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Breast and prostate glands affected by environmental substances (Review)

  • Authors:
    • Tammy C. Bleak
    • Gloria M. Calaf
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    Affiliations: Instituto de Alta Investigación, Universidad de Tarapacá, Arica, Arica 1000000, Chile
    Copyright: © Bleak et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 20
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    Published online on: February 5, 2021
       https://doi.org/10.3892/or.2021.7971
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Abstract

Environmental endocrine disruptor chemicals are substances that can alter the homeostasis of the endocrine system in living organisms. They can be released from several products used in daily activities. Once in the organism, they can disrupt the endocrine function by mimicking or blocking naturally occurring hormones due to their similar chemical structure. This endocrine disruption is the most important cause of the well‑known hormone‑associate types of cancer. Additionally, it is decisive to determine the susceptibility of each organ to these compounds. Therefore, the present review aimed to summarize the effect of different environmental substances such as bisphenol A, dichlorodiphenyltrichloroethane and polychlorinated biphenyls in both the mammary and the prostate tissues. These organs were chosen due to their association with the hormonal system and their common features in carcinogenic mechanisms. Outcomes derived from the present review may provide evidence that should be considered in future debates regarding the effects of endocrine disruptors on carcinogenesis.
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Bleak TC and Calaf GM: Breast and prostate glands affected by environmental substances (Review). Oncol Rep 45: 20, 2021.
APA
Bleak, T.C., & Calaf, G.M. (2021). Breast and prostate glands affected by environmental substances (Review). Oncology Reports, 45, 20. https://doi.org/10.3892/or.2021.7971
MLA
Bleak, T. C., Calaf, G. M."Breast and prostate glands affected by environmental substances (Review)". Oncology Reports 45.4 (2021): 20.
Chicago
Bleak, T. C., Calaf, G. M."Breast and prostate glands affected by environmental substances (Review)". Oncology Reports 45, no. 4 (2021): 20. https://doi.org/10.3892/or.2021.7971
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Spandidos Publications style
Bleak TC and Calaf GM: Breast and prostate glands affected by environmental substances (Review). Oncol Rep 45: 20, 2021.
APA
Bleak, T.C., & Calaf, G.M. (2021). Breast and prostate glands affected by environmental substances (Review). Oncology Reports, 45, 20. https://doi.org/10.3892/or.2021.7971
MLA
Bleak, T. C., Calaf, G. M."Breast and prostate glands affected by environmental substances (Review)". Oncology Reports 45.4 (2021): 20.
Chicago
Bleak, T. C., Calaf, G. M."Breast and prostate glands affected by environmental substances (Review)". Oncology Reports 45, no. 4 (2021): 20. https://doi.org/10.3892/or.2021.7971
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