Journal Articles

Article Open Access

Circular RNA hsa_circ_0001666 sponges miR‑330‑5p, miR‑193a‑5p and miR‑326, and promotes papillary thyroid carcinoma progression via upregulation of ETV4

Ying Qi, Jingni He, Ying Zhang, Lidong Wang, Yifan Yu, Baiyu Yao, Zhong Tian

Article Number: 50 Published online on: 03 March 2021
Review Open Access

Oncolytic adenovirus: A tool for reversing the tumor microenvironment and promoting cancer treatment (Review)

Xiaoxi Wang, Liping Zhong, Yongxiang Zhao

Article Number: 49 Published online on: 02 March 2021
Article

Upregulation of SKA3 enhances cell proliferation and correlates with poor prognosis in hepatocellular carcinoma

Jianxin Tang, Jing Liu, Jinjun Li, Ziming Liang, Kaining Zeng, Haibo Li, Zhenlin Zhao, Li Zhou, Nan Jiang

Article Number: 48 Published online on: 02 March 2021
Article Open Access

Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1

Su-Yeon Lee, Jinie Kwon, Kyung-Ah Lee

Article Number: 47 Published online on: 01 March 2021
Article Open Access

HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63‑mediated tight junction molecules and p21‑mediated growth arrest

Akito Kakiuchi, Takuya Kakuki, Kizuku Ohwada, Makoto Kurose, Atsushi Kondoh, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Yakuto Kaneko, Takumi Konno, Takayuki Kohno, Tetsuo Himi, Ken-Ichi Takano, Takashi Kojima

Article Number: 46 Published online on: 01 March 2021
Article Open Access

Circ_0000003 regulates glutamine metabolism and tumor progression of tongue squamous cell carcinoma via the miR‑330‑3p/GLS axis

Cuijuan Qian, Shihang Chen, Sen Li, Yichao Wang, Jun Yao

Article Number: 45 Published online on: 26 February 2021
Article Open Access

Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide

Zhang-Jian Yang, Le-Ling Zhang, Qiu-Chen Bi, Li-Jun Gan, Min-Jun Wei, Tao Hong, Ren-Jie Tan, Xue-Mei Lan, Li-Hua Liu, Xiao-Jian Han, Li-Ping Jiang

Article Number: 44 Published online on: 25 February 2021
Review Open Access

SIRT1 and gynecological malignancies (Review)

Jiayu Chen, Houzao Chen, Lingya Pan

Article Number: 43 Published online on: 24 February 2021
Article Open Access

STK31 upregulation is associated with chromatin remodeling in gastric cancer and induction of tumorigenicity in a xenograft mouse model

Dong Hyuck Bae, Hee-Jin Kim, Byoung-Ha Yoon, Jong-Lyul Park, Mirang Kim, Seon-Kyu Kim, Seon-Young Kim, Sang-Il Lee, Kyu-Sang Song, Yong Sung Kim

Article Number: 42 Published online on: 23 February 2021
Article

Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel

Anthony Murphy, Nirmal Roy, Hong Sun, Chunyuan Jin, Max Costa

Article Number: 41 Published online on: 23 February 2021
Article Open Access

lncRNA MEG3 inhibits pituitary tumor development by participating in cell proliferation, apoptosis and EMT processes

Xuejian Wang, Xiangdong Li, Zhifeng Wang

Article Number: 40 Published online on: 23 February 2021
Article Open Access

Roles of the H19/microRNA‑675 axis in the proliferation and epithelial‑mesenchymal transition of human cutaneous squamous cell carcinoma cells

Wenqing Zhang, Kaili Zhou, Xue Zhang, Chenglong Wu, Dan Deng, Zhirong Yao

Article Number: 39 Published online on: 22 February 2021
Article Open Access

Ginsenoside compound K exerts antitumour effects in renal cell carcinoma via regulation of ROS and lncRNA THOR

Shuqiu Chen, Haihong Ye, Fanger Gong, Suming Mao, Cong Li, Bin Xu, Yu Ren, Rui Yu

Article Number: 38 Published online on: 22 February 2021
Article

Downregulation of triggering receptor expressed on myeloid cells 1 inhibits invasion and migration of liver cancer cells by mediating macrophage polarization

Minmin Chen, Ruimin Lai, Xiaoyu Lin, Wei Chen, Huizhen Wu, Qi Zheng

Article Number: 37 Published online on: 19 February 2021
Review

Effects of m6A modifications on signaling pathways in human cancer (Review)

Fangyuan Liu, Xiulan Su

Article Number: 36 Published online on: 19 February 2021
Review

Research progress on tumour‑associated macrophages in gastric cancer (Review)

Zidi Zhou, Zhilong Yang, Jingzhi Wang, Qiang Wang, Heng Zhang, Xiaoli Ju

Article Number: 35 Published online on: 19 February 2021
Article Open Access

Corilagin induces human glioblastoma U251 cell apoptosis by impeding activity of (immuno)proteasome

Xianyun Qin, Jilan Liu, Dongfeng Pan, Wenyuan Ma, Panpan Cheng, Feng Jin

Article Number: 34 Published online on: 19 February 2021
Review

Anticancer effects and potential mechanisms of ginsenoside Rh2 in various cancer types (Review)

Haibo Zhang, Song Park, Hai Huang, Eungyung Kim, Junkoo Yi, Seong-Kyoon Choi, Zaeyoung Ryoo, Myoungok Kim

Article Number: 33 Published online on: 19 February 2021
Article Open Access

Kaempferol exhibits a synergistic effect with doxorubicin to inhibit proliferation, migration, and invasion of liver cancer

Guang Yang, Jun Xing, Batuer Aikemu, Jing Sun, Minhua Zheng

Article Number: 32 Published online on: 18 February 2021
Correction Open Access

[Corrigendum] Silencing of type Iγ phosphatidylinositol phosphate kinase suppresses ovarian cancer cell proliferation, migration and invasion

Siyu Cao, Chunhua Chen, Junli Xue, Yan Huang, Xiaofeng Yang, Kun Ling

Article Number: 31 Published online on: 18 February 2021
Correction Open Access

[Corrigendum] Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate

Ioana Macașoi, Ioana Zinuca Pavel, Alina Elena Moacă, Ștefana Avram, Vlad Laurențiu David, Dorina Coricovac, Alexandra Mioc, Demetrios A. Spandidos, Aristidis Tsatsakis, Codruța Șoica, Victor Dumitrașcu, Cristina Dehelean

Article Number: 30 Published online on: 18 February 2021
Article

Anaplastic lymphoma kinase inhibitor NVP‑TAE684 suppresses the proliferation of human pancreatic adenocarcinoma cells

Hong-Quan Duong, Van Thai Than, Huyen-Trang Nguyen, Phuong-Thoa Nguyen, Huyen Trang Ha Thi, Thi Ngoc Ha Bui, Vu Phuong Linh Dang, Thi-Thanh Dinh, Kyu Sic You, The-Hung Dang, Yeon-Sun Seong

Article Number: 28 Published online on: 18 February 2021
Article Open Access

Mechanism of acquired 5FU resistance and strategy for overcoming 5FU resistance focusing on 5FU metabolism in colon cancer cell lines

Tomonari Suetsugu, Ryutaro Mori, Manabu Futamura, Masahiro Fukada, Hideharu Tanaka, Itaru Yasufuku, Yuta Sato, Yoshinori Iwata, Takeharu Imai, Hisashi Imai, Yoshihiro Tanaka, Naoki Okumura, Nobuhisa Matsuhashi, Takao Takahashi, Kazuhiro Yoshida

Article Number: 27 Published online on: 18 February 2021
Review

Neoadjuvant therapy for pancreatic cancer: Limitations and advances of response assessment (Review)

Jianwei Xu, Hanxiang Zhan, Feng Li, Sanyuan Hu, Lei Wang

Article Number: 26 Published online on: 18 February 2021
Article

Ferroptosis inducer erastin downregulates androgen receptor and its splice variants in castration‑resistant prostate cancer

Yanrong Yang, Taiyuan Liu, Cheng Hu, Hongyan Xia, Wei Liu, Junyu Chen, Shan Wu, Yu Jiang, Yang Xu, Wanxia Liu, Lijing Zhao

Article Number: 25 Published online on: 15 February 2021
Review Open Access

Signs of carcinogenicity induced by parathion, malathion, and estrogen in human breast epithelial cells (Review)

Gloria M. Calaf, Tammy C. Bleak, Debasish Roy

Article Number: 24 Published online on: 11 February 2021
Review

Direct and indirect anticancer effects of hyperthermic intraperitoneal chemotherapy on peritoneal malignancies (Review)

Ying Zhang, Yumin Wu, Jun Wu, Chen Wu

Article Number: 23 Published online on: 10 February 2021
Article Open Access

Melatonin sensitizes esophageal cancer cells to 5‑fluorouracil via promotion of apoptosis by regulating EZH2 expression

Mengti Zhang, Mengli Zhang, Ruijia Li, Rui Zhang, Yueli Zhang

Article Number: 22 Published online on: 10 February 2021
Article

Lipid droplet storage promotes murine pancreatic tumor growth

Jeremy J. Grachan, Martin Kery, Amato J. Giaccia, Nicholas C. Denko, Ioanna Papandreou

Article Number: 21 Published online on: 09 February 2021
Review Open Access

Breast and prostate glands affected by environmental substances (Review)

Tammy C. Bleak, Gloria M. Calaf

Article Number: 20 Published online on: 05 February 2021
Article Open Access

Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts in vitro cytostatic effects in human colorectal cancer via activating the ROS/p38 and AKT signaling pathways

Ping Zhang, Xiaohui Yuan, Tingting Yu, Huakun Huang, Chunmei Yang, Lulu Zhang, Shengdong Yang, Xiaoji Luo, Jinyong Luo

Article Number: 19 Published online on: 05 February 2021
Article

Inhibitor of apoptosis protein Livin promotes tumor progression and chemoradioresistance in human anaplastic thyroid cancer

Hee Kyung Kim, Sun-Ae Kim, Eun Kyung Jung, Kyung-Hwa Lee, Joon Kyoo Lee, Ho-Cheol Kang, Young-Eun Joo, Sang Chul Lim, Tae Mi Yoon

Article Number: 18 Published online on: 05 February 2021
Review Open Access

Emerging roles of circular RNAs in non‑small cell lung cancer (Review)

Shanshan Li, Yize Liu, Guanzhen Qiu, Yinzhou Luo, Xiang Li, Fei Meng, Nanyang Li, Tiance Xu, Yong Wang, Baoli Qin, Shuyue Xia

Article Number: 17 Published online on: 03 February 2021
Article Open Access

MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein

Ying Zhuang, Xiang Li, Peng Zhan, Guoliang Pi, Gu Wen

Article Number: 16 Published online on: 03 February 2021
Article Open Access

miR‑146b‑5p inhibits tumorigenesis and metastasis of gallbladder cancer by targeting Toll‑like receptor 4 via the nuclear factor‑κB pathway

Bin Ouyang, Ningfeng Pan, Haifeng Zhang, Chuanming Xing, Wu Ji

Article Number: 15 Published online on: 03 February 2021
Article Open Access

Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma cells is downregulated upon inhibition of BRAF

Karolina Uranowska, Tanja Kalic, Veronika Valtsanidis, Melitta Kitzwögerer, Heimo Breiteneder, Christine Hafner

Article Number: 14 Published online on: 02 February 2021
Article Open Access

Exosome-mediated radiosensitizing effect on neighboring cancer cells via increase in intracellular levels of reactive oxygen species

Ai Nakaoka, Makiko Nakahana, Sachiko Inubushi, Hiroaki Akasaka, Mohammed Salah, Yoshiko Fujita, Hikaru Kubota, Mennaallah Hassan, Ryo Nishikawa, Naritoshi Mukumoto, Takeaki Ishihara, Daisuke Miyawaki, Takashi Sasayama, Ryohei Sasaki

Article Number: 13 Published online on: 02 February 2021
Article Open Access

Exosomal miR‑663b exposed to TGF‑β1 promotes cervical cancer metastasis and epithelial‑mesenchymal transition by targeting MGAT3

Xuewu You, Ying Wang, Jinyu Meng, Sai Han, Lu Liu, Yu Sun, Junhua Zhang, Shuqin Sun, Xinyue Li, Wenxiong Sun, Yajie Dong, Youzhong Zhang

Article Number: 12 Published online on: 02 February 2021
Article Open Access

Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT

Hao Zhou, Yichong Ning, Guirong Zeng, Chang Zhou, Xiaofeng Ding

Article Number: 11 Published online on: 02 February 2021
Review Open Access

Molecular features and gene expression signature of metastatic colorectal cancer (Review)

Martina Poturnajova, Tatiana Furielova, Sona Balintova, Silvia Schmidtova, Lucia Kucerova, Miroslava Matuskova

Article Number: 10 Published online on: 02 February 2021
Review

Mechanisms and functions of long non‑coding RNAs in glioma (Review)

Xingjie Chen, Gaochao Guo, Yalin Lu, Shuaishuai Wang, Yu Zhang, Qiang Huang

Article Number: 9 Published online on: 01 February 2021
Article Open Access

LINC00649 promotes bladder cancer malignant progression by regulating the miR‑15a‑5p/HMGA1 axis

Xuanyu Chen, Song Chen

Article Number: 8 Published online on: 01 February 2021
Article Open Access

CD44 activation state regulated by the CD44v10 isoform determines breast cancer proliferation

Qian Guo, Yiwen Liu, Yiqing He, Yan Du, Guoliang Zhang, Cuixia Yang, Feng Gao

Article Number: 7 Published online on: 01 February 2021
Article Open Access

Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium‑mediated cell signaling

Sang Yoon Park, Jong-Tae Kim, Eun Sun Park, Yo Sep Hwang, Hyang Ran Yoon, Kyoung Eun Baek, Haiyoung Jung, Suk Ran Yoon, Bo Yeon Kim, Hee Jun Cho, Hee Gu Lee

Article Number: 6 Published online on: 29 January 2021
Article

Long non‑coding RNA LOC284454 promotes hepatocellular carcinoma cell invasion and migration by inhibiting E‑cadherin expression

Lili Han, Weixiao Zhou, Fei Wu

Article Number: 5 Published online on: 28 January 2021
Article

LRPPRC contributes to the cisplatin resistance of lung cancer cells by regulating MDR1 expression

Yunfeng Hu, Jie Cui, Lei Jin, Yani Su, Xiaozhi Zhang

Article Number: 4 Published online on: 28 January 2021
Article Open Access

Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong

Article Number: 3 Published online on: 27 January 2021
Article Open Access

Combination of miR‑143 and miR‑506 reduces lung and pancreatic cancer cell growth through the downregulation of cyclin‑dependent kinases

A.K.M. Nawshad Hossian, Gerardo G. Mackenzie, George Mattheolabakis

Article Number: 2 Published online on: 27 January 2021
Article Open Access

Semaphorin 4D is a potential biomarker in pediatric leukemia and promotes leukemogenesis by activating PI3K/AKT and ERK signaling pathways

Hongchao Jiang, Jiaolian Tang, Lijuan Qiu, Zhen Zhang, Shulan Shi, Li Xue, Liyue Kui, Tilong Huang, Weiwei Nan, Bailing Zhou, Canchun Zhao, Ming Yu, Qiangming Sun

Article Number: 1 Published online on: 27 January 2021
Journal Cover

April-2021
Volume 45 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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