenotype and drug resistance
Klaudia K. Brodaczewska, Zofia F. Bielecka, Kamila Maliszewska‑Olejniczak, Cezary Szczylik, Camillo Porta, Ewa Bartnik, Anna M. Czarnecka
Pages: 1878-1892 Published online on: 18 September 2019
Article
Tanshinone IIA inhibits glucose metabolism leading to apoptosis in cervical cancer
Zhigang Liu, Wenhe Zhu, Xiangyu Kong, Xi Chen, Xinyi Sun, Wei Zhang, Ruowen Zhang
Pages: 1893-1903 Published online on: 27 August 2019
Article
Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells
Sung‑Hyun Kim, Gang‑Sik Choo, Eun‑Seon Yoo, Joong‑Seok Woo, So‑Hee Han, Jae‑Han Lee, Ji‑Youn Jung
Pages: 1904-1914 Published online on: 28 August 2019
Article
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells
Zhan Wang, Min Zhang, Rong Shan, Yu‑Jie Wang, Juan Chen, Juan Huang, Lun‑Quan Sun, Wei‑Bing Zhou
Pages: 1915-1923 Published online on: 23 August 2019
Article
LINC00461 affects the survival of patients with renal cell carcinoma by acting as a competing endogenous RNA for microRNA‑942
Yicheng Chen, Jinkui He, Changju Su, Huan Wang, Yuanlei Chen, Wenhao Guo, Yining Li, Guoqing Ding
Pages: 1924-1934 Published online on: 12 September 2019
Article
Downregulated IGFBP7 facilitates liver metastasis by modulating epithelial‑mesenchymal transition in colon cancer
Yuanfei Li, Yanfeng Xi, Guoqiang Zhu, Junmei Jia, He Huang, Yanyan Liu, Yarong Guo, Lixin Liu
Pages: 1935-1945 Published online on: 06 September 2019
Article
lncRNA‑u50535 promotes the progression of lung cancer by activating CCL20/ERK signaling
Wei Wei, Xiaoliang Zhao, Jianquan Zhu, Lianmin Zhang, Yulong Chen, Bin Zhang, Yue Li, Meng Wang, Zhenfa Zhang, Changli Wang
Pages: 1946-1956 Published online on: 05 September 2019
Article
miR‑378a‑3p inhibits cellular proliferation and migration in glioblastoma multiforme by targeting tetraspanin 17
Xiao‑Bing Guo, Xiao‑Chao Zhang, Peng Chen, Li‑Mei Ma, Zhi‑Qiang Shen
Pages: 1957-1971 Published online on: 20 August 2019
Article
Increased UCP1 expression in the perirenal adipose tissue of patients with renal cell carcinoma
Xueqin Li, Gongcheng Wang, Juan Liu, Guoxian Ding
Pages: 1972-1980 Published online on: 10 September 2019
Article
Gene expression and prognosis of insulin‑like growth factor‑binding protein family members in non‑small cell lung cancer
Jiao Wang, Zhi‑Guo Hu, Dan Li, Ji‑Xion Xu, Zhen‑Guo Zeng
Pages: 1981-1995 Published online on: 16 September 2019
Article
Diagnostic and prognostic values of C‑X‑C motif chemokine ligand 3 in patients with colon cancer
Guo‑Tian Ruan, Yi‑Zhen Gong, Xi‑Wen Liao, Shuai Wang, Wei Huang, Xiang‑Kun Wang, Guang‑Zhi Zhu, Cun Liao, Feng Gao
Pages: 1996-2008 Published online on: 19 September 2019
Article
A novel deep learning architecture outperforming ‘off‑the‑shelf’ transfer learning and feature‑based methods in the automated assessment of mammographic breast density
Eleftherios Trivizakis, Georgios S. Ioannidis, Vasileios D. Melissianos, Georgios Z. Papadakis, Aristidis Tsatsakis, Demetrios A. Spandidos, Kostas Marias
Pages: 2009-2015 Published online on: 12 September 2019
Article
WT1 regulates cyclin A1 expression in K562 cells
Sony Pandey, Mustafa Moazam, Nirmala Ghimirey, Steven J. Kuerbitz, Gail C. Fraizer
Pages: 2016-2028 Published online on: 21 August 2019
Article
Efficient primary culture model of patient‑derived tumor cells from colorectal cancer using a Rho‑associated protein kinase inhibitor and feeder cells
Hye Kyung Hong, Dae Hee Pyo, Tae Won Kim, Nak Hyeon Yun, Yeo Song Lee, Su Jeong Song, Woo Yong Lee, Yong Beom Cho
Pages: 2029-2038 Published online on: 20 August 2019
Article
Trk inhibitor GNF‑5837 suppresses the tumor growth, survival and migration of renal cell carcinoma
Yicheng Chen, Huan Wang, Yuanlei Chen, Mingchao Wang, Guoqing Ding, Tao Li
Pages: 2039-2048 Published online on: 28 August 2019
Article
PD‑L1/PD‑1 axis serves an important role in natural killer cell‑induced cytotoxicity in osteosarcoma
Ming‑Lei Zhang, Li Chen, Yan‑Jiao Li, Da‑Liang Kong
Pages: 2049-2056 Published online on: 03 September 2019
Article
High blood levels of soluble OX40 (CD134), an immune costimulatory molecule, indicate reduced survival in patients with advanced colorectal cancer
Ryoichi Sawada, Yoshinori Arai, Yukiko Sagawa, Yusuke Nagata, Takashi Nishimura, Masaaki Noguchi, Katsushi Amano, Seiji Arihiro, Masayuki Saruta, Sadamu Homma
Pages: 2057-2064 Published online on: 06 September 2019
Article
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion
Xiao Han, Xiaoxue Li, Huan Liu, Hongshuo Zhang, Aoying Li, Ming Dong, Yuefei Xu, Bin Yan, Linlin Sui, Ying Kong
Pages: 2065-2074 Published online on: 16 September 2019
Article
Synchronous co‑expression of Id‑1 and nuclear NF‑κB p65 promotes cervical cancer progression and malignancy, and is associated with a poor prognosis and chemosensitivity
Zhao Wu, Jinke Li, Yi Zhang, Lina Hu, Xue Peng
Pages: 2075-2086 Published online on: 05 September 2019
Article
Lung carcinoma therapy using epidermal growth factor receptor‑targeted lipid polymeric nanoparticles co‑loaded with cisplatin and doxorubicin
Yan Nan
Pages: 2087-2096 Published online on: 18 September 2019
Article
PI3K p110α inhibition sensitizes cervical cancer cells with aberrant PI3K signaling activation to PARP inhibitor BMN673
Penglong Cao, Yingxin Wang, Yunyi Lv, Nan Jiang, Lin Zhong, Xiaolu Ma, Xiaoguang Xiao, Dapeng Ding, Juebin Gu, Lin Lin, Shijun Li
Pages: 2097-2107 Published online on: 13 September 2019
Article
Tannic acid synergistically enhances the anticancer efficacy of cisplatin on liver cancer cells through mitochondria‑mediated apoptosis
Nana Geng, Xiang Zheng, Mingsong Wu, Lei Yang, Xueying Li, Jindong Chen
Pages: 2108-2116 Published online on: 16 August 2019
Article
Clinical significance and biological role of KLF17 as a tumour suppressor in colorectal cancer
Xun Jiang, Tong‑Yi Shen, Helei Lu, Chenzhang Shi, Zhongchen Liu, Huanlong Qin, Feng Wang
Pages: 2117-2129 Published online on: 18 September 2019
Article
The oncogenic role of NKAP in the growth and invasion of colon cancer cells
Weibin Shu, Guoqin Liu, Yunpeng Dai, Alei Feng, Zheng Chen, Junqing Han, Xinyu Li
Pages: 2130-2138 Published online on: 18 September 2019
Article
Curcumin decreases epithelial‑mesenchymal transition by a Pirin‑dependent mechanism in cervical cancer cells
Victor Aedo‑Aguilera, Diego Carrillo‑Beltrán, Gloria M. Calaf, Juan P. Muñoz, Nahir Guerrero, Julio C. Osorio, Julio C. Tapia, Oscar León, Hector R. Contreras, Francisco Aguayo
Pages: 2139-2148 Published online on: 21 August 2019
Article
PTEN/AKT signaling mediates chemoresistance in refractory acute myeloid leukemia through enhanced glycolysis
Min Jeong Ryu, Jeongsu Han, Soo Jeong Kim, Min Joung Lee, Xianshu Ju, Yu Lim Lee, Jeong Hwan Son, Jianchen Cui, Yunseon Jang, Woosuk Chung, Ik‑Chan Song, Gi Ryang Kweon, Jun Young Heo
Pages: 2149-2158 Published online on: 12 September 2019
Article
DNA methylation of sarcosine dehydrogenase (SARDH) loci as a prognosticator for renal cell carcinoma
Mehrdad Mazdak, Hossein Tezval, Janne Carmen Callauch, Natalia Dubrowinskaja, Inga Peters, Carsten Bokemeyer, Jörg Hennenlotter, Arnulf Stenzl, Markus A. Kuczyk, Jürgen Serth
Pages: 2159-2168 Published online on: 09 September 2019
Article
