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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2004 Volume 24 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon

Masuko Katoh, Masaru Katoh
Pages: 757-763
Published online on: 01 April 2004

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Review

Single-chain antibodies: A therapeutic modality for cancer gene therapy (Review)

Charles A. Leath, Joanne T. Douglas, David T. Curiel, Ronald D. Alvarez
Pages: 765-771
Published online on: 01 April 2004

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Article

Microarray profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines

S. G. Gray, C.-N. Qian, K. Furge, X. Guo, B. T. Teh
Pages: 773-795
Published online on: 01 April 2004

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Review

Acyclic retinoid in the chemoprevention of hepatocellular carcinoma (Review)

Soichi Kojima, Masataka Okuno, Rie Matsushima-Nishiwaki, Scott L. Friedman, Hisataka Moriwaki
Pages: 797-805
Published online on: 01 April 2004

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Article

Expression of p53 protein as a predictor of the response to 5-fluorouracil and cisplatin chemotherapy in human gastrointestinal cancer cell lines evaluated with apoptosis by use of thin layer collagen gel

Nobuhisa Matsuhashi, Masanao Saio, Atsushi Matsuo, Yasuyuki Sugiyama, Shigetoyo Saji
Pages: 807-813
Published online on: 01 April 2004

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Article

Relationship between the expression of extracellular signal-regulated kinase 1/2 and the dissociation of pancreatic cancer cells: Involvement of ERK1/2 in the dissociation status of cancer cells

Xiaodong Tan, Hiroshi Egami, Shinji Ishikawa, Takashi Kurizaki, Yasuhiro Tamori, Eiji Takai, Masahiko Hirota, Michio Ogawa
Pages: 815-820
Published online on: 01 April 2004

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Article

Expression of lipoxygenase in human prostate cancer and growth reduction by its inhibitors

Masahide Matsuyama, Rikio Yoshimura, Makoto Mitsuhashi, Taro Hase, Kenji Tsuchida, Yoshiaki Takemoto, Yutaka Kawahito, Hajime Sano, Tatsuya Nakatani
Pages: 821-827
Published online on: 01 April 2004

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Article

The diagnostic utility of human papillomavirus-testing in combination with immunohistochemistry in advanced gynaecologic pelvic tumours: A new diagnostic approach

Tjoung-Won Park, Oliver Zivanovic, Ingo Theuerkauf, Barbara Dürkop, Juan José Hernando, Matthias Simon, Reinhard Büttner, Walther Kuhn
Pages: 829-836
Published online on: 01 April 2004

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Article

Down-regulation of matrix-invasive potential of human liver cancer cells by type I interferon and a histone deacetylase inhibitor sodium butyrate

Fumihiko Kaneko, Hidetsugu Saito, Yoshimasa Saito, Kanji Wakabayashi, Nobuhiro Nakamoto, Shinichiro Tada, Hidekazu Suzuki, Satoshi Tsunematsu, Naoki Kumagai, Hiromasa Ishii
Pages: 837-845
Published online on: 01 April 2004

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Article

Microarray analysis of differentially expressed genes associated with human ovarian cancer

Byeong-Chel Lee, Kiweon Cha, Shalom Avraham, Hava Karsenty Avraham
Pages: 847-851
Published online on: 01 April 2004

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Article

Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-associated hepatocellular carcinoma

Alfred S.L. Cheng, Henry L.Y. Chan, Ka F. To, Wai K. Leung, Ka K. Chan, Choong T. Liew, Joseph J.Y. Sung
Pages: 853-860
Published online on: 01 April 2004

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Article

Minimal residual disease detection in breast cancer: Improved sensitivity using cytokeratin 19 and epidermal growth factor receptor RT-PCR

Vicki S. Fellowes, Anne Husebekk, Ronald E. Gress, Barbara A. Vance
Pages: 861-867
Published online on: 01 April 2004

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Article

Protein phosphatase inhibitor-1 mRNA expression correlates with neoplastic transformation of epithelial liver cells and progression of hepatocellular carcinomas

Eiman Aleem, Thomas Flohr, Heinz Walter Thielmann, Peter Bannasch, Doris Mayer
Pages: 869-877
Published online on: 01 April 2004

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Article

Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ

Jinsong Liu, Atac Baykal, Kar-Ming Fung, Jennifer A. Thompson-Lanza, Ashraful Hoque, Scott M. Lippman, Aysegul Sahin
Pages: 879-884
Published online on: 01 April 2004

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Article

Proteomic profiling in microdissected hepatocellular carcinoma tissue using ProteinChip® technology

Christian Melle, Roland Kaufmann, Merten Hommann, Annett Bleul, Dominik Driesch, Günther Ernst, Ferdinand Von Eggeling
Pages: 885-891
Published online on: 01 April 2004

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Article

Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors

Guang Xu, Wanghai Zhang, Paula Bertram, Xiao Feng Zheng, Howard McLeod
Pages: 893-900
Published online on: 01 April 2004

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Article

Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs

Daqing Wang, Yukui Li, Dong Yu, Sam S. Song, Ekambar R. Kandimalla, Sudhir Agrawal
Pages: 901-908
Published online on: 01 April 2004

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Article

Dendritic cell-based immunotherapy of cancer with carcinoembryonic antigen-derived, HLA-A24-restricted CTL epitope: Clinical outcomes of 18 patients with metastatic gastrointestinal or lung adenocarcinomas

Yuji Ueda, Tsuyoshi Itoh, Ikuei Nukaya, Ichiro Kawashima, Kaori Okugawa, Yutaro Yano, Yoshiki Yamamoto, Kei Naitoh, Keiji Shimizu, Kenichiro Imura, Nobuaki Fuji, Hitoshi Fujiwara, Toshiya Ochiai, Hirosumi Itoi, Teruhisa Sonoyama, Akeo Hagiwara, Kazutoh Takesako, Hisakazu Yamagishi
Pages: 909-917
Published online on: 01 April 2004

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Review

Alphavirus vectors for cancer gene therapy (Review)

Ryuya Yamanaka
Pages: 919-923
Published online on: 01 April 2004

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Article

Expression and alternative splicing pattern of human telomerase reverse transcriptase in human lung cancer cells

Masachika Fujiwara, Hiroshi Kamma, Wenwen Wu, Makoto Hamasaki, Setsuko Kaneko, Hisashi Horiguchi, Miwa Matsui-Horiguchi, Hiroaki Satoh
Pages: 925-930
Published online on: 01 April 2004

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Article

STAT3 and MAPK in human lung cancer tissues and suppression of oncogenic growth by JAB and dominant negative STAT3

Yukio Seki, Noriko Suzuki, Munehisa Imaizumi, Takashi Iwamoto, Noriyasu Usami, Yuichi Ueda, Michinari Hamaguchi
Pages: 931-934
Published online on: 01 April 2004

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Article

Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors

On Hee Kim, Jun Hee Lim, Kyung Jin Woo, Young-Ho Kim, Ing-Nyol Jin, Sang Tae Han, Jong-Wook Park, Taeg Kyu Kwon
Pages: 935-941
Published online on: 01 April 2004

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Article

Non-small cell lung cancer as a target disease for herpes simplex type 1 thymidine kinase - ganciclovir gene therapy

Ann-Marie Määttä, Anni Tenhunen, Tiina Pasanen, Outi Meriläinen, Riikka Pellinen, Kimmo Mäkinen, Esko Alhava, Jarmo Wahlfors
Pages: 943-949
Published online on: 01 April 2004

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Article

Wild-type p53 gene transfer into mutated p53 HT29 cells improves sensitivity to photodynamic therapy via induction of apoptosis

Muriel Barberi-Heyob, Pierre-Olivier Védrine, Jean-Louis Merlin, Régine Millon, Joseph Abecassis, Marie-France Poupon, François Guillemin
Pages: 951-958
Published online on: 01 April 2004

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Article

Locoregional immunotherapy of malignant ascites from gastric cancer using DTH-oriented doses of the streptococcal preparation OK-432: Treatment of Th1 dysfunction in the ascites microenvironment

Yoshiyuki Yamaguchi, Akiko Ohshita, Yoshiharu Kawabuchi, Jun Hihara, Eiji Miyahara, Kosuke Noma, Tetsuya Toge
Pages: 959-966
Published online on: 01 April 2004

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Article

HER2/neu-derived peptides recognized by both cellular and humoral immune systems in HLA-A2+ cancer patients

Yuki Ishihara, Mamoru Harada, Koichi Azuma, Mayumi Tamura, Hiroki Shomura, Teruhiko Fujii, Kyogo Itoh, Shigeki Shichijo
Pages: 967-975
Published online on: 01 April 2004

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Article

Conventional and array-based comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine cervix

Yasuo Hirai, Yasutaka Kawamata, Nobuhiro Takeshima, Reiko Furuta, Tomoyuki Kitagawa, Tokuichi Kawaguchi, Katsuhiko Hasumi, Sachiko Sugai, Tetsuo Noda
Pages: 977-986
Published online on: 01 April 2004

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Article

Identification of differentially expressed genes in colorectal adenoma compared to normal tissue by suppression subtractive hybridization

Nicolas Wentzensen, Birgit Wilz, Peter Findeisen, Rudolf Wagner, Wolfgang Dippold, Magnus Von Knebel Doeberitz, Johannes Gebert
Pages: 987-994
Published online on: 01 April 2004

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Article

Induction by hypoxia combined with low glucose or low bicarbonate and high posttranslational stability upon reoxygenation contribute to carbonic anhydrase IX expression in cancer cells

Monika Rafajová, Miriam Zatovicová, Richard Kettmann, Jaromír Pastorek, Silvia Pastoreková
Pages: 995-1004
Published online on: 01 April 2004

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Article

Detection of (NAD(P)H:Quinone oxidoreductase-1, EC 1.6.99.2) 609C↷T and 465C↷T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP

Roger M. Phillips, Saurajyoti Basu, John E. Brown, G. Michael Flannigan, Paul M. Loadman, Sandie W. Martin, Brian Naylor, Rajiv Puri, Tariq Shah
Pages: 1005-1010
Published online on: 01 April 2004

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Article

Imprinting status of DLK1 gene in brain tumors and lymphomas

Dong Yin, Dong Xie, Sven De Vos, Gentao Liu, Carl W. Miller, Keith L. Black, H. Phillip Koeffler
Pages: 1011-1015
Published online on: 01 April 2004

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Article

Modulation of Janus kinase 2 by cisplatin in cancer cells

Hui Song, Vernon K. Sondak, Dwayne L. Barber, Thomas J. Reid, Jiayuh Lin
Pages: 1017-1026
Published online on: 01 April 2004

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Article

Induction of the early response protein EGR-1 in human tumour cells after ionizing radiation is correlated with a reduction of repair of lethal lesions and an increase of repair of sublethal lesions

Nicolaas A.P. Franken, Rosemarie Ten Cate, Chris Van Bree, Jaap Haveman
Pages: 1027-1031
Published online on: 01 April 2004

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Article

Identification and characterization of human GUKH2 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 1033-1038
Published online on: 01 April 2004

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Review

Mutations in DNA mismatch repair genes: Implications for DNA damage signaling and drug sensitivity (Review)

Andre Fedier, Daniel Fink
Pages: 1039-1047
Published online on: 01 April 2004

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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